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Expert System Lecture Module-16.

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Presentation on theme: "Expert System Lecture Module-16."— Presentation transcript:

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Rules and Expert Systems

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Analytical Expert (ARD) (m/f/d)

About the role.

Major accountabilities:

• Designing, planning, supporting the execution as well as interpreting and reporting results of scientific experiments for the development and timely supply of drug substances (DS) and drug products (DP) intended for clinical use in late stage development and potential commercialization.
• Writing & reviewing analytical documents (e.g Analytical procedures, Specifications, Product characterization reports, Validation protocols/reports, Stability protocols/reports as well as Batch records compilation and line function material disposition for stability and release testing) and aligning the corresponding activities within a global project team.
• Managing interactions with internal and external stakeholders, including outsourced activities to CROs by providing scientific and technical guidance whenever necessary.
• Proactively identifying scientific, technological and GMP challenges, propose creative solutions and communicate key issues to the appropriate management level and respective technical project team.
• Working according to appropriate SOPs, GMP, Quality Directives, Health and Safety & internal Novartis guidelines.

Minimum Requirements:

• Minimum: Bachelor in analytical chemistry or equivalent with significant experience in analytical development of drugs. Desirable: Advanced degree in a relevant life science scientific area (e.g. Master, Ph.D. or equivalent in chemistry / pharmaceutical or analytical science).
• Preferably 5 years’ experience in the pharmaceutical industry with a track record in GMP activities for development or marketed products.
• Broad scientific knowledge in chemistry, pharmaceutical or analytical sciences, ability to perform in a global and highly dynamic environment.
• Advanced knowledge of analytical techniques and associated processes (e.g. HPLC and corresponding Chromatographic Data System, Dissolution rate, Quality management systems, statistical evaluation tools ...).
• Good presentation skills and scientific/technical writing skills and associated IT Tools.
• Fluent in English (oral and writing), German is advantageous.

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Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture

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Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Expert Systems

Jul 30, 2014

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Expert Systems. Learning Objectives:. By the end of this topic you should be able to: explain what is meant by an expert system describe the components of an expert system describe the applications of an expert system. Expert Systems. In everyday life:. Expert Systems.

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Learning Objectives: By the end of this topic you should be able to: • explain what is meant by an expert system • describe the components of an expert system • describe the applications of an expert system

Expert Systems In everyday life:

Expert Systems In everyday life: • humans interpret information to gain knowledge

Expert Systems In everyday life: • humans interpret information to gain knowledge • this knowledge is used as the basis for making decisions

Expert Systems In everyday life: • humans interpret information to gain knowledge • this knowledge is used as the basis for making decisions An expert system is:

Expert Systems In everyday life: • humans interpret information to gain knowledge • this knowledge is used as the basis for making decisions An expert system is: • a computer program, used to help with a decision making process

Expert Systems In everyday life: • humans interpret information to gain knowledge • this knowledge is used as the basis for making decisions An expert system is: • a computer program, used to help with a decision making process • aka rules-based system, knowledge system

An Expert System is:

An Expert System: • is a computer program • is made up of a set of rules • analyses information about a specific type of problem. • trys to solve a problem in the same way as a human expert • has a narrow range of expertise • gives answers to questions • asks questions based on previous responses • can show how it reached conclusions • can learn from experience (heuristic) • is based on probabilities, not certainties • based on research into Artificial Intelligence (AI)

Expert System - Definition • has three components:

Expert System - 3 components • knowledge base • set of rules • consists of If...Then… rules • e.g. IF it is raining THEN I need to take an umbrella with me

Expert System - 3 components • knowledge base • set of rules • consists of If...Then… rules • e.g. IF it is raining THEN I need to take an umbrella with me • inference engine • evaluates data against the knowledge base • to provide a conclusion

Expert System - 3 components • knowledge base • set of rules • consists of If...Then… rules • e.g. IF it is raining THEN I need to take an umbrella with me • inference engine • evaluates data against the knowledge base • to provide a conclusion • user interface • displays questions to be completed by the operator • displays conclusions as output

Examples of Expert Systems

Examples of Expert Systems • weather forecasting

Examples of Expert Systems • weather forecasting • fault diagnosis • electrical goods, cars

Examples of Expert Systems • weather forecasting • fault diagnosis • electrical goods, cars • medical diagnosis • diagnose blood infections, identify tumours

Examples of Expert Systems • weather forecasting • fault diagnosis • electrical goods, cars • medical diagnosis • diagnose blood infections, identify tumours • facial recognition

Examples of Expert Systems • weather forecasting • fault diagnosis • electrical goods, cars • medical diagnosis • diagnose blood infections, identify tumours • facial recognition • careers advice

Examples of Expert Systems • weather forecasting • fault diagnosis • electrical goods, cars • medical diagnosis • diagnose blood infections, identify tumours • facial recognition • careers advice • credit scoring • identifying whether or not an individual should be granted credit

Examples of Expert Systems • weather forecasting • fault diagnosis • electrical goods, cars • medical diagnosis • diagnose blood infections, identify tumours • facial recognition • careers advice • credit scoring • identifying whether or not an individual should be granted credit • financial planning • what if we …..?”

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