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Theses and Dissertations

Check Cornell’s library catalog , which lists the dissertations available in our library collection.

The print thesis collection in Uris Library is currently shelved on Level 3B before the Q to QA regular-sized volumes. Check with the library staff for the thesis shelving locations in other libraries (Mann, Catherwood, Fine Arts, etc.).

ProQuest Dissertations and Theses

According to ProQuest, coverage begins with 1637. With more than 2.4 million entries,  ProQuest Dissertations and Theses Global  is the starting point for finding citations to doctoral dissertations and master’s theses. Dissertations published from 1980 forward include 350-word abstracts written by the author. Master’s theses published from 1988 forward include 150-word abstracts. UMI also offers over 1.8 million titles for purchase in microfilm or paper formats. The full text of more than 930,000 are available in PDF format for immediate free download. Use  Interlibrary Loan  for the titles not available as full text online.

Foreign Dissertations at the Center for Research Libraries

To search for titles and verify holdings of dissertations at the Center for Research Libraries (CRL), use the CRL catalog . CRL seeks to provide comprehensive access to doctoral dissertations submitted to institutions outside the U. S. and Canada (currently more than 750,000 titles). One hundred European universities maintain exchange or deposit agreements with CRL. Russian dissertation abstracts in the social sciences are obtained on microfiche from INION.  More detailed information about CRL’s dissertation holdings .

Please see our resource guide on dissertations and theses for additional resources and support.

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Alum Alexander Levine Honored with Charles A. Caramello Distinguished Dissertation Award

University of Maryland Department of Computer Science alum Alexander Levine (Ph.D. '23, computer science) has been awarded the Charles A. Caramello Distinguished Dissertation Award for his dissertation titled "Scalable Methods for Robust Machine Learning." Levine, now a postdoctoral fellow at the University of Texas at Austin , focused on developing machine learning models that maintain accuracy amid distortions. The award ceremony is scheduled for Tuesday, May 14, at the Stamp Student Union. The award is for the dissertation he completed in 2023.

The Charles A. Caramello Distinguished Dissertation Award is given annually by the Graduate School to recognize dissertations that provide highly original contributions that make an unusually significant contribution to the discipline. Levine is among four recipients of the award this year.

Awardees receive an honorarium of $1,000. Additionally, they may be nominated for further recognition at the national level through the CGS/ProQuest Distinguished Dissertation Award competition, which selects outstanding dissertations from across the country to honor achievements in graduate research.

“I feel honored that my work has been recognized by this award,” Levine said. “I am deeply thankful for all of the support I received during my time at UMD from my advisor, my collaborators, my dissertation committee and the rest of the UMD computer science community. I am fortunate to have worked with such talented people on such interesting problems.”

Advised by Associate Professor Soheil Feizi , Levine's dissertation introduces innovative methods for ensuring the robustness of machine learning models, specifically in scenarios where input data may be subtly altered or distorted, including malicious tampering. This research is particularly relevant as machine learning applications become increasingly prevalent in areas requiring high reliability and security.

Levine explained that practitioners can implement these systems more confidently in safety-critical applications by developing machine learning techniques with well-understood robustness guarantees. He noted that the capabilities of machine-learning-based systems have expanded dramatically in just the last couple of years, increasing their use in various sectors. Levine emphasized the growing importance of ensuring these systems' robustness as their applications broaden.

Levine is currently expanding his research focus.

“At UT Austin, my research focus has shifted to representation learning for sequential decision-making tasks,” Levine shared. “In particular, I have been working on frameworks that allow deep learning to be used in combination with search-based planning techniques, so that we can benefit from both the powerful capabilities of modern deep learning and the interpretability, flexibility and efficiency of classical planning methods. ”

Levine received the Larry S. Davis Doctoral Dissertation Award in the Fall of 2023 . Named in honor of Computer Science Professor Emeritus Larry Davis , the award, given by UMD’s Department of Computer Science, highlighted dissertations that were exceptional in their technical depth and potential for significant impact.

—Story by Samuel Malede Zewdu, CS Communications 

The Department welcomes comments, suggestions and corrections.  Send email to editor [-at-] cs [dot] umd [dot] edu .

Graduate Education

Office of graduate and postdoctoral education, phd defense by ben metcalf, may 1, 2024.

In partial fulfillment of the requirements for the degree of

Doctor of Philosophy in Bioinformatics

in the School of Biological Sciences

Benjamin Metcalf

Defends his thesis:

The Interrelationship Between Bacterial and Societal Factors Drives Pneumococcal Transmission and Disease Progression

Wednesday, May 1, 2024

BME Whitaker building, Room 1214

Thesis Advisor:

Dr. Sam Brown, Advisor

School of Biological Sciences

Georgia Institute of Technology Co-Advisor: Dr. Kristofer Wollein Waldetoft, Co-Advisor

Georgia Institute of Technology

Committee Members:

Dr. Marvin Whiteley

Dr. Joshua Weitz

Previous Affiliation: School of Biological Sciences

Georgia Institute of Technology Current Affiliation: School of Biology University of Maryland

Dr. Joe Lachance

Dr. Bernard Beall

Division of Bacterial Diseases

Centers for Disease Control and Prevention

Streptococcus pneumoniae (Spn) is a gram-positive opportunistic pathogen and a leading cause of bacterial pneumonia, meningitis, and sepsis worldwide. Spn is typically categorized by serotype and in most cases colonizes the nasopharynx asymptomatically (defined as carriage). On rare occasions, it can spread into normally sterile sites and cause severe infections known as invasive pneumococcal disease (IPD). Both the ability of Spn to cause these life-threatening illnesses ( i.e., its invasiveness) and the length of time in carriage ( i.e., its carriage duration) vary substantially across serotypes. IPD cases can occur in isolation or, occasionally, spread as localized outbreaks, often arising within disadvantaged communities like people experiencing homelessness (PEH) and people who inject drugs (PWID). In this dissertation, we seek to explore how pneumococcal life-history traits, host demographic factors, and the interrelationships between them can impact invasive disease at the population level.

In Chapter Two we show that variation in carriage duration can confound serotype invasiveness measurements and identify the best performing metrics for invasiveness. Our results also support previous work showing that when invasion occurs, it does so at or near the time of carriage acquisition. In Chapter Three we show that Spn transmission is host density-dependent, resulting in a stratification of serotypes by human population density. The fourth chapter provides evidence that the risk of IPD and IPD clustering is in part governed by human social conditions, with increased risks in disadvantaged populations. In the final discussion chapter, we provide a broader discussion of potential future directions of research, building on the work in this thesis.

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• dissertation defense essays economics crime and health michael topper

Dissertation Defense: “Essays in the Economics of Crime and Health” Michael Topper

Michael Topper , PhD Candidate, University of California, Santa Barbara

Michael Topper is an applied microeconomist with a particular interest in the economics of crime. His first paper, The Effects of Fraternity Moratoriums on Alcohol Offenses and Sexual Assaults is published in the Journal of Human Resources. Currently, his work focuses on policing. His job market paper, The Unintended Consequences of Policing Technology: Evidence from ShotSpotter (with Toshio Ferrazares), examines the unintended consequences of a wide-spread gunshot detection technology.

Michael is a devoted educator who emphasizes quality open-source materials. He assisted the creation of two courses at UCSB, Data Wrangling for Economics (Econ 145/Econ 245), and has authored a free online accompanying course textbook, Data Wrangling for Economists (with Danny Klinenberg). Moreover, Michael is the creator of the software R package Panelsummary which aims to streamline reproducible research.

Event Details

Join us to hear Michael’s dissertation defense. He will be defending his dissertation, “Essays in the Economics of Crime and Health” To access a copy of the  dissertation, you must have an active UCSB NetID and password.

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Department of Economics • College of Letters & Science • UC Santa Barbara 2023 © Regents of the University of California

MEMP PhD Thesis Defense (4:00pm): Mingyu Yang

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MIT 32-141 and Zoom (See below for full information)

Myelination diseases of the central nervous system: Artificial Axons as  in vitro  models of chemomechanical cues

Myelination is a key biological process wherein glial cells such as oligodendrocytes wrap myelin around neuronal axons, forming an insulative sheath that accelerates signal propagation down the axon. A major obstacle to understanding myelination is the challenge of visualizing and reproducibly quantifying this inherently three-dimensional process  in vitro . To this end, Van Vliet et al. previously developed Artificial Axons (AAs), a biocompatible platform consisting of 3D-printed axon mimics that can be ensheathed by oligodendrocytes  in vitro . In this thesis, we advance and apply the Artificial Axon platform to create  in vitro  models of lesion-like environments to elucidate the mechanisms underlying myelination diseases. 

First, we improve the existing AA platform to investigate how biophysical cues affect myelin wrapping by rat oligodendrocytes. We build a new high-resolution 3D printer (HR-3DP) that can fabricate AAs with sub-kilopascal elastic moduli and <2 µm diameters. We demonstrate that the extent of myelin ensheathment by rat oligodendrocytes is sensitive to the Young’s modulus, diameter, and density of axons, indicating that each of these biophysical cues may play a causal role in influencing an oligodendrocyte’s propensity to myelinate. We further demonstrate that the responses of oligodendrocytes to pro-myelinating compounds are dependent on axon stiffness, and that the relative ranking of drug efficacies differs between stiff and compliant axons.

Second, we demonstrate the promise of using AAs to model lesion-like environments using human oligodendrocytes. We used AAs to model the impact of myelin debris and microglia co-culture on myelin ensheathment, recapitulating  in vivo  results demonstrating a dose-dependent effect of myelin debris on myelin ensheathment. We further demonstrate the compatibility of the AAs with myelination by human oligodendrocytes derived from induced pluripotent stem cells (iPSCs). In particular, we explore the effect of the apolipoprotein (ApoE) genotype on myelin ensheathment, based on clinical data that individuals with the ApoE4 allele exhibit worsened MS prognosis compared to individuals with the ApoE3 allele. We demonstrate how targeted perturbations to cholesterol metabolism pathways differentially impact ApoE3 vs. ApoE4 human oligodendrocytes. In sum, these results demonstrate the potential of AAs to elucidate the cellular and molecular mechanisms of myelination in the context of human disease. Thesis Supervisor: Krystyn J. Van Vliet, PhD Vice President of Research and Innovation, Professor, Materials Science and Engineering; Biomedical Engineering, Cornell University

Thesis Co-Supervisor: Aristide Gumyusenge, PhD Merton C. Flemings (1951) Career Development Professor, Materials Science and Engineering, MIT

Thesis Committee Chair: Darrell G. Irvine, PhD Professor, Materials Science and Engineering; Bioengineering, MIT

Thesis Reader: Kristin Galetta, MD Clinical Assistant Professor, Neurology & Neurological Sciences, Stanford University ------------------------------------------------------------------------------------------------------

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Topic: Mingyu Yang MEMP PhD Thesis Defense Time: Wednesday, May 8, 2024, 4:00 PM Eastern Time (US and Canada)

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