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Your research project: a step-by-step guide for the first-time researcher_Walliman_2005

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research and methodology project pdf

Daniel Kashikola

Ponsian P R O T Ntui

This book is the outcome of more than four decades of experience of the author in teaching and research field. Research is a creative process and the topic of research methodology is complex and varied. The basic premise for writing this book is that research methods can be taught and learnt. The emphasis is on developing a research outlook and a frame of mind for carrying out research. The book presents current methodological techniques used in interdisciplinary research along with illustrated and worked out examples. This book is well equipped with fundamentals of research and research designs. All efforts have been made to present Research, its meaning, intention and usefulness. Focussed in designing of research programme, selection of variables, collection of data and their analysis to interpret the data are discussed extensively. Statistical tools are complemented with examples, making the complicated subject like statistics simplest usable form. The importance of software, like MS Excel, SPSS, for statistical analyses is included. Written in a simple language, it covers all aspects of management of data with details of statistical tools required for analysis in a research work. Complete with a glossary of key terms and guides to further reading, this book is an essential text for anyone coming to research for the first time and is widely relevant across the disciplines of sciences. This book is designed to introduce Masters, and doctoral students to the process of conducting scientific research in the life sciences, social sciences, education, public health, and related scientific disciplines. It conforms to the core syllabus of many universities and institutes. The target audience for this book includes those are going to start research as graduate students, junior researchers, and professors teaching courses on research methods. The book entitled “A guide to Research Methodology for Beginners” is succinct and compact by design focusing only on essential concepts rather than burden students with a voluminous text on top of their assigned readings. The book is structured into the following nine chapters. Chapter-1: What is Scientific Research? Chapter-2: Literature Review Chapter-3: How to develop a Research Questions & Hypotheses Chapter-4: Research Methods and the Research Design Chapter-5: Concept of Variables, Levels and Scales of Measurements for Data collection Chapter-6: Data Analysis, Management and Presentation Chapter-7: Tips for Writing Research Report Chapter-8: Glossary Related to Research Methodology Chapter-9: References It is a comprehensive and compact source for basic concepts in research and can serve as a stand-alone text or as a supplement to research readings in any doctoral seminar or research methods class. The target audience for this book includes those are going to start research as graduate students, junior researchers, and professors teaching courses on research methods.

Modern Language Journal

Fred Ntedika Mvumbi

A thesis/Dissertation, as one piece of work, should be a text that addresses the issues of the community; all divisions and sub-divisions ought to be interconnected and interrelated to become a process leading to one goal. Thus, the text has threefold dimension. The first is that few people know the underlying principle of a research; that is the wisdom behind the idea, the efforts and the pains of carrying out a research in a particular field of knowledge. The second is a request to students to fall in love and to have passion for the kind of study they want to undertake; this increases the motivation and disposes them to go extra miles for comprehensive and immense discovery where understanding, application and generation of new knowledge take place. The third reason, which is equally important, maybe the most important in writing this text, concerns the organization of the report; in this case the presentation of a thesis/dissertation. Students should be more and more motivated to carry out research in various fields of knowledge, particularly when they have means; and postgraduate students should be increasingly encouraged to take part in research initiatives, for this helps to find new meanings of life.

LUWAGA ERIC

This section presents an introduction of the study and review of the theories that are adopted in the study. These underpin the theoretical perspectives adopted in the process, the Statement of the problem, objectives and the scope of the study.

Essential Tremor

So you’re a student at university looking to do research and write a dissertation (thesis)? This book is for you. It’s an essential guide to the research process covering all stages from planning to doing to writing up and proofing. The book also has a unique section on publishing your dissertation for those who wish to push their academic career along. Unlike other books, it does not assume that you have infinite time and resources to conduct your research. It recognises that at this level you probably have six months or less to finish the dissertation and gives practical advice on which studies are feasible and which are not. The book gets on top of the research terminology by giving concise, working definitions of the key terms, which will appeal to international students. With over 30 years of experience in leading and teaching research in a variety of fields, Dr Michael Cribb has pulled together all his wisdom and knowledge in one book to help guide students through their first big research project.

Bhimashankar Sanga

Skyfox Publishing Group

Dr. T. Vel murugan

This book cover the following topics: 1. Research Concepts 2. Research Problem 3. Research Design 4.Sampling Techniques 5. Data collection, Analysis & Report Writing

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Research Methodology Example

Detailed Walkthrough + Free Methodology Chapter Template

If you’re working on a dissertation or thesis and are looking for an example of a research methodology chapter , you’ve come to the right place.

In this video, we walk you through a research methodology from a dissertation that earned full distinction , step by step. We start off by discussing the core components of a research methodology by unpacking our free methodology chapter template . We then progress to the sample research methodology to show how these concepts are applied in an actual dissertation, thesis or research project.

If you’re currently working on your research methodology chapter, you may also find the following resources useful:

  • Research methodology 101 : an introductory video discussing what a methodology is and the role it plays within a dissertation
  • Research design 101 : an overview of the most common research designs for both qualitative and quantitative studies
  • Variables 101 : an introductory video covering the different types of variables that exist within research.
  • Sampling 101 : an overview of the main sampling methods
  • Methodology tips : a video discussion covering various tips to help you write a high-quality methodology chapter
  • Private coaching : Get hands-on help with your research methodology

Free Webinar: Research Methodology 101

PS – If you’re working on a dissertation, be sure to also check out our collection of dissertation and thesis examples here .

FAQ: Research Methodology Example

Research methodology example: frequently asked questions, is the sample research methodology real.

Yes. The chapter example is an extract from a Master’s-level dissertation for an MBA program. A few minor edits have been made to protect the privacy of the sponsoring organisation, but these have no material impact on the research methodology.

Can I replicate this methodology for my dissertation?

As we discuss in the video, every research methodology will be different, depending on the research aims, objectives and research questions. Therefore, you’ll need to tailor your literature review to suit your specific context.

You can learn more about the basics of writing a research methodology chapter here .

Where can I find more examples of research methodologies?

The best place to find more examples of methodology chapters would be within dissertation/thesis databases. These databases include dissertations, theses and research projects that have successfully passed the assessment criteria for the respective university, meaning that you have at least some sort of quality assurance.

The Open Access Thesis Database (OATD) is a good starting point.

How do I get the research methodology chapter template?

You can access our free methodology chapter template here .

Is the methodology template really free?

Yes. There is no cost for the template and you are free to use it as you wish.

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research and methodology project pdf

Cultural Relativity and Acceptance of Embryonic Stem Cell Research

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research and methodology project pdf

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There is a debate about the ethical implications of using human embryos in stem cell research, which can be influenced by cultural, moral, and social values. This paper argues for an adaptable framework to accommodate diverse cultural and religious perspectives. By using an adaptive ethics model, research protections can reflect various populations and foster growth in stem cell research possibilities.

INTRODUCTION

Stem cell research combines biology, medicine, and technology, promising to alter health care and the understanding of human development. Yet, ethical contention exists because of individuals’ perceptions of using human embryos based on their various cultural, moral, and social values. While these disagreements concerning policy, use, and general acceptance have prompted the development of an international ethics policy, such a uniform approach can overlook the nuanced ethical landscapes between cultures. With diverse viewpoints in public health, a single global policy, especially one reflecting Western ethics or the ethics prevalent in high-income countries, is impractical. This paper argues for a culturally sensitive, adaptable framework for the use of embryonic stem cells. Stem cell policy should accommodate varying ethical viewpoints and promote an effective global dialogue. With an extension of an ethics model that can adapt to various cultures, we recommend localized guidelines that reflect the moral views of the people those guidelines serve.

Stem cells, characterized by their unique ability to differentiate into various cell types, enable the repair or replacement of damaged tissues. Two primary types of stem cells are somatic stem cells (adult stem cells) and embryonic stem cells. Adult stem cells exist in developed tissues and maintain the body’s repair processes. [1] Embryonic stem cells (ESC) are remarkably pluripotent or versatile, making them valuable in research. [2] However, the use of ESCs has sparked ethics debates. Considering the potential of embryonic stem cells, research guidelines are essential. The International Society for Stem Cell Research (ISSCR) provides international stem cell research guidelines. They call for “public conversations touching on the scientific significance as well as the societal and ethical issues raised by ESC research.” [3] The ISSCR also publishes updates about culturing human embryos 14 days post fertilization, suggesting local policies and regulations should continue to evolve as ESC research develops. [4]  Like the ISSCR, which calls for local law and policy to adapt to developing stem cell research given cultural acceptance, this paper highlights the importance of local social factors such as religion and culture.

I.     Global Cultural Perspective of Embryonic Stem Cells

Views on ESCs vary throughout the world. Some countries readily embrace stem cell research and therapies, while others have stricter regulations due to ethical concerns surrounding embryonic stem cells and when an embryo becomes entitled to moral consideration. The philosophical issue of when the “someone” begins to be a human after fertilization, in the morally relevant sense, [5] impacts when an embryo becomes not just worthy of protection but morally entitled to it. The process of creating embryonic stem cell lines involves the destruction of the embryos for research. [6] Consequently, global engagement in ESC research depends on social-cultural acceptability.

a.     US and Rights-Based Cultures

In the United States, attitudes toward stem cell therapies are diverse. The ethics and social approaches, which value individualism, [7] trigger debates regarding the destruction of human embryos, creating a complex regulatory environment. For example, the 1996 Dickey-Wicker Amendment prohibited federal funding for the creation of embryos for research and the destruction of embryos for “more than allowed for research on fetuses in utero.” [8] Following suit, in 2001, the Bush Administration heavily restricted stem cell lines for research. However, the Stem Cell Research Enhancement Act of 2005 was proposed to help develop ESC research but was ultimately vetoed. [9] Under the Obama administration, in 2009, an executive order lifted restrictions allowing for more development in this field. [10] The flux of research capacity and funding parallels the different cultural perceptions of human dignity of the embryo and how it is socially presented within the country’s research culture. [11]

b.     Ubuntu and Collective Cultures

African bioethics differs from Western individualism because of the different traditions and values. African traditions, as described by individuals from South Africa and supported by some studies in other African countries, including Ghana and Kenya, follow the African moral philosophies of Ubuntu or Botho and Ukama , which “advocates for a form of wholeness that comes through one’s relationship and connectedness with other people in the society,” [12] making autonomy a socially collective concept. In this context, for the community to act autonomously, individuals would come together to decide what is best for the collective. Thus, stem cell research would require examining the value of the research to society as a whole and the use of the embryos as a collective societal resource. If society views the source as part of the collective whole, and opposes using stem cells, compromising the cultural values to pursue research may cause social detachment and stunt research growth. [13] Based on local culture and moral philosophy, the permissibility of stem cell research depends on how embryo, stem cell, and cell line therapies relate to the community as a whole. Ubuntu is the expression of humanness, with the person’s identity drawn from the “’I am because we are’” value. [14] The decision in a collectivistic culture becomes one born of cultural context, and individual decisions give deference to others in the society.

Consent differs in cultures where thought and moral philosophy are based on a collective paradigm. So, applying Western bioethical concepts is unrealistic. For one, Africa is a diverse continent with many countries with different belief systems, access to health care, and reliance on traditional or Western medicines. Where traditional medicine is the primary treatment, the “’restrictive focus on biomedically-related bioethics’” [is] problematic in African contexts because it neglects bioethical issues raised by traditional systems.” [15] No single approach applies in all areas or contexts. Rather than evaluating the permissibility of ESC research according to Western concepts such as the four principles approach, different ethics approaches should prevail.

Another consideration is the socio-economic standing of countries. In parts of South Africa, researchers have not focused heavily on contributing to the stem cell discourse, either because it is not considered health care or a health science priority or because resources are unavailable. [16] Each country’s priorities differ given different social, political, and economic factors. In South Africa, for instance, areas such as maternal mortality, non-communicable diseases, telemedicine, and the strength of health systems need improvement and require more focus. [17] Stem cell research could benefit the population, but it also could divert resources from basic medical care. Researchers in South Africa adhere to the National Health Act and Medicines Control Act in South Africa and international guidelines; however, the Act is not strictly enforced, and there is no clear legislation for research conduct or ethical guidelines. [18]

Some parts of Africa condemn stem cell research. For example, 98.2 percent of the Tunisian population is Muslim. [19] Tunisia does not permit stem cell research because of moral conflict with a Fatwa. Religion heavily saturates the regulation and direction of research. [20] Stem cell use became permissible for reproductive purposes only recently, with tight restrictions preventing cells from being used in any research other than procedures concerning ART/IVF.  Their use is conditioned on consent, and available only to married couples. [21] The community's receptiveness to stem cell research depends on including communitarian African ethics.

c.     Asia

Some Asian countries also have a collective model of ethics and decision making. [22] In China, the ethics model promotes a sincere respect for life or human dignity, [23] based on protective medicine. This model, influenced by Traditional Chinese Medicine (TCM), [24] recognizes Qi as the vital energy delivered via the meridians of the body; it connects illness to body systems, the body’s entire constitution, and the universe for a holistic bond of nature, health, and quality of life. [25] Following a protective ethics model, and traditional customs of wholeness, investment in stem cell research is heavily desired for its applications in regenerative therapies, disease modeling, and protective medicines. In a survey of medical students and healthcare practitioners, 30.8 percent considered stem cell research morally unacceptable while 63.5 percent accepted medical research using human embryonic stem cells. Of these individuals, 89.9 percent supported increased funding for stem cell research. [26] The scientific community might not reflect the overall population. From 1997 to 2019, China spent a total of $576 million (USD) on stem cell research at 8,050 stem cell programs, increased published presence from 0.6 percent to 14.01 percent of total global stem cell publications as of 2014, and made significant strides in cell-based therapies for various medical conditions. [27] However, while China has made substantial investments in stem cell research and achieved notable progress in clinical applications, concerns linger regarding ethical oversight and transparency. [28] For example, the China Biosecurity Law, promoted by the National Health Commission and China Hospital Association, attempted to mitigate risks by introducing an institutional review board (IRB) in the regulatory bodies. 5800 IRBs registered with the Chinese Clinical Trial Registry since 2021. [29] However, issues still need to be addressed in implementing effective IRB review and approval procedures.

The substantial government funding and focus on scientific advancement have sometimes overshadowed considerations of regional cultures, ethnic minorities, and individual perspectives, particularly evident during the one-child policy era. As government policy adapts to promote public stability, such as the change from the one-child to the two-child policy, [30] research ethics should also adapt to ensure respect for the values of its represented peoples.

Japan is also relatively supportive of stem cell research and therapies. Japan has a more transparent regulatory framework, allowing for faster approval of regenerative medicine products, which has led to several advanced clinical trials and therapies. [31] South Korea is also actively engaged in stem cell research and has a history of breakthroughs in cloning and embryonic stem cells. [32] However, the field is controversial, and there are issues of scientific integrity. For example, the Korean FDA fast-tracked products for approval, [33] and in another instance, the oocyte source was unclear and possibly violated ethical standards. [34] Trust is important in research, as it builds collaborative foundations between colleagues, trial participant comfort, open-mindedness for complicated and sensitive discussions, and supports regulatory procedures for stakeholders. There is a need to respect the culture’s interest, engagement, and for research and clinical trials to be transparent and have ethical oversight to promote global research discourse and trust.

d.     Middle East

Countries in the Middle East have varying degrees of acceptance of or restrictions to policies related to using embryonic stem cells due to cultural and religious influences. Saudi Arabia has made significant contributions to stem cell research, and conducts research based on international guidelines for ethical conduct and under strict adherence to guidelines in accordance with Islamic principles. Specifically, the Saudi government and people require ESC research to adhere to Sharia law. In addition to umbilical and placental stem cells, [35] Saudi Arabia permits the use of embryonic stem cells as long as they come from miscarriages, therapeutic abortions permissible by Sharia law, or are left over from in vitro fertilization and donated to research. [36] Laws and ethical guidelines for stem cell research allow the development of research institutions such as the King Abdullah International Medical Research Center, which has a cord blood bank and a stem cell registry with nearly 10,000 donors. [37] Such volume and acceptance are due to the ethical ‘permissibility’ of the donor sources, which do not conflict with religious pillars. However, some researchers err on the side of caution, choosing not to use embryos or fetal tissue as they feel it is unethical to do so. [38]

Jordan has a positive research ethics culture. [39] However, there is a significant issue of lack of trust in researchers, with 45.23 percent (38.66 percent agreeing and 6.57 percent strongly agreeing) of Jordanians holding a low level of trust in researchers, compared to 81.34 percent of Jordanians agreeing that they feel safe to participate in a research trial. [40] Safety testifies to the feeling of confidence that adequate measures are in place to protect participants from harm, whereas trust in researchers could represent the confidence in researchers to act in the participants’ best interests, adhere to ethical guidelines, provide accurate information, and respect participants’ rights and dignity. One method to improve trust would be to address communication issues relevant to ESC. Legislation surrounding stem cell research has adopted specific language, especially concerning clarification “between ‘stem cells’ and ‘embryonic stem cells’” in translation. [41] Furthermore, legislation “mandates the creation of a national committee… laying out specific regulations for stem-cell banking in accordance with international standards.” [42] This broad regulation opens the door for future global engagement and maintains transparency. However, these regulations may also constrain the influence of research direction, pace, and accessibility of research outcomes.

e.     Europe

In the European Union (EU), ethics is also principle-based, but the principles of autonomy, dignity, integrity, and vulnerability are interconnected. [43] As such, the opportunity for cohesion and concessions between individuals’ thoughts and ideals allows for a more adaptable ethics model due to the flexible principles that relate to the human experience The EU has put forth a framework in its Convention for the Protection of Human Rights and Dignity of the Human Being allowing member states to take different approaches. Each European state applies these principles to its specific conventions, leading to or reflecting different acceptance levels of stem cell research. [44]

For example, in Germany, Lebenzusammenhang , or the coherence of life, references integrity in the unity of human culture. Namely, the personal sphere “should not be subject to external intervention.” [45]  Stem cell interventions could affect this concept of bodily completeness, leading to heavy restrictions. Under the Grundgesetz, human dignity and the right to life with physical integrity are paramount. [46] The Embryo Protection Act of 1991 made producing cell lines illegal. Cell lines can be imported if approved by the Central Ethics Commission for Stem Cell Research only if they were derived before May 2007. [47] Stem cell research respects the integrity of life for the embryo with heavy specifications and intense oversight. This is vastly different in Finland, where the regulatory bodies find research more permissible in IVF excess, but only up to 14 days after fertilization. [48] Spain’s approach differs still, with a comprehensive regulatory framework. [49] Thus, research regulation can be culture-specific due to variations in applied principles. Diverse cultures call for various approaches to ethical permissibility. [50] Only an adaptive-deliberative model can address the cultural constructions of self and achieve positive, culturally sensitive stem cell research practices. [51]

II.     Religious Perspectives on ESC

Embryonic stem cell sources are the main consideration within religious contexts. While individuals may not regard their own religious texts as authoritative or factual, religion can shape their foundations or perspectives.

The Qur'an states:

“And indeed We created man from a quintessence of clay. Then We placed within him a small quantity of nutfa (sperm to fertilize) in a safe place. Then We have fashioned the nutfa into an ‘alaqa (clinging clot or cell cluster), then We developed the ‘alaqa into mudgha (a lump of flesh), and We made mudgha into bones, and clothed the bones with flesh, then We brought it into being as a new creation. So Blessed is Allah, the Best of Creators.” [52]

Many scholars of Islam estimate the time of soul installment, marked by the angel breathing in the soul to bring the individual into creation, as 120 days from conception. [53] Personhood begins at this point, and the value of life would prohibit research or experimentation that could harm the individual. If the fetus is more than 120 days old, the time ensoulment is interpreted to occur according to Islamic law, abortion is no longer permissible. [54] There are a few opposing opinions about early embryos in Islamic traditions. According to some Islamic theologians, there is no ensoulment of the early embryo, which is the source of stem cells for ESC research. [55]

In Buddhism, the stance on stem cell research is not settled. The main tenets, the prohibition against harming or destroying others (ahimsa) and the pursuit of knowledge (prajña) and compassion (karuna), leave Buddhist scholars and communities divided. [56] Some scholars argue stem cell research is in accordance with the Buddhist tenet of seeking knowledge and ending human suffering. Others feel it violates the principle of not harming others. Finding the balance between these two points relies on the karmic burden of Buddhist morality. In trying to prevent ahimsa towards the embryo, Buddhist scholars suggest that to comply with Buddhist tenets, research cannot be done as the embryo has personhood at the moment of conception and would reincarnate immediately, harming the individual's ability to build their karmic burden. [57] On the other hand, the Bodhisattvas, those considered to be on the path to enlightenment or Nirvana, have given organs and flesh to others to help alleviate grieving and to benefit all. [58] Acceptance varies on applied beliefs and interpretations.

Catholicism does not support embryonic stem cell research, as it entails creation or destruction of human embryos. This destruction conflicts with the belief in the sanctity of life. For example, in the Old Testament, Genesis describes humanity as being created in God’s image and multiplying on the Earth, referencing the sacred rights to human conception and the purpose of development and life. In the Ten Commandments, the tenet that one should not kill has numerous interpretations where killing could mean murder or shedding of the sanctity of life, demonstrating the high value of human personhood. In other books, the theological conception of when life begins is interpreted as in utero, [59] highlighting the inviolability of life and its formation in vivo to make a religious point for accepting such research as relatively limited, if at all. [60] The Vatican has released ethical directives to help apply a theological basis to modern-day conflicts. The Magisterium of the Church states that “unless there is a moral certainty of not causing harm,” experimentation on fetuses, fertilized cells, stem cells, or embryos constitutes a crime. [61] Such procedures would not respect the human person who exists at these stages, according to Catholicism. Damages to the embryo are considered gravely immoral and illicit. [62] Although the Catholic Church officially opposes abortion, surveys demonstrate that many Catholic people hold pro-choice views, whether due to the context of conception, stage of pregnancy, threat to the mother’s life, or for other reasons, demonstrating that practicing members can also accept some but not all tenets. [63]

Some major Jewish denominations, such as the Reform, Conservative, and Reconstructionist movements, are open to supporting ESC use or research as long as it is for saving a life. [64] Within Judaism, the Talmud, or study, gives personhood to the child at birth and emphasizes that life does not begin at conception: [65]

“If she is found pregnant, until the fortieth day it is mere fluid,” [66]

Whereas most religions prioritize the status of human embryos, the Halakah (Jewish religious law) states that to save one life, most other religious laws can be ignored because it is in pursuit of preservation. [67] Stem cell research is accepted due to application of these religious laws.

We recognize that all religions contain subsets and sects. The variety of environmental and cultural differences within religious groups requires further analysis to respect the flexibility of religious thoughts and practices. We make no presumptions that all cultures require notions of autonomy or morality as under the common morality theory , which asserts a set of universal moral norms that all individuals share provides moral reasoning and guides ethical decisions. [68] We only wish to show that the interaction with morality varies between cultures and countries.

III.     A Flexible Ethical Approach

The plurality of different moral approaches described above demonstrates that there can be no universally acceptable uniform law for ESC on a global scale. Instead of developing one standard, flexible ethical applications must be continued. We recommend local guidelines that incorporate important cultural and ethical priorities.

While the Declaration of Helsinki is more relevant to people in clinical trials receiving ESC products, in keeping with the tradition of protections for research subjects, consent of the donor is an ethical requirement for ESC donation in many jurisdictions including the US, Canada, and Europe. [69] The Declaration of Helsinki provides a reference point for regulatory standards and could potentially be used as a universal baseline for obtaining consent prior to gamete or embryo donation.

For instance, in Columbia University’s egg donor program for stem cell research, donors followed standard screening protocols and “underwent counseling sessions that included information as to the purpose of oocyte donation for research, what the oocytes would be used for, the risks and benefits of donation, and process of oocyte stimulation” to ensure transparency for consent. [70] The program helped advance stem cell research and provided clear and safe research methods with paid participants. Though paid participation or covering costs of incidental expenses may not be socially acceptable in every culture or context, [71] and creating embryos for ESC research is illegal in many jurisdictions, Columbia’s program was effective because of the clear and honest communications with donors, IRBs, and related stakeholders.  This example demonstrates that cultural acceptance of scientific research and of the idea that an egg or embryo does not have personhood is likely behind societal acceptance of donating eggs for ESC research. As noted, many countries do not permit the creation of embryos for research.

Proper communication and education regarding the process and purpose of stem cell research may bolster comprehension and garner more acceptance. “Given the sensitive subject material, a complete consent process can support voluntary participation through trust, understanding, and ethical norms from the cultures and morals participants value. This can be hard for researchers entering countries of different socioeconomic stability, with different languages and different societal values. [72]

An adequate moral foundation in medical ethics is derived from the cultural and religious basis that informs knowledge and actions. [73] Understanding local cultural and religious values and their impact on research could help researchers develop humility and promote inclusion.

IV.     Concerns

Some may argue that if researchers all adhere to one ethics standard, protection will be satisfied across all borders, and the global public will trust researchers. However, defining what needs to be protected and how to define such research standards is very specific to the people to which standards are applied. We suggest that applying one uniform guide cannot accurately protect each individual because we all possess our own perceptions and interpretations of social values. [74] Therefore, the issue of not adjusting to the moral pluralism between peoples in applying one standard of ethics can be resolved by building out ethics models that can be adapted to different cultures and religions.

Other concerns include medical tourism, which may promote health inequities. [75] Some countries may develop and approve products derived from ESC research before others, compromising research ethics or drug approval processes. There are also concerns about the sale of unauthorized stem cell treatments, for example, those without FDA approval in the United States. Countries with robust research infrastructures may be tempted to attract medical tourists, and some customers will have false hopes based on aggressive publicity of unproven treatments. [76]

For example, in China, stem cell clinics can market to foreign clients who are not protected under the regulatory regimes. Companies employ a marketing strategy of “ethically friendly” therapies. Specifically, in the case of Beike, China’s leading stem cell tourism company and sprouting network, ethical oversight of administrators or health bureaus at one site has “the unintended consequence of shifting questionable activities to another node in Beike's diffuse network.” [77] In contrast, Jordan is aware of stem cell research’s potential abuse and its own status as a “health-care hub.” Jordan’s expanded regulations include preserving the interests of individuals in clinical trials and banning private companies from ESC research to preserve transparency and the integrity of research practices. [78]

The social priorities of the community are also a concern. The ISSCR explicitly states that guidelines “should be periodically revised to accommodate scientific advances, new challenges, and evolving social priorities.” [79] The adaptable ethics model extends this consideration further by addressing whether research is warranted given the varying degrees of socioeconomic conditions, political stability, and healthcare accessibilities and limitations. An ethical approach would require discussion about resource allocation and appropriate distribution of funds. [80]

While some religions emphasize the sanctity of life from conception, which may lead to public opposition to ESC research, others encourage ESC research due to its potential for healing and alleviating human pain. Many countries have special regulations that balance local views on embryonic personhood, the benefits of research as individual or societal goods, and the protection of human research subjects. To foster understanding and constructive dialogue, global policy frameworks should prioritize the protection of universal human rights, transparency, and informed consent. In addition to these foundational global policies, we recommend tailoring local guidelines to reflect the diverse cultural and religious perspectives of the populations they govern. Ethics models should be adapted to local populations to effectively establish research protections, growth, and possibilities of stem cell research.

For example, in countries with strong beliefs in the moral sanctity of embryos or heavy religious restrictions, an adaptive model can allow for discussion instead of immediate rejection. In countries with limited individual rights and voice in science policy, an adaptive model ensures cultural, moral, and religious views are taken into consideration, thereby building social inclusion. While this ethical consideration by the government may not give a complete voice to every individual, it will help balance policies and maintain the diverse perspectives of those it affects. Embracing an adaptive ethics model of ESC research promotes open-minded dialogue and respect for the importance of human belief and tradition. By actively engaging with cultural and religious values, researchers can better handle disagreements and promote ethical research practices that benefit each society.

This brief exploration of the religious and cultural differences that impact ESC research reveals the nuances of relative ethics and highlights a need for local policymakers to apply a more intense adaptive model.

[1] Poliwoda, S., Noor, N., Downs, E., Schaaf, A., Cantwell, A., Ganti, L., Kaye, A. D., Mosel, L. I., Carroll, C. B., Viswanath, O., & Urits, I. (2022). Stem cells: a comprehensive review of origins and emerging clinical roles in medical practice.  Orthopedic reviews ,  14 (3), 37498. https://doi.org/10.52965/001c.37498

[2] Poliwoda, S., Noor, N., Downs, E., Schaaf, A., Cantwell, A., Ganti, L., Kaye, A. D., Mosel, L. I., Carroll, C. B., Viswanath, O., & Urits, I. (2022). Stem cells: a comprehensive review of origins and emerging clinical roles in medical practice.  Orthopedic reviews ,  14 (3), 37498. https://doi.org/10.52965/001c.37498

[3] International Society for Stem Cell Research. (2023). Laboratory-based human embryonic stem cell research, embryo research, and related research activities . International Society for Stem Cell Research. https://www.isscr.org/guidelines/blog-post-title-one-ed2td-6fcdk ; Kimmelman, J., Hyun, I., Benvenisty, N.  et al.  Policy: Global standards for stem-cell research.  Nature   533 , 311–313 (2016). https://doi.org/10.1038/533311a

[4] International Society for Stem Cell Research. (2023). Laboratory-based human embryonic stem cell research, embryo research, and related research activities . International Society for Stem Cell Research. https://www.isscr.org/guidelines/blog-post-title-one-ed2td-6fcdk

[5] Concerning the moral philosophies of stem cell research, our paper does not posit a personal moral stance nor delve into the “when” of human life begins. To read further about the philosophical debate, consider the following sources:

Sandel M. J. (2004). Embryo ethics--the moral logic of stem-cell research.  The New England journal of medicine ,  351 (3), 207–209. https://doi.org/10.1056/NEJMp048145 ; George, R. P., & Lee, P. (2020, September 26). Acorns and Embryos . The New Atlantis. https://www.thenewatlantis.com/publications/acorns-and-embryos ; Sagan, A., & Singer, P. (2007). The moral status of stem cells. Metaphilosophy , 38 (2/3), 264–284. http://www.jstor.org/stable/24439776 ; McHugh P. R. (2004). Zygote and "clonote"--the ethical use of embryonic stem cells.  The New England journal of medicine ,  351 (3), 209–211. https://doi.org/10.1056/NEJMp048147 ; Kurjak, A., & Tripalo, A. (2004). The facts and doubts about beginning of the human life and personality.  Bosnian journal of basic medical sciences ,  4 (1), 5–14. https://doi.org/10.17305/bjbms.2004.3453

[6] Vazin, T., & Freed, W. J. (2010). Human embryonic stem cells: derivation, culture, and differentiation: a review.  Restorative neurology and neuroscience ,  28 (4), 589–603. https://doi.org/10.3233/RNN-2010-0543

[7] Socially, at its core, the Western approach to ethics is widely principle-based, autonomy being one of the key factors to ensure a fundamental respect for persons within research. For information regarding autonomy in research, see: Department of Health, Education, and Welfare, & National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research (1978). The Belmont Report. Ethical principles and guidelines for the protection of human subjects of research.; For a more in-depth review of autonomy within the US, see: Beauchamp, T. L., & Childress, J. F. (1994). Principles of Biomedical Ethics . Oxford University Press.

[8] Sherley v. Sebelius , 644 F.3d 388 (D.C. Cir. 2011), citing 45 C.F.R. 46.204(b) and [42 U.S.C. § 289g(b)]. https://www.cadc.uscourts.gov/internet/opinions.nsf/6c690438a9b43dd685257a64004ebf99/$file/11-5241-1391178.pdf

[9] Stem Cell Research Enhancement Act of 2005, H. R. 810, 109 th Cong. (2001). https://www.govtrack.us/congress/bills/109/hr810/text ; Bush, G. W. (2006, July 19). Message to the House of Representatives . National Archives and Records Administration. https://georgewbush-whitehouse.archives.gov/news/releases/2006/07/20060719-5.html

[10] National Archives and Records Administration. (2009, March 9). Executive order 13505 -- removing barriers to responsible scientific research involving human stem cells . National Archives and Records Administration. https://obamawhitehouse.archives.gov/the-press-office/removing-barriers-responsible-scientific-research-involving-human-stem-cells

[11] Hurlbut, W. B. (2006). Science, Religion, and the Politics of Stem Cells.  Social Research ,  73 (3), 819–834. http://www.jstor.org/stable/40971854

[12] Akpa-Inyang, Francis & Chima, Sylvester. (2021). South African traditional values and beliefs regarding informed consent and limitations of the principle of respect for autonomy in African communities: a cross-cultural qualitative study. BMC Medical Ethics . 22. 10.1186/s12910-021-00678-4.

[13] Source for further reading: Tangwa G. B. (2007). Moral status of embryonic stem cells: perspective of an African villager. Bioethics , 21(8), 449–457. https://doi.org/10.1111/j.1467-8519.2007.00582.x , see also Mnisi, F. M. (2020). An African analysis based on ethics of Ubuntu - are human embryonic stem cell patents morally justifiable? African Insight , 49 (4).

[14] Jecker, N. S., & Atuire, C. (2021). Bioethics in Africa: A contextually enlightened analysis of three cases. Developing World Bioethics , 22 (2), 112–122. https://doi.org/10.1111/dewb.12324

[15] Jecker, N. S., & Atuire, C. (2021). Bioethics in Africa: A contextually enlightened analysis of three cases. Developing World Bioethics, 22(2), 112–122. https://doi.org/10.1111/dewb.12324

[16] Jackson, C.S., Pepper, M.S. Opportunities and barriers to establishing a cell therapy programme in South Africa.  Stem Cell Res Ther   4 , 54 (2013). https://doi.org/10.1186/scrt204 ; Pew Research Center. (2014, May 1). Public health a major priority in African nations . Pew Research Center’s Global Attitudes Project. https://www.pewresearch.org/global/2014/05/01/public-health-a-major-priority-in-african-nations/

[17] Department of Health Republic of South Africa. (2021). Health Research Priorities (revised) for South Africa 2021-2024 . National Health Research Strategy. https://www.health.gov.za/wp-content/uploads/2022/05/National-Health-Research-Priorities-2021-2024.pdf

[18] Oosthuizen, H. (2013). Legal and Ethical Issues in Stem Cell Research in South Africa. In: Beran, R. (eds) Legal and Forensic Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-32338-6_80 , see also: Gaobotse G (2018) Stem Cell Research in Africa: Legislation and Challenges. J Regen Med 7:1. doi: 10.4172/2325-9620.1000142

[19] United States Bureau of Citizenship and Immigration Services. (1998). Tunisia: Information on the status of Christian conversions in Tunisia . UNHCR Web Archive. https://webarchive.archive.unhcr.org/20230522142618/https://www.refworld.org/docid/3df0be9a2.html

[20] Gaobotse, G. (2018) Stem Cell Research in Africa: Legislation and Challenges. J Regen Med 7:1. doi: 10.4172/2325-9620.1000142

[21] Kooli, C. Review of assisted reproduction techniques, laws, and regulations in Muslim countries.  Middle East Fertil Soc J   24 , 8 (2020). https://doi.org/10.1186/s43043-019-0011-0 ; Gaobotse, G. (2018) Stem Cell Research in Africa: Legislation and Challenges. J Regen Med 7:1. doi: 10.4172/2325-9620.1000142

[22] Pang M. C. (1999). Protective truthfulness: the Chinese way of safeguarding patients in informed treatment decisions. Journal of medical ethics , 25(3), 247–253. https://doi.org/10.1136/jme.25.3.247

[23] Wang, L., Wang, F., & Zhang, W. (2021). Bioethics in China’s biosecurity law: Forms, effects, and unsettled issues. Journal of law and the biosciences , 8(1).  https://doi.org/10.1093/jlb/lsab019 https://academic.oup.com/jlb/article/8/1/lsab019/6299199

[24] Wang, Y., Xue, Y., & Guo, H. D. (2022). Intervention effects of traditional Chinese medicine on stem cell therapy of myocardial infarction.  Frontiers in pharmacology ,  13 , 1013740. https://doi.org/10.3389/fphar.2022.1013740

[25] Li, X.-T., & Zhao, J. (2012). Chapter 4: An Approach to the Nature of Qi in TCM- Qi and Bioenergy. In Recent Advances in Theories and Practice of Chinese Medicine (p. 79). InTech.

[26] Luo, D., Xu, Z., Wang, Z., & Ran, W. (2021). China's Stem Cell Research and Knowledge Levels of Medical Practitioners and Students.  Stem cells international ,  2021 , 6667743. https://doi.org/10.1155/2021/6667743

[27] Luo, D., Xu, Z., Wang, Z., & Ran, W. (2021). China's Stem Cell Research and Knowledge Levels of Medical Practitioners and Students.  Stem cells international ,  2021 , 6667743. https://doi.org/10.1155/2021/6667743

[28] Zhang, J. Y. (2017). Lost in translation? accountability and governance of Clinical Stem Cell Research in China. Regenerative Medicine , 12 (6), 647–656. https://doi.org/10.2217/rme-2017-0035

[29] Wang, L., Wang, F., & Zhang, W. (2021). Bioethics in China’s biosecurity law: Forms, effects, and unsettled issues. Journal of law and the biosciences , 8(1).  https://doi.org/10.1093/jlb/lsab019 https://academic.oup.com/jlb/article/8/1/lsab019/6299199

[30] Chen, H., Wei, T., Wang, H.  et al.  Association of China’s two-child policy with changes in number of births and birth defects rate, 2008–2017.  BMC Public Health   22 , 434 (2022). https://doi.org/10.1186/s12889-022-12839-0

[31] Azuma, K. Regulatory Landscape of Regenerative Medicine in Japan.  Curr Stem Cell Rep   1 , 118–128 (2015). https://doi.org/10.1007/s40778-015-0012-6

[32] Harris, R. (2005, May 19). Researchers Report Advance in Stem Cell Production . NPR. https://www.npr.org/2005/05/19/4658967/researchers-report-advance-in-stem-cell-production

[33] Park, S. (2012). South Korea steps up stem-cell work.  Nature . https://doi.org/10.1038/nature.2012.10565

[34] Resnik, D. B., Shamoo, A. E., & Krimsky, S. (2006). Fraudulent human embryonic stem cell research in South Korea: lessons learned.  Accountability in research ,  13 (1), 101–109. https://doi.org/10.1080/08989620600634193 .

[35] Alahmad, G., Aljohani, S., & Najjar, M. F. (2020). Ethical challenges regarding the use of stem cells: interviews with researchers from Saudi Arabia. BMC medical ethics, 21(1), 35. https://doi.org/10.1186/s12910-020-00482-6

[36] Association for the Advancement of Blood and Biotherapies.  https://www.aabb.org/regulatory-and-advocacy/regulatory-affairs/regulatory-for-cellular-therapies/international-competent-authorities/saudi-arabia

[37] Alahmad, G., Aljohani, S., & Najjar, M. F. (2020). Ethical challenges regarding the use of stem cells: Interviews with researchers from Saudi Arabia.  BMC medical ethics ,  21 (1), 35. https://doi.org/10.1186/s12910-020-00482-6

[38] Alahmad, G., Aljohani, S., & Najjar, M. F. (2020). Ethical challenges regarding the use of stem cells: Interviews with researchers from Saudi Arabia. BMC medical ethics , 21(1), 35. https://doi.org/10.1186/s12910-020-00482-6

Culturally, autonomy practices follow a relational autonomy approach based on a paternalistic deontological health care model. The adherence to strict international research policies and religious pillars within the regulatory environment is a great foundation for research ethics. However, there is a need to develop locally targeted ethics approaches for research (as called for in Alahmad, G., Aljohani, S., & Najjar, M. F. (2020). Ethical challenges regarding the use of stem cells: interviews with researchers from Saudi Arabia. BMC medical ethics, 21(1), 35. https://doi.org/10.1186/s12910-020-00482-6), this decision-making approach may help advise a research decision model. For more on the clinical cultural autonomy approaches, see: Alabdullah, Y. Y., Alzaid, E., Alsaad, S., Alamri, T., Alolayan, S. W., Bah, S., & Aljoudi, A. S. (2022). Autonomy and paternalism in Shared decision‐making in a Saudi Arabian tertiary hospital: A cross‐sectional study. Developing World Bioethics , 23 (3), 260–268. https://doi.org/10.1111/dewb.12355 ; Bukhari, A. A. (2017). Universal Principles of Bioethics and Patient Rights in Saudi Arabia (Doctoral dissertation, Duquesne University). https://dsc.duq.edu/etd/124; Ladha, S., Nakshawani, S. A., Alzaidy, A., & Tarab, B. (2023, October 26). Islam and Bioethics: What We All Need to Know . Columbia University School of Professional Studies. https://sps.columbia.edu/events/islam-and-bioethics-what-we-all-need-know

[39] Ababneh, M. A., Al-Azzam, S. I., Alzoubi, K., Rababa’h, A., & Al Demour, S. (2021). Understanding and attitudes of the Jordanian public about clinical research ethics.  Research Ethics ,  17 (2), 228-241.  https://doi.org/10.1177/1747016120966779

[40] Ababneh, M. A., Al-Azzam, S. I., Alzoubi, K., Rababa’h, A., & Al Demour, S. (2021). Understanding and attitudes of the Jordanian public about clinical research ethics.  Research Ethics ,  17 (2), 228-241.  https://doi.org/10.1177/1747016120966779

[41] Dajani, R. (2014). Jordan’s stem-cell law can guide the Middle East.  Nature  510, 189. https://doi.org/10.1038/510189a

[42] Dajani, R. (2014). Jordan’s stem-cell law can guide the Middle East.  Nature  510, 189. https://doi.org/10.1038/510189a

[43] The EU’s definition of autonomy relates to the capacity for creating ideas, moral insight, decisions, and actions without constraint, personal responsibility, and informed consent. However, the EU views autonomy as not completely able to protect individuals and depends on other principles, such as dignity, which “expresses the intrinsic worth and fundamental equality of all human beings.” Rendtorff, J.D., Kemp, P. (2019). Four Ethical Principles in European Bioethics and Biolaw: Autonomy, Dignity, Integrity and Vulnerability. In: Valdés, E., Lecaros, J. (eds) Biolaw and Policy in the Twenty-First Century. International Library of Ethics, Law, and the New Medicine, vol 78. Springer, Cham. https://doi.org/10.1007/978-3-030-05903-3_3

[44] Council of Europe. Convention for the protection of Human Rights and Dignity of the Human Being with regard to the Application of Biology and Medicine: Convention on Human Rights and Biomedicine (ETS No. 164) https://www.coe.int/en/web/conventions/full-list?module=treaty-detail&treatynum=164 (forbidding the creation of embryos for research purposes only, and suggests embryos in vitro have protections.); Also see Drabiak-Syed B. K. (2013). New President, New Human Embryonic Stem Cell Research Policy: Comparative International Perspectives and Embryonic Stem Cell Research Laws in France.  Biotechnology Law Report ,  32 (6), 349–356. https://doi.org/10.1089/blr.2013.9865

[45] Rendtorff, J.D., Kemp, P. (2019). Four Ethical Principles in European Bioethics and Biolaw: Autonomy, Dignity, Integrity and Vulnerability. In: Valdés, E., Lecaros, J. (eds) Biolaw and Policy in the Twenty-First Century. International Library of Ethics, Law, and the New Medicine, vol 78. Springer, Cham. https://doi.org/10.1007/978-3-030-05903-3_3

[46] Tomuschat, C., Currie, D. P., Kommers, D. P., & Kerr, R. (Trans.). (1949, May 23). Basic law for the Federal Republic of Germany. https://www.btg-bestellservice.de/pdf/80201000.pdf

[47] Regulation of Stem Cell Research in Germany . Eurostemcell. (2017, April 26). https://www.eurostemcell.org/regulation-stem-cell-research-germany

[48] Regulation of Stem Cell Research in Finland . Eurostemcell. (2017, April 26). https://www.eurostemcell.org/regulation-stem-cell-research-finland

[49] Regulation of Stem Cell Research in Spain . Eurostemcell. (2017, April 26). https://www.eurostemcell.org/regulation-stem-cell-research-spain

[50] Some sources to consider regarding ethics models or regulatory oversights of other cultures not covered:

Kara MA. Applicability of the principle of respect for autonomy: the perspective of Turkey. J Med Ethics. 2007 Nov;33(11):627-30. doi: 10.1136/jme.2006.017400. PMID: 17971462; PMCID: PMC2598110.

Ugarte, O. N., & Acioly, M. A. (2014). The principle of autonomy in Brazil: one needs to discuss it ...  Revista do Colegio Brasileiro de Cirurgioes ,  41 (5), 374–377. https://doi.org/10.1590/0100-69912014005013

Bharadwaj, A., & Glasner, P. E. (2012). Local cells, global science: The rise of embryonic stem cell research in India . Routledge.

For further research on specific European countries regarding ethical and regulatory framework, we recommend this database: Regulation of Stem Cell Research in Europe . Eurostemcell. (2017, April 26). https://www.eurostemcell.org/regulation-stem-cell-research-europe   

[51] Klitzman, R. (2006). Complications of culture in obtaining informed consent. The American Journal of Bioethics, 6(1), 20–21. https://doi.org/10.1080/15265160500394671 see also: Ekmekci, P. E., & Arda, B. (2017). Interculturalism and Informed Consent: Respecting Cultural Differences without Breaching Human Rights.  Cultura (Iasi, Romania) ,  14 (2), 159–172.; For why trust is important in research, see also: Gray, B., Hilder, J., Macdonald, L., Tester, R., Dowell, A., & Stubbe, M. (2017). Are research ethics guidelines culturally competent?  Research Ethics ,  13 (1), 23-41.  https://doi.org/10.1177/1747016116650235

[52] The Qur'an  (M. Khattab, Trans.). (1965). Al-Mu’minun, 23: 12-14. https://quran.com/23

[53] Lenfest, Y. (2017, December 8). Islam and the beginning of human life . Bill of Health. https://blog.petrieflom.law.harvard.edu/2017/12/08/islam-and-the-beginning-of-human-life/

[54] Aksoy, S. (2005). Making regulations and drawing up legislation in Islamic countries under conditions of uncertainty, with special reference to embryonic stem cell research. Journal of Medical Ethics , 31: 399-403.; see also: Mahmoud, Azza. "Islamic Bioethics: National Regulations and Guidelines of Human Stem Cell Research in the Muslim World." Master's thesis, Chapman University, 2022. https://doi.org/10.36837/ chapman.000386

[55] Rashid, R. (2022). When does Ensoulment occur in the Human Foetus. Journal of the British Islamic Medical Association , 12 (4). ISSN 2634 8071. https://www.jbima.com/wp-content/uploads/2023/01/2-Ethics-3_-Ensoulment_Rafaqat.pdf.

[56] Sivaraman, M. & Noor, S. (2017). Ethics of embryonic stem cell research according to Buddhist, Hindu, Catholic, and Islamic religions: perspective from Malaysia. Asian Biomedicine,8(1) 43-52.  https://doi.org/10.5372/1905-7415.0801.260

[57] Jafari, M., Elahi, F., Ozyurt, S. & Wrigley, T. (2007). 4. Religious Perspectives on Embryonic Stem Cell Research. In K. Monroe, R. Miller & J. Tobis (Ed.),  Fundamentals of the Stem Cell Debate: The Scientific, Religious, Ethical, and Political Issues  (pp. 79-94). Berkeley: University of California Press.  https://escholarship.org/content/qt9rj0k7s3/qt9rj0k7s3_noSplash_f9aca2e02c3777c7fb76ea768ba458f0.pdf https://doi.org/10.1525/9780520940994-005

[58] Lecso, P. A. (1991). The Bodhisattva Ideal and Organ Transplantation.  Journal of Religion and Health ,  30 (1), 35–41. http://www.jstor.org/stable/27510629 ; Bodhisattva, S. (n.d.). The Key of Becoming a Bodhisattva . A Guide to the Bodhisattva Way of Life. http://www.buddhism.org/Sutras/2/BodhisattvaWay.htm

[59] There is no explicit religious reference to when life begins or how to conduct research that interacts with the concept of life. However, these are relevant verses pertaining to how the fetus is viewed. (( King James Bible . (1999). Oxford University Press. (original work published 1769))

Jerimiah 1: 5 “Before I formed thee in the belly I knew thee; and before thou camest forth out of the womb I sanctified thee…”

In prophet Jerimiah’s insight, God set him apart as a person known before childbirth, a theme carried within the Psalm of David.

Psalm 139: 13-14 “…Thou hast covered me in my mother's womb. I will praise thee; for I am fearfully and wonderfully made…”

These verses demonstrate David’s respect for God as an entity that would know of all man’s thoughts and doings even before birth.

[60] It should be noted that abortion is not supported as well.

[61] The Vatican. (1987, February 22). Instruction on Respect for Human Life in Its Origin and on the Dignity of Procreation Replies to Certain Questions of the Day . Congregation For the Doctrine of the Faith. https://www.vatican.va/roman_curia/congregations/cfaith/documents/rc_con_cfaith_doc_19870222_respect-for-human-life_en.html

[62] The Vatican. (2000, August 25). Declaration On the Production and the Scientific and Therapeutic Use of Human Embryonic Stem Cells . Pontifical Academy for Life. https://www.vatican.va/roman_curia/pontifical_academies/acdlife/documents/rc_pa_acdlife_doc_20000824_cellule-staminali_en.html ; Ohara, N. (2003). Ethical Consideration of Experimentation Using Living Human Embryos: The Catholic Church’s Position on Human Embryonic Stem Cell Research and Human Cloning. Department of Obstetrics and Gynecology . Retrieved from https://article.imrpress.com/journal/CEOG/30/2-3/pii/2003018/77-81.pdf.

[63] Smith, G. A. (2022, May 23). Like Americans overall, Catholics vary in their abortion views, with regular mass attenders most opposed . Pew Research Center. https://www.pewresearch.org/short-reads/2022/05/23/like-americans-overall-catholics-vary-in-their-abortion-views-with-regular-mass-attenders-most-opposed/

[64] Rosner, F., & Reichman, E. (2002). Embryonic stem cell research in Jewish law. Journal of halacha and contemporary society , (43), 49–68.; Jafari, M., Elahi, F., Ozyurt, S. & Wrigley, T. (2007). 4. Religious Perspectives on Embryonic Stem Cell Research. In K. Monroe, R. Miller & J. Tobis (Ed.),  Fundamentals of the Stem Cell Debate: The Scientific, Religious, Ethical, and Political Issues  (pp. 79-94). Berkeley: University of California Press.  https://escholarship.org/content/qt9rj0k7s3/qt9rj0k7s3_noSplash_f9aca2e02c3777c7fb76ea768ba458f0.pdf https://doi.org/10.1525/9780520940994-005

[65] Schenker J. G. (2008). The beginning of human life: status of embryo. Perspectives in Halakha (Jewish Religious Law).  Journal of assisted reproduction and genetics ,  25 (6), 271–276. https://doi.org/10.1007/s10815-008-9221-6

[66] Ruttenberg, D. (2020, May 5). The Torah of Abortion Justice (annotated source sheet) . Sefaria. https://www.sefaria.org/sheets/234926.7?lang=bi&with=all&lang2=en

[67] Jafari, M., Elahi, F., Ozyurt, S. & Wrigley, T. (2007). 4. Religious Perspectives on Embryonic Stem Cell Research. In K. Monroe, R. Miller & J. Tobis (Ed.),  Fundamentals of the Stem Cell Debate: The Scientific, Religious, Ethical, and Political Issues  (pp. 79-94). Berkeley: University of California Press.  https://escholarship.org/content/qt9rj0k7s3/qt9rj0k7s3_noSplash_f9aca2e02c3777c7fb76ea768ba458f0.pdf https://doi.org/10.1525/9780520940994-005

[68] Gert, B. (2007). Common morality: Deciding what to do . Oxford Univ. Press.

[69] World Medical Association (2013). World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA , 310(20), 2191–2194. https://doi.org/10.1001/jama.2013.281053 Declaration of Helsinki – WMA – The World Medical Association .; see also: National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. (1979).  The Belmont report: Ethical principles and guidelines for the protection of human subjects of research . U.S. Department of Health and Human Services.  https://www.hhs.gov/ohrp/regulations-and-policy/belmont-report/read-the-belmont-report/index.html

[70] Zakarin Safier, L., Gumer, A., Kline, M., Egli, D., & Sauer, M. V. (2018). Compensating human subjects providing oocytes for stem cell research: 9-year experience and outcomes.  Journal of assisted reproduction and genetics ,  35 (7), 1219–1225. https://doi.org/10.1007/s10815-018-1171-z https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063839/ see also: Riordan, N. H., & Paz Rodríguez, J. (2021). Addressing concerns regarding associated costs, transparency, and integrity of research in recent stem cell trial. Stem Cells Translational Medicine , 10 (12), 1715–1716. https://doi.org/10.1002/sctm.21-0234

[71] Klitzman, R., & Sauer, M. V. (2009). Payment of egg donors in stem cell research in the USA.  Reproductive biomedicine online ,  18 (5), 603–608. https://doi.org/10.1016/s1472-6483(10)60002-8

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[75] Pirzada, N. (2022). The Expansion of Turkey’s Medical Tourism Industry.  Voices in Bioethics ,  8 . https://doi.org/10.52214/vib.v8i.9894

[76] Stem Cell Tourism: False Hope for Real Money . Harvard Stem Cell Institute (HSCI). (2023). https://hsci.harvard.edu/stem-cell-tourism , See also: Bissassar, M. (2017). Transnational Stem Cell Tourism: An ethical analysis.  Voices in Bioethics ,  3 . https://doi.org/10.7916/vib.v3i.6027

[77] Song, P. (2011) The proliferation of stem cell therapies in post-Mao China: problematizing ethical regulation,  New Genetics and Society , 30:2, 141-153, DOI:  10.1080/14636778.2011.574375

[78] Dajani, R. (2014). Jordan’s stem-cell law can guide the Middle East.  Nature  510, 189. https://doi.org/10.1038/510189a

[79] International Society for Stem Cell Research. (2024). Standards in stem cell research . International Society for Stem Cell Research. https://www.isscr.org/guidelines/5-standards-in-stem-cell-research

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Mifrah Hayath

SM Candidate Harvard Medical School, MS Biotechnology Johns Hopkins University

Olivia Bowers

MS Bioethics Columbia University (Disclosure: affiliated with Voices in Bioethics)

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Post-Construction Evaluation Practices for Highway Projects Delivered Using Alternative Contracting Methods

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Post-Construction Evaluation Practices for Highway Projects Delivered Using Alternative Contracting Methods

Alternative contracting methods (ACMs) capture the delivery methods that are not design-bid-build (D-B-B), low bid, or traditional federal aid. Common ACMs used by state departments of transportation (DOTs) include design-build (D-B), construction manager/general contractor (CM/GC), progressive design-build (P-D-B), public-private partnerships (P3), and indefinite delivery/indefinite quantity (IDIQ), which is also called job order contracting.

NCHRP Synthesis 622: Post-Construction Evaluation Practices for Highway Projects Delivered Using Alternative Contracting Methods , from TRB's National Cooperative Highway Research Program, investigates and documents DOT practices for evaluating the outcomes of the ACM processes after project completion.

  • Transportation and Infrastructure — Administration and Management
  • Transportation and Infrastructure — Construction
  • Transportation and Infrastructure — Highways

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National Research Council. 2024. Post-Construction Evaluation Practices for Highway Projects Delivered Using Alternative Contracting Methods . Washington, DC: The National Academies Press. https://doi.org/10.17226/27817. Import this citation to: Bibtex EndNote Reference Manager

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Climate monitoring with citizen science

I-CHANGE actively involves citizens in environmental science, demystifying the field and making it accessible to the wider community. This strategy boosts environmental awareness and fosters sustainable lifestyles and consumption habits.

The recent Genoa Living Lab demonstrates how citizen science can engage the public in environmental monitoring, cultivating a community focused on sustainability.

About I-CHANGE

I-CHANGE is a citizen science initiative that addresses environmental and climate challenges by engaging communities in active environmental monitoring. The project equips citizens with tools, sensors, and knowledge, to involve them in collecting and analysing data to assess the impact of personal and community choices on the environment. Operating through eight Living Labs, including the Genoa Living Lab, I-CHANGE uses a participatory approach, encouraging hands-on participation and developing a deeper understanding of environmental issues.

The project's core lies in empowering individuals and groups to make informed decisions that reduce their environmental footprint, contributing to climate adaptation and mitigation. By involving citizens in the scientific process, I-CHANGE demystifies environmental science, making it accessible to and actionable for the broader community. This approach enhances environmental awareness, while also promoting sustainable lifestyle changes and consumption patterns.

Description of success

The I-CHANGE project has achieved remarkable success through its innovative use of multiple devices for citizen science monitoring, particularly evidenced in the Genoa Living Lab. By using a variety of sensors, such as the MeteoTracker (mobile weather station), the Smart Citizen Science Kit air quality sensor, and on-site weather stations, I-CHANGE addresses various climate-related hazards in a user-friendly manner. This strategic deployment of technology enables the project to connect knowledge about hazards with potential impacts.  As a result, it offers actionable insights and recommendations for citizens to effectively mitigate or adapt to potentially hazardous conditions.

A compelling example of this was demonstrated in Genoa during a week in late August 2023, where a sophisticated interaction between sensors provided a comprehensive understanding of the local urban climate. The MeteoTracker sensor, mounted on a motorbike, revealed significant urban heat island effects with perilously high humidex levels (perceived temperature taking into account the humidity), which highlighted the acute challenges posed by heatwaves. Just days later, the same city centre experienced a severe flash flood event, captured by the on-site weather station, which recorded an extraordinarily high rainfall, underscoring the project's vital role in real-time environmental monitoring and hazard assessment.

I-CHANGE charts

  • The use of various sensors like the MeteoTracker and the Smart Citizen Science Kit air quality sensor across eight Living Labs, particularly in Genoa, showcases I-CHANGE's innovative approach to environmental monitoring.
  • The project's ability to capture and analyse different climate-related hazards in real-time provides valuable insights into phenomena such as urban heat islands, flash floods, and air quality issues.
  • I-CHANGE's participatory approach has successfully engaged citizens in the scientific process, empowering them with the knowledge and tools to actively monitor their environment and make informed decisions.
  • The creation of long-lasting Sustainability Competence Teams (SCTs) and Committees (SCCs) within the Living Labs, ensured sustained community engagement and action towards environmental monitoring and sustainability.
  • The project's success in Genoa has inspired educational ventures, such as a laboratory activity at the Festival of Science 2023, further extending its reach and impact by engaging a broader audience in climate science and sustainability issues.

Thanks to the success of citizen scientists collecting meteorological and climatological data alongside their day-to-day activities, I-CHANGE was inspired to host a Living Laboratory at the Genoa Science Festival 2023. They worked with attendees, sharing ideas on how data could be collected. They also set up their Zero Emission City game where players aim to reduce the carbon footprint of their citizens.

The I-CHANGE project has significantly increased community involvement in environmental monitoring in Genoa, showcasing the effectiveness of citizen science. By providing a variety of sensors to citizens, the project has enabled detailed observation of climate-related events, such as heatwaves and flash floods. This direct involvement has increased environmental awareness and encouraged the community to engage in sustainable practices. I-CHANGE has thus demonstrated a practical model for using citizen science to enhance environmental monitoring and community action towards climate adaptation and mitigation goals.

The Living Labs, which are part of the meteorological toolkit, raised environmental awareness amongst citizens, as well as their understanding of climate science and the effects of climate change. Engaging people directly through their involvement in collecting data enhances their understanding and encourages them to adjust their lifestyle to make more sustainable choices. However, the activities are hands-on and require a lot of time to be successful. There is a risk that some citizen scientists may become disengaged throughout the timeline of the Living Lab. That being said, the successes experienced by the I-CHANGE project in Genoa demonstrate the potential citizen data collection has to play a role in involving the community in climate monitoring.

Other information

Going forward, I-CHANGE will continue their important monitoring work and maintain their citizen science sensor network. You can keep up to date with their real-time MeteoTracker data and weather stations online, as well as follow the progress of their Smart Citizen Kit .

I-CHANGE zero emissions city photo

Project details

Download a pdf of this success story.

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medRxiv

Neurobiology-based Cognitive Biotypes Using Multi-scale Intrinsic Connectivity Networks in Psychotic Disorders

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Objective Understanding the neurobiology of cognitive dysfunction in psychotic disorders remains elusive, as does developing effective interventions. Limited knowledge about the biological heterogeneity of cognitive dysfunction hinders progress. This study aimed to identify subgroups of patients with psychosis with distinct patterns of functional brain alterations related to cognition (cognitive biotypes).

Methods B-SNIP consortium data (2,270 participants including participants with psychotic disorders, relatives, and controls) was analyzed. Researchers used reference-informed independent component analysis and the NeuroMark 100k multi-scale intrinsic connectivity networks (ICN) template to obtain subject-specific ICNs and whole-brain functional network connectivity (FNC). FNC features associated with cognitive performance were identified through multivariate joint analysis. K-means clustering identified subgroups of patients based on these features in a discovery set. Subgroups were further evaluated in a replication set and in relatives.

Results Two biotypes with different functional brain alteration patterns were identified. Biotype 1 exhibited brain-wide alterations, involving hypoconnectivity in cerebellar-subcortical and somatomotor-visual networks and worse cognitive performance. Biotype 2 exhibited hyperconnectivity in somatomotor-subcortical networks and hypoconnectivity in somatomotor-high cognitive processing networks, and better preserved cognitive performance. Demographic, clinical, cognitive, and FNC characteristics of biotypes were consistent in discovery and replication sets, and in relatives. 70.12% of relatives belonged to the same biotype as their affected family members.

Conclusions These findings suggest two distinctive psychosis-related cognitive biotypes with differing functional brain patterns shared with their relatives. Patient stratification based on these biotypes instead of traditional diagnosis may help to optimize future research and clinical trials addressing cognitive dysfunction in psychotic disorders.

Competing Interest Statement

PAC has received travel support from Neuraxpharm and ROVI. CDC has received honoraria or travel support from Angelini and Janssen. JC, RB, VC, and AI report no financial relationships with commercial interests.

Funding Statement

PAC has received grant support from Programa Intramural de Impulso a la I+D+i 2023 (Instituto de Investigacion Sanitaria Gregorio Maranon). CDC has received grant support from Instituto de Salud Carlos III, Spanish Ministry of Science and Innovation (PI20/00721, JR19/00024) and the European Commission (grant 101057182, project Youth-GEMs). VC has received grant support from the National Institutes of Health (R01MH123610). AI has received grant support from the National Institutes of Health (R01MH123610).

Author Declarations

I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

The details of the IRB/oversight body that provided approval or exemption for the research described are given below:

The storage and management of the data and access procedures are overseen by the National Institute of Mental Health (NIMH) through the National Data Archive (NDA). The Institutional Review Board approved the project at each participating institution: Athens, GA (University of Georgia, B-SNIP2 only); Baltimore, MD (University of Maryland School of Medicine, B-SNIP1 only); Boston, MA (Harvard Medical School), Chicago IL (University of Illinois-Chicago for B-SNIP1 and University of Chicago for B-SNIP2); Dallas, TX (University of Texas Southwestern Medical Center), Detroit MI (Wayne State University, B-SNIP1 only); and Hartford, CT (Yale University School of Medicine).

I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals.

I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).

I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable.

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The storage and management of the data and access procedures are overseen by the National Institute of Mental Health (NIMH) through the National Data Archive (NDA).

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China’s Approach to Foreign Policy Gets Largely Negative Reviews in 24-Country Survey

Still, views of china – and its soft power – are more positive in middle-income countries, table of contents.

  • Road map to the report
  • How views of China have changed in recent years
  • Views of China by age group
  • How views of China’s international behavior have changed over time
  • Most say China does not contribute to world peace and stability
  • China seen as interventionist
  • How opinions about which country is the world’s top economy have changed in recent years
  • Many who see China as the world’s leading economic power also see it as a good thing
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  • How views of Chinese soft power vary by age
  • Views of Chinese technology
  • How confidence in Xi has changed over time
  • How confidence in Xi varies by age
  • Acknowledgments
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research and methodology project pdf

This Pew Research Center analysis focuses on public opinion of China and President Xi Jinping in 24 countries in North America, Europe, the Middle East, the Asia-Pacific region, sub-Saharan Africa and Latin America. The report explores views of China’s role in the world, including as an economic power, and perceptions of Chinese soft power. This is the first year since 2019 that the Global Attitudes Survey has included countries from Africa and Latin America, which were not included more recently due to the coronavirus outbreak .

For non-U.S. data, this report draws on nationally representative surveys of 27,285 adults conducted from Feb. 20 to May 22, 2023. All surveys were conducted over the phone with adults in Canada, France, Germany, Greece, Italy, Japan, Netherlands, South Korea, Spain, Sweden and the United Kingdom. Surveys were conducted face to face in Argentina, Brazil, Hungary, India, Indonesia, Israel, Kenya, Mexico, Nigeria, Poland and South Africa. In Australia, we used a mixed-mode probability-based online panel.

In the United States, we surveyed 3,576 U.S. adults from March 20 to 26, 2023. Everyone who took part in this survey is a member of the Center’s American Trends Panel (ATP), an online survey panel that is recruited through national, random sampling of residential addresses. This way nearly all U.S. adults have a chance of selection. The survey is weighted to be representative of the U.S. adult population by gender, race, ethnicity, partisan affiliation, education and other categories. Read more about the ATP’s methodology .

Here are the questions used for the report , along with responses, and the survey methodology .

Views of China and its international behavior are largely negative

Views of China are broadly negative across 24 countries in a new Pew Research Center survey: A median of 67% of adults express unfavorable views of the country, while 28% have a favorable opinion.

Negative views extend to evaluations of China’s international actions. Despite several high-profile diplomatic initiatives by Beijing over the past year – such as brokering a peace deal between Saudi Arabia and Iran and issuing a 12-point proposal for the end of violence in Ukraine – a median of 71% think China does not contribute to global peace and stability.

Most people also think China does not take into account the interests of other countries in its foreign policy (76%) and a median of 57% say China interferes in the affairs of other nations a great deal or fair amount.

Still, attitudes toward China are somewhat rosier in middle-income than high-income countries. Across eight middle-income countries – places Pew Research Center has not surveyed since 2019 due to the challenges of conducting face-to-face interviews during the pandemic – India stands out as the only middle-income country in which a majority has unfavorable views of China. And in three middle-income countries – Kenya, Mexico and Nigeria – a majority even gives China a positive rating.

Unfavorable views of China widespread

Fewer in these middle-income countries also criticize China’s global behavior, and many more see China’s “soft power” appeal. Indeed, publics in these middle-income countries offer relatively favorable ratings for China’s entertainment products, its universities and its standard of living – while few in most high-income countries agree.

Across all 24 countries surveyed, however, there is more agreement about China’s technology. A median of 69% describe China’s technological achievements as the best or above average relative to other wealthy nations, with similar shares in high- and middle-income countries. A median of 54% also see China’s military as among the best in the world.

But views of the country as the world’s foremost economic power have faltered somewhat in recent years. More people now name the United States as the top economic power than China (a median of 42% vs. 33%, respectively). Much of this shift has come in high-income countries, where the share naming China has fallen in nearly every surveyed country – including by double digits in Germany, the Netherlands, Poland and Sweden.

In the U.S., where equal shares (43%) called China and the U.S. the world’s leading economic power in 2022, views have shifted significantly over the past year ; now, Americans are 10 percentage points more likely to name the U.S. than China (48% vs. 38%). (For more on American views of China, read “ Americans are Critical of China’s Global Role – as Well as Its Relationship With Russia ”.)

These findings come from a new Pew Research Center survey conducted from Feb. 20 to May 22, 2023, among more than 30,000 people in 24 countries. Below are some of the other findings regarding China’s overall image, views of Chinese foreign policy, ratings of President Xi Jinping, opinions about Chinese soft power and its economic power.

Overall ratings for China

Across many high-income countries surveyed, which are in North America, Western Europe and parts of the Asia-Pacific region, a large majority has unfavorable views of China, as has been the case for multiple years . Indeed, in almost every high-income country surveyed, negative views currently stand at or near historic highs. In most countries, this does not reflect a significant increase over last year; rather, negative views have simply remained high in recent years. One notable exception is Poland, where negative views have increased 12 points during a period of strained bilateral relations , perhaps related to China’s handling of the war in Ukraine.

Record high negative ratings for China in most countries surveyed

Views of China in middle-income countries are relatively more positive. Still, negative ratings in most of these countries have also grown since the countries were last surveyed, pre-pandemic. In South Africa and Mexico, for example, opinions have turned somewhat more negative since 2019, and in Argentina, Brazil and India, negative views have even reached historic highs. In India, military conflicts along a contested border may have contributed to the 21 percentage point increase in unfavorable opinion.

China’s role on the world stage

Majorities in most countries do not think China takes into account the interests of countries like theirs. In Canada, France, Israel, Spain and Sweden, around half or more say China doesn’t consider them at all . Only in the three sub-Saharan African countries surveyed, as well as in Indonesia, does around half or more of the public feel like China listens to their country.

A median of 71% also think China does little or nothing at all to contribute to global peace and stability, compared with a median of 23% who say it is doing a great deal or a fair amount. Australians, Canadians, Indians, Israelis and South Koreans are particularly likely to say China is doing nothing at all to help with global peace and stability.

Most also see China as an interventionist power. A median of 57% say China does interfere a great deal or a fair amount in the affairs of other countries, while a median of 35% say it does not do so much or at all. Around seven-in-ten or more in Australia, Canada, Japan, South Korea, Spain and the U.S. see China getting involved in the affairs of other countries – and many of these places also stood out for the high share who said China’s involvement in domestic politics in their own country was a very serious problem in a 2022 Pew Research Center survey .

But the country which is most likely to see China interfering in the affairs of other countries in this year’s survey is Italy (82%). Italy, which was the only G7 country to join China’s Belt and Road Initiative (BRI) , was debating leaving the initiative at the time that the survey was conducted, but treading delicately for fear of stoking possible Chinese retribution against Italian businesses.

Attitudes toward Xi

Few in the 24 countries surveyed have confidence in Chinese President Xi Jinping to do the right thing regarding world affairs. Across most of Western Europe, the U.S., Canada and much of the Asia-Pacific region, around half in each country say they have no confidence in him at all . Indonesia, Kenya, Nigeria and South Africa stand out as the only countries where a majority or plurality have confidence in his leadership.

Confidence in Xi is closely related to views of China more broadly. In each country surveyed people with unfavorable views of China are more likely to have little confidence in the Chinese president, and vice versa.

Countries with more negative views of China also have less confidence in Xi

Chinese soft power

A bar chart showing China’s technological advancements are seen as the best or above average compared with other wealthy nations, followed by military power

When it comes to elements often considered part of a country’s “soft power,” China’s technological achievements receive high marks, though fewer say the same about its universities, entertainment products or standard of living.

In fact, outside of South Korea, nearly half or more in every country say Chinese technological advancements are the best in the world or above average relative to other wealthy nations. And in many of the middle-income countries, around four-in-ten call Chinese technology the best in the world.

Middle-income countries – many of which are increasingly reliant on Chinese companies like Huawei for components of their 4G and 5G systems – were also asked specifically about technology such as phones, tablets or computers made by Chinese companies. Across these eight countries, there is a relatively widespread sense that these products are well-made. Middle-income publics are more divided when it comes to their cost: A median of 50% describe them as inexpensive, while 44% call them costly.

They are also somewhat divided when it comes to whether technological products made by Chinese companies protect people’s personal data (a median of 45%) or make their data unsafe (40%). (Americans were asked a different but related question about Chinese social media companies; large majorities have little confidence that they will use personal information responsibly or follow privacy policies.)

In every country, at least a plurality – and often a majority – also see China’s “hard power,” its military, as one of the best in the world or above average.

Chinese economic power

Fewer name China as the world’s leading economic power than the U.S. (a median of 33% vs. 42%). And, in many countries, the share naming China as the world’s leading economy has gone down in recent years.

Fewer now call China the world’s top economic power in many places

Interestingly, China’s image as an economic superpower is stronger in high-income countries than middle-income ones. Italy, for example, is the only country where a majority (55%) calls China the leading economic power.

Still, people in middle-income countries do recognize economic benefits from their relations with China. A different survey question, asked only in these countries, finds that around half or more in six middle-income countries say their nation’s economy has benefited a great deal or a fair amount from Chinese investment. In Nigeria, Kenya and South Africa, around seven-in-ten or more say this.

In the U.S., Americans were also asked to name the country which poses the top threat to the U.S. Not only was China the top answer, by far, but Americans see it as both an economic and a national security threat – in sharp contrast to Russia, which is primarily seen as a security threat. To read more about this related analysis, see “ Americans name China as the top threat facing the U.S. ”

The chapters that follow discuss these findings and others in more detail:

  • Chapter 1 looks at overall opinion of China across the countries surveyed, including how perceptions have shifted over the years
  • Chapter 2 considers the negative and positive roles China plays in international affairs
  • Chapter 3 reviews global public opinion about which country is the world’s leading economic power
  • Chapter 4 explores perceptions of Chinese soft power, summarizing how people across 24 countries rate China compared with other wealthy nations
  • Chapter 5 examines confidence in Chinese President Xi Jinping to do the right thing in world affairs

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Americans Remain Critical of China

How people in hong kong view mainland china and their own identity, in east asia, many people see china’s power and influence as a major threat, u.s.-germany relationship remains solid, but underlying policy differences begin to show, how views of the u.s., china and their leaders have changed over time, most popular, report materials.

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ABOUT PEW RESEARCH CENTER  Pew Research Center is a nonpartisan fact tank that informs the public about the issues, attitudes and trends shaping the world. It conducts public opinion polling, demographic research, media content analysis and other empirical social science research. Pew Research Center does not take policy positions. It is a subsidiary of  The Pew Charitable Trusts .

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  7. PDF CHAPTER 1 The Selection of a Research Approach

    research approaches, research designs, and research methods are four key terms representing a perspective about research flow from broad constructions of research to the narrow procedures of methods. Table 1.1 explains these key terms in more detail. Table 1.1 Key Terms and Their Definitions as Used in This Chapter Key Terms

  8. PDF Research Design and Research Methods

    Research Design and Research Methods CHAPTER 3 This chapter uses an emphasis on research design to discuss qualitative, quantitative, and mixed methods research as three major approaches to research in the social sciences. The first major section considers the role of research methods in each of these approaches. This discussion then

  9. (PDF) Uwe Flick, Introducing Research Methodology. A Beginner's Guide

    A Beginner's Guide to Doing a Research Project, Sage Publications, 2011, 296 p. Book review As the title suggests, Flick's book provides the reader an introduction to research methodology, presenting in a friendly manner the approach that young researchers must follow for the implementation of their social research projects.

  10. PDF Research Methodology and Methods

    A research methodology is 'a general approach to studying research topics' (Hussey and Hussey, 1997: 56), which is distinct from a research method. A research method is a tool or a technique that is used to gather data (Bailey, 1994). In contrast, a research methodology determines the important rela-tionship between theory and method.

  11. (PDF) Your research project: a step-by-step guide for the first-time

    The target audience for this book includes those are going to start research as graduate students, junior researchers, and professors teaching courses on research methods. The book entitled "A guide to Research Methodology for Beginners" is succinct and compact by design focusing only on essential concepts rather than burden students with a ...

  12. PDF Portal of Research Methods and Methodologies for Research Projects and

    A main categorization of a research project and degree projects is to decide methodologies to apply to the research project. The methodologies are the processes, followed during the entire research activity. These are used as guidelines to carry out the research project. Quantitative methodology and

  13. (PDF) Research Methodology in Business: A Starter's Guide

    this paper is to provide new researchers with a comprehensive overview of the main. elements of research methodology, particularly in the business domain. After a brief. introduction, the paper ...

  14. PDF Research Methodology: Tools and Techniques

    (iv) Research is based upon observable experience or empirical evidences. (v) Research demands accurate observation and description. (vi) Research involves gathering new data from primary or first-hand sources or using existing data for a new purpose. (vii) Research is characterized by carefully designed procedures that

  15. PDF Research Models and Methodologies

    Definition of Research Research Paradigms (a.k.a research philosophy or research model) specifying concepts-phenomena of interest as defined in model, and statements- propositions involving concepts Theories, Methods and Application Domains Classes of Research Methodologies that have emerged as a consequence of conducting similar kinds of ...

  16. What Is a Research Design

    Step 1: Consider your aims and approach. Step 2: Choose a type of research design. Step 3: Identify your population and sampling method. Step 4: Choose your data collection methods. Step 5: Plan your data collection procedures. Step 6: Decide on your data analysis strategies. Other interesting articles.

  17. PDF CHAPTER 3 PROJECT METHODOLOGY 3.1 Introduction

    PROJECT METHODOLOGY 3.1 Introduction This chapter will cover the details explanation of methodology that is being used to make this project complete and working well. Many methodology or findings from this ... Transmitter in the Internet and do some research about the project related. Once I got the project manual, I tried to find out the ...

  18. PDF Chapter 1. What are Research Methods?

    Try This: Preview Your Awareness of Research Methods (15 minutes) Think about the ways you've used different methods to solve problems and answer questions in your life, then begin to apply those experiences to your understanding of research methods: 1. Make brief lists of ways/tools/methods you know of (or make up a method—be creative!) to a.

  19. Research Methodology Example (PDF + Template)

    Research Methodology Example. Detailed Walkthrough + Free Methodology Chapter Template. If you're working on a dissertation or thesis and are looking for an example of a research methodology chapter, you've come to the right place. In this video, we walk you through a research methodology from a dissertation that earned full distinction ...

  20. PDF Research Methodology: An Introduction Meaning Of Research

    research methods. Since the object of research, particularly the applied research, it to arrive at a solution for a given problem, the available data and the unknown aspects of the problem have to be related to each other to make a solution possible. Keeping this in view, research methods can be put into the following three groups: 1.

  21. Cultural Relativity and Acceptance of Embryonic Stem Cell Research

    Voices in Bioethics is currently seeking submissions on philosophical and practical topics, both current and timeless. Papers addressing access to healthcare, the bioethical implications of recent Supreme Court rulings, environmental ethics, data privacy, cybersecurity, law and bioethics, economics and bioethics, reproductive ethics, research ethics, and pediatric bioethics are sought.

  22. Post-Construction Evaluation Practices for Highway Projects Delivered

    Post-Construction Evaluation Practices for Highway Projects Delivered Using Alternative Contracting Methods Buy from TRB.org Contributor(s): Christofer M. Harper, Daniel Tran, Roy E. Sturgill, Jr.; National Cooperative Highway Research Program; Transportation Research Board; National Academies of Sciences, Engineering, and Medicine

  23. (PDF) Research Methodology (Methods, Approaches And Techniques)

    Abstract. Research is driven by a desire to solve real-world problems. All studies are conducted with some real-world application in mind. While pure theoretical knowledge is the goal of business ...

  24. PDF Methodology

    Methodology Overview The American Trends Panel (ATP), created by Pew Research Center, is a nationally representative ... The questionnaire was developed by Pew Research Center in consultation with Ipsos. The web program was rigorously tested on both PC and mobile devices by the Ipsos project management team and Pew Research Center researchers ...

  25. Empowering sustainable energy practices

    About AURORAThe AURORA project harnesses the collective power of technology and community engagement to address climate change and promote sustainable energy use. With two pivotal initiatives (the AURORA Energy Tracker App and the Aarhus Energy Community), AURORA is setting new standards in environmental stewardship and citizen science.

  26. Climate monitoring with citizen science

    10 May 2024. About I-CHANGE. I-CHANGE is a citizen science initiative that addresses environmental and climate challenges by engaging communities in active environmental monitoring. The project equips citizens with tools, sensors, and knowledge, to involve them in collecting and analysing data to assess the impact of personal and community ...

  27. In Silico Prediction of Skin Sensitization for Compounds via Flexible

    Skin sensitization is increasingly becoming a significant concern in the development of drugs and cosmetics due to consumer safety and occupational health problems. In silico methods have emerged as alternatives to traditional in vivo animal testing due to ethical and economic considerations. In this study, machine learning methods were used to build quantitative structure-activity ...

  28. Neurobiology-based Cognitive Biotypes Using Multi-scale Intrinsic

    Objective: Understanding the neurobiology of cognitive dysfunction in psychotic disorders remains elusive, as does developing effective interventions. Limited knowledge about the biological heterogeneity of cognitive dysfunction hinders progress. This study aimed to identify subgroups of patients with psychosis with distinct patterns of functional brain alterations related to cognition ...

  29. (PDF) Research Design and Methodology

    Adopting a positivist research philosophy and a quantitative approach, the research employs a deductive methodology with data collected via self-reporting questionnaires from 179 teaching staff ...

  30. China's Approach to Foreign Policy Gets Largely ...

    This way nearly all U.S. adults have a chance of selection. The survey is weighted to be representative of the U.S. adult population by gender, race, ethnicity, partisan affiliation, education and other categories. Read more about the ATP's methodology. Here are the questions used for the report, along with responses, and the survey methodology.