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Theses, Dissertations and Projects - Periodontics

Theses/dissertations from 2022 2022.

A Study in Fresh Human Cadaver Heads Examining the Incidence of Maxillary Sinus Membrane Perforation During Crestal Sinus Elevation Comparing Osteotomes to Osseodensification Drills. , Thaer Alqadoumi

Titanium Particles within Mucosa during Non-Surgical Implant Debridement , Holvin Louie

Accuracy of Implant Placement Comparing a Tissue Level Static Guide vs. Dynamic Navigation Using the X-Mark Protocol on Edentulous Mandibles: A Laboratory Study , Nicholas Poovey

Theses/Dissertations from 2020 2020

A Comparison of Heat Generated Between Carbide and Diamond Bur during Implantoplasty , Bryce Chun

Comparison of Heat Generated During Twist Drilling Protocol by Guided and Non-Guided Implant Surgery , Joshua Lee

Theses/Dissertations from 2019 2019

Comparison of antimicrobial agents Ozonated Olive Oil and Chlorhexidine Gluconate - an in vitro study , Amelia David

Accuracy of Intraoral Scanners with Different Total Occlusal Convergence Angles: An In-Vitro Study , Brittany M. Pang

Theses/Dissertations from 2018 2018

A Digitized Comparison using Cone Beam Computed Tomography and Intraoral Scanning , Yvette Carrillo

Theses/Dissertations from 2017 2017

Comparison of Antibacterial Activity of Ozonated Olive Oil and Chlorhexidine Gluconate , Changmin Lee

Accuracy of a Newly Developed Guided Dental Implant Delivery System , Fallon D. Livingston

Theses/Dissertations from 2016 2016

Accuracy of Implants Placed with Surgical Guides: Thermoplastic vs. 3-D Printed , Caitlyn K. Bell

Accuracy of Volumetric Analysis Software Packages in Assessment of Tooth Volume Using CBCT , Saylee Nimbalkar

Influence of Low Temperature Degradation on Microstructural Integrity of Zirconia Dental Implants , Mona Monzavi Rahimi

Theses/Dissertations from 2014 2014

Novel Approach to Assess Periodontal Disease Severity Using Volumetric Analysis , Meera George Maveli

Factors Affecting Gingival Recession in the Esthetic Zone: A Human Cadaver Study , Christen Sather

Theses/Dissertations from 2012 2012

Identification of the Mandibular Nerve with CBCT Using a Nerve Marking Tool or Not , Myung Soo Choi

Theses/Dissertations from 2009 2009

Factors Influencing Contrast Resolution of Cone Beam CT Using the CB MercuRay , Roger M. Anderson

Theses/Dissertations from 2007 2007

Reproducibility of Two Non-Consecutive Scans Using a NewTom 3G; in Vitro Model , Hyoung Jin Park

Theses/Dissertations from 2006 2006

Training Program to Improve Estimation of Patients' Periodontal Pain Experience , Yoon Jeong Kim

Influence of Keratinized Mucosa, Bone Dimensions on Mucosal Recession and Bone Loss , Jeanette Keng Ling Chua

Theses/Dissertations from 2005 2005

Comparison of Different Methods of Assessing Ridge Width prior to Implant Placement , Lung-Cheng Chen

Resonance Frequency Analysis as a Determinant of Implant Initial Stability , Negar Tabandeh

Theses/Dissertations from 2004 2004

Pain Experienced by Patients during Periodontal Examination , Mohammed A. Al-Ajmi

Pain Experienced by Patients Using Thinner vs. Thicker Probes During Probing , Mohamed A. Hassan

Effect of Anti-TGFß1 and Pycnogenol® on Scar Formation in Rats , Pilseong Kim

Theses/Dissertations from 2003 2003

Healing Following Placement of a Subperiosteal Orthodontic Anchoring Device , Oliver Hoffmann

Assessment of Alveolar Bone Density Using Implant Insertion Resistance Torque , Scott Sangmoo Lee

Theses/Dissertations from 2002 2002

IL-10 and Alveolar Bone Loss , Abdulaziz Saud Al-Rasheed

Assessment of Human Alveolar Bone Density by Using Volumetric CT Machine , Prasit Aranyarachkul

Pain Experienced by Patients during Periodontal Recall Treatment , Thu-Diem Chung

Theses/Dissertations from 2001 2001

Probing Bone Level Measurements for Determination of the Depths of Class II Furcation Defects , Youngil Suh

Theses/Dissertations from 1998 1998

Regeneration In Periodontal Defects with rhBMP-2 : A Dosage Study , Paola Guglielmoni

Theses/Dissertations from 1996 1996

Bone Morphogenetic Proteins and Periodontal Repair , Michael B. Lee

Periodontal Repair in Dogs : Effect of Recombinant Human Transforming Growth Factor Beta-1 on Guided Tissue Regeneration , Saghi Shayan Razi

Theses/Dissertations from 1995 1995

Periodontal Repair in Dogs : Evaluation of rhBMP-2 Carriers , Lauralee Nygaard

Alveolar Bone and Cementum Regeneration Following Periodontal Reconstructive Therapy : A Review of Histologic Observations In Man and Experimental Animals , Karen E. Rodden

Theses/Dissertations from 1994 1994

Healing Following Periodontal Reconstructive Surgery : Surgical Implantation of a Collagen Matrix or Demineralized Freeze-dried Bone Allograft , Seong Yong Choi

Periodontal Repair in Dogs : Part I : Evaluation of the Natural Disease Model ; Part II : ePTFE Barrier Membranes Support Wound Stabilization and Enhance Bone Regeneration , James Marc Haney

Theses/Dissertations from 1993 1993

Reproducibility of Periodontal Probing , Su-Fang Wang

Theses/Dissertations from 1992 1992

Transforming Growth Factor-Beta 1 Expression in Developing Ovine Teeth as Visualized by In Situ Hybridization , Søren Jepsen

The Periodontal Intraosseous Defect Following Root Conditioning with Citric Acid and Wound Closure Including a PTFE Membrane : An Experimental Study , Betty Glaser Kersten

Theses/Dissertations from 1989 1989

The Effect of an Anti-Osteoclastic Agent and a Collagen Sponge on Root Resorption Following Regenerative Periodontal Surgery in the Dog , Rudolf Hahn

Theses/Dissertations from 1988 1988

Treatment of Periodontal Furcation Defects , Michael Martin and Bernard Gantes

Theses/Dissertations from 1987 1987

Treatment of Periodontal Furcation Defects , Bernard Gantes

Effects of Oral Hygiene Measures on Clinical and Microbiological Parameters of Periodontal Disease , Bruno Loos

Theses/Dissertations from 1984 1984

Predictions of the Effects of Nonsurgical Periodontial Therapy : Prospective and Retrospective Identification of Deteriorating Sites , Rik Achille Vanooteghem

Theses/Dissertations from 1982 1982

Healing Following Two Different Surgical Approaches to Treating Deep Periodontal Intraosseous Defects , A. Durwin H. Chamberlain

Theses/Dissertations from 1981 1981

The Effect of Mechanical Plaque Control on the Clinical Parameters of Human Periodontal Disease , John F. Cercek Jr.

Histologic Probe Position in Treated and Untreated Human Periodontal Tissues , Clifford Fowler

Theses/Dissertations from 1980 1980

Changes of the Marginal Periodontium as a Result of Labial Tooth Movement in Monkeys , Gregory G. Steiner, J. K. Pearson, and J. Ainamo

Evaluation of New Attachment Following Full Thickness Flap Procedure in Humans , Shaunda S. Steiner

Theses/Dissertations from 1978 1978

New Attachment of Connective Tissues to Human Teeth Involved in Chronic Periodontal Disease : A Histologic Study , Rick Cole

Ultrastructural Study of Wound Healing on a Root Planed and Citric Acid Treated Root Surface , Craig Martin Ririe

Theses/Dissertations from 1977 1977

A Comparison of a Step-by-Step versus an All-in-one Approach in Teaching Plaque Control , Charles R. Woofter

Theses/Dissertations from 1976 1976

The Effects of Topically Applied Citric Acid on Periodontally Diseased Root Surfaces , John S. Garrett

Gingival Condition in Areas of Minimal and Appreciable Widths of Keratinized Gingiva , Myles C. Miyasato

Theses/Dissertations from 1975 1975

Developing a Periodontal Screening Examination , Jeffrey R. Morgulis

The Effect of Chlorhexidine or Oxytetracycline Irrigation on the Subgingival Microbiota , George M. Whitehead

Theses/Dissertations from 1973 1973

The Effect of Post-Operative Use of Chlorhexidine on Periodontal Regeneration in Monkeys with Chronic Bifurcation Defects , J. Pat Bishop

Effect of Tooth Cleaning Procedures on Gingival Sulcus , Klaus D. Wolfram

Theses/Dissertations from 1972 1972

The Effect of Oral Allografts of Cancellous Bone and Marrow in Mice , George E. Deeb

Microscopic Evaluation of Topically Applied Chlorhexidine Gluconate on Gingival Wound Healing in Dogs , Robert C. Hirst

Marrow Isografts in the Oral Cavity of Mice , Robert L. Merin

Theses/Dissertations from 1971 1971

Root Exposure and its Effect on the Fluid Movement within the Tooth , William J. Busch

The Response of Gingival Tissues to Alterations in pH , Robert C. Jann

A Clinical and Microscopic Evaluation of Plaque Removal and by the Hydrodent Brush , Soertini E. Lambri

The Effect of Elevated Glucose on Neutrophilic Phagocytosis in Genetically Diabetic Mice , Larry B. Thompson

Theses/Dissertations from 1970 1970

An In Vivo Perfusion Apparatus for Studies on Gingival Disease in the Albino Rat : Assessment by a Perfusion of the Enzymes Collagenase and Hyaluronidase , James A. Smith

Theses/Dissertations from 1969 1969

An In Vivo Perfusion Apparatus for Studies on Gingival Disease : Assessment by a Perfusion of Nonspecific Proteolytic Enzymes , Don Dornan

The Effect of a Patient-Counseling Film and Hygienist on the Oral Hygiene of Junior High School Students , Leonard L. Espinda

Theses/Dissertations from 1968 1968

A Study of Alveolar Bone Loss and Two-Hour Postprandial Blood Sugar Levels , R. Leslie Arnett

Theses/Dissertations from 1967 1967

The Effect of Glucose on Neutrophilic Phagocytosis , Donald F. Adams

Theses/Dissertations from 1962 1962

The Pathogenesis of Periodontal Disease and Treatment Implications , Richard C. Oliver

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Periodontics articles from across Nature Portfolio

Related subjects.

• Dental implants
• Gingival recession
• Gum disease
• Peri-implantitis
• Periodontitis

Latest Research and Reviews

Effect of photobiomodulation therapy with 660 and 980 nm diode lasers on differentiation of periodontal ligament mesenchymal stem cells

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The effectiveness of autologous platelet-rich concentrates as an adjunct during nonsurgical periodontal therapy: a systematic review and meta-analysis of randomized controlled trials

• Nazurah Nik Eezammuddeen
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Microsurgery in periodontics and oral implantology: a systematic review of current clinical applications and outcomes

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MicroRNA expression in JAG1/Notch-activated periodontal ligament stem cells

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Insights into the antioxidant, anti-inflammatory and anti-microbial potential of Nigella sativa essential oil against oral pathogens

• Shaeesta Khaleelahmed Bhavikatti
• Siti Lailatul Akmar Zainuddin
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The PocketPerio application significantly increases the accuracy of diagnosing periodontal conditions in didactic and chairside settings

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News and Comment

Slow drilling technique may enhance peri-operative patient-reported outcomes in dental implant surgery.

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Maintaining periodontally compromised teeth seems more cost-effective than replacing them with dental implants

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Does periodontitis have any association with mild cognitive impairment?

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Short-term data suggests cognitive benefits in the elderly with single-implant overdentures

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Is there a correlation between peri-implantitis and systemic inflammation?

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e-Publications@Marquette

Home > Dentistry > dissertations

School of Dentistry Dissertations and Theses

The School of Dentistry Dissertations and Theses Series is comprised of dissertations and theses authored by Marquette University's School of Dentistry doctoral and master's students.

Theses/Dissertations from 2024 2024

IN VITRO COMPARISON OF CELLULAR CYTOXICITY OF CONVENTIONAL VS. CAD/CAM DENTURE BASE MATERIALS , Zainab Hill Albasry

A COMPUTATIONAL FLUID DYNAMICS ANALYSIS COMPARING IRRIGATION WITHIN COMPLEX ROOT CANAL ANATOMY , Madeleinne Fern

Impact of Learning-Style-Based Education on Student Performance and Perception in Preclinical Endodontics: Part II , Rebecca Flaugher

PREEMPTIVE ANALGESIA AND PAIN AFTER PERIODONTAL AND IMPLANT- RELATED PROCEDURES: A SYSTEMATIC REVIEW AND META-ANALYSIS , Christos Gousias

Sleeveless guides are more accurate than sleeved guides: An in vitro study , Jenna Hang

RELIABILITY OF THE CVMS METHOD TO ASSESS THE CRANIOFACIAL GROWTH SPURT , Holly Ingersoll

Morphology of the Cranial Base of Untreated Class I and Class II Subjects , Ethan Just

Performance and Preference of Rotary Files by Pre-Doctoral Dental Students at Marquette School of Dentistry , Morgan Elizabeth McCall

Contribution of Dentoalveolar Heights on Facial Heights in Class I and Class II Untreated Subjects , Mira Bharat Suvagia

ORTHODONTIC LOAD QUANTIFICATION LEVELING A DEEP CURVE OF SPEE WITH DIFFERENT ARCHWIRE DESIGNS , Ahmed Youssef

Theses/Dissertations from 2023 2023

Effects of Thermocycling and Hydrolytic Aging on The Flexural Strength of Additively Manufactured Restorative Materials , Steven Mustafa Abu Al Tamn

LONG-TERM ASSESSMENT OF SKELETAL AND DENTAL ASYMMETRY AFTER CONVENTIONAL AND MINI-SCREW ASSISTED RAPID PALATAL EXPANSION , Brett Barton

Maxillary and Mandibular Incisor and Molar Dentoalveolar Heights in Untreated Subjects Presenting Class I and Class II Malocclusion , Samantha Zavada Cardinal

Factors Associated with Extraction Versus Non-Extraction Treatment Among Orthodontic Patients at Marquette University , Kelley Dentino

Short and Long-Term Effects of Conventional and Miniscrew-Assisted Rapid Palatal Expansion on Hard Tissues Using Voxel-Based Superimposition of Serial CBCTs , Isaac R. Empson

The Effect of Endodontic Access Cavity Designs on Crack Propagation of Mandibular Molars , Colin Kodama

Alveolar Bone Remodeling In Response to Orthodontic Tooth Movement , Matthew Raymond McGrady

A Digital Assessment of Centric Relation Precision , Christine Roenitz

The Influence of the Digitization Method on the Assessment of Accuracy and Reliability of Implant Placements , Ajitesh Singh

Immediate Postoperative Dimensional Changes Following Implant Placement , Juan Felipe Valencia Rincon

The Influence of Peri-Cervical Dentin Conservation on the Propagation of Cracks in Mandibular Molars , Hassanain Zaheer

Theses/Dissertations from 2022 2022

Edge-Chipping and Translucency Comparison Among Lithium Silicate-Based Ceramics , Essa Abdullah Alghamdi

Associations Between the Movement of Hard and Soft Tissues After Orthodontic Proclination of Incisors , Scott Beard

Evaluation of Damon PSL and Conventional MBT Brackets in Leveling and Alignment Efficiency , Jacob Beckstrand

Activated Charcoal Versus a Chemical Whitening Agent: Effect on Human Enamel , Hien Thai Doan

Color Characterization of Color Changing Orthodontic Adhesives , Megan Fried

Influence of Free-End Distal Extension on the Accuracy of Guided Implant Placement: An In Vitro Study , Geoffrey Ganzman

Influence of Multiple Root-End Surgery or Root Amputation on Root Surface Stress Distribution , John Curtis Jurkas

Autoignition and Sooting Characteristics of Iso-Octane and Ethanol in an Optical Rapid Compression Machine , Richard John Kempf

The Effect of Tray Design and Impression Material Consistencies on Accuracy of Complete Arch Implant Supported Fixed Dental Prostheses Master Casts , lujain Kurdi

Immediate Postoperative Dimensional Changes Following Guided Bone Regeneration , Morvarid Monfaredzadeh

The Accuracy and Sensitivity of ABO Electronic Cast Radiographic Program ORTHOSHARE 360 Compared to Manual Measurements , Lisa Nguyen

Identifying Optimal Composite Resin Depth to Maximize Fracture Resistance when Restoring Immature Endodontically Treated Teeth , David Poe

Mechanism of Mechanical Vibration in Enhancing Orthodontic Retention- Analysis of Global Gene Expression , Shuwei Wang

Theses/Dissertations from 2021 2021

In Vitro Study to Analyze Reverse Torque Values of Prosthetic Screws with Multiple Loosening/Tightening Preload Cycles , Amira Alhameed

Effects of Cleaning Agents on the Properties of Two Different Thermoplastic Retainer Materials , Jennifer Brehove

Correction of Excessive Gingival Display: Lip Repositioning with/without Myotomy , Austin Michael Dodge

The Influence of the Operator Experience on the Accuracy of Implant Placement: An In Vitro Study , Jeffrey Garcia

Root-End Surgery or Nonsurgical Retreatment: Are There Differences in Long Term Outcome? , Enida Haxhia

Mechanism of Mechanical Vibration in Enhancing Orthodontic Retention , Brent A. Ito

The Incidence of Root Canal Therapy or Extraction after Orthodontic Treatment: A Ten-Year Retrospective Study , Thomas Korte

Outcomes of Nonsurgical Root Canal Therapy Completed in Children Aged 6-13 Years , Lauren M. Loney

Comparing Orthodontic Debonding Aerosol Production with Various High-Volume Evacuation Systems , Eric Moe

Bending and Phase Transformation Properties of a Force Gradient Nickel-Titanium Orthodontic Wire , Brinda Shah

Effects of Fluoride on Corrosion Properties of Orthodontic Retention Wires , John J. Simindinger

Shear Bond Strength Characteristics on Surface Treatment Modalities of CAD-CAM Resin Based Core Materials , Nikita Sinha

Theses/Dissertations from 2020 2020

Oral Health and Quality of Life: A Clinic-Based Sample , Kinan M. Al-Bitar

Peri-Implantitis Risk Prediction Using a Computer Based Periodontal Risk Calculator Tool: A Retrospective Study , Walaa AL Zaibak

Assessment of 3D Facial Scan Integration in 3D Digital Workflow Using Radiographic Markers and Iterative Closest Point Algorithm , Mohamed Elshewy

Outcomes of Primary Endodontic Therapy in Medicaid Enrollees , Timothy Gainey

Corrosion Properties of Various Orthodontic Fixed Retention Wires , Tara Lynn Groen

Anatomical Considerations for Miniplate-Anchored Maxillary Protraction in Children with Unilateral Cleft Lip and Palate , Jared Holloway

Efficacy of Invisalign: A Retrospective Case Series of Intrusion, Extrusion, and Rotation with Trend Analysis , Kirsten Karkow

The Effect of Mechanical Vibration on Alveolar Bone Following Experimental Periodontitis: A Time Course Study , Joshua Murphy

Accuracy of Merging Scans of Definitive Fixed Prosthodontic Impressions to Obtain Single, Accurate Digitized Master Casts , Ossama Raffa

Tensile Strength of Elastomeric Ligature Ties Stretched Over Large and Small Orthodontic Brackets , Golden Shiloh

Influence of Progressive vs. Minimal Canal Preparations on the Fracture Resistance of Mandibular Molars: A Finite Element Analysis , Michael Smoljan

Impact of Delayed Completion of Previously Initiated Therapy and Provider Type on Outcomes of Root Canal Treatment , Igor Sulim

Theses/Dissertations from 2019 2019

The Cytotoxicity Effect of Silver Solder Materials on Human Periodontal Ligament Fibroblast Cells , Joseph Jeffrey Curry

An in Vitro Study of Surface Alterations to PEEK and Titanium and Its Effect Upon Human Gingival Fibroblasts , Maryam Gheisarifar

Effect of Heat-Treatment Time on Bending Properties of Cobolt-Chromium Orthodontic Wires , Melanie Hammerbeck

The Design and Physical Properties of An Optimized Chitosan Hydrogel for Potential Use in Endodontics , Hunter Housley

Comparison of Power Versus Manual Toothbrush in Reducing Gingivitis , Keerthi Kamreddy

Efficacy of Invisalign Attachments: A Retrospective Study , Theresa Karras

Evaluation of Corrosion Mechanisms in Stainless Steel Orthodontic Retainer Wires , Jamie Martin

Injectable Gels with Potential Use in Endodontics , Maksim Montatskiy

Effect of Different Implant Abutment Materials on Optical Properties of Translucent Monolithic Zirconia Crowns , Nisha Patel

Evaluation of Accuracy of Static Computer-Guided Implant Placement Compared with Partially-Guided or Free-Hand Placement , Laxmi Sukhtankar

The Effect of Mechanical Vibration on Alveolar Bone Following Experimental Periodontitis - A Micro-CT Study , Andrei Dan Taut

The Influence of Full Coverage Restorations On Pulp Vitality: A Ten-Year Retrospective Study , Abby Yavorek

Theses/Dissertations from 2018 2018

Effect of Different Finish Line Designs on the Marginal and Internal Fit of Metal Copings Made by Selective Laser Melting Technology , Adel Al Maaz

Effect of Emergence Profile of a Single Implant Restoration on the Health of Peri-Implant Soft Tissue , Waleed Nasir Asiri

Application of Mechanical Vibration to Enhance the Stability After Orthodontic Treatment - A Micro - CT Study , Nicolas Branshaw

A Retrospective Analysis of Patient Medical and Dental Treatment Histories, and MRONJ-Related Events , Jon Irelan

Orthodontic Bond Strength Comparison Between Two Filled Resin Sealants , James Kolstad

Comparison of Immediate vs. Delayed Recall of Orthodontic Information Following an Electronic Reminder , Michael Lenz

Orthodontic Open-Coil Spring Deactivation Forces Differ with Varying Activation Levels , Ryan Lubinsky

Factors Effecting Survival of Teeth with Nonsurgical Root Canal Therapy Including a Multi-State Outcome Analysis , Alex Moore

Orthodontic Treatment Planning Using Direct Visual Approximation of Arch Length Discrepancy and Cephalometric Analyses , Kathleen Rouse Vaught

Comparison of Different Temperatures on Bending Properties of Six Niti Endodontic File Systems , Sukbum Yoo

Theses/Dissertations from 2017 2017

QMIX 2in1 and NaOCI Precipitate: Documentation, Identification, and Exothermic Reaction , Gordon L. Barkley III

Viability of Human Periodontal Ligament Fibroblasts After Time in Tooth Storage Media , Scott MacDonald

Effects of Palatal Expansion on Speech Production , Jason Milton Meinhardt

Reliability of Digital Dental Cast Measures as Compared to Cone-Beam Computed Tomography for Analyzing the Transverse Dimension , Brian Michel

Analysis of Flexural Strength and Monotonic Load to Failure Following Simulated Chairside Adjustments and Repair in a Lithium Disilicate Glass-Ceramic , Ali Ramadhan

The Effect of Heat Treatment on the Bending Properties of a Cobalt-Chromium Orthodontic Wire , Alex Schwab

Comparison of Anterior Denture Teeth Arrangements Made with the Tooth Mold Template and Definitive Computer-Aided Design & Computer-Aided Manufacturing Complete Removable Dental Prostheses , Jose Antonio Sierra

Thermal Properties of Commonly Used Clear Aligner Systems As-Received and After Clinical Use , Louis Wenger

Direct Visual Approximation of Arch Length Discrepancy and Cephalometric Measurements , Bradley J. Wurm

Survival Rates of Primary Endodontic Therapy Following Core/Post and Crown Placement , Kandace Yee

Theses/Dissertations from 2016 2016

Evaluation of Die Trim Morphology Made by CAD/CAM Technology , Pratiksha Agrawal

Outcomes of Primary Endodontic Therapy Provided by Endodontic Specialists Compared to Other Providers , Jacob Burry

The Effect of Mechanical Vibration on Human PDL Cell Differentiation and Response to Inflammation , Megan DesRoches

Color Change of Commercial Resin Composited with Different Photoinitiators , Feng Gao

The Effects of Mechanical Vibration on Human Chondrocytes In Vitro , Bradley J. Gauthier

Thermal Properties of Copper Nickel-Titanium Orthodontic Archwires , Joshua Gilbert

Torsion and Bending Properties of EdgeEndo Files , Chad Hansen

Mitigating Distortion of Light-Polymerized Composite Trial Bases , Jon Patrick Irelan

Viability of Human Periodontal Ligament Fibroblasts After Storage in Save-A-Tooth, EMT Toothsaver and Hank's Balanced Salt Solution , Wonhee Lee

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Full text for dissertations and theses included in this collection dates back to 2011. For older dissertations, check the library’s catalog CatalogUSMAI or Dissertations and Theses database .

Recent Submissions

Enhancing Cervical Composite Restorations Management

Comparison of Virtual Treatment Setup among Clear Aligner Companies

Comparing Accuracy of Commonly used Final Impression Techniques in Recording Excessively Movable Tissues in Completely Edentulous Patients.

Assessing language use patterns for terminology to describe bimaxillary protrusive phenotypes.

Saliva Levels of IL-18 in Healthy and Peri-implantitis Patients

Extra! Extra! Read All About It: A National Dental Survey of the Emergency Room Physician

Impact of Clear Aligners on the Risk of Biofilm-Induced Oral Diseases

Comparison of Feldspathic Veneer Surface Treatments on Color Stability after Debonding of Orthodontic Brackets: An In Vitro Study

Post-traumatic Hyperalgesia and Degeneration of Temporomandibular joints in mice: the role of nociceptive afferents

Novel Bioactive Low-Shrinkage-Stress Composite with Antibacterial and Remineralization Properties

The quality of information on oral hygiene instructions for orthodontic patients in TikTok videos

Perception of lip attractiveness: a survey of orthodontists, general dentists, and laypersons

Three-Dimensional Assessment of Virtual Clear Aligner Attachment Removal: A Prospective Clinical Study

Effect of Polydopamine-RGD Peptide Coating on the Adhesion of Cultured Fibroblasts on Polymethylmethacrylate Provisional Custom Abutment Materials

The Etiology of Peri-implantitis: Microbiological Profile Within and Around Dental Implants and the Associated Human Immune Response

Effect of Contact Type on Caries Experience in Primary Dentition

Comparison of Shear-bond Strength of Orthodontic Brackets on Enamel with use of Pro Seal with Assure Plus

Novel Bioactive Low-shrinkage-stress Nanocomposite with Antibacterial and Remineralization Properties and Thermal-cycling and Aging Resistance.

Soluble Immune Biomarkers as a Diagnostic Tool of Head and Neck Squamous Cell Carcinoma Histological Inflammatory Subtypes

The Trueness of additive and Subtractive Zirconia Crowns

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The Future of Periodontology

Even with the exciting advances seen in today’s periodontal treatment, more promising therapies loom on the horizon.

Over the decades, oral health care has seen many advances that have significantly impacted the practice of periodontics. One of periodontology’s greatest strengths is that it is not a static field; rather, it continues to evolve and readjust its focus on the basis of contemporary research spanning a vast array of scientific endeavor. A tantalizing list of topics that are currently under investigation is shown in Table 1 (page 18). Due to space limitations, this review will discuss some, but not all, of the developments that are expected to help reshape periodontal therapy over the next 10 years.

Accurate assessment of individual risk is considered one of the most important aspects of periodontal examination, diagnosis, prognosis and treatment planning. To date, this has been elusive, but, nonetheless, it will remain an important aspect of periodontal research and practice in the years to come. Recognition that periodontitis is a multifactorial disease involving a complex interplay between host, environment and microbes is central to current scientific understanding.1

While it is well accepted that development of periodontitis is intimately associated with the bacteria residing in the subgingival biofilm, it is also evident there are some patients who, despite the presence of considerable plaque deposits, do not develop periodontitis. Conversely there are individuals who develop advanced and destructive forms of periodontitis, yet appear to have minimal deposits of plaque. It seems that although plaque is necessary for periodontitis to develop, it alone is insufficient for the development of periodontal disease. 2,3

Indeed, it is now evident that in addition to plaque, other risk factors — such as opportunistic pathogens, environmental influences, genetics, host responses, connective tissue metabolism and bone metabolism — are critical to the clinical manifestation of periodontitis (Figure 1).

Understanding this multifactorial nature has led to the development of a more informed management process. Such processes dictate that, in addition to recognizing the fundamental role of oral hygiene, other risk factors that contribute to periodontitis must be controlled in order for treatment to be successful. 4,5 For example, plaque (and its constitutive elements) appears to account for only 20% of the risk for developing periodontitis. 6 Therefore, there must be another 80% of risk elements (i.e., modifying and predisposing factors) that must be taken into account when assessing a patient’s periodontal condition. This can be thought of as the personalized medicine/personalized dentistry approach to diagnosing and treating periodontal disease. 7

In the future, identifying individual risk factors within the paradigm of personalized medicine/personalized dentistry will become central to periodontal practice. In this context, the emerging field of genomics 8,9 will play an increasingly important role. Furthermore, completion of the human genome project now allows the utilization of sophisticated approaches — such as genome-wide screening of populations — to determine the genetic contributions to periodontitis in its various forms. 10 That noted, it is recognized that genetics alone cannot fully account for the etiology and progression of the disease process. 11

Epigenetics is the study of cellular and physiological phenotypic trait variations caused by external or environmental factors that switch genes on and off. 12 Clearly, this has great potential to impact scientific understanding of periodontitis and how environment and genes interact in the clinical manifestation of disease. 13,14 However, while it seems entirely probable this extra genetic material may have a great deal of interplay with disease, at present, its role is poorly understood.

Together, these new technologies are sure to represent essential components of future periodontal diagnosis and risk assessment.

HOST-PATHOGEN RELATIONSHIPS

Understanding the central role of the host response in the development of periodontitis also opens new avenues for patient management. These will not replace current treatment approaches of mechanical subgingival debridement, but will serve as adjuncts to traditional approaches to improve and hasten treatment outcomes. It is expected that such adjunct therapies aimed at controlling the host inflammatory response will also result in modification of the subgingival environment and, thus, significantly influence the microbial ecology.

The proposal of the “ecological plaque hypothesis” in 2003 was a significant development in the conceptual understanding of the subgingival environment and how the local environment can influence bacterial composition. 15,16 However, this hypothesis was poorly embraced because it was considered discordant with conventional periodontal microbiology concepts at the time that dictated specific bacteria were solely responsible for periodontitis. 17 Nonetheless, the concept that host modification of the periodontal pocket whereby inflammatory conditions select for so-called pathogenic species through a process known as “reciprocal interaction” was eventually embraced. 18 The process, by which the host can modify the subgingival bacterial environment, has significant ramifications for future host modulation based on controlling the inflammation, rather than focussing solely on elimination of infection. 2,19–21

Despite the defining role of the host response, the subgingival microbiota cannot be completely overlooked. Through the unravelling of the human microbiome, current understanding of how microbial communities interact — both with themselves, as well as the host — allows scientists and clinicians to view the periodontal microbiota and its role in the development and progression of periodontitis in a new light. 22 Recently, oral microbiologists have proposed the concept of bacterial dysbiosis as playing a key role in the pathogenesis of periodontitis. 23,24 In this model, changes within the subgingival milieu cause microbial shifts and imbalances, resulting in the overgrowth of pathogenic microbes. 25 This concept of polymicrobial synergy and microbial dysbiosis is well aligned with the role of host modulation of microbial periodontal infection described above, and supports the value of considering host modulation therapy as a viable adjunct to conventional treatment.

PERIODONTAL REGENERATION

Regeneration of tissues damaged by periodontitis has long been considered a key goal of periodontal treatment. Numerous techniques and products have been investigated to achieve periodontal regeneration, and these have generally involved root surface conditioning or implantation of bone substitutes into periodontal defects. Yet, despite efforts to improve periodontal regeneration, each of these procedures remains technique sensitive and clinically unpredictable. This is due, in part, to a lack of understanding of the requirements for periodontal regeneration — namely, the encouragement the regrowth of new cementum, bone and periodontal ligament. Nonetheless, the profession has become obsessed with filling holes in bone rather than studying the natural healing processes required to regenerate the periodontal attachment apparatus. 26 A lack of clarity regarding the contribution of the various tissue components in periodontal wound healing explains the widespread misuse of bone transplantation in the treatment of intrabony pockets that pervades some areas of periodontology. 27

It is now clear that periodontal regeneration must be founded on sound biologic principles, taking into account each functional stage of reconstruction. 28 By applying biologically sound principles to the problem of periodontal regeneration, the clinical procedure of guided tissue regeneration (GTR) was developed in the 1980s. 29 At the time, this was a significant advance. However, it soon became apparent that although periodontal regeneration was possible, it was difficult to achieve reliably due to a vast range of patient and operator variables. 30 More recently, the application of biological agents onto root surfaces has been shown to induce significant regeneration of damaged periodontal tissues. 31 Compared to GTR, an advantage is that biological agents are simpler to use and provide comparable — and sometimes superior — results. 32 Like GTR clinical outcomes, the regenerative capacity of biologic agents depends on many variables.

In recent years, implantation of mesenchymal stem cells into periodontal defects has been investigated as a means of inducing periodontal regeneration. 33 The first report about the isolation and characterization of periodontal ligament stem cells was published in 2004, and since then the field of dental stem cells has advanced quickly, particularly with regard to its potential use for periodontal regeneration. 34–37

Another recent development is the utilization of gene therapy for periodontal regeneration. However, this technology requires extremely sophisticated technical manipulation of cells and also results in considerable caries morbidity issues. 38,39

In order for these cell-based regenerative therapies to be successful, suitable delivery devices will need to be developed so the cells can be successfully delivered to the sites of interest. The development of biocompatible scaffolds will be crucial in the next phases of this technology. 40 Indeed, this is an active area of research involving the development of biodegradable materials, smart materials and three-dimensional bioprinting. 41–45

While the field of cell-based tissue engineering for periodontal regeneration is exciting and the future looks promising, considerable work must be done before such modalities can become a reliable and predictable approach to treatment. This will involve large-scale collaborative efforts between bioengineers, nanotechnologists, cell biologists and molecular biologists. As the field advances, other significant issues will include biosafety and sound manufacturing principles, as well controlling the cost of such technologies.

PERIODONTAL MEDICINE

The term “periodontal medicine” was coined in 1996. 46 In the ensuing years, the field has developed rapidly and generally encompasses the interactions between periodontal health and disease, and systemic health and disease. The defining concept is that periodontal inflammation and the periodontal microbiome interact, resulting in a significant increase in the overall level of systemic inflammation. In turn, this influences the incidence, severity and progression of other chronic inflammatory conditions. Furthermore, it has been proposed there may be a bidirectional relationship between periodontitis and some systemic conditions, in which periodontitis can affect systemic health — and the opposite may also occur.

Another issue that must be considered is causality versus association. While associations can be made easily, causality is a far more complex problem. Hill’s 47 criteria was developed to help determine causality (Table 2). If one considers these criteria, it would appear unlikely that periodontitis will be determined to be causal of other conditions. However, disease associations may be just as important to understand because they allow researchers to identify conditions and individuals who are likley to agreggate with common conditions and underlying pathologic processes. A disease association checklist has been proposed to help determine how a condition may be related to periodontitis. 48 By answering four questions (Table 3, page 22), it should be possible to determine the significance of an association, and whether it is likely to be real or spurious.

The emergence of periodontal medicine as a subdiscipline of periodontology has resulted in a new direction in the understanding of periodontal disease. Classical periodontal therapy has been focused only within the oral environment to preserve or restore the structure, function and esthetics of the dentition. However, science’s current understanding that periodontal inflammation and infection may be intricately associated with other chronic systemic conditions has led to a new focus directed to whole body health, and managing the negative effects of periodontitis on systemic health.

Periodontal medicine opens new vistas in periodontology, especially in the fields of using a medical approach to diagnosis and treatment. It also promotes closer interactions with medical colleagues, as well as educational opportunities to alert both the profession and community to the most significant interrelationships, and how these may impact general health and well being.

CONCLUDING COMMENTS

While there are many important topics that could be addressed, the topics that were selected for this review illustrate both the challenges facing periodontology, and the robust nature of this specialty. All of the topics and areas chosen for discussion have the potential to significantly impact prevention, diagnosis and management of one of the most common chronic inflammatory conditions afflicting humans. As periodontology and dentistry continue to evolve, one thing is abundantly clear: The future is exciting.

KEY TAKEAWAYS

• Accurate assessment of individual risk is considered one of the most important aspects of periodontal examination, diagnosis, prognosis and treatment planning.
• It is now evident that in addition to plaque, other risk factors — such as opportunistic pathogens, environmental influence, genetic factors, host responses, connective tissue metabolism and bone metabolism — are critical to the clinical manifestation of periodontitis.
• In the future, identifying individual risk factors within the paradigm of personalized medicine/personalized dentistry will become central to periodontal practice.
• In this context, the emerging field of genomics 8,9 will play an increasingly important role Epigenetics has great potential to impact scientific understanding of periodontitis and how environment and genes interact in the clinical manifestation of disease. 13,14  At present, however, its role is poorly understood.
• While the future looks promising for cell-based tissue engineering for periodontal regeneration, considerable work must be done before such modalities can become a reliable and predictable approach to treatment.
• Genco RJ, Borgnakke WS. Risk factors for periodontal disease. Periodontol 2000 . 2013;62:59–94.
• Bartold PM, Van Dyke TE. Periodontitis: a host-mediated disruption of microbial homeostasis. Unlearning learned concepts. Periodontol 2000 . 2013;62:203–217.
• Clarke NG, Hirsch RS. Personal risk factors for generalized periodontitis. J Clin Periodontol . 1995;22:136–145.
• Braun TM, Doucette-Stamm L, Duff GW, Kornman KS, Giannobile WV. Counterpoint: risk factors, including genetic information, add value in stratifying patients for optimal preventive dental care. J Am Dent Assoc . 2015;146:174–178.
• Lang NP, Suvan JE, Tonetti MS. Risk factor assessment tools for the prevention of periodontitis progression a systematic review. J Clin Periodontol . 2015;42(Suppl 16):S59–S70.
• Grossi SG, Zambon JJ, Ho AW, et al. Assessment of risk for periodontal disease. I. Risk indicators for attachment loss. J Periodontol . 1994;65:260–267.
• Kornman KS, Duff GW. Personalized medicine: will dentistry ride the wave or watch from the beach? J Dent Res . 2012;91(Suppl 7):8S–11S.
• Grant MM. What do ‘omic technologies have to offer periodontal clinical practice in the future? J Periodontal Res . 2012;47:2–14.
• Trindade F, Oppenheim FG, Helmerhorst EJ, Amado F, Gomes PS, Vitorino R. Uncovering the molecular networks in periodontitis. Proteomics Clin Appl . 2014;8:748–761.
• Vaithilingam RD, Safii SH, Baharuddin NA, et al Moving into a new era of periodontal genetic studies: relevance of large case-control samples using severe phenotypes for genome-wide association studies. J Periodontal Res. 2014;49:683–695.
• American Dental Association Council on Scientific Affairs. Genetics and oral health. Available at: ada.org/en/member-center/oral-health-topics/genetics-and-oral-health. Accessed October 3, 2017.
• Barros SP, Offenbacher S. Epigenetics: connecting environment and genotype to phenotype and disease. J Dent Res . 2009;88:400–408.
• Barros SP, Offenbacher S. Modifiable risk factors in periodontal disease: epigenetic regulation of gene expression in the inflammatory response. Periodontol 2000 . 2014;64:95–110.
• Larsson L, Castilho RM, Giannobile WV. Epigenetics and its role in periodontal diseases: a state-of-the-art review. J Periodontol . 2015;86:556–568.
• Marsh PD, Head DA, Devine DA. Ecological approaches to oral biofilms: control without killing. Caries Res . 2015;49(Suppl 1):46–54.
• Marsh PD. Dental diseases-are these examples of ecological catastrophes? Int J Dent Hyg . 2006;4(Suppl 1):3–10.
• Feres M, Cortelli SC, Figueiredo LC, Haffajee AD, Socransky SS. Microbiological basis for periodontal therapy. J Appl Oral Sci . 2004;12:256–266.
• Socransky SS, Haffajee AD. Periodontal microbial ecology. Periodontol 2000 . 2005;38:135–187.
• Gokhale SR, Padhye AM. Future prospects of systemic host modulatory agents in periodontal therapy. Br Dent J . 2013;214:467–471.
• Elavarasu S, Sekar S, Murugan T. Host modulation by therapeutic agents. J Pharm Bioallied Sci . 2012;4(Suppl 2):S256–S259.
• Hasturk H, Kantarci A, Van Dyke TE. Paradigm shift in the pharmacological management of periodontal diseases. Front Oral Biol . 2012;15:160–176.
• Darveau RP. Periodontitis: a polymicrobial disruption of host homeostasis. Nat Rev Microbiol . 2010;8:481–490.
• Hajishengallis G. Periodontitis: from microbial immune subversion to systemic inflammation. Nat Rev Immunol . 2015;15:30–44.
• Pérez-Chaparro PJ, Gonçalves C, Figueiredo LC, et al. Newly identified pathogens associated with periodontitis: a systematic review. J Dent Res . 2014;93:846–858.
• Darveau RP, Hajishengallis G, Curtis MA. Porphyromonas gingivalis as a potential community activist for disease. J Dent Res . 2012;91:816–820.
• Becker W, Becker BE. Periodontal regeneration: a contemporary reevaluation. Periodontol 2000 . 1999;19:104–114.
• Karring T, Nyman S, Lindhe J, Sirirat M. Potentials for root resorption during periodontal wound healing. J Clin Periodontol . 1984;11:41–52.
• Bartold PM, McCulloch CA, Narayanan AS, Pitaru S. Tissue engineering: a new paradigm for periodontal regeneration based on molecular and cell biology. Periodontol 2000 . 2000;24:253–269.
• Karring T, Nyman S, Gottlow J, Laurell L. Development of the biological concept of guided tissue regeneration — animal and human studies. Periodontol 2000. 1993;1:26–35.
• Reynolds MA, Kao RT, Camargo PM, et al. Periodontal regeneration — intrabony defects: a consensus report from the AAP Regeneration Workshop. J Periodontol. 2015;86(Suppl 2):S105–S107.
• Stavropoulos A, Wikesjö UM. Growth and differentiation factors for periodontal regeneration: a review on factors with clinical testing. J Periodontal Res . 2012;47:545–553.
• Koop R, Merheb J, Quirynen M. Periodontal regeneration with enamel matrix derivative in reconstructive periodontal therapy: a systematic review. J Periodontol. 2012;83:707–720.
• Bassir SH, Wisitrasameewong W, Raanan J, et al. Potential for stem cell-based periodontal therapy. J Cell Physiol . 2016;231:50–61.
• Seo BM, Miura M, Gronthos S, et al. Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet . 2004;364:149–155.
• Bartold PM, Gronthos S. Standardization of criteria defining periodontal ligament stem cells. J Dent Res . 2017;96:487–490.
• Zhu W, Liang M. Periodontal ligament stem cells: current status, concerns, and future prospects. Stem Cells Int . 2015;2015:972313.
• Hynes K, Menicanin D, Gronthos S, Bartold PM. Clinical utility of stem cells for periodontal regeneration. Periodontol 2000 . 2012;59:203–227.
• Rios HF, Lin Z, Oh B, Park CH, Giannobile WV. Cell- and gene-based therapeutic strategies for periodontal regenerative medicine. J Periodontol . 2011;82:1223–1237.
• Su F, Liu SS, Ma JL, Wang DS, E LL, Liu HC. Enhancement of periodontal tissue regeneration by transplantation of osteoprotegerin-engineered periodontal ligament stem cells. Stem Cell Res Ther . 2015;6:22.
• Bartold PM, Xiao Y, Lyngstaadas SP, Paine ML, Snead ML. Principles and applications of cell delivery systems for periodontal regeneration. Periodontol 2000 . 2006;41:123–135.
• Rasperini G, Pilipchuk SP, Flanagan CL, et al. 3D-printed bioresorbable scaffold for periodontal repair. J Dent Res . 2015;94(Suppl 9):153S–157S.
• Bartold PM, Gronthos S, Ivanovski S, Fisher A, Hutmacher DW. Tissue engineered periodontal products. J Periodont Res . 2016;51:1–15.
• Obregon F, Vaquette C, Ivanovski S, Hutmacher DW, Bertassoni LE. Three-dimensional bioprinting for regenerative dentistry and craniofacial tissue engineering. J Dent Res . 2015;94(Suppl 9):143S–152S.
• Ivanovski S, Vaquette C, Gronthos S, Hutmacher DW, Bartold PM. Multiphasic scaffolds for periodontal tissue engineering. J Dent Res . 2014;93:1212–1221.
• Park CH, Kim KH, Rios HF, Lee YM, Giannobile WV, Seol YJ. Spatiotemporally controlled microchannels of periodontal mimic scaffolds. J Dent Res . 2014;93:1304–1312.
• Offenbacher S. Periodontal diseases: pathogenesis. Ann Periodontol . 1996;1:821–878.
• Hill AB. The environment and disease: association or causation? Proc R Soc Med . 1965;58:295–300.
• Bartold PM, Mariotti A. The future of periodontal-systemic associations: raising the standards. Curr Oral Health Rep. 2017;4:258–262.
• Linden GJ, Lyons A, Scannapieco FA. Periodontal systemic associations: review of the evidence. Jointly published in: J Clin Periodontol . 2013;40(Suppl 14):S8–S19. J Periodontol . 2013;84(Suppl 4):S8–S19

The author has no commercial conflicts of interest to disclose.

FEATURED IMAGE: BRIANAJACKSON/ISTOCK/GETTY IMAGES PLUS

From Decisions in Dentistry . January 2018;4(1):8-10,12.

P. Mark Bartold, DDSc, PhD, is a professor emeritus at the University of Adelaide and formerly a professor of periodontics and director of the Colgate Australian Clinical Dental Research Centre at the University of Adelaide in Australia. He is a fellow of the Royal Australasian College of Dental Surgeons in the Special Stream of Periodontics, and also a fellow of the Academy of Dentistry International, International College of Dentists and the Pierre Fauchard Academy. Bartold serves on Decisions in Dentistry’s Editorial Advisory Board, and is editor of the Australian Dental Journal and Journal of the International Academy of Periodontology. An author of more than 285 scientific articles, he can be reached at [email protected].

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The 300 most cited articles published in periodontology

Affiliations.

• 1 Department of Periodontology and Operative Dentistry, Faculty of Dentistry, University of Münster, Münster, Waldeyerstraße 30, 48149, Münster, Germany. [email protected].
• 2 Department of Clinical Stomatology, Section of Periodontology and Implants, Cayetano Heredia Peruvian University, Lima, Peru.
• 3 Department of Periodontics and Oral Medicine, University of Michigan, Ann Arbor, USA.
• 4 Department of Conservative Dentistry, Heidelberg University, Heidelberg, Germany.
• 5 Department of Quality and Safety of Oral Health Care, Radboud University, Radboud UMC, Nijmegen, The Netherlands.
• PMID: 27844151
• DOI: 10.1007/s00784-016-1990-1

Objectives: It is important to evaluate the characteristics of the most cited articles in any specialty. The number of citations may be a proxy for clinical and research activity. The objectives of the present methodological study were (1) to report the characteristics of the 300 most cited articles in periodontology and (2) to explore the association of these characteristics with the number of citations.

Methods: We searched in the Web of Science database for the 300 most cited articles published in periodontology on June 15, 2015. We described characteristics of the articles such as type of study, type of scientific journal, topic reported, year of publication, affiliation of the first author of the article, and impact factor. Linear regression analysis was used to investigate associations of these variables with the number of citations.

Results: The search retrieved approximately 155,356 publications; out of the studies that met the eligibility criteria, the 300 most cited were included for analysis. Comprising more than 50 % of the included articles, basic biology and the detection of bacteria were the most prevalent topics. Narrative reviews were the most frequent type of article (27 % of the sample). Regression analysis demonstrated that some characteristics, for example "narrative reviews," are more prone to be cited than others.

Conclusion: We conclude that scientific evolution in periodontology has been based more on narrative reviews than on reproducible systematic reviews.

Clinical relevance: Future research is encouraged to elucidate the extent to which scientific progress is improved through systematic compared with narrative reviews.

Keywords: Journal impact factor; Methodological study; Periodontics; Study characteristics.

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Upcoming xvi th national pg convention of indian academy of oral pathologists in subharti dental college, 24-25th june 2017, latest news @ sdc, oral hygiene day celebrated, cde on integrating periodontics for accelerated orthodontics, world health day was celebrated in subharti dental college & hospital, subharti dental college celebrated annual cultural and sports week – impulse 2016 ., bls course organized for students and faculty, orientation programme for the new batch of bds 2015 was held on 1st of september 2015., teacher’s day celebrated in subharti dental college, dentist day, continuing dental education programme, bds students and interns won 8 gold medals, celebrated annual cultural and sports week, dr. nikhil srivastava elected as executive committee member, dr. nikhil srivastava awarded with the prestigious star pedodontist award, fresher's day, subharti students win medals.