Advances in the science and treatment of alcohol use disorder
The alcohol and addiction research domain criteria (AARDoC) , which have been operationalized in the addictions neuroclinical assessment , focus on the following three domains that correspond to particular phases in the addiction cycle: incentive salience in the binge/intoxication phase, negative emotionality in the withdrawal/negative affect ...
Evidence-Based Pharmacotherapies for Alcohol Use Disorder
Pathologic alcohol use affects more than 2 billion people and accounts for nearly 6% of all deaths worldwide. There are three medications approved for the treatment of alcohol use disorder by the US Food and Drug Administration (FDA): disulfiram, naltrexone (oral and long-acting injectable), and acamprosate. Of growing interest is the use of anticonvulsants for the treatment of alcohol use ...
Advances in the science and treatment of alcohol use disorder
Only a small percent of individuals with alcohol use disorder contribute to the greatest societal and economic costs ().For example, in the 2015 National Survey on Drug Use and Health survey (total n = 43,561), a household survey conducted across the United States, 11.8% met criteria for an alcohol use disorder (n = 5124) ().Of these 5124 individuals, 67.4% (n = 3455) met criteria for a mild ...
Evidence-based models of care for the treatment of alcohol use disorder
It is well recognized that alcohol use disorders (AUD) have a damaging impact on the health of the population. According to the World Health Organization (WHO), 5.3% of all global deaths were attributable to alcohol consumption in 2016 [].The 2016 Global Burden of Disease Study reported that alcohol use led to 1.6% (95% uncertainty interval [UI] 1.4-2.0) of total DALYs globally among females ...
Addiction as a brain disease revised: why it still matters, and the
For alcohol addiction, meta-analysis of twin and adoption studies has estimated heritability at ~50%, while estimates for opioid addiction are even higher [44, 45]. Genetic risk factors are to a ...
Developing neuroscience-based treatments for alcohol addiction: A
Excessive alcohol use is the cause of an ongoing public health crisis, and accounts for ~5% of global disease burden. A minority of people with recreational alcohol use develop alcohol addiction ...
Genome-wide association study of alcohol consumption and use ...
Gelernter, J. et al. Genomewide association study of alcohol dependence and related traits in a Thai population. ... This research is based on data from the Million Veteran Program (MVP), Office ...
Alcohol, Clinical and Experimental Research
Alcohol, Clinical and Experimental Research provides direct access to the most significant and current research findings on the nature and management of alcoholism and alcohol-related disorders. Read Virtual Issues on key topics in the field of Addiction ... This study reveals that escalating drinking in certain U.S. adult subpopulations is a ...
Substance Use Disorders and Addiction: Mechanisms, Trends, and
The numbers for substance use disorders are large, and we need to pay attention to them. Data from the 2018 National Survey on Drug Use and Health suggest that, over the preceding year, 20.3 million people age 12 or older had substance use disorders, and 14.8 million of these cases were attributed to alcohol.When considering other substances, the report estimated that 4.4 million individuals ...
Alcohol: Clinical and Experimental Research
This study examined associations between alcohol outcomes (e.g., alcohol dependence, alcohol-related problem consequences), help-seeking, and treatment satisfaction among a community sample of 722 sexual minority women (SMW) by age, sexual identity, race/ethnicity, and income.
The association of alcohol dependence and consumption during
Among adolescents, studies of whether alcohol dependence increases risk of subsequent depression have several limitations, and evidence on frequency and quantity of consumption is inconsistent. ... Another limitation of research on alcohol use and depression among adolescents is that most participants were born during the 1970s or early 1980s ...
DAD
About the journal. Drug and Alcohol Dependence is an international journal devoted to publishing original research, scholarly reviews, commentaries, and policy analyses in the area of drug, alcohol and tobacco use and dependence. Articles range from studies of the chemistry of substances of abuse, their actions at molecular and cellular sites ...
Alcohol Use Disorder Clinical Trials
The purpose of this study is to evaluate the safety, tolerability and effectiveness of V117957, compared to placebo, in subjects with alcohol use disorder (AUD) who experience insomnia associated with alcohol cessation. Alcohol abuse and dependence remain highly prevalent and disabling. Persistent low treatment rates and high relapse rates ...
Alcohol and the Etiology of Depression
Cessation of alcohol use is associated with substantial reductions in depressive symptoms, as demonstrated, for example, in the classic studies of Brown, Schuckit, and colleagues among veterans hospitalized with alcohol use disorder ( 2, 3 ). This suggests a toxic effect of alcohol on depression. DSM-IV and DSM-5 ( 4, 5) introduced the ...
Brain Matters: OSU-CHS researchers studying semaglutide for possible
Dr. W. Kyle Simmons — Oklahoma State University Center for Health Sciences professor of pharmacology and physiology — is leading the Semaglutide Therapy for Alcohol Reduction study at OSU's Hardesty Center for Clinical Research and Neuroscience to determine whether semaglutide can be used to treat alcohol use disorder.
Age-related differences in the effect of chronic alcohol on cognition
While most of our knowledge on the effects of alcohol on the brain and cognitive outcomes is based on research in adults, several recent reviews have examined the effects of alcohol on the brain ...
VCAR Science Day brings leading addiction researchers together
The Vanderbilt Center for Addiction Research hosted Science Day on April 18. The annual event, which started in 2017, featured the latest research in addiction, including investigations into alcohol, opioids, and stimulants. ... where he studies the neural mechanisms underlying habit formation, ...
Insomnia medication shows promise in treatment for alcohol use disorder
Researchers are recommending full-scale human trials after an insomnia drug helped a man withdraw from his 16 drinks-a-day addiction. Minister for Education and Medical Research Hon Ben Carroll ...
Alcohol-Related Deaths of US Health Care Workers
Despite an increase in alcohol-related deaths in the US over the last 2 decades, 1,2 little is known about alcohol-related mortality risks among physicians 3 and other health care workers. Compared with non-health care workers, health care workers have increased drug overdose death risks. 4 An occupational liability to substance use or to risks of painful injuries and access to controlled ...
Scientists identify potential neural pathway to treat alcohol ...
The new study aimed to investigate whether inhibiting CRF-expressing neurons in this region could reduce alcohol consumption in a rat model of comorbid PTSD and AUD, thereby identifying a ...
Episode 22: Donita Robinson, PhD, UNC Department of Psychiatry & Bowles
Episode 22: Donita Robinson, PhD, UNC Department of Psychiatry & Bowles Center for Alcohol Studies May 8, 2024 January & February 2024 Newsletter March 18, 2024 November ... Center for Addiction Research & Education University of Florida Physical Address 1395 Center Dr, Suite D2-013 Gainesville, FL 32610 ...
The Alcohol Research Lab at UIUC is seeking participants for ongoing
Another study conducted by the Alcohol Research Lab at UIUC looks at how social interactions impact drinking behavior, said Jaime Shields, another research coordinator at the lab. Participants go into the lab, drink alcohol and run through a series of social tasks, she said. They are hooked up to an electroencephalogram, or EEG, which measures ...
Parents' watchful eye may keep young teens from trying alcohol, drugs
Study of pre-teens yields surprises about alcohol, tobacco and marijuana Jul 1, 2022 Only 1 in 5 parents plan to get COVID vaccine for kids under 5 when available
A Parent's Watchful Eye Does Keep Kids From Drugs, Alcohol: Study
US News is a recognized leader in college, grad school, hospital, mutual fund, and car rankings. Track elected officials, research health conditions, and find news you can use in politics ...
Changes in alcohol consumption and alcohol problems before and ...
Most past studies examining changes in alcohol use from before to during the COVID-19 pandemic used cross-sectional designs that required participants to retrospectively report on their pre ...
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VIDEO
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The alcohol and addiction research domain criteria (AARDoC) , which have been operationalized in the addictions neuroclinical assessment , focus on the following three domains that correspond to particular phases in the addiction cycle: incentive salience in the binge/intoxication phase, negative emotionality in the withdrawal/negative affect ...
Pathologic alcohol use affects more than 2 billion people and accounts for nearly 6% of all deaths worldwide. There are three medications approved for the treatment of alcohol use disorder by the US Food and Drug Administration (FDA): disulfiram, naltrexone (oral and long-acting injectable), and acamprosate. Of growing interest is the use of anticonvulsants for the treatment of alcohol use ...
Only a small percent of individuals with alcohol use disorder contribute to the greatest societal and economic costs ().For example, in the 2015 National Survey on Drug Use and Health survey (total n = 43,561), a household survey conducted across the United States, 11.8% met criteria for an alcohol use disorder (n = 5124) ().Of these 5124 individuals, 67.4% (n = 3455) met criteria for a mild ...
It is well recognized that alcohol use disorders (AUD) have a damaging impact on the health of the population. According to the World Health Organization (WHO), 5.3% of all global deaths were attributable to alcohol consumption in 2016 [].The 2016 Global Burden of Disease Study reported that alcohol use led to 1.6% (95% uncertainty interval [UI] 1.4-2.0) of total DALYs globally among females ...
For alcohol addiction, meta-analysis of twin and adoption studies has estimated heritability at ~50%, while estimates for opioid addiction are even higher [44, 45]. Genetic risk factors are to a ...
Excessive alcohol use is the cause of an ongoing public health crisis, and accounts for ~5% of global disease burden. A minority of people with recreational alcohol use develop alcohol addiction ...
Gelernter, J. et al. Genomewide association study of alcohol dependence and related traits in a Thai population. ... This research is based on data from the Million Veteran Program (MVP), Office ...
Alcohol, Clinical and Experimental Research provides direct access to the most significant and current research findings on the nature and management of alcoholism and alcohol-related disorders. Read Virtual Issues on key topics in the field of Addiction ... This study reveals that escalating drinking in certain U.S. adult subpopulations is a ...
The numbers for substance use disorders are large, and we need to pay attention to them. Data from the 2018 National Survey on Drug Use and Health suggest that, over the preceding year, 20.3 million people age 12 or older had substance use disorders, and 14.8 million of these cases were attributed to alcohol.When considering other substances, the report estimated that 4.4 million individuals ...
This study examined associations between alcohol outcomes (e.g., alcohol dependence, alcohol-related problem consequences), help-seeking, and treatment satisfaction among a community sample of 722 sexual minority women (SMW) by age, sexual identity, race/ethnicity, and income.
Among adolescents, studies of whether alcohol dependence increases risk of subsequent depression have several limitations, and evidence on frequency and quantity of consumption is inconsistent. ... Another limitation of research on alcohol use and depression among adolescents is that most participants were born during the 1970s or early 1980s ...
About the journal. Drug and Alcohol Dependence is an international journal devoted to publishing original research, scholarly reviews, commentaries, and policy analyses in the area of drug, alcohol and tobacco use and dependence. Articles range from studies of the chemistry of substances of abuse, their actions at molecular and cellular sites ...
The purpose of this study is to evaluate the safety, tolerability and effectiveness of V117957, compared to placebo, in subjects with alcohol use disorder (AUD) who experience insomnia associated with alcohol cessation. Alcohol abuse and dependence remain highly prevalent and disabling. Persistent low treatment rates and high relapse rates ...
Cessation of alcohol use is associated with substantial reductions in depressive symptoms, as demonstrated, for example, in the classic studies of Brown, Schuckit, and colleagues among veterans hospitalized with alcohol use disorder ( 2, 3 ). This suggests a toxic effect of alcohol on depression. DSM-IV and DSM-5 ( 4, 5) introduced the ...
Dr. W. Kyle Simmons — Oklahoma State University Center for Health Sciences professor of pharmacology and physiology — is leading the Semaglutide Therapy for Alcohol Reduction study at OSU's Hardesty Center for Clinical Research and Neuroscience to determine whether semaglutide can be used to treat alcohol use disorder.
While most of our knowledge on the effects of alcohol on the brain and cognitive outcomes is based on research in adults, several recent reviews have examined the effects of alcohol on the brain ...
The Vanderbilt Center for Addiction Research hosted Science Day on April 18. The annual event, which started in 2017, featured the latest research in addiction, including investigations into alcohol, opioids, and stimulants. ... where he studies the neural mechanisms underlying habit formation, ...
Researchers are recommending full-scale human trials after an insomnia drug helped a man withdraw from his 16 drinks-a-day addiction. Minister for Education and Medical Research Hon Ben Carroll ...
Despite an increase in alcohol-related deaths in the US over the last 2 decades, 1,2 little is known about alcohol-related mortality risks among physicians 3 and other health care workers. Compared with non-health care workers, health care workers have increased drug overdose death risks. 4 An occupational liability to substance use or to risks of painful injuries and access to controlled ...
The new study aimed to investigate whether inhibiting CRF-expressing neurons in this region could reduce alcohol consumption in a rat model of comorbid PTSD and AUD, thereby identifying a ...
Episode 22: Donita Robinson, PhD, UNC Department of Psychiatry & Bowles Center for Alcohol Studies May 8, 2024 January & February 2024 Newsletter March 18, 2024 November ... Center for Addiction Research & Education University of Florida Physical Address 1395 Center Dr, Suite D2-013 Gainesville, FL 32610 ...
Another study conducted by the Alcohol Research Lab at UIUC looks at how social interactions impact drinking behavior, said Jaime Shields, another research coordinator at the lab. Participants go into the lab, drink alcohol and run through a series of social tasks, she said. They are hooked up to an electroencephalogram, or EEG, which measures ...
Study of pre-teens yields surprises about alcohol, tobacco and marijuana Jul 1, 2022 Only 1 in 5 parents plan to get COVID vaccine for kids under 5 when available
US News is a recognized leader in college, grad school, hospital, mutual fund, and car rankings. Track elected officials, research health conditions, and find news you can use in politics ...
Most past studies examining changes in alcohol use from before to during the COVID-19 pandemic used cross-sectional designs that required participants to retrospectively report on their pre ...