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  1. Antigen presentation - Wikipedia

    Antigen presentation is a vital immune process that is essential for T cell immune response triggering. Because T cells recognize only fragmented antigens displayed on cell surfaces, antigen processing must occur before the antigen fragment can be recognized by a T-cell receptor. Specifically, the fragment, bound to the major histocompatibility ...

  2. Antigen Presentation - an overview | ScienceDirect Topics

    Antigen presentation is the process whereby antigens are recognized by immunocompetent cells and taken up by antigen-presenting cells (macrophages, dendritic cells, etc.) after processing to be displayed on the surface of peptide-presenting cells [1].

  3. A guide to antigen processing and presentation | Nature ...

    Antigen processing and presentation are the cornerstones of adaptive immunity. B cells cannot generate high-affinity antibodies without T cell help. CD4+ T cells, which provide such help, use ...

  4. Antigen Processing and Presentation - TeachMePhysiology

    Antigen Presentation. Antigens are delivered to the surface of APCs by Major Histocompatibility Complex (MHC) molecules. Different MHC molecules can bind different peptides. The MHC is highly polygenic and polymorphic which equips us to recognise a vast array of different antigens we might encounte

  5. Antigen Processing and Presentation | British Society for ...

    Antigen Processing and Presentation. In order to be capable of engaging the key elements of adaptive immunity (specificity, memory, diversity, self/nonself discrimination), antigens have to be processed and presented to immune cells. Antigen presentation is mediated by MHC class I molecules, and the class II molecules found on the surface of ...

  6. 20.3E: Antigen-Presenting Cells - Medicine LibreTexts

    Antigen presentation is a process in the body’s immune system by which macrophages, dendritic cells and other cell types capture antigens, then present them to naive T-cells. The basis of adaptive immunity lies in the capacity of immune cells to distinguish between the body’s own cells and infectious pathogens.

  7. A guide to antigen processing and presentation - PubMed

    Abstract. Antigen processing and presentation are the cornerstones of adaptive immunity. B cells cannot generate high-affinity antibodies without T cell help. CD4 + T cells, which provide such help, use antigen-specific receptors that recognize major histocompatibility complex (MHC) molecules in complex with peptide cargo.

  8. The known unknowns of antigen processing and presentation

    Antigen processing and presentation is the mechanism by which whole antigens are degraded and loaded onto MHC molecules for display on the cell surface for recognition by T cells. Both macrophages ...

  9. Antigen Presentation - an overview | ScienceDirect Topics

    Antigen presentation is the initial stage of the immune response and is mainly a process in which antigen-presenting cells (e.g., dendritic cells (DCs), macrophages) take up and process them into antigenic peptides so that they can be recognized by immunocompetent cells. Allergologia et Immunopathologia, 2019. About this page.

  10. Antigen-presenting cell - Wikipedia

    An antigen-presenting cell (APC) or accessory cell is a cell that displays an antigen bound by major histocompatibility complex (MHC) proteins on its surface; this process is known as antigen presentation. T cells may recognize these complexes using their T cell receptors (TCRs). APCs process antigens and present them to T cells.