Top five research articles of 2020
Despite the significant challenges this year has posed, The Pharmaceutical Journal has continued to publish high-quality peer-reviewed research.
Our researchers have made a range of investigations — from evaluating pharmacist interventions using the Simpler tool in Malaysia , to a pharmacist-led virtual thiopurine clinic to support people with inflammatory bowel disease and auto-immune hepatitis, here in the UK.
We have some exciting research coming up in 2021, but in case you missed them the first time around, here are the top five most popular research articles of 2020:
5. Misuse of prescription and over-the-counter drugs to obtain illicit highs: how pharmacists can prevent abuse
Use of prescription and over-the-counter drugs for recreational purposes is increasing, and this perspective article collates the existing literature to provide an in-depth overview of the misuse and diversion of a range of drugs with psychoactive potential, including gabapentinoids, antihistamine drugs and loperamide.
4. Effective detection and management of hypertension through community pharmacy in England
Community pharmacists can play a big role in managing hypertension — from the identification of medication-related problems, to providing lifestyle advice. Despite this, they are not routinely involved in structured hypertension management or screening programmes. So, this review summarises the evidence to recommend the roll-out of a community pharmacy-led hypertension management service.
3. Recent advances in the oral delivery of biologics
Oral administration of medicines is often preferred by patients for its convenience, but, for biologics, the gastrointestinal tract poses challenges for administering in this way. This review discusses the advantages and limitations of several novel drug delivery strategies, and highlights the work to be done to put this technology into clinical practice.
2. Immuno-oncology agents for cancer therapy
Immuno-oncology is a novel treatment that works by conditioning the body’s immune cells to recognise and kill cancer cells — combining this treatment with conventional therapies has led to promising improvements in patient outcomes. This review looks at the range of immuno-oncology agents, and how problems such as their toxicity and high cost can be overcome.
1. Investigational treatments for COVID-19
The emergence of COVID-19 resulted in a global research effort to find effective treatment options to relieve healthcare burdens and, ultimately, save lives. In June 2020, this rapid review summarised the clinical trials and treatment evidence at the time.
Check out The Pharmaceutical Journal’ s ‘Everything you should know about the coronavirus outbreak’ for the latest on this continually evolving situation.
Find the full catalogue of articles in our research section .
Call for submissions
In 2021, The Pharmaceutical Journal will keep adding to the evidence base with review, perspective and research articles. If you have undertaken research into innovations and initiatives that can improve pharmacy services and administration, the pharmacological management of disease, or advances in drug development, please submit your article for consideration by email to: [email protected]
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NICE recommends tenecteplase for treating acute ischaemic stroke patients
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Explore JAMA Network Open’s collection on clinical pharmacy and pharmacology, including topics in drug safety and development, pharmacogenetics, and more.
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This cohort study compares the use of immune checkpoint inhibitor therapy with conventional chemotherapy in patients with non–small cell lung cancer (NSCLC) and overweight or obesity.
This qualitative study assesses the quality, amount of active ingredient, and characteristics associated with counterfeiting of semaglutide purchased from illegal online pharmacies without a prescription.
- Building an Evidence Base for Deprescribing in the Setting of Polypharmacy JAMA Network Open Opinion July 30, 2024 Geriatrics Health Care Safety Health Policy Clinical Pharmacy and Pharmacology Full Text | pdf link PDF open access
This randomized clinical trial investigates whether multidisciplinary team-based medication optimization has an effect on survival, unscheduled hospital visits, and rehospitalization among older inpatients with polypharmacy.
This cluster randomized clinical trial tests a health system–embedded deprescribing intervention targeting older adults and their primary care clinicians for reducing the use of central nervous system (CNS)–active drugs and preventing medically treated falls.
- Addressing Undertreatment of Atrial Fibrillation With Community Pharmacists JAMA Network Open Opinion July 24, 2024 Cardiology Health Care Workforce Health Care Delivery Models Health Policy Clinical Pharmacy and Pharmacology Full Text | pdf link PDF open access
This randomized clinical trial compares early and delayed pharmacist intervention for oral anticoagulation therapy among patients with undertreated and newly diagnosed atrial fibrillation in community pharmacies.
This cohort study assesses the association of medication for opioid use disorder (MOUD) initiation after hospitalization or an emergency department (ED) visit with subsequent fatal or nonfatal opioid overdose at 6 and 12 months.
This cross-sectional study examines the rates of method of contraception documentation in the electronic medical record (EMR) for patients receiving 1 of 3 drugs known to be associated with adverse perinatal outcomes.
This case-control study assesses the association between long-term exposure to oral corticosteroids and adverse events among adult patients with atopic dermatitis.
- Access and Safety—The FDA Drug Approval Conundrum JAMA Network Open Opinion July 18, 2024 Health Policy Cardiology Clinical Pharmacy and Pharmacology Health Care Safety Pulmonary Medicine Full Text | pdf link PDF open access
This cross-sectional study examines changes in the use of and liver function test monitoring for ambrisentan and bosentan after changes by the US Food and Drug Administration to the ambrisentan labeling and risk evaluation and mitigation strategy.
- Navigating Drug Interactions with Proton Pump Inhibitors JAMA Network Open Opinion July 9, 2024 Adverse Drug Events Clinical Pharmacy and Pharmacology Gastroenterology Gastroesophageal Reflux Gastroduodenal Ulcer Full Text | pdf link PDF open access
This cohort study examines the association of reaching age 65 years and enrolling in Medicare with out-of-pocket costs and utilization of type 2 diabetes medication.
This cross-sectional study evaluates the consistency between summary of product characteristics and interaction checkers for potential drug-drug interactions with proton pump inhibitors (PPIs).
This nonrandomized trial evaluates whether a 7-day injectable preparation of extended-release buprenorphine is acceptable, well-tolerated, and safe for patients with minimal to mild opioid withdrawal.
This randomized clinical trial assesses the effect of a multispecies probiotic supplement on antibiotic-associated diarrhea among patients aged 18 years and younger who are receiving antibiotics.
- Optimizing the Value of β-Lactam Antibiotics Through Extended Infusion JAMA Network Open Opinion July 2, 2024 Emergency Medicine Infectious Diseases Sepsis Critical Care Medicine Resuscitation Full Text | pdf link PDF open access
This cohort study investigates associations between gender-affirming hormone treatment and development and progression of metabolic syndrome among transgender veterans compared with cisgender veterans.
This cohort study assesses whether extended-infusion β-lactam therapy is associated with survival, adverse events, and/or emergence of resistance in adults with gram-negative bloodstream infections.
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Clinical pharmacology articles from across Nature Portfolio
Clinical pharmacology is a branch of biomedical science. It includes drug discovery, the study of the effects of drugs on their targets in living systems and their clinical use, as well as the study of biological function related to these chemicals. Clinical pharmacology includes application of pharmacological principles, such as pharmacodynamics and pharmacokinetics.
Latest Research and Reviews
Depression clinical trials worldwide: a systematic analysis of the ICTRP and comparison with ClinicalTrials.gov
- Eugenia D. Namiot
- Diana Smirnovová
- Helgi B. Schiöth
JNJ-77242113, a highly potent, selective peptide targeting the IL-23 receptor, provides robust IL-23 pathway inhibition upon oral dosing in rats and humans
- Anne M. Fourie
- Xiaoli Cheng
- Nishit B. Modi
Network pharmacological prediction of the mechanism of action of Shen-Zhu-Lian-Bai Decoction in the treatment of ulcerative colitis
- Jinghua Liang
Analysis of post-market adverse events of tafamidis base on the FDA adverse event reporting system
Investigating clinical pharmacokinetics of brivaracetam by using a pharmacokinetic modeling approach
- Attia Qayyum
- Ammara Zamir
- Faleh Alqahtani
A meta-analysis of the effects of ketamine on suicidal ideation in depression patients
- ZuoYao Shen
- DaiQuan Gao
News and Comment
Dual SGLT1 and SGLT2 inhibitor sotagliflozin achieves FDA approval: landmark or landmine?
The US Food and Drug Administration (FDA) has approved sotagliflozin with a broad heart-failure indication, even in the absence of trial data in patients without diabetes. No one knows what the benefits or risks of inhibiting SGLT1 in the heart might be.
- Milton Packer
Inaxaplin for the treatment of APOL1 -associated kidney disease
APOL1 risk variants are associated with an increased risk of chronic kidney disease. Findings from a new study demonstrate that a small molecule, inaxaplin, inhibits APOL1 channel function; furthermore, inaxaplin reduced proteinuria in patients with focal segmental glomerulosclerosis and two APOL1 risk variants.
- Rasheed Gbadegesin
- Brandon Lane
Targeting drug-resistant mutations in ALK
Therapy resistance limits the clinical success of tyrosine kinase inhibitors (TKIs) in ALK-positive non-small cell lung cancer. A study now proposes a framework to identify compound resistance mutations to the lorlatinib TKI and provides structure-based drug design approaches to overcome resistance mediated by ALK(G1202R) or ALK(I1171N/S/T).
- Arvin C. Dar
Nanocapsule system tackles polymyxin B toxicity
- Monica Wang
Potential cardiorenal benefits of efpeglenatide in diabetes
Building on previous cardiovascular outcome trials with glucagon-like peptide 1 receptor agonists, the AMPLITUDE-O trial reported significant improvements in major adverse cardiovascular and kidney outcomes with efpeglenatide in type 2 diabetes. A longer-term trial with dose-dependent analysis on kidney outcome components will better define the effects of efpeglenatide in the diabetic kidney.
- Mark E. Cooper
The role of steroids in treating diabetic macular oedema in the era of anti-VEGF
- Tamir Weinberg
- Anat Loewenstein
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- Potential Research Projects
Research projects for Higher Degree by Research (HDR) students are available within the following School of Pharmacy research areas and research centre.
Please email our academic staff to discuss potential HDR projects and ask if they are available as an advisor for your proposed HDR program.
Clinical Pharmacy and Pharmacometrics
Title: Implementing Pharmacogenomics into Community Pharmacy Practice to Personalise the Treatment of Depression Contact: Associate Professor Chris Freeman
Title: Developing pharmacokinetic models for immunosuppressants in solid organ transplant patients Contact: Dr Christine Staatz
Title: Improving the use of immunosuppressant agents in solid organ transplant patients Contact: Dr Christine Staatz
Medication Use, Safety and Health Services Research
Title: The ethics of pharmacogenomic testing in community pharmacy Contact: Doctor Adam La Caze
Title: Pharmacy ethics and the opioid crisis Contact: Doctor Adam La Caze
Title: Improving the use of immunosuppressant agents in solid organ transplant patients Contact: Dr Christine Staatz
Title: Establishing pharmacokinetic and pharmacodynamic models for antibiotics used in special paediatric populations Contact: Dr Christine Staatz
Title: Queensland Family Cohort (QFC) : Characterising medication usage within the perinatal-postnatal family environment Contact: Dr Meng-Wong Taing
Title: Pharmacy and oral healthcare Contact: Dr Meng-Wong Taing
Pharmacoepidemiology, Pharmacovigilance and Pharmacoeconomics
No projects currently available.
Biotherapeutic Delivery and Diagnostic Solutions
Title: Computer-aided design, synthesis and evaluation of targeted drug delivery systems Contact: Dr Ben Ross
Title: Engineering peptides and proteins as therapeutics Contact: Dr Peter Moyle
Title: Improving the delivery characteristics of protein / peptide drugs Contact: Dr Peter Moyle
Title: Deciphering the roles of post-translational modifications Contact: Dr Peter Moyle
Title: Recombinant, semisynthetic and synthetic vaccines Contact: Dr Peter Moyle
Title: Targeted delivery systems for RNAi and DNA delivery Contact: Dr Peter Moyle
Title: Enhancing the activity of antimicrobial agents Contact: Dr Peter Moyle
Title: Engineering nanostructures and nanomedicines using supercritical fluid technology Contact: Dr James Falconer
Title: Improving delivery of challenging to formulate bioactives using advanced delivery systems Contact: Dr James Falconer
Title: Discovery of new drugs from indigenous Australian plants using supercritical fluids Contact: Dr James Falconer
Title: Design, construction, and development of supercritical fluid technology Contact: Dr James Falconer
Title: Characterisation of high pressure spray behaviour and bioactive Contact: Dr James Falconer
Title: Delivery of therapeutics to the posterior eye Contact: Dr Harendra Parekh
Title: Development of bioresponsive drug/gene carrier systems Contact: Dr Harendra Parekh , Dr Karnaker Tupally
Title: Bioresponsive porous silicon-polymer composite nano- and micro-particles for oral protein delivery Contact: Dr Amirali Popat
Title: Mesoproous silica nanoparticles synthesis and application in drug delivery, diagnosis and therapeutic protein delivery Contact: Dr Amirali Popat
Title: Inorganic nanoparticles for targeting bacterial biofilms Contact: Dr Amirali Popat
Pharmaceutical Biology
Title: Calcium homeostasis in cancer: identification and characterisation of novel drug targets Contact: Professor Greg Monteith and Professor Sarah Roberts-Thomson
Title: Identification and characterization of novel ion and drug transporters and the design of novel high throughput screening assays for new pharmaceuticals Contact: Professor Greg Monteith
Title: Physiological regulation and the role of calcium transporters Contact: Professor Greg Monteith
Title: Morphine and metastasis Contact: Associate Professor Marie-Odile Parat
Title: Role of caveolar proteins in glioblastoma Contact: Associate Professor Marie-Odile Parat
Title: Effect of perioperative pharmacotherapy of cancer patients on tumour Biology Contact: Associate Professor Marie-Odile Parat , Dr Ben Ross and Professor Nick Shaw
Biomedicinal Discovery and Development
Title: Design, synthesis and evaluation of novel molecules for the treatment of Alzheimer's disease Contact: Dr Ben Ross
Title: Computer-aided design, synthesis and evaluation of new drugs for cancer, pain and neurodegenerative diseases Contact: Dr Ben Ross
Pharmacy Education Research Centre
No current projects available.
Alan Grant-Taylor Memorial Scholarship: Community Pharmacy Practice
Find out more about the Alan Grant-Taylor Memorial Scholarship
UQ Summer and Winter Research Programs
Coordinated by the UQ Student Employability Centre, these programs provide an opportunity for scholars to work with a researcher in a formal research environment in their area of interest.
By participating in a program students will gain valuable academic and professional opportunities, develop analytical, critical thinking, and communication skills, and have an opportunity to cultivate links with industry and academic contacts.
It is also a chance to ‘test drive’ research before embarking on further research studies or higher degree research projects. Participation is open to undergraduate students and Masters by coursework students.
All students participating in the summer and winter programs will receive a scholarship. General information on the program, including how to apply, is available from the UQ Student Employability Centre’s program website .
Please see our Summer and Winter Research Program page for a full list of the available programs.
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51 Research topics related to Pharmacy
- November 26, 2022
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Looking for research topics related to Pharmacy? this page might help you come up with ideas. Research topics are subjects or issues researchers are interested in when conducting research. A well-defined research topic is the starting point of every successful research project. Choosing a topic is an ongoing process by which researchers explore, define, and refine their ideas.
There are many research topics related to Pharmacy , depending on your specializations and interests. The topics below are only for guides. We do not encourage writing on any of them because thousands of people visit this page to also get an idea of what topics to write on.
Pharmacy is the science and practice of discovering, producing, preparing, dispensing, reviewing and monitoring medications, aiming to ensure the safe, effective, and affordable use of medicines The main purposes of research topics related to Pharmacy are to inform action, gather evidence for theories, and solutions to problems, and contribute to developing knowledge.
- A Pharmaceutical Equivalence Study Of The Selected Azithromycin Mg Brands On The [Country] Market
- A Study Of Treatment And Management Procedures Of Peptic Ulcers In Hospitals In [Country]
- Assessment On Analysis Of Water Pollution By Phosphate
- Availability And Storage Of Vaccines In Community Pharmacies
- Antibiotic Sensitivity Patterns Of Staphylococcus Aureus To Methillicin In Clinical Samples At…
- Antihyperlipidemic And Antioxidant Effects Of Phaseolus Vulgaris In [Country]
- Antimicrobial Activity Of Methanol Extract And Fractions Of Moringa Oleifera Lam.
- Assessing Undergraduate Students’ Motivation To Study Pharmacy, Attitudes And Future Career Professional Choices In Universities Of …..
- Assessment Of Knowledge, Attitudes And Practices Of Pharmacovigll, Ance Among Health Care Practitioners At The ….. Hospital
- Assessment Of Quality Of Metronidazole Tablet Brands Sold In Pharmacies In [Location].
- Assessment On Analysis Of Water Pollution By Phisphate In The [Location]
- Assessment Of Effective Use Of Anti-Epileptic Drug Therapy Among Patients At [Location]
- Assessment Of Health Workers’ Adherence To Standard Treatment Guidelines In the Management Of Typhoid Fever At [Location]
- Assessment Of The Chemical Composition And Pesticide Properties Of Cassia Didymobotrya Ash On Myzus Persicae Affecting Tomato Crops In [Location]
- Assessment Of The Quality And Dissolution Profiles Of Branded Fixed Dose Artemetherilumefantrine Tablets Sold At Pharmacies In [Location]
- Availability And Storage Of Vaccines In Community Pharmacies In Some Selected Communities In [Location]
- Determination Of The Microbial Contamination Of Disinfectant And Antiseptic Produced In [Location]
- Determining The Recreational Health Practices By Pregnant Women In Selected Antenatal Clinics
- Development And Validation Of Spectrophotometric Methods For The Determination Of Risperidone In Pure And Tablet Dosage Forms
- Drugs Use Practices In Fako Division: A Case Study Of [Location]
- Estimation Of The Effect Of Cisampelous Owanrensis Benzene Fraction On Glucose Absorption Across The Intestinal Epithelium Of Wister Rats On Aloxan-Induced Diabetes
- Evaluation Of Antibreast And Antiprostate Cancer Activities Of Selected Medicinal Plants From Some Parts Of [Location]
- Factors Affecting Prevalence Of Self Medication Of Antibiotics Among Adult Population In [Location]
- Hypoglycemic Effects Of Sonchus Oleraceus (Moleta) In Normal Albino Rats
- Investigating The Presence Of Staphylococcus Aureus And Escherichia Coli In Dairy Products
- Investigation Of The Social And Economic Impact And Consequences Of Chronic Diseases On Low Income-Earning Family
- Isolation Of Microorganism Associated With Deterioration Of Bananas Fruits
- Inorganic Pollutants In Drinking Water In Mamfe Municipality: Implications On Water Safety And Cancer Risks For The Inhabitants
- Isolation And Identification Of Bacteria Associated With Wound Sepsis
- Isolation Of Microorganisms Associated With Deterioration Of Bananas Fruits In Buea Municipality
- Pharmacoeconomic Analysis Of Hiv/Aids Management Pharmacy
- Pharmacy Project Topics And Materials
- Phytochemical And Antimicrobial Analysis Of Mystetoe Leaves
- Preliminary Phytochemical And Antimicrobial Screening Of Flower And Stalk Of Mangifera Indica (Opioro Mango)
- Preliminary Phytochemical And Antimicrobial Screening Of Seed And Coat Of Citrus Sinensis
- Production Of Mosquitoes Repellants Insecticides (Mosquito Coil) Using Orange Peels (Cestrum)
- Profile Of Antibiotic Use At The Health Centre
- Pharmacoeconomic Analysis Of Hiv/Aids Management Pharmacy In Limbe Municipality
- Prevalence, Treatment, And Gametocyte Carriage In Children With Malaria At [Location]
- Profile Of Antibiotics Use At [Location]
- Recycling Waste Polyethylene Materials To Useful Products Via Pyrolysis
- Reviewing The Nutritional And Pharmacological Importance In Common Vegetables In [Location]
- The Causes And Effects Of Cholera Among Children
- The Effect Of Cisampelous Owarensis Benzene Fraction On Glucose Absorption Across The Intestinal Epithelium Of Wister Rats On Aloxan-Induced Diabetes
- The Use Of Quality Control Parameters In The Evaluation Of Vegetable Crude Drugs
- Working Capital Management And Profitability Of Listed Pharmaceutical Firms In [Location]
- Wound Healing And Anti-Inflammatory Activities Of Ceiba Pentendra (L.) Gaertn In Guinea Pigs
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Pharmacy Student Research Projects
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ABOUT THE COLLECTION
All PharmD students at the University of Arizona College of Pharmacy must complete a research project as part of their graduation requirements. This repository collection contains the abstracts of these projects, and the full-text of projects that students have opted to make available.
Contact Jennifer Martin , Librarian & Clinical Instructor, Pharmacy Practice and Science, for more information about the student research projects in this collection.
Recent Submissions
Exploring How to Improve Professionalism and Engagement During Zoom Learning
A retrospective study evaluating the effect of hepatic steatosis on paclitaxel tolerability in patients with breast cancer
Accuracy and Reproducibility of Injections from Prefilled “Code Cart” Syringes Compared to Standard Polypropylene Syringes
Modified Patient Intake Process and its Effectiveness in Timely Access to Patient Data in Endocrinology Telemedicine Visits
The Role of Vaccine Literacy on Vaccination Rates in Maricopa County Health Pods
Assessing community pharmacists’ confidence with and knowledge of veterinary medications
Implementation and Review of Student Led Meds-to-Beds Intervention on Hospital Readmission Rates and Patient Satisfaction in Advanced Heart Failure
Assessing knowledge and integration of updated FDA pregnancy and lactation labeling in practice between rural and urban prescribers and dispensers
Surveying rural healthcare workers for vaccine awareness and hesitancy
Perceived Mental Health of Student Pharmacists Working in Community Settings During the Coronavirus Disease-19 (COVID-19) Pandemic: A Qualitative Analysis at the University of Arizona College of Pharmacy
Do Rural And High Index Of Need Counties Have Different COVID-19Vaccination Rates?
A Pilot Educational Video Series Aimed at Orienting Non-Native English Speakers to the U.S. Pharmacy System
Prophylactic Benzodiazepine Use in Bupropion Overdose
Comparison of Inhaled Epoprostenol and Inhaled Nitric Oxide for COVID-19 Induced ARDS in Critically Ill Adults
A Qualitative Analysis of 2022 Request to Speak Comments
Impact of Student Loan Debt on University of Arizona R. Ken Coit College of Pharmacy Alumni
Outcomes of patients with DKA treated with subcutaneous insulin in the emergency department
Identifying the Student Pharmacists’ Perception of Characteristics of a Fulfilling Career
Anticoagulation Quality Assessment and Risk Evaluation in Patients with Nonvalvular Atrial Fibrillation (NVAF)
Influenza Vaccination Perceptions Among Pharmacy Students During the COVID-19 Pandemic
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Pharmacy Research Topics
Research Topic Ideas for Biology
Pharmacy research ideas encompasses a variety of topics dealing with drugs and pharmaceuticals. Some broad areas of pharmaceutical research relate to drug delivery, pharmaceutical cell biology, medicinal chemistry and medicine management. Faculty and graduate students at pharmaceutical colleges typically engage in such research, and some go on to develop new drugs and delivery methods.
TL;DR (Too Long; Didn't Read)
For students pursing doctorate degrees, pharmacy research offers many topics for a thesis, such as developing new drugs for cancer treatments, drug delivery methods, pharmaceutical cell biology and medicine management. Other topic ideas include plants as a source of medicinal products, interaction of drugs with RNA, synthetic medicines and many more.
Cancer Drug Studies
Cancer drug studies represent one type of pharmacological research topic. For instance, researchers study the role of steroid drugs in the growth of breast cancer. Other topics include the development of new cancer therapies and using targeted approaches for drug delivery to treat cancer. These types of studies aim to help patients deal with cancer and better handle the effects of cancer.
Drug Delivery
Another major topic for pharmacy research relates to drug delivery. One such research study at looks at the design and evaluation of drug delivery systems, emphasizing some methods of delivery such as liposomes and liquid crystals. Another research project studies the immediate environment of the lung, particularly how a person reacts to inflammatory stress and the use of drug treatments. Investigators use human lung epithelial cell culture for the study, studying humans as well as animals.
Pharmaceutical Cell Biology
Research in the area of pharmaceutical cell biology aims to understand basic cell biology and relate the findings to diseases in humans. Some such research projects in this area have dealt with topics such as inflammation processes in human disease, mechanisms for cell-to-cell communications and mechanisms of carcinogenesis. This sort of research is likely to involve close work with biologists who have similar research interests in these sorts of topics.
Medicine Management
Medicines management research looks into the cost effectiveness of new interventions that aim to improve the health of patients. Some of this research focuses on older people and on mental illness along with medicine management. These topics deal with the evaluation of pharmacist-led services, interventions that improve the adherence of medications, consultation skills, medication review services and interventions for reducing the problems that come about as a result of dysphagia.
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Encouraging dissemination of research on the use of artificial intelligence and related innovative technologies in clinical pharmacy practice and education: call for papers
- Published: 24 July 2024
- Volume 46 , pages 777–779, ( 2024 )
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- Kreshnik Hoti 1 &
- Anita Elaine Weidmann 2 , 3
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The rapid evolution of artificial intelligence (AI) and related innovative technologies has recently taken the world of science by storm [ 1 , 2 , 3 ]. Considering challenges involved during transition from conceptual and research stages and then clinical practice implementation, the integration of this easy to access technology into clinical pharmacy practice and research has since caused extensive debate as well as innovative curiosity [ 4 , 5 , 6 ]. While its implications are yet to be fully understood, the opportunities to enhance patient care, optimize therapeutic outcomes, and advance research seem unprecedented [ 7 , 8 ].
A review in the New England Journal of Medicine proposes that machine learning is not just a new tool, but a fundamental technology required to meaningfully assist with the delivery of the best possible patient care [ 9 ]. Machine learning driven clinical decision support systems (CDSS) based on electronic health records are tested for use in predicting patient outcomes [ 10 ], personalizing treatment plans, identifying adverse drug reactions [ 11 , 12 ], predicting potential medication-related problems before they occur [ 13 ] and assisting pharmacy professionals with real-time, evidence-based recommendations [ 14 , 15 ]. In Industry, AI enabled solutions are increasingly being used to automate, optimize and personalize anything from drug discovery to drug dispensing [ 16 ]. Automated systems can assist in drug dispensing and monitoring adherence [ 17 , 18 ], whereas AI-enabled solutions have been proposed to evaluate medication administration, as a key component that could assist health professionals to promote medication adherence [ 19 ]. Issues such as medication adherence have long been central to pharmacy professionals’ endeavors focused on improving patients’ outcomes [ 20 , 21 , 22 ]. Mobile health applications, on the other hand, promise to empower patients with tools to manage their medications, track their health metrics, and communicate with their healthcare providers, fostering a more collaborative and patient-centered approach to healthcare [ 23 ]. They can speed up and simplify history taking [ 23 ], improve pharmacovigilance [ 24 ], as well as monitor personal analytics, physical status, and physiological parameters [ 25 ]. Additionally, the development of various machine learning techniques is unlocking the potential of big data in healthcare. Some of the key pharmacy related areas, such as medication adherence, are being affected and set to benefit from data mining and capabilities related to big data analytics [ 26 ]. Whilst we continue to understand the power and opportunities pertaining to analysis of big data and subsequent data-driven clinical decision making, unique challenges related to data mining, storage and sharing in healthcare related fields must also be acknowledged and addressed [ 27 , 28 ].
One of the areas that has drawn significant attention recently is also the emergence of large language models (LLM). Various LLM based models are starting to be used across a number of health-related fields. One of the drivers for development of LLM based applications is the availability of massive volumes of text information, which can be used for training LLM based models [ 29 ]. Pharmacy as a field is no exception to this LLM related accelerated innovation considering opportunities for improvement in research related work as well as clinical, academic and educational areas that applies in general to medical related fields [ 4 , 30 ]. In this regard, we have seen a number of works evaluating chatGPT performance related to assessing clinical pharmacy-based knowledge with promising results [ 31 , 32 , 33 ]. Whilst leveraging the potential of LLM models in improving effectiveness and efficiencies of various processes in healthcare and pharmacy specifically, one should also consider ethical use of these transformational technologies. This is especially relevant when it comes to their potential for inaccuracies, spread of misinformation and ensuring responsible use focused on supporting humans rather than replacing them [ 34 ].
Another area worth consideration is the role of AI in education. As institutions are developing mechanisms to integrate AI into curricula, pharmacy programs in general and clinical pharmacy specifically will also undoubtedly feel these innovative changes [ 4 ]. Initial research shows promising results, although further validation is required. For example, potential for improvements in provision of communication training in pharmacy has been evidenced [ 35 ]. Additionally, facilitating patient education through AI-generated content in clinical pharmacy setting has been explored as well as the potential role of AI for replacing traditional formats of learning [ 36 , 37 ]. Nonetheless, there is still a paucity of literature evaluating innovations that are focused on applying AI-based solutions in pharmacy education. Therefore, more research is needed to better understand how AI-based innovations are best integrated in pharmacy education.
As we continue to explore and integrate AI and novel technologies into daily clinical pharmacy practice, research and education, it is imperative to consider the ethical and regulatory challenges they pose [ 38 ]. Issues such as data privacy, algorithmic bias, and the need for rigorous validation of AI tools must be carefully considered to ensure that the benefits are maximised without compromising patient safety and trust [ 39 ]. These developments and considerations are set to have an important impact on the pharmacy profession in general and clinical pharmacy practice and research in particular.
With the above in mind, we dedicate the next special issue of the International Journal of Clinical Pharmacy to reporting AI-based solutions and other related cutting-edge technologies in clinical pharmacy practice and research. We now call for submissions on innovative approaches and ethical stewardship to help promote clinical and practice excellence. This includes the use of any innovative technologies to support clinical decission making and other practice processes, the facilitation of service implementation, new ways of working as well as its use to facilitate research and education and training of the pharmacy team. In an area currently undergoing rapid development and progress, broad dissemination of related work is critical. Ultimately, this will help and better equip pharmacy practitioners, both in research and practice, to better deal with opportunities and challenges that come from these transformative changes for our profession. We believe that by encouraging reporting and sharing of results in this area, not only will we better understand how to best apply AI innovative technologies into clinical pharmacy and research but we will also collectively contribute towards ensuring that pharmacy profession in general is at the frontline of the AI ‘revolution’. This will also help to raise the profile of the profession across the landscape of scientific publishing [ 40 ]. Any papers reporting on the use of AI or innovative technologies that meaningfully assist with the delivery of the best possible patient care through pharmacy related services and solutions are welcome.
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Division of Pharmacy, Department of Pharmacy Practice and Pharmaceutical Care, Faculty of Medicine, University of Pristina, Prishtina, Kosovo
Kreshnik Hoti
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Hoti, K., Weidmann, A.E. Encouraging dissemination of research on the use of artificial intelligence and related innovative technologies in clinical pharmacy practice and education: call for papers. Int J Clin Pharm 46 , 777–779 (2024). https://doi.org/10.1007/s11096-024-01777-z
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DOI : https://doi.org/10.1007/s11096-024-01777-z
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What is Pharmacy Research?
The question of what constitutes pharmacy research emerged at a recent meeting to discuss a pharmacy resident’s project. The pharmacists around the table were attempting to clearly define this seemingly straightforward term in the context of a residency project surveying hospital pharmacists about “pharmacy research”. Surprisingly, this “obvious” term could not be consistently defined by any of the members present, most of whom were well versed in this type of research. This event triggered a lengthy search to define the enigma called “pharmacy research”.
One of our first stops was the Merriam-Webster dictionary. As expected, we did not find the specific term “pharmacy research” in the dictionary. However, a subsequent search for the individual words revealed the following 1 :
Pharmacy: the art, practice, or profession of preparing, preserving, compounding, and dispensing medical drugs Research: studious inquiry or examination; especially: investigation or experimentation aimed at the discovery and interpretation of facts, revision of accepted theories or laws in the light of new facts, or practical application of such new or revised theories or laws
While combining these definitions yields a broad definition, it is limited by the traditional definition of “pharmacy” that the dictionary provides. However, some may consider “pharmacy research”, as defined by this combination of definitions, to be synonymous with the more modern term “pharmacy practice research”. The Canadian Pharmacists Association (CPhA) defines pharmacy practice research as a component of health services research that focuses on the assessment and evaluation of pharmacy practice. 2 While this definition is clearly unique to the profession, not all research in which pharmacists are involved reflects their practice, nor can it solely reflect the practice of pharmacists, especially in the era of collaborative practice teams. Additionally, research done by pharmacists may address important questions that facilitate improved patient care or service delivery, without specifically advancing pharmacy practice, but still contributing to the scientific literature as a whole. The Canadian Institutes of Health Research (CIHR) lists health services research, which includes the efficiency and effectiveness of health professionals, as 1 of its 4 pillars of health research (the others being biomedical; clinical; and social, cultural, environmental, and population health). 3 However, limiting “pharmacy research” to pharmacy practice research limits the impact and relevance of pharmacists’ work to the other CIHR pillars of research deemed to be important to Canadians.
To further refine our definition, we looked to the literature and leading Canadian and US pharmacy organizations for additional insight. An Internet and literature search provided little help with our dilemma. While generally advocating and supporting research, none of these organizations—specifically the CPhA, the Canadian Society of Hospital Pharmacists (CSHP), the American College of Clinical Pharmacy (ACCP), and the American Society of Health-System Pharmacists—have clearly defined pharmacy research. However, both the CSHP and the ACCP have attempted, at least in part, to define “research”.
CSHP has published 2 papers discussing institutional pharmacy research, a statement (published in 1995) 4 and a set of guidelines (published in 1997) 5 . The 1995 statement 4 loosely states that “any unknown in the practice field is a potential research idea” and includes the following as research topics for institutional pharmacists:
- basic pharmaceutical sciences, including the development and testing of new dosage forms or medication-administration modalities
- clinical research concerning the efficacy, safety, and pharmacokinetics of drugs
- pharmacy practice research addressing various issues such as the evaluation of new and existing services, workload measurement, pharmacoeconomics, and quality management
The 1997 guidelines 5 are just as vague and incomplete. They state that “the term ‘research’ can be used to describe many endeavours in institutional pharmacy practice” which may include literature reviews, descriptive studies, and hypothesis-driven research. Neither of the CSHP documents provides the reader with a clear definition of pharmacy research, even though this term is used in the title of both documents. These documents are currently being revised, and we hope that these ambiguities will be addressed.
The ACCP has defined clinical pharmacy as “that area of pharmacy concerned with the science and practice of rational medication use”. 6 This definition offers a more contemporary perspective of pharmacy. The ACCP further defines clinical research as “studies of human subjects, including surveys, cross-sectional studies, case-series, case–control studies, cohort studies, first-in-human studies, proof-of-principle projects and all phases of clinical trials”. 7 By marrying these definitions (which do not appear in the same document), we can create a broad definition of clinical pharmacy research. However, it is likely intentional that these 2 terms were not presented in a single document, as the ACCP is advocating for increased pharmacist participation in all types of clinical research, not just practice-based research. 8
It is clear that while we continue to use the term “pharmacy research”, it carries no universally accepted meaning. As our group discovered, there is far too much ambiguity related to this term. Perhaps we should consider abandoning it.
Perhaps we also need to re-examine our approach to research as a profession. Instead of undertaking so-called ”pharmacy research”, we should follow the lead of our US counterparts and develop a system of pharmacist-researchers and scientists and describe research as any research activity done by pharmacists, regardless of the topic. As health care professionals, pharmacists represent only one aspect of the complex and interdependent health care system. Focusing our energies and resources solely on studying the practice of pharmacy may or may not help in developing our practice, but it will likely add little to the entire health care system. Pharmacists must be involved in all aspects of health research, from basic laboratory investigations to population-based studies. Our unique set of skills and our focus will ensure that we have distinctive research topics. Limiting our contributions to the pillars of health services and clinical research represents a disservice to the advancement of pharmacy and to Canadians.
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2024 KEYS Interns Partner with RKCCOP Faculty for Research Showcase
High school students selected for the KEYS internship presented to over 400 attendees at the 2024 Research Showcase on July 19, in the Health Sciences and Innovation Building. The internship, held annually since 2007, is an opportunity for Arizona students to immerse themselves in scientific projects and training on a practical and real-world scale, under the guidance of University of Arizona faculty members. The program aims to prepare students to pursue STEM degrees after high school while increasing the talent and diversity at in-state universities. We spoke to four students to learn more about how the KEYS internship impacted their academic and professional careers, and the takeaways from their R. Ken Coit College of Pharmacy mentors.
Aleena Rafiyath
“My lab experience was quite inspiring and engaging, as I performed hands-on experiences I never had the chance to work on before,” said Aleena Rafiyath, mentored by Dr. Jason Karnes and Dr. Kasturi Banerjee for her project Detection of association of PHIP gene Copy Number Variation with Warfarin Dose in a Hispanic & Latino Population . “I performed PCR and those experiments that I only learned on paper at school.”
Benite Luhando, who presented The Role Of Cytoskeleton Regulator RNA in Ewing Sarcoma under the guidance of Ajibola Adelakun and Dr. Jacob Schwartz, said of the internship, “I had the opportunity to immerse myself in various molecular biology techniques, such as pipetting, culturing cells, isolating RNA, cDNA synthesis, and quantitative PCR. These hands-on experiences not only deepened my technical knowledge but also enhanced my understanding of the research process.”
Benite Luhando
In addition to the benefits of moving from a classroom to a lab setting, Rafiyath and Luhando also highlighted the connections made while interning. “Participating in this program opened up an opportunity for me to not only make new friendships and establish connections but also explore what to continue in the future,” Rafiyath said. At this year's Research Showcase, 59 students traveled from 31 Arizona high schools to present their work, emphasizing the growing community of KEYS graduates, which now consists of 746 students. Luhando added that the experience of working with professionals and fellow interns “fostered a collaborative and inspiring environment that encouraged learning and growth.” When asked about her post-KEYS journey, Luhando said “This experience has bolstered my confidence in conducting research and presenting scientific findings. I am excited to continue my academic journey with a strong commitment to contributing to the scientific community.”
Emanuele Saladini
For Emanuele Saladini, presenting The Role of Sleep and Cardiovascular Health in Cognitive Impairment and mentored by Dr. Bonnie LaFleur, this internship helped refine his approach to the scientific and research processes. “I particularly appreciate the feedback that helped me apply software engineering principles to my coding work,” he said of his experience working with Coit College of Pharmacy faculty mentors. “Sometimes, research leads to unexpected results, opening an avenue for new hypotheses, and building the foundation for innovation and discovery. The interdisciplinary approach of this program has taught me to work in a team where diverse skills are combined to extract groundbreaking conclusions.”
Aamuktha Tirupati
The opportunities offered by the KEYS internship don’t stop in the lab. After the showcase, Aamuktha Tirupati (presenting What Causes Brain Function to Decline Quickly in the Elderly? , also under Dr. LaFleur) commented on the experience of preparing her findings for the hundreds of attendees: “My experience as a KEYS Intern allowed me to grow professionally and be more prepared for my career. I also gained immense knowledge in R studio and how to effectively communicate my findings to an audience.” Saladini seconded this observation, and added “The ability to communicate complex ideas to various audiences has prepared me for undergraduate research and further professional challenges.”
We want to offer our warmest congratulations to all who participated in the KEYS Research Showcase, a special thanks to the students who discussed their internship experiences with us, and to all of the faculty and KEYS staff who made these opportunities possible. To learn more about the showcase and view the photos, read the full article on the KEYS website .
- Pharmacy Federal Grant to Propel Vaccine Technology Research
Researcher seeks to streamline vaccine manufacturing
OXFORD, Miss. – The U.S. Food and Drug Administration has awarded some $500,000 to University of Mississippi pharmacy professor Mo Maniruzzaman, with a recommendation for another $500,000 in 2025, to develop a technology that promises to streamline vaccine production.
Maniruzzaman, chair of the UM Department of Pharmaceutics and Drug Delivery , will work with two doctoral students and two postdoctoral research fellows to develop a method for manufacturing complex vaccines made with special proteins, referred to as recombinant protein vaccines.
The team will use bacteria or yeast cells that have been engineered to produce recombinant protein vaccines. These proteins, such as hemagglutinin, can protect against the flu or other illnesses.
Shao 'Kenneth' Feng, a first-year doctoral student in pharmaceutical sciences, cultures bioengineered strains of yeast in a petri dish in Mo Maniruzzaman's laboratory in the Thad Cochran Research Center. These yeasts can produce recombinant protein vaccines on demand. Photo by Thomas Graning/Ole Miss Digital Imaging Services
"This technology will change the game when it comes to producing these protein vaccines on demand or at the point of service and is supported by a state-of-the-art approach – a step forward to the existing manufacturing techniques," Maniruzzaman said.
A more streamlined process such as this could, for example, drastically speed up the production of vaccines during flu season or enable the science community to respond more quickly to another pandemic.
Researchers have demonstrated that vaccines produced by these single-cell micro-organisms have great potential to protect against other emerging infectious diseases.
The technology for delivering the vaccine is called sprayed multi adsorbed-droplet reposing technology, or SMART, Maniruzzaman said.
"The need for efficient technology for manufacturing vaccines on demand and at the point of service has never been so pressing as in the midst of the recent pandemic outbreak," he said. "Our lab will broaden the scope of novel 3D printing technology, SMART to single-step manufacturing of biologics, including monoclonal antibodies and protein vaccines."
The biomanufacturing industry is overloaded with processes that are lengthy, expensive and lack flexibility, Maniruzzaman said. Once optimized, his method could be used in large-scale fermentations to produce recombinant protein vaccines on demand and much faster.
"Since COVID rates are predicted to be increasing and flu rates remain particularly high, we need better technologies and treatment mechanisms to highlight how these diseases and their emerging variants work," said Andrew Yockey, epidemiologist and assistant professor in the UM Department of Public Health .
Navya Nalajala a first-year doctoral student in pharmaceutical sciences, works with a 3D SMART printer in Mo Maniruzzaman's lab. Photo by Thomas Graning/Ole Miss Digital Imaging Services
"This technology has the potential to further investigate the complex mechanisms between different types of vaccines and infectious diseases, like COVID and flu, and inform treatment mechanisms."
Maniruzzaman hopes to use SMART to produce polymeric microcarriers – tiny polymer beads that contain bioengineered one-cell organisms, such as yeast or bacteria, into the body. This method offers precise control over the shape and size of the beads to ensure they deliver the vaccine or protein therapeutics where they are needed.
These bioengineered microorganisms will also be capable of producing a range of small-molecule drugs as well as biological medical products, or biologics, such as proteins, antibodies and enzymes, in addition to recombinant protein vaccines.
The technology also could help significantly improve access to vaccines in remote areas where getting them in a timely manner is difficult.
The SMART technology has the potential to improve flexibility, cost and efficiency in manufacturing processes for protein-based biologics that can be used against emerging infectious diseases. It would also mean lower costs to both the consumer and the manufacturer.
A 3D SMART printer deposits tiny beads loaded with vaccine compounds into a vial in Maniruzzaman's lab. Photo by Thomas Graning/Ole Miss Digital Imaging Services
Maniruzzaman began working on this technology while working at the University of Texas. The FDA provided roughly the same funding for his work there, also under the Research Project Grant program.
In recent studies, he and his Ole Miss research team have successfully used the SMART platform to streamline the production and study of how efficiently plasmid DNA demonstrates a response to cancer cells. The results indicate the consistency of the team's technology and potential usage in commercial applications.
"By the end of this project, we envision to develop a state-of-the-art streamlined technology to produce recombinant protein vaccines in a single step and at the point of service," he said. "There's a growing need for distributed manufacturing of biologics-based therapeutics across the world and results obtained from our research will get us one step closer to meet that need.
"This work will also form a strong background for our ongoing efforts of producing mRNA vaccines and therapeutics on demand."
This project is supported by the Food and Drug Administration of the U.S. Department of Health and Human Services as part of a financial assistance award 7R01FD007456-04 totaling $498,119 with 100% funded by the FDA/HHS. The contents are those of the author(s) and do not necessarily represent the official views of, nor an endorsement, by the FDA/HHS or the U.S. government.
See more photos from Mo Maniruzzaman's vaccine technology project
Natalie Ehrhardt
Office, Department or Center
June 17, 2024
- School of Pharmacy
- Research News
SMART Vaccine Technology Project
Mo Maniruzzaman (center), chair of the Department of Pharmaceutics and Drug Delivery, and his research team are developing technology to use 3D printing technology to streamline vaccine production for flu and other infectious diseases. Photo by Thomas Graning/Ole Miss Digital Imaging Services
Shao 'Kenneth' Feng, a doctoral student in pharmaceutical sciences, cultures bioengineered strains of yeast in Mo Maniruzzaman's lab. These yeasts can produce recombinant protein vaccines on demand and are a key component of Maniruzzaman's research program. Photo by Thomas Graning/Ole Miss Digital Imaging Services
Mo Maniruzzaman (left) works with his research team on setting up a 3D SMART printer to encapsulate vaccine compounds into tiny polymer beads. This technology holds promise to streamline vaccine production. Photo by Thomas Graning/Ole Miss Digital Imaging Services
Pharmacy Assistant
Job posting for pharmacy assistant at partridge chemists.
Job description
- Assist in preparation of prescriptions and delivery of professional services.
Responsibilities
- Assist Pharmacist in providing an efficient, accurate and safe dispensing service in store, ensuring patient confidentiality.
- Assist Pharmacist with other dispensary related tasks e.g. orders, date checks, receiving prescriptions.
- Assist on the medicines counter when required.
- Delivery and collection of prescriptions when required.
- Stock maintenance.
- Retail duties.
- Provide exceptional customer service.
- General Housekeeping.
- Other duties as required.
Skills and Qualifications
Essential Skills
- 5 GCSEs or equivalent including Maths and English.
- Have an interest in Pharmacy and Dispensing.
- Demonstrate exceptional customer service.
- Demonstrate exceptional communication skills.
- Have the ability to work as part of a team.
Further Information
- Equality Statement: Partridge Chemists are an Equal Opportunities Employer. Work time: Monday - Friday 9am-6.00pm, Wednesday and Saturday 9.00am-5.00pm.
- 5 days per week
Job Type: Full-time
Flexible Language Requirement:
- English not required
Work Location: In person
Reference ID: Lgn01
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OXFORD, Miss. - The U.S. Food and Drug Administration has awarded some $500,000 to University of Mississippi pharmacy professor Mo Maniruzzaman, with a recommendation for another $500,000 in 2025, to develop a technology that promises to streamline vaccine production.
Apply for the Job in Pharmacy Assistant at Craigavon, ENG. View the job description, responsibilities and qualifications for this position. Research salary, company info, career paths, and top skills for Pharmacy Assistant