formulation of hypothesis may not be required in

A concise guide to reproducible research using secondary data

Chapter 2 formulating a hypothesis.

“There is no single best way to develop a research idea.” ( Pischke 2012 )

2.1 How do you develop a research question and formulate a hypothesis?

You decide to undertake a scientific project. Where do you start? First, you need to find a research question that interests you and formulate a hypothesis. We will introduce some key terminology, steps you can take, and examples how to develop research questions. Note that .

What if someone assigns a topic to me? For students attending undergraduate and graduate courses that often pick topics from a list, all of these steps are equally important and necessary. You still need to formulate a research question and a hypothesis. And it is important to clarify the relevance of your topic for yourself.

When thinking about a research question, you need to identify a topic that is:

• Relevant , important in the world and interesting to you as a researcher: Does working on the topic excites you? You will spend many hours thinking about it and working on it. Therefore, it should be interesting and engaging enough for you to motivate your continued work on this topic.
• Specific : not too broad and not too narrow
• Feasible to research within a given time frame: Is it possible to answer the research question based on your time budget, data and additional resources.

How do you find a topic or develop a feasible research idea in the first place? Finding an idea is not difficult, the critical part is to find a good idea. How do you do that? There is no one specific way how one gets an idea, rather there is a myriad of ways how people come up with potential ideas (for example, as stated by Varian ( 2016 ) ).

You can find inspiration by

• Looking at insights from the world around you: your own life and experiences, observe the behavior of people around you
• Talking to people around you, experts, other students, family members
• Talking to individuals outside your field (non-economists)
• Talking to professionals working in the area you are interested in (you may use social media and professional platforms like LinkedIN or Twitter to make contact)
• Reading journal articles from other non-economic social sciences and the medical literature
• What are the issues being discussed?
• How do these issues affect people’s lives?

In addition you could

• Go to virtual and in-person seminars, for example, the Essen Health Economics Seminar
• Look at abstracts of scientific articles and working papers
• Look at the literature in a specific field you are interested in, for example, screening complete issues of journals or editorials about certain research advancements. By reading this literature you might come up with the idea on how to extend and refine previous research.

Once you identified a research question that is of interest to you, you need to define a hypothesis.

2.2 What is a hypothesis?

A hypothesis is a statement that introduces your research question and suggests the results you might find. It is an educated guess. You start by posing an economic question and formulate a hypothesis about this question. Then you test it with your data and empirical analysis and either accept or reject the hypothesis. It constitutes the main basis of your scientific investigation and you should be careful when creating it.

2.2.1 Develop a hypothesis

Before you formulate your hypothesis, read up on the topic of interest. This should provide you with sufficient information to narrow down your research question. Once you find your question you need to develop a hypothesis, which contains a statement of your expectations regarding your research question’s results. You propose to prove your hypothesis with your research by testing the relationship between two variables of interest. Thus, a hypothesis should be testable with the data at hand. There are two types of hypotheses: alternative or null. Null states that there is no effect. Alternative states that there is an effect.

There is an alternative view on this that suggests one should not look at the literature too early on in the idea-generating process to not be influenced and shaped by someone else’s ideas ( Varian 2016 ) . According to this view you can spend some time (i.e. a few weeks) trying to develop your own original idea. Even if you end up with an idea that has already been pursued by someone else, this will still provide you with good practice in developing publishable ideas. After you have developed an idea and made sure that it was not yet investigated in the literature, you can start conducting a systematic literature review. By doing this, you can find some other interesting insights from the work of others that you can synthesize in your own work to produce something novel and original.

2.2.2 Identify relevant literature

For your research project you will need to identify and collect previous relevant literature. It should involve a thorough search of the keywords in relevant databases and journals. Place emphasis on articles from high-ranking journals with significant numbers of citations. This will give you an indication of the most influential and important work in the field. Once you identify and collect the relevant literature for your topic, you will need to critically synthesize it in your literature review.

When you perform your literature review, consider theories that may inform your research question. For example, when studying physician behavior you may consider principal-agent theory.

2.2.3 Research question or literature review: the chicken or the egg problem?

Whether you start reading the literature first or by developing an idea may depend on your level (graduate student, early career researcher) and other goals. However, thinking freely about what you like to investigate first may help to critically develop a feasible and interesting research question.

We highlight an example how to start with investigating the real world and subsequently posing a research question ( “How to Write a Strong Hypothesis Steps and Examples ” 2019 ; “Developing Strong Research Questions Criteria and Examples ” 2019 ; Schilbach 2019 ) . For example, based on your observation you notice that people spend extensive amount of time looking at their smartphones. Maybe even you yourself engage in the same behavior. In addition, you read a BBC News article Social media damages teenagers’ mental health, report says .

(#fig:social_media)Social media and mental health

Source: BBC

You decide to translate this article and your observations into a research question : How does social media use affect mental health? Before you formulate your hypothesis, read up on the topic of interest. Read economic, medical and other social science literature on the topic. There is likely to be a vast amount of literature from non-economic fields that are doing research on your topic of interest, for example, psychology or neuroscience. Familiarize yourself with it and master it. Do not get distracted by different scientific methodologies and techniques that might seem not up-to-par to the economic studies (small sample sizes, endogeneity, uncovering association rather than causation, etc.), but rather focus on suggestions of potential mechanisms.

A hypothesis is then your research question distilled into a one sentence statement, which presents your expectations regarding the results. You propose to prove your hypothesis by testing the relationship between two variables of interest with the data at hand. There are two types of hypotheses: alternative or null. The null hypothesis states that there is no effect. The alternative hypothesis states that there is an effect.

A hypothesis related to the above-stated research question could be: The increased use of social media among teenagers leads to (is associated with) worse mental health outcomes, i.e. increased incidence of depression, eating disorders, worse well-being and lower self-esteem. It suggests a direction of a relationship that you expect to find that is guided by your observations and existing evidence. It is testable with scientific research methods by using statistical analysis of the relevant data.

Your hypothesis suggests a relationship between two variables: social media use (your independent variable \(X\) ) and mental health (dependent variable \(Y\) ). It could be framed in terms of correlation (is associated with) or causation (leads to). This should be reflected in the choice of scientific investigation you decide to undertake.

The null hypothesis is: There is no relationship between social media use among teenagers and their mental health .

2.3 Resources box

2.3.1 how to develop strong research questions.

• The form of the research process
• Varian, H. R. (2016). How to build an economic model in your spare time. The American Economist, 61(1), 81-90.

2.3.2 Identify relevant literature from major general interest and field literature

To identify the relevant literature you can

• use academic search engines such as Google Scholar, Web of Science, EconLit, PubMed.
• search working paper series such as the National Bureau of Economic Research , NetEc or IZA
• search more general resource sites such as Resources for Economists
• go to the library/use library database

2.3.3 Assess the quality of a journal article

Several rankings may help to assess the quality of research you consider

• Journals of general interest and by field in economics and management - For German-speaking countries, consider the VWL / BWL Handelsblatt Ranking for economics and management - The German Association of Management Scholars provides an expert-based ranking VHB JourQual 3.0, Teilranking Management im Gesundheitswesen - Web of Science Impact Factors - Scimago
• Health Economics, Health Services and Health Care Managment Research: Health Economics Journals List
• Be aware that like in any other domain there are predatory publishing practices .

Use tools to investigate how a journal article is connected to other works

• Citationgecko
• Connected papers
• scite_ – a tool to get a first impression whether a study is disputed or academic consensus

2.3.4 Organize your literature

• Zotero (free of charge)
• Mendeley (free of charge)
• EndNote (potentially free of charge via your university)
• Citavi (potentially free of charge via your university)
• BibTEX if you work with TEX
• Excel spread sheet

2.4 Checklist to get started with formulating your hypothesis

• Find an interesting and relevant research topic, if not assigned
• Try to suck up all information you can easily obtain from various sources within and outside academic literature
• Formulate one compelling research question
• Find the best available empirical and theoretical evidence that is related to your research question
• Formulate a hypothesis
• Check whether data are available for analysis
• Challenge your idea with your fellows or senior researchers

2.5 Example: Hellerstein ( 1998 )

As an illustration of the research process of formulating a hypothesis, designing a study, running a study, collecting and analyzing the data and, finally, reporting the study, we provide an example by replicating Judith K. Hellerstein’s paper “The Importance of the Physician in the Generic versus Trade-Name Prescription Decision” that was published in 1998 in the RAND Journal of Economics.

Hellerstein’s 1998 paper has impacted discussion about behavioral factors of physician decisions and pharmaceutical markets over two decades. The study received 448 citations on Google Scholar since 1998 by 27/03/2022, including recent mentions in top field journals such as Journal of Public Economics (2021) , Journal of Health Economics (2019) , and Health Economics (2019) .

Figure 2.1: Connected graph of Hellerstein ( 1998 ) , February 2022

Figure 2.1 shows a connected graph of prior and derivative works related to the study.

The work has impacted the literature researching the role of physician behavior and its influence on access, adoption and diffusion of health services, moral hazard and incentives in prescription and treatment decisions and the influence of different payment schemes, and a vast body of literature studying the pharmaceutical market.

The research that has been influenced by Hellerstein includes evidence on:

• generic drug entries and market efficiency
• the effectiveness of pharmaceutical promotion
• the effectiveness of price regulations
• the role of patents and dynamics of market segmentation

At the end of each chapter, we demonstrate insights into this study that we replicate.

2.5.1 Context of the study - escalating health expenditures

In the United States, the total prescription drug expenditure in 2020 marked about 358.7 billion US Dollars ( Statista n.d. ) . The prescription of generic drugs in comparison to more expensive brand-name versions is an option in reducing the total health care expenditure. Generic drugs are bioequivalent in the active ingredients and can serve as a channel to contain prescription expenditure ( Kesselheim 2008 ) as generic drugs are between 20 and 90% cheaper than their trade-name alternatives ( Dunne et al. 2013 ) .

2.5.2 Research question - How does a patient’s insurance status influence the physician’s choice between generic compared to brand-name drugs?

Physicians are faced with a multitude of medication options, including the choice between generic and trade-name drugs. Physicians ideally act as agents for their patients to identify the best available treatment option based on their needs. Choosing the best treatment entails cost of coordination and cognition. The prescription of generic drugs may serve as an example to what extent physicians customize treatments according to patients’ needs with regards to cost. From an economic point of view we may expect that once a generic drug is available, a perfectly rational agent (i.e. physician) would prescribe a generic drug instead of the trade-name version if therapeutically identical ( Dranove 1989 ) . This leads to the following research question: “Do physicians vary their prescription decisions on a patient-by-patient basis or do they systematically prescribe the same version, trade-name or generic, to all patients?” .

The 1998 Hellerstein’s study examines two hypotheses:

• The physician prescribing choice influences the selection of a generic over a brand-name drug
• The patient’s insurance status influences the physician’s choice between generic and brand-name drugs.

For the purpose of this example and in the replication exercise we focus on the second aspect.

2.5.3 Hypothesis

The paper formulates the following hypothesis:

Physicians are more likely to prescribe generics to patients who do not have insurance coverage for prescription pharmaceuticals (moral hazard in insurance)

Hellerstein ( 1998 ) discusses that, based on insurance status, some patients may demand certain care more than others. If, for example, the prescription drug is reimbursed by the patient’s health insurance, this may cause overconsumption. This behavior can potentially differ by the patient’s insurance scheme. A patient that has no insurance and, thus, does not get any reimbursement for prescription drugs, might have a higher incentive to demand cheaper generic drugs ( Danzon and Furukawa 2011 ) than a patient with insurance that covers prescription drugs, either generic or trade-name. Given that the United States have different insurance schemes with varying prescription drug coverage, it is of interest to investigate the role of a patient’s insurance status in the physician’s choice between generic compared to brand-name drugs.

Hellerstein ( 1998 ) considers a patient’s insurance status as a matter of dividing the study population in groups for which the choice between generic and brand-name drugs differs. She suggests that There is a relationship between the prescription of a generic drug and insurance status of a patient. ( Hellerstein 1998 ) .

Providing answers to a research question requires formulating and testing a hypothesis. Based on logic, theory or previous research, a hypothesis proposes an expected relationship within the given data. According to her research question, Hellerstein hypothesizes that: Physicians are more likely to prescribe generics to patients who do not have insurance coverage for prescription pharmaceuticals.

Specifically, she writes “if there is moral hazard in insurance when it comes to physician prescription behavior, there will be differences in the propensity of physicians to prescribe low-cost generic drugs, and these differences will be (partially) a function of the insurance held by the patient. In particular, if moral hazard exists, patients with extensive insurance coverage for prescription drugs (like those on Medicaid in 1989) should receive prescriptions written for generic drugs less frequently than patients with no prescription drug coverage.” ( Hellerstein 1998, 113 )

Based on Hellerstein’s considerations, we expect the effect of the insurance status on whether a patient receives a generic to be different from zero. To obtain a testable null hypothesis, we reformulate this relationship so that we reject the hypothesis if our expectations are correct. This means, if we expect to see an effect of insurance on prescriptions of generics, our null hypothesis is that insurance status has no effect on the outcome (prescription of generic drugs). No moral hazard arises from having obtained insurance.

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scientific hypothesis

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• National Center for Biotechnology Information - PubMed Central - On the scope of scientific hypotheses
• LiveScience - What is a scientific hypothesis?
• The Royal Society - Open Science - On the scope of scientific hypotheses

scientific hypothesis , an idea that proposes a tentative explanation about a phenomenon or a narrow set of phenomena observed in the natural world. The two primary features of a scientific hypothesis are falsifiability and testability, which are reflected in an “If…then” statement summarizing the idea and in the ability to be supported or refuted through observation and experimentation. The notion of the scientific hypothesis as both falsifiable and testable was advanced in the mid-20th century by Austrian-born British philosopher Karl Popper .

The formulation and testing of a hypothesis is part of the scientific method , the approach scientists use when attempting to understand and test ideas about natural phenomena. The generation of a hypothesis frequently is described as a creative process and is based on existing scientific knowledge, intuition , or experience. Therefore, although scientific hypotheses commonly are described as educated guesses, they actually are more informed than a guess. In addition, scientists generally strive to develop simple hypotheses, since these are easier to test relative to hypotheses that involve many different variables and potential outcomes. Such complex hypotheses may be developed as scientific models ( see scientific modeling ).

Depending on the results of scientific evaluation, a hypothesis typically is either rejected as false or accepted as true. However, because a hypothesis inherently is falsifiable, even hypotheses supported by scientific evidence and accepted as true are susceptible to rejection later, when new evidence has become available. In some instances, rather than rejecting a hypothesis because it has been falsified by new evidence, scientists simply adapt the existing idea to accommodate the new information. In this sense a hypothesis is never incorrect but only incomplete.

The investigation of scientific hypotheses is an important component in the development of scientific theory . Hence, hypotheses differ fundamentally from theories; whereas the former is a specific tentative explanation and serves as the main tool by which scientists gather data, the latter is a broad general explanation that incorporates data from many different scientific investigations undertaken to explore hypotheses.

Countless hypotheses have been developed and tested throughout the history of science . Several examples include the idea that living organisms develop from nonliving matter, which formed the basis of spontaneous generation , a hypothesis that ultimately was disproved (first in 1668, with the experiments of Italian physician Francesco Redi , and later in 1859, with the experiments of French chemist and microbiologist Louis Pasteur ); the concept proposed in the late 19th century that microorganisms cause certain diseases (now known as germ theory ); and the notion that oceanic crust forms along submarine mountain zones and spreads laterally away from them ( seafloor spreading hypothesis ).

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• v.36(50); 2021 Dec 27

Formulating Hypotheses for Different Study Designs

Durga prasanna misra.

1 Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.

Armen Yuri Gasparyan

2 Departments of Rheumatology and Research and Development, Dudley Group NHS Foundation Trust (Teaching Trust of the University of Birmingham, UK), Russells Hall Hospital, Dudley, UK.

Olena Zimba

3 Department of Internal Medicine #2, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine.

Marlen Yessirkepov

4 Department of Biology and Biochemistry, South Kazakhstan Medical Academy, Shymkent, Kazakhstan.

Vikas Agarwal

George d. kitas.

5 Centre for Epidemiology versus Arthritis, University of Manchester, Manchester, UK.

Generating a testable working hypothesis is the first step towards conducting original research. Such research may prove or disprove the proposed hypothesis. Case reports, case series, online surveys and other observational studies, clinical trials, and narrative reviews help to generate hypotheses. Observational and interventional studies help to test hypotheses. A good hypothesis is usually based on previous evidence-based reports. Hypotheses without evidence-based justification and a priori ideas are not received favourably by the scientific community. Original research to test a hypothesis should be carefully planned to ensure appropriate methodology and adequate statistical power. While hypotheses can challenge conventional thinking and may be controversial, they should not be destructive. A hypothesis should be tested by ethically sound experiments with meaningful ethical and clinical implications. The coronavirus disease 2019 pandemic has brought into sharp focus numerous hypotheses, some of which were proven (e.g. effectiveness of corticosteroids in those with hypoxia) while others were disproven (e.g. ineffectiveness of hydroxychloroquine and ivermectin).

Graphical Abstract

DEFINING WORKING AND STANDALONE SCIENTIFIC HYPOTHESES

Science is the systematized description of natural truths and facts. Routine observations of existing life phenomena lead to the creative thinking and generation of ideas about mechanisms of such phenomena and related human interventions. Such ideas presented in a structured format can be viewed as hypotheses. After generating a hypothesis, it is necessary to test it to prove its validity. Thus, hypothesis can be defined as a proposed mechanism of a naturally occurring event or a proposed outcome of an intervention. 1 , 2

Hypothesis testing requires choosing the most appropriate methodology and adequately powering statistically the study to be able to “prove” or “disprove” it within predetermined and widely accepted levels of certainty. This entails sample size calculation that often takes into account previously published observations and pilot studies. 2 , 3 In the era of digitization, hypothesis generation and testing may benefit from the availability of numerous platforms for data dissemination, social networking, and expert validation. Related expert evaluations may reveal strengths and limitations of proposed ideas at early stages of post-publication promotion, preventing the implementation of unsupported controversial points. 4

Thus, hypothesis generation is an important initial step in the research workflow, reflecting accumulating evidence and experts' stance. In this article, we overview the genesis and importance of scientific hypotheses and their relevance in the era of the coronavirus disease 2019 (COVID-19) pandemic.

DO WE NEED HYPOTHESES FOR ALL STUDY DESIGNS?

Broadly, research can be categorized as primary or secondary. In the context of medicine, primary research may include real-life observations of disease presentations and outcomes. Single case descriptions, which often lead to new ideas and hypotheses, serve as important starting points or justifications for case series and cohort studies. The importance of case descriptions is particularly evident in the context of the COVID-19 pandemic when unique, educational case reports have heralded a new era in clinical medicine. 5

Case series serve similar purpose to single case reports, but are based on a slightly larger quantum of information. Observational studies, including online surveys, describe the existing phenomena at a larger scale, often involving various control groups. Observational studies include variable-scale epidemiological investigations at different time points. Interventional studies detail the results of therapeutic interventions.

Secondary research is based on already published literature and does not directly involve human or animal subjects. Review articles are generated by secondary research. These could be systematic reviews which follow methods akin to primary research but with the unit of study being published papers rather than humans or animals. Systematic reviews have a rigid structure with a mandatory search strategy encompassing multiple databases, systematic screening of search results against pre-defined inclusion and exclusion criteria, critical appraisal of study quality and an optional component of collating results across studies quantitatively to derive summary estimates (meta-analysis). 6 Narrative reviews, on the other hand, have a more flexible structure. Systematic literature searches to minimise bias in selection of articles are highly recommended but not mandatory. 7 Narrative reviews are influenced by the authors' viewpoint who may preferentially analyse selected sets of articles. 8

In relation to primary research, case studies and case series are generally not driven by a working hypothesis. Rather, they serve as a basis to generate a hypothesis. Observational or interventional studies should have a hypothesis for choosing research design and sample size. The results of observational and interventional studies further lead to the generation of new hypotheses, testing of which forms the basis of future studies. Review articles, on the other hand, may not be hypothesis-driven, but form fertile ground to generate future hypotheses for evaluation. Fig. 1 summarizes which type of studies are hypothesis-driven and which lead on to hypothesis generation.

STANDARDS OF WORKING AND SCIENTIFIC HYPOTHESES

A review of the published literature did not enable the identification of clearly defined standards for working and scientific hypotheses. It is essential to distinguish influential versus not influential hypotheses, evidence-based hypotheses versus a priori statements and ideas, ethical versus unethical, or potentially harmful ideas. The following points are proposed for consideration while generating working and scientific hypotheses. 1 , 2 Table 1 summarizes these points.

Evidence-based data

A scientific hypothesis should have a sound basis on previously published literature as well as the scientist's observations. Randomly generated (a priori) hypotheses are unlikely to be proven. A thorough literature search should form the basis of a hypothesis based on published evidence. 7

Unless a scientific hypothesis can be tested, it can neither be proven nor be disproven. Therefore, a scientific hypothesis should be amenable to testing with the available technologies and the present understanding of science.

Supported by pilot studies

If a hypothesis is based purely on a novel observation by the scientist in question, it should be grounded on some preliminary studies to support it. For example, if a drug that targets a specific cell population is hypothesized to be useful in a particular disease setting, then there must be some preliminary evidence that the specific cell population plays a role in driving that disease process.

Testable by ethical studies

The hypothesis should be testable by experiments that are ethically acceptable. 9 For example, a hypothesis that parachutes reduce mortality from falls from an airplane cannot be tested using a randomized controlled trial. 10 This is because it is obvious that all those jumping from a flying plane without a parachute would likely die. Similarly, the hypothesis that smoking tobacco causes lung cancer cannot be tested by a clinical trial that makes people take up smoking (since there is considerable evidence for the health hazards associated with smoking). Instead, long-term observational studies comparing outcomes in those who smoke and those who do not, as was performed in the landmark epidemiological case control study by Doll and Hill, 11 are more ethical and practical.

Balance between scientific temper and controversy

Novel findings, including novel hypotheses, particularly those that challenge established norms, are bound to face resistance for their wider acceptance. Such resistance is inevitable until the time such findings are proven with appropriate scientific rigor. However, hypotheses that generate controversy are generally unwelcome. For example, at the time the pandemic of human immunodeficiency virus (HIV) and AIDS was taking foot, there were numerous deniers that refused to believe that HIV caused AIDS. 12 , 13 Similarly, at a time when climate change is causing catastrophic changes to weather patterns worldwide, denial that climate change is occurring and consequent attempts to block climate change are certainly unwelcome. 14 The denialism and misinformation during the COVID-19 pandemic, including unfortunate examples of vaccine hesitancy, are more recent examples of controversial hypotheses not backed by science. 15 , 16 An example of a controversial hypothesis that was a revolutionary scientific breakthrough was the hypothesis put forth by Warren and Marshall that Helicobacter pylori causes peptic ulcers. Initially, the hypothesis that a microorganism could cause gastritis and gastric ulcers faced immense resistance. When the scientists that proposed the hypothesis themselves ingested H. pylori to induce gastritis in themselves, only then could they convince the wider world about their hypothesis. Such was the impact of the hypothesis was that Barry Marshall and Robin Warren were awarded the Nobel Prize in Physiology or Medicine in 2005 for this discovery. 17 , 18

DISTINGUISHING THE MOST INFLUENTIAL HYPOTHESES

Influential hypotheses are those that have stood the test of time. An archetype of an influential hypothesis is that proposed by Edward Jenner in the eighteenth century that cowpox infection protects against smallpox. While this observation had been reported for nearly a century before this time, it had not been suitably tested and publicised until Jenner conducted his experiments on a young boy by demonstrating protection against smallpox after inoculation with cowpox. 19 These experiments were the basis for widespread smallpox immunization strategies worldwide in the 20th century which resulted in the elimination of smallpox as a human disease today. 20

Other influential hypotheses are those which have been read and cited widely. An example of this is the hygiene hypothesis proposing an inverse relationship between infections in early life and allergies or autoimmunity in adulthood. An analysis reported that this hypothesis had been cited more than 3,000 times on Scopus. 1

LESSONS LEARNED FROM HYPOTHESES AMIDST THE COVID-19 PANDEMIC

The COVID-19 pandemic devastated the world like no other in recent memory. During this period, various hypotheses emerged, understandably so considering the public health emergency situation with innumerable deaths and suffering for humanity. Within weeks of the first reports of COVID-19, aberrant immune system activation was identified as a key driver of organ dysfunction and mortality in this disease. 21 Consequently, numerous drugs that suppress the immune system or abrogate the activation of the immune system were hypothesized to have a role in COVID-19. 22 One of the earliest drugs hypothesized to have a benefit was hydroxychloroquine. Hydroxychloroquine was proposed to interfere with Toll-like receptor activation and consequently ameliorate the aberrant immune system activation leading to pathology in COVID-19. 22 The drug was also hypothesized to have a prophylactic role in preventing infection or disease severity in COVID-19. It was also touted as a wonder drug for the disease by many prominent international figures. However, later studies which were well-designed randomized controlled trials failed to demonstrate any benefit of hydroxychloroquine in COVID-19. 23 , 24 , 25 , 26 Subsequently, azithromycin 27 , 28 and ivermectin 29 were hypothesized as potential therapies for COVID-19, but were not supported by evidence from randomized controlled trials. The role of vitamin D in preventing disease severity was also proposed, but has not been proven definitively until now. 30 , 31 On the other hand, randomized controlled trials identified the evidence supporting dexamethasone 32 and interleukin-6 pathway blockade with tocilizumab as effective therapies for COVID-19 in specific situations such as at the onset of hypoxia. 33 , 34 Clues towards the apparent effectiveness of various drugs against severe acute respiratory syndrome coronavirus 2 in vitro but their ineffectiveness in vivo have recently been identified. Many of these drugs are weak, lipophilic bases and some others induce phospholipidosis which results in apparent in vitro effectiveness due to non-specific off-target effects that are not replicated inside living systems. 35 , 36

Another hypothesis proposed was the association of the routine policy of vaccination with Bacillus Calmette-Guerin (BCG) with lower deaths due to COVID-19. This hypothesis emerged in the middle of 2020 when COVID-19 was still taking foot in many parts of the world. 37 , 38 Subsequently, many countries which had lower deaths at that time point went on to have higher numbers of mortality, comparable to other areas of the world. Furthermore, the hypothesis that BCG vaccination reduced COVID-19 mortality was a classic example of ecological fallacy. Associations between population level events (ecological studies; in this case, BCG vaccination and COVID-19 mortality) cannot be directly extrapolated to the individual level. Furthermore, such associations cannot per se be attributed as causal in nature, and can only serve to generate hypotheses that need to be tested at the individual level. 39

IS TRADITIONAL PEER REVIEW EFFICIENT FOR EVALUATION OF WORKING AND SCIENTIFIC HYPOTHESES?

Traditionally, publication after peer review has been considered the gold standard before any new idea finds acceptability amongst the scientific community. Getting a work (including a working or scientific hypothesis) reviewed by experts in the field before experiments are conducted to prove or disprove it helps to refine the idea further as well as improve the experiments planned to test the hypothesis. 40 A route towards this has been the emergence of journals dedicated to publishing hypotheses such as the Central Asian Journal of Medical Hypotheses and Ethics. 41 Another means of publishing hypotheses is through registered research protocols detailing the background, hypothesis, and methodology of a particular study. If such protocols are published after peer review, then the journal commits to publishing the completed study irrespective of whether the study hypothesis is proven or disproven. 42 In the post-pandemic world, online research methods such as online surveys powered via social media channels such as Twitter and Instagram might serve as critical tools to generate as well as to preliminarily test the appropriateness of hypotheses for further evaluation. 43 , 44

Some radical hypotheses might be difficult to publish after traditional peer review. These hypotheses might only be acceptable by the scientific community after they are tested in research studies. Preprints might be a way to disseminate such controversial and ground-breaking hypotheses. 45 However, scientists might prefer to keep their hypotheses confidential for the fear of plagiarism of ideas, avoiding online posting and publishing until they have tested the hypotheses.

SUGGESTIONS ON GENERATING AND PUBLISHING HYPOTHESES

Publication of hypotheses is important, however, a balance is required between scientific temper and controversy. Journal editors and reviewers might keep in mind these specific points, summarized in Table 2 and detailed hereafter, while judging the merit of hypotheses for publication. Keeping in mind the ethical principle of primum non nocere, a hypothesis should be published only if it is testable in a manner that is ethically appropriate. 46 Such hypotheses should be grounded in reality and lend themselves to further testing to either prove or disprove them. It must be considered that subsequent experiments to prove or disprove a hypothesis have an equal chance of failing or succeeding, akin to tossing a coin. A pre-conceived belief that a hypothesis is unlikely to be proven correct should not form the basis of rejection of such a hypothesis for publication. In this context, hypotheses generated after a thorough literature search to identify knowledge gaps or based on concrete clinical observations on a considerable number of patients (as opposed to random observations on a few patients) are more likely to be acceptable for publication by peer-reviewed journals. Also, hypotheses should be considered for publication or rejection based on their implications for science at large rather than whether the subsequent experiments to test them end up with results in favour of or against the original hypothesis.

Hypotheses form an important part of the scientific literature. The COVID-19 pandemic has reiterated the importance and relevance of hypotheses for dealing with public health emergencies and highlighted the need for evidence-based and ethical hypotheses. A good hypothesis is testable in a relevant study design, backed by preliminary evidence, and has positive ethical and clinical implications. General medical journals might consider publishing hypotheses as a specific article type to enable more rapid advancement of science.

Disclosure: The authors have no potential conflicts of interest to disclose.

Author Contributions:

• Data curation: Gasparyan AY, Misra DP, Zimba O, Yessirkepov M, Agarwal V, Kitas GD.

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• Formulation of Hypothesis

Children who spend more time playing outside are more likely to be imaginative. What do you think this statement is an example of in terms of scientific research ? If you guessed a hypothesis, then you'd be correct. The formulation of hypotheses is a fundamental step in psychology research.

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What is a hypothesis? 

What method states that a hypothesis needs to be formulated to produce good research?

What type of hypothesis matches the following definition. A hypothesis that states that the IV will influence the DV, and states how it will influence the DV. 

Which type of hypothesis is also known as a two-tailed hypothesis? 

What are the requirements of a good hypothesis? 

What steps do researchers need to take when formulating a testable hypothesis? 

What is a hypothesis predicting? 

What type of hypothesis matches the following definition. A predictive statement that researchers use when it is thought that the IV will not influence the DV.

What type of hypothesis is the following example. There will be no observed difference in scores from a memory performance task between people with high- or low-depressive scores.

Why are hypotheses needed in research? 

What is an operationalised variable?

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• Approaches in Psychology
• Basic Psychology
• Biological Bases of Behavior
• Biopsychology
• Careers in Psychology
• Clinical Psychology
• Bartlett War of the Ghosts
• Brain Development
• Bruner and Minturn Study of Perceptual Set
• Case Studies Psychology
• Computation
• Conservation of Number Piaget
• Constructive Processes in Memory
• Correlation
• Data handling
• Depth Cues Psychology
• Designing Research
• Developmental Research
• Dweck's Theory of Mindset
• Ethical considerations in research
• Experimental Method
• Factors Affecting Perception
• Factors Affecting the Accuracy of Memory
• Gibson's Theory of Direct Perception
• Gregory's Constructivist Theory of Perception
• Gunderson et al 2013 study
• Hughes Policeman Doll Study
• Issues and Debates in Developmental Psychology
• Language and Perception
• McGarrigle and Donaldson Naughty Teddy
• Memory Processes
• Memory recall
• Nature and Nurture in Development
• Normal Distribution Psychology
• Perception Research
• Perceptual Set
• Piagets Theory in Education
• Planning and Conducting Research
• Population Samples
• Primary and Secondary Data
• Quantitative Data
• Quantitative and Qualitative Data
• Quantitative and Qualitative Methods
• Research Procedures
• Serial Position Effect
• Short-term Retention
• Structures of Memory
• Tables, Charts and Graphs
• The Effects of Learning on Development
• The Gilchrist And Nesberg Study Of Motivation
• Three Mountains Task
• Types of Variable
• Types of bias and how to control
• Visual Cues and Constancies
• Visual illusions
• Willingham's Learning Theory
• Cognition and Development
• Cognitive Psychology
• Data Handling and Analysis
• Developmental Psychology
• Eating Behaviour
• Emotion and Motivation
• Famous Psychologists
• Forensic Psychology
• Health Psychology
• Individual Differences Psychology
• Issues and Debates in Psychology
• Personality in Psychology
• Psychological Treatment
• Relationships
• Research Methods in Psychology
• Schizophrenia
• Scientific Foundations of Psychology
• Scientific Investigation
• Sensation and Perception
• Social Context of Behaviour
• Social Psychology
• First, we will discuss the importance of hypotheses in research.
• We will then cover formulating hypotheses in research, including the steps in the formulation of hypotheses in research methodology.
• We will provide examples of hypotheses in research throughout the explanation.
• Finally, we will delve into the different types of hypotheses in research.

What is a Hypothesis?

The current community of psychologists believe that the best approach to understanding behaviour is to conduct scientific research . To be classed as scientific research , it must be observable, valid, reliable and follow a standardised procedure.

One of the important steps in scientific research is to formulate a hypothesis before starting the study procedure.

The hypothesis is a predictive, testable statement predicting the outcome and the results the researcher expects to find.

The hypothesis provides a summary of what direction, if any, is taken to investigate a theory.

In scientific research, there is a criterion that hypotheses need to be met to be regarded as acceptable.

If a hypothesis is disregarded, the research may be rejected by the community of psychology researchers.

Importance of Hypothesis in Research

The purpose of including hypotheses in psychology research is:

• To provide a summary of the research, how it will be investigated, and what is expected to be found.
• To provide an answer to the research question.

When carrying out research, researchers first investigate the research area they are interested in. From this, researchers are required to identify a gap in the literature.

Filling the gap essentially means finding what previous work has not been explained yet, investigated to a sufficient degree, or simply expanding or further investigating a theory if doubt exists.

The researcher then forms a research question that the researcher will attempt to answer in their study.

Remember, the hypothesis is a predictive statement of what is expected to happen when testing the research question.

The hypothesis can be used for later data analysis. This includes inferential tests such as hypothesis testing and identifying if statistical findings are significant.

Steps in the Formulation of Hypothesis in Research Methodology

Researchers must follow certain steps to formulate testable hypotheses when conducting research.

Overall, the researcher has to consider the direction of the research, i.e. will it be looking for a difference caused by independent variables ? Or will it be more concerned with the correlation between variables?

All researchers will likely complete the following.

• Investigating background research in the area of interest.
• Formulating or investigating a theory.
• Identify how the theory will be tested and what the researcher expects to find based on relevant, previously published scientific works.

The above steps are used to formulate testable hypotheses.

The Formulation of Testable Hypotheses

The hypothesis is important in research as it indicates what and how a variable will be investigated.

The hypothesis essentially summarises what and how something will be investigated. This is important as it ensures that the researcher has carefully planned how the research will be done, as the researchers have to follow a set procedure to conduct research.

This is known as the scientific method.

Formulating Hypotheses in Research

When formulating hypotheses, things that researchers should consider are:

Types of Hypotheses in Research

Researchers can propose different types of hypotheses when carrying out research.

The following research scenario will be discussed to show examples of each type of hypothesis that the researchers could use. "A research team was investigating whether memory performance is affected by depression ."

The identified independent variable is the severity of depression scores, and the dependent variable is the scores from a memory performance task.

The null hypothesis predicts that the results will show no or little effect. The null hypothesis is a predictive statement that researchers use when it is thought that the IV will not influence the DV.

In this case, the null hypothesis would be there will be no difference in memory scores on the MMSE test of those who are diagnosed with depression and those who are not.

An alternative hypothesis is a predictive statement used when it is thought that the IV will influence the DV. The alternative hypothesis is also called a non-directional, two-tailed hypothesis, as it predicts the results can go either way, e.g. increase or decrease.

The example in this scenario is there will be an observed difference in scores from a memory performance task between people with high- or low-depressive scores.

The directional alternative hypothesis states how the IV will influence the DV, identifying a specific direction, such as if there will be an increase or decrease in the observed results.

The example in this scenario is people with low depressive scores will perform better in the memory performance task than people who score higher in depressive symptoms.

Example Hypothesis in Research

To summarise, let's look at an example of a straightforward hypothesis that indicates the relationship between two variables: the independent and the dependent.

If you stay up late, you will feel tired the following day; the more caffeine you drink, the harder you find it to fall asleep, or the more sunlight plants get, the taller they will grow.

Formulation of Hypothesis - Key Takeaways

• The current community of psychologists believe that the best approach to understanding behaviour is to conduct scientific research. One of the important steps in scientific research is to create a hypothesis.
• The hypothesis is a predictive, testable statement concerning the outcome/results that the researcher expects to find.
• Hypotheses are needed in research to provide a summary of what the research is, how to investigate a theory and what is expected to be found, and to provide an answer to the research question so that the hypothesis can be used for later data analysis.
• There are requirements for the formulation of testable hypotheses. The hypotheses should identify and operationalise the IV and DV. In addition, they should describe the nature of the relationship between the IV and DV.
• There are different types of hypotheses: Null hypothesis, Alternative hypothesis (this is also known as the non-directional, two-tailed hypothesis), and Directional hypothesis (this is also known as the one-tailed hypothesis).

Flashcards in Formulation of Hypothesis 18

The hypothesis is a predictive, testable statement concerning the outcome/ results the researcher expects to find. 

The scientific method states that researchers need to formulate a good hypothesis before starting the research. 

Directional, alternative hypothesis 

Alternative hypothesis 

A good hypothesis should:

• identify and operationalise the independent and dependent variable
• be testable 
• be falsifiable 
• predictive statements 

All researchers will likely complete the following

• Investigating background research in the area of interest 
• Formulating or investigating a theory 
• Identify how the theory will be tested and what the researcher expects to find based on relevant, previously published scientific works 

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Frequently Asked Questions about Formulation of Hypothesis

What are the 3 types of hypotheses?

The three types of hypotheses are:

• Null hypothesis 
• Alternative hypothesis 
• Directional/non-directional hypothesis 

What is an example of a hypothesis in psychology?

An example of a null hypothesis in psychology is, there will be no observed difference in scores from a memory performance task between people with high- or low-depressive scores.

What are the steps in formulating a hypothesis?

• Investigating background research in the area of interest 
• Formulating or investigating a theory 
• Identify how the theory will be tested and what the researcher expects to find based on relevant, previously published scientific works 

What is formulation of hypothesis in research? 

The formulation of a hypothesis in research is when the researcher formulates a predictive statement of what is expected to happen when testing the research question based on background research.

How to formulate  null and alternative hypothesis?

When formulating a null hypothesis the researcher would state a prediction that they expect to see no difference in the dependent variable when the independent variable changes or is manipulated. Whereas, when using an alternative hypothesis then it would be predicted that there will be a change in the dependent variable. The researcher can state in which direction they expect the results to go. 

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Definition of a Hypothesis

What it is and how it's used in sociology

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A hypothesis is a prediction of what will be found at the outcome of a research project and is typically focused on the relationship between two different variables studied in the research. It is usually based on both theoretical expectations about how things work and already existing scientific evidence.

Within social science, a hypothesis can take two forms. It can predict that there is no relationship between two variables, in which case it is a null hypothesis . Or, it can predict the existence of a relationship between variables, which is known as an alternative hypothesis.

In either case, the variable that is thought to either affect or not affect the outcome is known as the independent variable, and the variable that is thought to either be affected or not is the dependent variable.

Researchers seek to determine whether or not their hypothesis, or hypotheses if they have more than one, will prove true. Sometimes they do, and sometimes they do not. Either way, the research is considered successful if one can conclude whether or not a hypothesis is true. 

Null Hypothesis

A researcher has a null hypothesis when she or he believes, based on theory and existing scientific evidence, that there will not be a relationship between two variables. For example, when examining what factors influence a person's highest level of education within the U.S., a researcher might expect that place of birth, number of siblings, and religion would not have an impact on the level of education. This would mean the researcher has stated three null hypotheses.

Alternative Hypothesis

Taking the same example, a researcher might expect that the economic class and educational attainment of one's parents, and the race of the person in question are likely to have an effect on one's educational attainment. Existing evidence and social theories that recognize the connections between wealth and cultural resources , and how race affects access to rights and resources in the U.S. , would suggest that both economic class and educational attainment of the one's parents would have a positive effect on educational attainment. In this case, economic class and educational attainment of one's parents are independent variables, and one's educational attainment is the dependent variable—it is hypothesized to be dependent on the other two.

Conversely, an informed researcher would expect that being a race other than white in the U.S. is likely to have a negative impact on a person's educational attainment. This would be characterized as a negative relationship, wherein being a person of color has a negative effect on one's educational attainment. In reality, this hypothesis proves true, with the exception of Asian Americans , who go to college at a higher rate than whites do. However, Blacks and Hispanics and Latinos are far less likely than whites and Asian Americans to go to college.

Formulating a Hypothesis

Formulating a hypothesis can take place at the very beginning of a research project , or after a bit of research has already been done. Sometimes a researcher knows right from the start which variables she is interested in studying, and she may already have a hunch about their relationships. Other times, a researcher may have an interest in ​a particular topic, trend, or phenomenon, but he may not know enough about it to identify variables or formulate a hypothesis.

Whenever a hypothesis is formulated, the most important thing is to be precise about what one's variables are, what the nature of the relationship between them might be, and how one can go about conducting a study of them.

Updated by Nicki Lisa Cole, Ph.D

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5 Basic Steps in Formulation of Hypothesis in Research

Formulation of a Hypothesis in research is an essential task in the entire Research Process that comes in the third step. A hypothesis is a tentative solution to a research problem or question. Here, we will cover a functional definition of a hypothesis & basic Steps in the formulation of hypotheses for your research.

Research works, in fact, are designed to verify the hypothesis. Therefore, a researcher, of course, would understand the meaning and nature of the hypothesis in order to formulate a hypothesis and then test the hypothesis.

What is Hypothesis in Research?

A hypothesis is a tentative statement of a proposition that the researcher seeks to prove. It’s basically a concrete generalization. Of course, this generalization requires essential characteristics that pertain to an entire class of phenomena.

When a theory is stated as a testable proposition formally and subjects to empirical verification we can define it as a hypothesis. Researchers make a hypothesis on the basis of some earlier theories and some rationale that is generally accepted as true. The hypothesis test finally will decide whether it is true or rejected.

So, to clarify a hypothesis is a statement about the relationship between two or more variables. The researcher set out the variables to prove or disprove. Hypothesis essentially includes three elements. For example-

• Relationship between variables.

Example of Hypothesis

• Rewards increase reading achievements
• Rewards decrease reading achievements
• Or rewards have no effect on reading achievements

In the above examples- variables are- Rewards & Achievements.

Steps in Formulation of Hypothesis

A hypothesis is a tentative assumption drawn from practical knowledge or theory. A hypothesis is used as a guide in the inquiry of other facts or theories that a researcher does not know. However, the formulation of the hypothesis is one of the most difficult steps in the entire scientific research process.

Therefore, in this regard, we intend to point out the basic steps in the formulation of a hypothesis. We are pretty sure that this guideline will be helpful in your research work.

1. Define Variables

At first, with a view to formulating a hypothesis, you must define your variables. What do you want to test? Will you test that rewards increase reading achievement? Or do rewards decrease reading achievement? Whatever your goals are, they need to be clearly defined, quantifiable, and measurable. This will provide you with a clear idea of what to follow to achieve results.

2. Study In-Depth the Variables

If we do think that your variables are Rewards & Achievements, then you need to intense study how rewards increase reading achievements? An in-depth study, rigorous questions, and data of rewards increase reading achievements will make you able to confirm your hypothesis. Specify dependent and independent variables.

3. Specify the Nature of the Relationship

Then, identify what relationship there exist between the variables. What variable influences the other? That is what is the dependent variable and what is the independent variable? How do Rewards impact achievements? If reward plays a key role in reading achievements, then reward is the independent variable.

4. Identify Study Population

The population in research means the entire group of individuals is going to study. If you want to test how rewards increase reading achievements in the United Kingdom, you need not study the whole population of the United Kingdom. Because the total population does not involve in reading achievements. Therefore, the researcher must identify the study population.

5. Make Sure Variables are Testable

Variables in your hypothesis must be testable. Otherwise, the hypothesis would be worthless. Because your research study must accept or reject a variable. So, variables you must need to test. Testable variables can only be accepted or rejected. Moreover, the sole aim of a research hypothesis is to test variables in the long run.

How to Choose a Research Design?

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Formulating a hypothesis.

1. Variables

Once you've decided on your research questions and completed your background reading, you will select variables to study and a hypothesis to test. This is where you begin to put your problem solving skills into action.

A variable is a characteristic that varies throughout the population as a whole and which can be used to study differences between people and groups. Population variables can include age, class, income level, level of education, race, veteran status, gender, employment status, whether one drives, whether one smokes, country of origin, language, citizen status, region of the country, city or country dweller, or marital status. These variables are different for each individual, but you can batch together large groups of people who all share a certain variable or set of variables. You can also see how variables impact each other by identifying them and sorting the data.

Focusing on particular variables allows you to isolate those characteristics in order to analyze the influence of these characteristics on the population's experience.

IN CONTEXT If you are studying the effects of wealth transfer through generations, you might look at the relationship between your subjects' income and education levels and their parents' education levels. You might also want to know if all levels of parental education and income have the same effect. What might you hypothesize about the relationship between the two? You might hypothesize that if a subject's father was educated, the subject will be as educated or higher. You might also hypothesize that if a subject's father was educated, the subject will be likelier to earn a higher income. But there are other variables at play here too: age, gender, race, location, the presence of other similarly educated family members, and many others. In formulating your hypothesis, you make a statement about how the variable “father's education” is related to the variable “subject’s education level.” Keep in mind that not all variables are created equal. Some are very critical in explaining a subject's education level, and some aren’t, meaning that they don't strongly relate to the outcome that you’re trying to explain.

There are two different kinds of variables:

An independent variable is the factor that causes the change, or the outcome. You can think of it as the cause. In the example above, the independent variable is the subject's father's education level. It is what drives the change. The dependent variable is the effect or the variable that is influenced by the other. In the example, the dependent variable is the subject's education and income level. You are hypothesizing that the father's education level affects their child's education and income level.

terms to know Variable A characteristic such as age, education, income, or marriage status that can vary throughout the population. Independent Variable The cause of the change, or what drives the change in the dependent variable. Dependent Variable The effect of the change; a variable changed by other variables.

2. Formulating a Hypothesis

People commonly try to understand the happenings in their world by finding or creating an explanation for an occurrence, which is what we referred to earlier as common sense. Social scientists may develop a hypothesis for the same reason.

A hypothesis is a testable, informed guess about predicted outcomes between two or more variables; it’s a possible explanation for specific happenings in the social world and allows for testing to determine whether the explanation holds true in many instances, as well as among various groups or in different places. The hypothesis will often predict how one form of human behavior influences another. The independent variable is the cause of the change, or the variable that influences the other variable. The dependent variable is the effect, or variable that is changed. It depends on the independent variable.

big idea The hypothesis is the researcher's guess—based on background research—about the answer to the research question. A hypothesis often concerns how one thing affects another, which is another way of saying how the independent variable impacts the dependent variable.

In putting together their hypotheses, researchers establish one form of human behavior as the independent variable and observe the influence it has on a dependent variable.

hint It is important to note that at this stage we are suggesting relationships between variables, or correlation. We are not yet suggesting that one variable is the cause of another, just that one variable changes when another variable changes in a predictable way.

As the table shows, an independent variable is the one that influences the other variable. Rather than being “right,” sociologists are interested in the relationships between variables. If we were to examine the last example, what other variables might come into play? Would we see similar patterns of income for all college-educated people or are there disparities for racial and ethnic minorities? Gender minorities? First, we must move into the next research steps: designing and conducting a study and drawing conclusions. You’ll learn more about these types of research methods in the next section of the course.

term to know Hypothesis A testable, informed guess about predicted outcomes between two or more variables.

3. Sampling

What happens after you gravitate towards a topic, come up with a hypothesis, and hypothesize a relationship between an independent variable and a dependent variable? Most likely it won't be practical to plan on studying an entire population of a city or country. You need to use a sample of the population as a whole.

A sample is a smaller group of subjects that ideally represents the population as a whole. You use a sample because it is impossible to go and ask everyone in the whole population, so you have to take a slice of the whole population. The goal, then, is to have a representative sample where all facets of interest of the study are included. The only requirement is that the sample be random.

hint When selecting a sample of a population for a study, the goal is to select a sample that is representative of the entire population.

One effective way to get a sample is through a technique called snowball sampling . In snowball sampling, you find your initial respondents or subjects through acquaintances that you already have in your network. You then use those acquaintances to find their acquaintances, and so on, and the process snowballs.

terms to know Sample A smaller group of subjects that ideally represents the larger population as a whole. Snowball Sampling A sampling technique where initial subjects are found through acquaintances, and later subjects are found through acquaintances of acquaintances.

summary In this lesson, you learned about how sociologists go about formulating a hypothesis , including establishing independent and dependent variables . You saw why sampling is a useful approach to making a huge population something small enough to work with but still representative. You also strengthened your problem solving skill by beginning to consider educated solutions to problems in society. Best of luck in your learning!

Source: THIS TUTORIAL HAS BEEN ADAPTED FROM "INTRODUCTION TO SOCIOLOGY" BY LUMEN LEARNING. ACCESS FOR FREE AT LUMEN LEARNING . LICENSE: CREATIVE COMMONS ATTRIBUTION 4.0 INTERNATIONAL.

The effect of the change. a variable changed by other variables.

A testable educated guess about predicted outcomes between two or more variables.

The cause of the change, or what drives the change in the dependent variable.

A smaller group of subjects that ideally represents the larger population as a whole.

A sampling technique where initial subjects are found through acquaintances, and later subjects are found through acquaintances of acquaintances.

A characteristic such as age, education, income, or marriage status that can vary throughout the population.

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• Formulation of Hypothesis

Children who spend more time playing outside are more likely to be imaginative. What do you think this statement is an example of in terms of scientific research ? If you guessed a hypothesis, then you'd be correct. The formulation of hypotheses is a fundamental step in psychology research.

Create learning materials about Formulation of Hypothesis with our free learning app!

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• Cell Biology

What is a hypothesis? 

What method states that a hypothesis needs to be formulated to produce good research?

What type of hypothesis matches the following definition. A hypothesis that states that the IV will influence the DV, and states how it will influence the DV. 

Which type of hypothesis is also known as a two-tailed hypothesis? 

What are the requirements of a good hypothesis? 

What steps do researchers need to take when formulating a testable hypothesis? 

What is a hypothesis predicting? 

What type of hypothesis matches the following definition. A predictive statement that researchers use when it is thought that the IV will not influence the DV.

What type of hypothesis is the following example. There will be no observed difference in scores from a memory performance task between people with high- or low-depressive scores.

Why are hypotheses needed in research? 

What is an operationalised variable?

Convert documents into flashcards for free with AI!

• Approaches in Psychology
• Basic Psychology
• Biological Bases of Behavior
• Biopsychology
• Careers in Psychology
• Clinical Psychology
• Bartlett War of the Ghosts
• Brain Development
• Bruner and Minturn Study of Perceptual Set
• Case Studies Psychology
• Computation
• Conservation of Number Piaget
• Constructive Processes in Memory
• Correlation
• Data handling
• Depth Cues Psychology
• Designing Research
• Developmental Research
• Dweck's Theory of Mindset
• Ethical considerations in research
• Experimental Method
• Factors Affecting Perception
• Factors Affecting the Accuracy of Memory
• Gibson's Theory of Direct Perception
• Gregory's Constructivist Theory of Perception
• Gunderson et al 2013 study
• Hughes Policeman Doll Study
• Issues and Debates in Developmental Psychology
• Language and Perception
• McGarrigle and Donaldson Naughty Teddy
• Memory Processes
• Memory recall
• Nature and Nurture in Development
• Normal Distribution Psychology
• Perception Research
• Perceptual Set
• Piagets Theory in Education
• Planning and Conducting Research
• Population Samples
• Primary and Secondary Data
• Quantitative Data
• Quantitative and Qualitative Data
• Quantitative and Qualitative Methods
• Research Procedures
• Serial Position Effect
• Short-term Retention
• Structures of Memory
• Tables, Charts and Graphs
• The Effects of Learning on Development
• The Gilchrist And Nesberg Study Of Motivation
• Three Mountains Task
• Types of Variable
• Types of bias and how to control
• Visual Cues and Constancies
• Visual illusions
• Willingham's Learning Theory
• Cognition and Development
• Cognitive Psychology
• Data Handling and Analysis
• Developmental Psychology
• Eating Behaviour
• Emotion and Motivation
• Famous Psychologists
• Forensic Psychology
• Health Psychology
• Individual Differences Psychology
• Issues and Debates in Psychology
• Personality in Psychology
• Psychological Treatment
• Relationships
• Research Methods in Psychology
• Schizophrenia
• Scientific Foundations of Psychology
• Scientific Investigation
• Sensation and Perception
• Social Context of Behaviour
• Social Psychology
• First, we will discuss the importance of hypotheses in research.
• We will then cover formulating hypotheses in research, including the steps in the formulation of hypotheses in research methodology.
• We will provide examples of hypotheses in research throughout the explanation.
• Finally, we will delve into the different types of hypotheses in research.

What is a Hypothesis?

The current community of psychologists believe that the best approach to understanding behaviour is to conduct scientific research . To be classed as scientific research , it must be observable, valid, reliable and follow a standardised procedure.

One of the important steps in scientific research is to formulate a hypothesis before starting the study procedure.

The hypothesis is a predictive, testable statement predicting the outcome and the results the researcher expects to find.

The hypothesis provides a summary of what direction, if any, is taken to investigate a theory.

In scientific research, there is a criterion that hypotheses need to be met to be regarded as acceptable.

If a hypothesis is disregarded, the research may be rejected by the community of psychology researchers.

Importance of Hypothesis in Research

The purpose of including hypotheses in psychology research is:

• To provide a summary of the research, how it will be investigated, and what is expected to be found.
• To provide an answer to the research question.

When carrying out research, researchers first investigate the research area they are interested in. From this, researchers are required to identify a gap in the literature.

Filling the gap essentially means finding what previous work has not been explained yet, investigated to a sufficient degree, or simply expanding or further investigating a theory if doubt exists.

The researcher then forms a research question that the researcher will attempt to answer in their study.

Remember, the hypothesis is a predictive statement of what is expected to happen when testing the research question.

The hypothesis can be used for later data analysis. This includes inferential tests such as hypothesis testing and identifying if statistical findings are significant.

Steps in the Formulation of Hypothesis in Research Methodology

Researchers must follow certain steps to formulate testable hypotheses when conducting research.

Overall, the researcher has to consider the direction of the research, i.e. will it be looking for a difference caused by independent variables ? Or will it be more concerned with the correlation between variables?

All researchers will likely complete the following.

• Investigating background research in the area of interest.
• Formulating or investigating a theory.
• Identify how the theory will be tested and what the researcher expects to find based on relevant, previously published scientific works.

The above steps are used to formulate testable hypotheses.

The Formulation of Testable Hypotheses

The hypothesis is important in research as it indicates what and how a variable will be investigated.

The hypothesis essentially summarises what and how something will be investigated. This is important as it ensures that the researcher has carefully planned how the research will be done, as the researchers have to follow a set procedure to conduct research.

This is known as the scientific method.

Formulating Hypotheses in Research

When formulating hypotheses, things that researchers should consider are:

Types of Hypotheses in Research

Researchers can propose different types of hypotheses when carrying out research.

The following research scenario will be discussed to show examples of each type of hypothesis that the researchers could use. "A research team was investigating whether memory performance is affected by depression ."

The identified independent variable is the severity of depression scores, and the dependent variable is the scores from a memory performance task.

The null hypothesis predicts that the results will show no or little effect. The null hypothesis is a predictive statement that researchers use when it is thought that the IV will not influence the DV.

In this case, the null hypothesis would be there will be no difference in memory scores on the MMSE test of those who are diagnosed with depression and those who are not.

An alternative hypothesis is a predictive statement used when it is thought that the IV will influence the DV. The alternative hypothesis is also called a non-directional, two-tailed hypothesis, as it predicts the results can go either way, e.g. increase or decrease.

The example in this scenario is there will be an observed difference in scores from a memory performance task between people with high- or low-depressive scores.

The directional alternative hypothesis states how the IV will influence the DV, identifying a specific direction, such as if there will be an increase or decrease in the observed results.

The example in this scenario is people with low depressive scores will perform better in the memory performance task than people who score higher in depressive symptoms.

Example Hypothesis in Research

To summarise, let's look at an example of a straightforward hypothesis that indicates the relationship between two variables: the independent and the dependent.

If you stay up late, you will feel tired the following day; the more caffeine you drink, the harder you find it to fall asleep, or the more sunlight plants get, the taller they will grow.

Formulation of Hypothesis - Key Takeaways

• The current community of psychologists believe that the best approach to understanding behaviour is to conduct scientific research. One of the important steps in scientific research is to create a hypothesis.
• The hypothesis is a predictive, testable statement concerning the outcome/results that the researcher expects to find.
• Hypotheses are needed in research to provide a summary of what the research is, how to investigate a theory and what is expected to be found, and to provide an answer to the research question so that the hypothesis can be used for later data analysis.
• There are requirements for the formulation of testable hypotheses. The hypotheses should identify and operationalise the IV and DV. In addition, they should describe the nature of the relationship between the IV and DV.
• There are different types of hypotheses: Null hypothesis, Alternative hypothesis (this is also known as the non-directional, two-tailed hypothesis), and Directional hypothesis (this is also known as the one-tailed hypothesis).

Flashcards in Formulation of Hypothesis 18

The hypothesis is a predictive, testable statement concerning the outcome/ results the researcher expects to find. 

The scientific method states that researchers need to formulate a good hypothesis before starting the research. 

Directional, alternative hypothesis 

Alternative hypothesis 

A good hypothesis should:

• identify and operationalise the independent and dependent variable
• be testable 
• be falsifiable 
• predictive statements 

All researchers will likely complete the following

• Investigating background research in the area of interest 
• Formulating or investigating a theory 
• Identify how the theory will be tested and what the researcher expects to find based on relevant, previously published scientific works 

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Frequently Asked Questions about Formulation of Hypothesis

What are the 3 types of hypotheses?

The three types of hypotheses are:

• Null hypothesis 
• Alternative hypothesis 
• Directional/non-directional hypothesis 

What is an example of a hypothesis in psychology?

An example of a null hypothesis in psychology is, there will be no observed difference in scores from a memory performance task between people with high- or low-depressive scores.

What are the steps in formulating a hypothesis?

• Investigating background research in the area of interest 
• Formulating or investigating a theory 
• Identify how the theory will be tested and what the researcher expects to find based on relevant, previously published scientific works 

What is formulation of hypothesis in research? 

The formulation of a hypothesis in research is when the researcher formulates a predictive statement of what is expected to happen when testing the research question based on background research.

How to formulate  null and alternative hypothesis?

When formulating a null hypothesis the researcher would state a prediction that they expect to see no difference in the dependent variable when the independent variable changes or is manipulated. Whereas, when using an alternative hypothesis then it would be predicted that there will be a change in the dependent variable. The researcher can state in which direction they expect the results to go. 

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Hypothesis Testing | A Step-by-Step Guide with Easy Examples

Published on November 8, 2019 by Rebecca Bevans . Revised on June 22, 2023.

Hypothesis testing is a formal procedure for investigating our ideas about the world using statistics . It is most often used by scientists to test specific predictions, called hypotheses, that arise from theories.

There are 5 main steps in hypothesis testing:

• State your research hypothesis as a null hypothesis and alternate hypothesis (H o ) and (H a  or H 1 ).
• Collect data in a way designed to test the hypothesis.
• Perform an appropriate statistical test .
• Decide whether to reject or fail to reject your null hypothesis.
• Present the findings in your results and discussion section.

Though the specific details might vary, the procedure you will use when testing a hypothesis will always follow some version of these steps.

Table of contents

Step 1: state your null and alternate hypothesis, step 2: collect data, step 3: perform a statistical test, step 4: decide whether to reject or fail to reject your null hypothesis, step 5: present your findings, other interesting articles, frequently asked questions about hypothesis testing.

After developing your initial research hypothesis (the prediction that you want to investigate), it is important to restate it as a null (H o ) and alternate (H a ) hypothesis so that you can test it mathematically.

The alternate hypothesis is usually your initial hypothesis that predicts a relationship between variables. The null hypothesis is a prediction of no relationship between the variables you are interested in.

• H 0 : Men are, on average, not taller than women. H a : Men are, on average, taller than women.

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For a statistical test to be valid , it is important to perform sampling and collect data in a way that is designed to test your hypothesis. If your data are not representative, then you cannot make statistical inferences about the population you are interested in.

There are a variety of statistical tests available, but they are all based on the comparison of within-group variance (how spread out the data is within a category) versus between-group variance (how different the categories are from one another).

If the between-group variance is large enough that there is little or no overlap between groups, then your statistical test will reflect that by showing a low p -value . This means it is unlikely that the differences between these groups came about by chance.

Alternatively, if there is high within-group variance and low between-group variance, then your statistical test will reflect that with a high p -value. This means it is likely that any difference you measure between groups is due to chance.

Your choice of statistical test will be based on the type of variables and the level of measurement of your collected data .

• an estimate of the difference in average height between the two groups.
• a p -value showing how likely you are to see this difference if the null hypothesis of no difference is true.

Based on the outcome of your statistical test, you will have to decide whether to reject or fail to reject your null hypothesis.

In most cases you will use the p -value generated by your statistical test to guide your decision. And in most cases, your predetermined level of significance for rejecting the null hypothesis will be 0.05 – that is, when there is a less than 5% chance that you would see these results if the null hypothesis were true.

In some cases, researchers choose a more conservative level of significance, such as 0.01 (1%). This minimizes the risk of incorrectly rejecting the null hypothesis ( Type I error ).

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The results of hypothesis testing will be presented in the results and discussion sections of your research paper , dissertation or thesis .

In the results section you should give a brief summary of the data and a summary of the results of your statistical test (for example, the estimated difference between group means and associated p -value). In the discussion , you can discuss whether your initial hypothesis was supported by your results or not.

In the formal language of hypothesis testing, we talk about rejecting or failing to reject the null hypothesis. You will probably be asked to do this in your statistics assignments.

However, when presenting research results in academic papers we rarely talk this way. Instead, we go back to our alternate hypothesis (in this case, the hypothesis that men are on average taller than women) and state whether the result of our test did or did not support the alternate hypothesis.

If your null hypothesis was rejected, this result is interpreted as “supported the alternate hypothesis.”

These are superficial differences; you can see that they mean the same thing.

You might notice that we don’t say that we reject or fail to reject the alternate hypothesis . This is because hypothesis testing is not designed to prove or disprove anything. It is only designed to test whether a pattern we measure could have arisen spuriously, or by chance.

If we reject the null hypothesis based on our research (i.e., we find that it is unlikely that the pattern arose by chance), then we can say our test lends support to our hypothesis . But if the pattern does not pass our decision rule, meaning that it could have arisen by chance, then we say the test is inconsistent with our hypothesis .

If you want to know more about statistics , methodology , or research bias , make sure to check out some of our other articles with explanations and examples.

• Normal distribution
• Descriptive statistics
• Measures of central tendency
• Correlation coefficient

Methodology

• Cluster sampling
• Stratified sampling
• Types of interviews
• Cohort study
• Thematic analysis

Research bias

• Implicit bias
• Cognitive bias
• Survivorship bias
• Availability heuristic
• Nonresponse bias
• Regression to the mean

Hypothesis testing is a formal procedure for investigating our ideas about the world using statistics. It is used by scientists to test specific predictions, called hypotheses , by calculating how likely it is that a pattern or relationship between variables could have arisen by chance.

A hypothesis states your predictions about what your research will find. It is a tentative answer to your research question that has not yet been tested. For some research projects, you might have to write several hypotheses that address different aspects of your research question.

A hypothesis is not just a guess — it should be based on existing theories and knowledge. It also has to be testable, which means you can support or refute it through scientific research methods (such as experiments, observations and statistical analysis of data).

Null and alternative hypotheses are used in statistical hypothesis testing . The null hypothesis of a test always predicts no effect or no relationship between variables, while the alternative hypothesis states your research prediction of an effect or relationship.

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FORMULATING AND TESTING HYPOTHESIS

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Formulating Research Hypothesis and Objective

• First Online: 01 March 2024

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Formulating a research hypothesis and objectives is the first and foremost step in any research process as they provide a clear direction and purpose for your study. In this chapter, we shall learn about formulating an ideal research hypothesis and objectives. Formulation and development of the hypothesis and objectives take place under the following key steps:

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Hazari, A. (2023). Formulating Research Hypothesis and Objective. In: Research Methodology for Allied Health Professionals. Springer, Singapore. https://doi.org/10.1007/978-981-99-8925-6_4

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Formulation of hypothesis may not be necessary in

A. Survey studies

B. Fact finding (historical) studies

C. Normative studies

D. Experimental studies

Answer: Option B

Solution(By Examveda Team)

This Question Belongs to General Knowledge >> Teaching And Research

Join The Discussion

Comments ( 2 ).

Give one example of an ethical issue social researchers need to consider when conducting social research

Example for the fact-finding study is

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