Research Progress in Atopic March Front Immunol. 2020 Aug 27:11:1907. doi: 10.3389/fimmu.2020.01907. eCollection 2020. Authors ... This phenomenon is defined as the "atopic march". Some scholars have suggested that the atopic march does not progress completely in a temporal pattern with genetic and environmental factors. Also, the mechanisms ...
(PDF) Research Progress in Atopic March
Research Progress in Atopic March. Front. Immunol. 11:1907. doi: 10.3389/fimmu.2020.01907. Research Pro gress in Atopic March. Lan Yang 1, Jinrong Fu 1 and Yufeng Zhou 1,2 *
Research Progress in Atopic March
The concept of the atopic march provides a new perspective for the mechanistic research, prediction, prevention, and treatment of atopic diseases. The incidence of allergic diseases continues to rise. Cross-sectional and longitudinal studies have indicated that allergic diseases occur in a time-based order: from atopic dermatitis and food allergy in infancy to gradual development into allergic ...
Revisiting the Atopic March Current Evidence
The concept of the atopic march was originally proposed to describe the typical sequence of progression of childhood allergic disorders, with atopic dermatitis predating the development of asthma and allergic rhinitis ().Data from cohort studies conducted over the past 2 decades has greatly improved our understanding of the natural history of allergic diseases, and there is now a large body of ...
The atopic march
The atopic march is classically thought to be the progression of atopic dermatitis (AD) to other atopic conditions (asthma, allergic rhinitis [AR], food allergy, and eosinophilic esophagitis). The 4 articles1-4 published in this edition of the Annals of Allergy, Asthma & Immunology highlight the risk factors, mechanisms, and heterogeneity in this progression.
Atopic March or Atopic Multimorbidity—Overview of Current Research
The atopic march encompasses a sequence of allergic conditions, including atopic dermatitis, food allergy, allergic rhinitis, and asthma, that frequently develop in a sequential pattern within the same individual. It was introduced as a conceptual framework aimed at elucidating the developmental trajectory of allergic conditions during childhood. Following the introduction of this concept, it ...
Atopic Dermatitis
Atopic dermatitis is a chronic disorder that usually starts in childhood but often persists in adulthood. ... Zhou Y. Research progress in atopic march. Front Immunol 2020;11:1907-1907. Crossref ...
Frontiers
This phenomenon is defined as the "atopic march". Some scholars have suggested that the atopic march does not progress completely in a temporal pattern with genetic and environmental factors. ... the concept of the atopic march provides a new perspective for the mechanistic research, prediction, prevention, and treatment of atopic diseases ...
New Directions in Understanding Atopic March Starting from Atopic
AD often appears early in life, and thus it has been considered as the origin of the atopic march by most prospective longitudinal cohort studies looking at trajectories of allergic diseases [].Prospective longitudinal cohort studies have shown that about 50% of children with AD does not progress into the atopic march, even in its broadest definition [].
Frontiers
In addition, the prevalence of the atopic march differed in distinct countries. Colombian scholars followed up 326 mother-infant pairs in a birth cohort study, and they found that AA was the most common manifestation by 24 months. The prevalence of recurrent AA was 7.1% at 12 months and reached 14.2% at 24 months.
A new paradigm for the Atopic March
A new paradigm for the Atopic March. Published: October 18, 2021. For nearly two decades, the "atopic march" concept, which describes the sequential development of atopic dermatitis (AD), food allergy (FA), asthma, and allergic rhinitis (AR) has served as a guiding principle, however, a recent NIH workshop concluded that only about 3% of ...
(PDF) Current Insights into Atopic March
in infancy with atopic dermatitis and food allergy and develops into allergic asthma and allergic. rhinitis in childhood; the process is defined as "atopic march". Atopic march is caused by ...
Current Insights into Atopic March.
Therefore, preventing the onset of atopic march and its progression at an early stage is crucial. There is an urgent need for progress in research aimed at developing more effective early intervention strategies to ameliorate these sequential atopic disorders.
Research Progress in Atopic March
In addition, the prevalence of the atopic march differed in distinct countries. Colombian scholars followed up 326 mother-infant pairs in a birth cohort study, and they found that AA was the most common manifestation by 24 months. The prevalence of recurrent AA was 7.1% at 12 months and reached 14.2% at 24 months.
The Atopic March and its Prevention.
The Atopic March and its Prevention. Jimenez J 1, Paller AS 1. Author information. Affiliations. 2 authors. 1. Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL. ... Research Progress in Atopic March. Yang L, Fu J, Zhou Y. Front Immunol, 11:1907, 27 Aug 2020 ...
Full article: Efficacy of lebrikizumab in adolescent patients with
Introduction. The worldwide prevalence of atopic dermatitis (AD) in adolescents is approximately 10-15%, with up to 50% suffering from moderate-to-severe disease (Citation 1).AD results in a high disease burden and impaired quality of life (Citation 2-5).The intense pruritus, skin pain, and sleep impairment can impact daily activities and school performance.
Research Progress in Atopic March.
Some studies have shown that the atopic march does not progress completely in a temporal pattern with genes and the environment . Nevertheless, the concept of the atopic march provides a new perspective for the mechanistic research, prediction, prevention, and treatment of allergic diseases.
Apogee Announces Dosing of First Patient in Phase 2 Atopic
The trial was designed to combine the typical Phase 2a and 2b portions of a clinical trial into a single protocol. Part A is expected to enroll approximately 110 patients randomized 2:1 to APG777 ...
Successful use of tralokinumab for the treatment of atopic dermatitis
Notably, the majority of patients exhibited both atopic and non-atopic comorbidities, with two patients experiencing treatment failures with upadacitinib and dupilumab. Following a 16-week treatment period, generalized improvement in disease severity, including the genital area, was evident in 83% ( n = 10) of cases.
Full article: Effect of Chloroquine on Type 2 Inflammatory Response in
Atopic dermatitis (AD) is a common chronic, ... Citation 52 From the results of existing research, it has been manifested that Th2 cell-mediated pruritus, skin barrier dysfunction, and immunity induce a vicious cycle of AD, and on the other hand, IL-4, IL-13, ...
Apogee Therapeutics Highlights Pipeline Progress and Reports First
First Quarter Financial Results. Cash Position: As of March 31, 2024, Apogee had cash, cash equivalents and marketable securities of $816.2 million. Apogee expects that its existing total cash ...
Atopic March or Atopic Multimorbidity—Overview of Current Research
Typically, the atopic march begins with atopic dermatitis (AD) in infancy, followed by the development of allergic asthma and allergic rhinitis as the individual grows older [ 1 ]. Atopic dermatitis emerges in 17-24% of children [ 3 ]. and 10% of adults worldwide [ 4 ]. Among children with mild atopic dermatitis, the prevalence of asthma is ...
Apogee Therapeutics Highlights Pipeline Progress and Reports First
Research & Development (R&D) Expenses: R&D expenses for the first quarter of 2024 were $28.7 million, compared to $8.5 million for the first quarter of 2023. R&D expenses increased primarily due ...
Atopy improves survival and decreases risk of brain metastasis in
Importance: Development of new therapies in melanoma has increased survival, and as a result more patients are living to develop brain metastasis (BrM). Identifying patients at increased risk of BrM is therefore of significant public health importance. Objective: To determine whether history of atopy is associated with improved survival or reduced incidence of BrM in cutaneous melanoma.
Plant-Friendly Microorganisms as a Bio-Barrier Against Pathogens
These microorganisms include opportunistic phytopathogens and non-pathogenic members that may affect the disease's outburst and severity. Improving our knowledge of this research field will have practical benefits and is a vital opening stage for future follow-up studies. Keywords : biological control, crop protection, endophytes, plant ...
COMMENTS
Research Progress in Atopic March Front Immunol. 2020 Aug 27:11:1907. doi: 10.3389/fimmu.2020.01907. eCollection 2020. Authors ... This phenomenon is defined as the "atopic march". Some scholars have suggested that the atopic march does not progress completely in a temporal pattern with genetic and environmental factors. Also, the mechanisms ...
Research Progress in Atopic March. Front. Immunol. 11:1907. doi: 10.3389/fimmu.2020.01907. Research Pro gress in Atopic March. Lan Yang 1, Jinrong Fu 1 and Yufeng Zhou 1,2 *
The concept of the atopic march provides a new perspective for the mechanistic research, prediction, prevention, and treatment of atopic diseases. The incidence of allergic diseases continues to rise. Cross-sectional and longitudinal studies have indicated that allergic diseases occur in a time-based order: from atopic dermatitis and food allergy in infancy to gradual development into allergic ...
The concept of the atopic march was originally proposed to describe the typical sequence of progression of childhood allergic disorders, with atopic dermatitis predating the development of asthma and allergic rhinitis ().Data from cohort studies conducted over the past 2 decades has greatly improved our understanding of the natural history of allergic diseases, and there is now a large body of ...
The atopic march is classically thought to be the progression of atopic dermatitis (AD) to other atopic conditions (asthma, allergic rhinitis [AR], food allergy, and eosinophilic esophagitis). The 4 articles1-4 published in this edition of the Annals of Allergy, Asthma & Immunology highlight the risk factors, mechanisms, and heterogeneity in this progression.
The atopic march encompasses a sequence of allergic conditions, including atopic dermatitis, food allergy, allergic rhinitis, and asthma, that frequently develop in a sequential pattern within the same individual. It was introduced as a conceptual framework aimed at elucidating the developmental trajectory of allergic conditions during childhood. Following the introduction of this concept, it ...
Atopic dermatitis is a chronic disorder that usually starts in childhood but often persists in adulthood. ... Zhou Y. Research progress in atopic march. Front Immunol 2020;11:1907-1907. Crossref ...
This phenomenon is defined as the "atopic march". Some scholars have suggested that the atopic march does not progress completely in a temporal pattern with genetic and environmental factors. ... the concept of the atopic march provides a new perspective for the mechanistic research, prediction, prevention, and treatment of atopic diseases ...
AD often appears early in life, and thus it has been considered as the origin of the atopic march by most prospective longitudinal cohort studies looking at trajectories of allergic diseases [].Prospective longitudinal cohort studies have shown that about 50% of children with AD does not progress into the atopic march, even in its broadest definition [].
In addition, the prevalence of the atopic march differed in distinct countries. Colombian scholars followed up 326 mother-infant pairs in a birth cohort study, and they found that AA was the most common manifestation by 24 months. The prevalence of recurrent AA was 7.1% at 12 months and reached 14.2% at 24 months.
A new paradigm for the Atopic March. Published: October 18, 2021. For nearly two decades, the "atopic march" concept, which describes the sequential development of atopic dermatitis (AD), food allergy (FA), asthma, and allergic rhinitis (AR) has served as a guiding principle, however, a recent NIH workshop concluded that only about 3% of ...
in infancy with atopic dermatitis and food allergy and develops into allergic asthma and allergic. rhinitis in childhood; the process is defined as "atopic march". Atopic march is caused by ...
Therefore, preventing the onset of atopic march and its progression at an early stage is crucial. There is an urgent need for progress in research aimed at developing more effective early intervention strategies to ameliorate these sequential atopic disorders.
In addition, the prevalence of the atopic march differed in distinct countries. Colombian scholars followed up 326 mother-infant pairs in a birth cohort study, and they found that AA was the most common manifestation by 24 months. The prevalence of recurrent AA was 7.1% at 12 months and reached 14.2% at 24 months.
The Atopic March and its Prevention. Jimenez J 1, Paller AS 1. Author information. Affiliations. 2 authors. 1. Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL. ... Research Progress in Atopic March. Yang L, Fu J, Zhou Y. Front Immunol, 11:1907, 27 Aug 2020 ...
Introduction. The worldwide prevalence of atopic dermatitis (AD) in adolescents is approximately 10-15%, with up to 50% suffering from moderate-to-severe disease (Citation 1).AD results in a high disease burden and impaired quality of life (Citation 2-5).The intense pruritus, skin pain, and sleep impairment can impact daily activities and school performance.
Some studies have shown that the atopic march does not progress completely in a temporal pattern with genes and the environment . Nevertheless, the concept of the atopic march provides a new perspective for the mechanistic research, prediction, prevention, and treatment of allergic diseases.
The trial was designed to combine the typical Phase 2a and 2b portions of a clinical trial into a single protocol. Part A is expected to enroll approximately 110 patients randomized 2:1 to APG777 ...
Notably, the majority of patients exhibited both atopic and non-atopic comorbidities, with two patients experiencing treatment failures with upadacitinib and dupilumab. Following a 16-week treatment period, generalized improvement in disease severity, including the genital area, was evident in 83% ( n = 10) of cases.
Atopic dermatitis (AD) is a common chronic, ... Citation 52 From the results of existing research, it has been manifested that Th2 cell-mediated pruritus, skin barrier dysfunction, and immunity induce a vicious cycle of AD, and on the other hand, IL-4, IL-13, ...
First Quarter Financial Results. Cash Position: As of March 31, 2024, Apogee had cash, cash equivalents and marketable securities of $816.2 million. Apogee expects that its existing total cash ...
Typically, the atopic march begins with atopic dermatitis (AD) in infancy, followed by the development of allergic asthma and allergic rhinitis as the individual grows older [ 1 ]. Atopic dermatitis emerges in 17-24% of children [ 3 ]. and 10% of adults worldwide [ 4 ]. Among children with mild atopic dermatitis, the prevalence of asthma is ...
Research & Development (R&D) Expenses: R&D expenses for the first quarter of 2024 were $28.7 million, compared to $8.5 million for the first quarter of 2023. R&D expenses increased primarily due ...
Importance: Development of new therapies in melanoma has increased survival, and as a result more patients are living to develop brain metastasis (BrM). Identifying patients at increased risk of BrM is therefore of significant public health importance. Objective: To determine whether history of atopy is associated with improved survival or reduced incidence of BrM in cutaneous melanoma.
These microorganisms include opportunistic phytopathogens and non-pathogenic members that may affect the disease's outburst and severity. Improving our knowledge of this research field will have practical benefits and is a vital opening stage for future follow-up studies. Keywords : biological control, crop protection, endophytes, plant ...