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10 Free Research and Journal Databases

10 Free Research and Journal Databases

  • 3-minute read
  • 6th April 2019

Finding good research can be tough, especially when so much of it is locked behind paywalls . But there are free resources out there if you know where to look. So to help out, we’ve compiled a list of ten free academic search engines and databases that you should check out.

1. Google Scholar

Even if you’ve not used Google Scholar before, you’ll know Google. And, thus, you can probably guess that Google Scholar is a search engine dedicated to academic work. Not everything listed on Google Scholar will be freely available in full. But it is a good place to start if you’re looking for a specific paper, and many papers can be downloaded for free.

CORE is an open research aggregator. This means it works as a search engine for open access research published by organizations from around the world, all of which is available for free. It is also the world’s largest open access aggregator , so it is a very useful resource for researchers!

Core logo.

3. Bielefeld Academic Search Engine (BASE)

Another dedicated academic search engine, BASE offers access to more than 140 million documents from more than 6,000 sources. Around 60% of these documents are open access, and you can filter results to see only research that is available for free online.

4. Directory of Open Access Journals (DOAJ)

The Directory of Open Access Journals (DOAJ) is a database that lists around 12,000 open access journals covering all areas of science, technology, medicine, social science, and the humanities.

PubMed is a search engine maintained by the NCBI, part of the United States National Library of Medicine. It provides access to more than 29 million citations of biomedical research from MEDLINE, life science journals, and online books. The NCBI runs a similar search engine for research in the chemical sciences called PubChem , too, which is also free to use.

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6. E-Theses Online Service (EThOS)

Run by the British Library, EThOS is a database of over 500,000 doctoral theses. More than half of these are available for free, either directly via EThOS or via a link to a university website.

7. Social Science Research Network (SSRN)

SSRN is a database for research from the social sciences and humanities, including 846,589 research papers from 426,107 researchers across 30 disciplines. Most of these are available for free, although you may need to sign up as a member (also free) to access some services.

8. WorldWideScience

WorldWideScience is a global academic search engine, providing access to national and international scientific databases from across the globe. One interesting feature is that it offers automatic translation, so users can have search results translated into their preferred language.

WorldWideScience logo.

9. Semantic Scholar

Semantic Scholar is an “intelligent” academic search engine. It uses machine learning to prioritize the most important research, which can make it easier to find relevant literature. Or, in Semantic Scholar’s own words, it uses influential citations, images, and key phrases to “cut through the clutter.”

10. Public Library of Science (PLOS)

PLOS is an open-access research organization that publishes several journals. But as well as publishing its own research, PLOS is a dedicated advocate for open-access learning. So if you appreciate the search engines and databases we’ve listed here, check out the rest of the PLOS site to find out more about their campaign to enable access to knowledge.

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The top list of academic search engines

academic search engines

1. Google Scholar

4. science.gov, 5. semantic scholar, 6. baidu scholar, get the most out of academic search engines, frequently asked questions about academic search engines, related articles.

Academic search engines have become the number one resource to turn to in order to find research papers and other scholarly sources. While classic academic databases like Web of Science and Scopus are locked behind paywalls, Google Scholar and others can be accessed free of charge. In order to help you get your research done fast, we have compiled the top list of free academic search engines.

Google Scholar is the clear number one when it comes to academic search engines. It's the power of Google searches applied to research papers and patents. It not only lets you find research papers for all academic disciplines for free but also often provides links to full-text PDF files.

  • Coverage: approx. 200 million articles
  • Abstracts: only a snippet of the abstract is available
  • Related articles: ✔
  • References: ✔
  • Cited by: ✔
  • Links to full text: ✔
  • Export formats: APA, MLA, Chicago, Harvard, Vancouver, RIS, BibTeX

Search interface of Google Scholar

BASE is hosted at Bielefeld University in Germany. That is also where its name stems from (Bielefeld Academic Search Engine).

  • Coverage: approx. 136 million articles (contains duplicates)
  • Abstracts: ✔
  • Related articles: ✘
  • References: ✘
  • Cited by: ✘
  • Export formats: RIS, BibTeX

Search interface of Bielefeld Academic Search Engine aka BASE

CORE is an academic search engine dedicated to open-access research papers. For each search result, a link to the full-text PDF or full-text web page is provided.

  • Coverage: approx. 136 million articles
  • Links to full text: ✔ (all articles in CORE are open access)
  • Export formats: BibTeX

Search interface of the CORE academic search engine

Science.gov is a fantastic resource as it bundles and offers free access to search results from more than 15 U.S. federal agencies. There is no need anymore to query all those resources separately!

  • Coverage: approx. 200 million articles and reports
  • Links to full text: ✔ (available for some databases)
  • Export formats: APA, MLA, RIS, BibTeX (available for some databases)

Search interface of Science.gov

Semantic Scholar is the new kid on the block. Its mission is to provide more relevant and impactful search results using AI-powered algorithms that find hidden connections and links between research topics.

  • Coverage: approx. 40 million articles
  • Export formats: APA, MLA, Chicago, BibTeX

Search interface of Semantic Scholar

Although Baidu Scholar's interface is in Chinese, its index contains research papers in English as well as Chinese.

  • Coverage: no detailed statistics available, approx. 100 million articles
  • Abstracts: only snippets of the abstract are available
  • Export formats: APA, MLA, RIS, BibTeX

Search interface of Baidu Scholar

RefSeek searches more than one billion documents from academic and organizational websites. Its clean interface makes it especially easy to use for students and new researchers.

  • Coverage: no detailed statistics available, approx. 1 billion documents
  • Abstracts: only snippets of the article are available
  • Export formats: not available

Search interface of RefSeek

Consider using a reference manager like Paperpile to save, organize, and cite your references. Paperpile integrates with Google Scholar and many popular databases, so you can save references and PDFs directly to your library using the Paperpile buttons:

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Google Scholar is an academic search engine, and it is the clear number one when it comes to academic search engines. It's the power of Google searches applied to research papers and patents. It not only let's you find research papers for all academic disciplines for free, but also often provides links to full text PDF file.

Semantic Scholar is a free, AI-powered research tool for scientific literature developed at the Allen Institute for AI. Sematic Scholar was publicly released in 2015 and uses advances in natural language processing to provide summaries for scholarly papers.

BASE , as its name suggest is an academic search engine. It is hosted at Bielefeld University in Germany and that's where it name stems from (Bielefeld Academic Search Engine).

CORE is an academic search engine dedicated to open access research papers. For each search result a link to the full text PDF or full text web page is provided.

Science.gov is a fantastic resource as it bundles and offers free access to search results from more than 15 U.S. federal agencies. There is no need any more to query all those resources separately!

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SpringerOpen

The SpringerOpen portfolio has grown tremendously since its launch in 2010, so that we now offer researchers from all areas of science, technology, medicine, the humanities and social sciences a place to publish open access in journals. Publishing with SpringerOpen makes your work freely available online for everyone, immediately upon publication, and our high-level peer-review and production processes guarantee the quality and reliability of the work. Open access books are published by our Springer imprint.

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Get around this paywall in a flash: DOI: 10.1126/science.196.4287.293 URL: http://science.sciencemag.org/content/196/4287/293/tab-pdf PMC (Pubmed Central) ID: PMC4167664 Pubmed ID: 17756097 Title: Ribulose bisphosphate carboxylase: a two-layered, square-shaped molecule of symmetry 422 Citation: Baker, T. S., Eisenberg, D., & Eiserling, F. (1977). Ribulose Bisphosphate Carboxylase: A Two-Layered, Square-Shaped Molecule of Symmetry 422. Science, 196(4287), 293-295. doi:10.1126/science.196.4287.293 or try your favourite citation format (Harvard, Bibtex, etc).

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How to Write a Research Paper | A Beginner's Guide

A research paper is a piece of academic writing that provides analysis, interpretation, and argument based on in-depth independent research.

Research papers are similar to academic essays , but they are usually longer and more detailed assignments, designed to assess not only your writing skills but also your skills in scholarly research. Writing a research paper requires you to demonstrate a strong knowledge of your topic, engage with a variety of sources, and make an original contribution to the debate.

This step-by-step guide takes you through the entire writing process, from understanding your assignment to proofreading your final draft.

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Table of contents

Understand the assignment, choose a research paper topic, conduct preliminary research, develop a thesis statement, create a research paper outline, write a first draft of the research paper, write the introduction, write a compelling body of text, write the conclusion, the second draft, the revision process, research paper checklist, free lecture slides.

Completing a research paper successfully means accomplishing the specific tasks set out for you. Before you start, make sure you thoroughly understanding the assignment task sheet:

  • Read it carefully, looking for anything confusing you might need to clarify with your professor.
  • Identify the assignment goal, deadline, length specifications, formatting, and submission method.
  • Make a bulleted list of the key points, then go back and cross completed items off as you’re writing.

Carefully consider your timeframe and word limit: be realistic, and plan enough time to research, write, and edit.

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There are many ways to generate an idea for a research paper, from brainstorming with pen and paper to talking it through with a fellow student or professor.

You can try free writing, which involves taking a broad topic and writing continuously for two or three minutes to identify absolutely anything relevant that could be interesting.

You can also gain inspiration from other research. The discussion or recommendations sections of research papers often include ideas for other specific topics that require further examination.

Once you have a broad subject area, narrow it down to choose a topic that interests you, m eets the criteria of your assignment, and i s possible to research. Aim for ideas that are both original and specific:

  • A paper following the chronology of World War II would not be original or specific enough.
  • A paper on the experience of Danish citizens living close to the German border during World War II would be specific and could be original enough.

Note any discussions that seem important to the topic, and try to find an issue that you can focus your paper around. Use a variety of sources , including journals, books, and reliable websites, to ensure you do not miss anything glaring.

Do not only verify the ideas you have in mind, but look for sources that contradict your point of view.

  • Is there anything people seem to overlook in the sources you research?
  • Are there any heated debates you can address?
  • Do you have a unique take on your topic?
  • Have there been some recent developments that build on the extant research?

In this stage, you might find it helpful to formulate some research questions to help guide you. To write research questions, try to finish the following sentence: “I want to know how/what/why…”

A thesis statement is a statement of your central argument — it establishes the purpose and position of your paper. If you started with a research question, the thesis statement should answer it. It should also show what evidence and reasoning you’ll use to support that answer.

The thesis statement should be concise, contentious, and coherent. That means it should briefly summarize your argument in a sentence or two, make a claim that requires further evidence or analysis, and make a coherent point that relates to every part of the paper.

You will probably revise and refine the thesis statement as you do more research, but it can serve as a guide throughout the writing process. Every paragraph should aim to support and develop this central claim.

Receive feedback on language, structure, and formatting

Professional editors proofread and edit your paper by focusing on:

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A research paper outline is essentially a list of the key topics, arguments, and evidence you want to include, divided into sections with headings so that you know roughly what the paper will look like before you start writing.

A structure outline can help make the writing process much more efficient, so it’s worth dedicating some time to create one.

Your first draft won’t be perfect — you can polish later on. Your priorities at this stage are as follows:

  • Maintaining forward momentum — write now, perfect later.
  • Paying attention to clear organization and logical ordering of paragraphs and sentences, which will help when you come to the second draft.
  • Expressing your ideas as clearly as possible, so you know what you were trying to say when you come back to the text.

You do not need to start by writing the introduction. Begin where it feels most natural for you — some prefer to finish the most difficult sections first, while others choose to start with the easiest part. If you created an outline, use it as a map while you work.

Do not delete large sections of text. If you begin to dislike something you have written or find it doesn’t quite fit, move it to a different document, but don’t lose it completely — you never know if it might come in useful later.

Paragraph structure

Paragraphs are the basic building blocks of research papers. Each one should focus on a single claim or idea that helps to establish the overall argument or purpose of the paper.

Example paragraph

George Orwell’s 1946 essay “Politics and the English Language” has had an enduring impact on thought about the relationship between politics and language. This impact is particularly obvious in light of the various critical review articles that have recently referenced the essay. For example, consider Mark Falcoff’s 2009 article in The National Review Online, “The Perversion of Language; or, Orwell Revisited,” in which he analyzes several common words (“activist,” “civil-rights leader,” “diversity,” and more). Falcoff’s close analysis of the ambiguity built into political language intentionally mirrors Orwell’s own point-by-point analysis of the political language of his day. Even 63 years after its publication, Orwell’s essay is emulated by contemporary thinkers.

Citing sources

It’s also important to keep track of citations at this stage to avoid accidental plagiarism . Each time you use a source, make sure to take note of where the information came from.

You can use our free citation generators to automatically create citations and save your reference list as you go.

APA Citation Generator MLA Citation Generator

The research paper introduction should address three questions: What, why, and how? After finishing the introduction, the reader should know what the paper is about, why it is worth reading, and how you’ll build your arguments.

What? Be specific about the topic of the paper, introduce the background, and define key terms or concepts.

Why? This is the most important, but also the most difficult, part of the introduction. Try to provide brief answers to the following questions: What new material or insight are you offering? What important issues does your essay help define or answer?

How? To let the reader know what to expect from the rest of the paper, the introduction should include a “map” of what will be discussed, briefly presenting the key elements of the paper in chronological order.

The major struggle faced by most writers is how to organize the information presented in the paper, which is one reason an outline is so useful. However, remember that the outline is only a guide and, when writing, you can be flexible with the order in which the information and arguments are presented.

One way to stay on track is to use your thesis statement and topic sentences . Check:

  • topic sentences against the thesis statement;
  • topic sentences against each other, for similarities and logical ordering;
  • and each sentence against the topic sentence of that paragraph.

Be aware of paragraphs that seem to cover the same things. If two paragraphs discuss something similar, they must approach that topic in different ways. Aim to create smooth transitions between sentences, paragraphs, and sections.

The research paper conclusion is designed to help your reader out of the paper’s argument, giving them a sense of finality.

Trace the course of the paper, emphasizing how it all comes together to prove your thesis statement. Give the paper a sense of finality by making sure the reader understands how you’ve settled the issues raised in the introduction.

You might also discuss the more general consequences of the argument, outline what the paper offers to future students of the topic, and suggest any questions the paper’s argument raises but cannot or does not try to answer.

You should not :

  • Offer new arguments or essential information
  • Take up any more space than necessary
  • Begin with stock phrases that signal you are ending the paper (e.g. “In conclusion”)

There are four main considerations when it comes to the second draft.

  • Check how your vision of the paper lines up with the first draft and, more importantly, that your paper still answers the assignment.
  • Identify any assumptions that might require (more substantial) justification, keeping your reader’s perspective foremost in mind. Remove these points if you cannot substantiate them further.
  • Be open to rearranging your ideas. Check whether any sections feel out of place and whether your ideas could be better organized.
  • If you find that old ideas do not fit as well as you anticipated, you should cut them out or condense them. You might also find that new and well-suited ideas occurred to you during the writing of the first draft — now is the time to make them part of the paper.

The goal during the revision and proofreading process is to ensure you have completed all the necessary tasks and that the paper is as well-articulated as possible. You can speed up the proofreading process by using the AI proofreader .

Global concerns

  • Confirm that your paper completes every task specified in your assignment sheet.
  • Check for logical organization and flow of paragraphs.
  • Check paragraphs against the introduction and thesis statement.

Fine-grained details

Check the content of each paragraph, making sure that:

  • each sentence helps support the topic sentence.
  • no unnecessary or irrelevant information is present.
  • all technical terms your audience might not know are identified.

Next, think about sentence structure , grammatical errors, and formatting . Check that you have correctly used transition words and phrases to show the connections between your ideas. Look for typos, cut unnecessary words, and check for consistency in aspects such as heading formatting and spellings .

Finally, you need to make sure your paper is correctly formatted according to the rules of the citation style you are using. For example, you might need to include an MLA heading  or create an APA title page .

Scribbr’s professional editors can help with the revision process with our award-winning proofreading services.

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Checklist: Research paper

I have followed all instructions in the assignment sheet.

My introduction presents my topic in an engaging way and provides necessary background information.

My introduction presents a clear, focused research problem and/or thesis statement .

My paper is logically organized using paragraphs and (if relevant) section headings .

Each paragraph is clearly focused on one central idea, expressed in a clear topic sentence .

Each paragraph is relevant to my research problem or thesis statement.

I have used appropriate transitions  to clarify the connections between sections, paragraphs, and sentences.

My conclusion provides a concise answer to the research question or emphasizes how the thesis has been supported.

My conclusion shows how my research has contributed to knowledge or understanding of my topic.

My conclusion does not present any new points or information essential to my argument.

I have provided an in-text citation every time I refer to ideas or information from a source.

I have included a reference list at the end of my paper, consistently formatted according to a specific citation style .

I have thoroughly revised my paper and addressed any feedback from my professor or supervisor.

I have followed all formatting guidelines (page numbers, headers, spacing, etc.).

You've written a great paper. Make sure it's perfect with the help of a Scribbr editor!

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How to Write a Research Paper (+ Free AI Research Paper Writer)

How to Write a Research Paper (+ Free AI Research Paper Writer)

Table of contents

is research paper free

Meredith Sell

Over the years, I've managed to vastly improve how I write research papers.

The three major game-changers for me, in terms of quality of the finished piece, have been:

  • Following the research paper checklist (see below)
  • Developing the thesis before starting to write
  • And, more recently, using AI to improve my research paper draft

Let's break down each of these elements and produce the kind of research papers that get cited in magazines.

FREE AI research paper writer > FREE AI research paper writer >

Write your research paper with the help of AI

What is a research paper, and how is it written differently?

Research papers are longer and more in-depth than essays. They require extensive research and evidence-based arguments. Research papers also typically have a more formal structure and require citations and references.When academics want to find a balanced and comprehensive view on a given topic, they usually seek a research paper.

Like most writing assignments, a research paper can be broken down into simple steps. Research papers follow the same basic writing process as explanatory or persuasive essays — but instead of making an argument or drawing greater meaning from the topic, the research paper is primarily concerned with concrete facts that may be analyzed, examined, or interpreted to better understand the paper’s central topic.

This is good news if you enjoy research: you’ll be doing a lot of it. The ultimate quality of your paper depends on you conducting thorough, complete research — and relying on reputable sources.

How to Properly Write a Research Paper Using AI

1. make a checklist based on the assignment description, and fill it out with ai.

Your professor has likely specified some criteria for your research paper:

  • Length (in pages or words)
  • Type of topic (the War of 1812, ancient Greece, agriculture, etc.)
  • Elements that must be included, such as analysis, discussion, and comparison.
  • Types of sources you must draw from (academic papers, encyclopedias, etc.)
  • Source attribution style
  • Formatting style

Go through the assignment description and create a checklist of those criteria. You can use this checklist throughout the research and writing process as well:

research paper checklist

AI can really help you get some traction with your research paper in the preperation stage. This includes two main steps:

  • Brainstorming paper topic idea
  • Outlining based on your topic, basing the prompt on the assignment

2. Choose a topic you’re curious about, or use AI to help you with that

A sure way to write a boring research paper is to pick a topic you have no interest in, like summer temperatures in the desert or the life cycle of a flea. (Though someone’s probably interested in those things.)

Instead, follow your curiosity.

If your paper is for a writing class, you may have a lot of freedom to choose what you write about, so tap into your interests. Are you intrigued by the history of roller skating or the invention of the soccer cleat? Or how teen social dynamics have changed with evolving technology (think: home phones → online instant messaging → flip phones → smartphones)?

If you’re writing for a class in a subject like history, art, or science, you’ll probably have more restrictions on what you can write about — like a time period or type of art or science — but you can still use your curiosity to pick an interesting topic.

If you’re having a tough time, try brainstorming a list of things you’ve wondered about. Ask “ what’s up with… ” and see what comes to mind.

For example:

What’s up with traffic circles and why are they supposedly better for traffic patterns than a light or four-way stop?

What’s up with country music sounding more and more like hip-hop?

What’s up with people who have gluten allergies being able to eat bread in Europe but not the US?

Once you have a list, choose the topic you find most interesting (and appropriate for the assignment).

If your mind draws a blank, you can utilize AI to help you choose a topic. Let's say your course is about mid century art. You can go to a tool like Wotdtune and ask it to give you ideas for creative mid century art essays. See example below.

is research paper free

3. Develop your thesis (and guide your research) by asking a research question

Even though a research paper may not necessarily take a side on a topic, it still needs a thesis, aka a central idea or focus that drives the piece from beginning to end. 

We wrote a whole guide on writing thesis statements , so here we’ll just give you this tip:

Use a research question to develop your thesis

A research question is a variation on the “What’s up with…” questions from the last tip — but it will zoom in more specifically on the aspect of your topic that you’re investigating.

Why were the Irish so dependent on potatoes?

Did any women in ancient Greece enjoy relative freedom and autonomy?

You may already know the answer to these questions, or you may not. Either way, they give you a place to start in your research. Once you have your question, set out to:

  • Find the initial answer.
  • Gather more context (the who, what, when, where, why, how) around that answer.
  • Revise your research question and turn it into your thesis.

This process helps tighten your focus from a broad topic that could fill books to a specific angle that can be meaningfully explored in the few pages of your paper.

Instead of the potato famine , write about why England was to blame for the potato famine’s devastating effects on the Irish.

Instead of ancient Greece or women in ancient Greece , write about how Spartan women’s lives differed from the lives of women in Athens.

4. Skim sources and use AI to perform research for your paper

Your research question can help you quickly determine whether information is relevant to your paper. As you gather initial sources, skim them — and then use your research question to decide whether to keep or discard the source. 

Does the source cover information relevant to my research question?

Yes: Keep to read later.

No: Discard and move on to the next source.

This approach will save you precious research time. You won’t waste limited hours reading sources that don’t have a single helpful fact.

If skimming is hard for you (as a deep reader, I get it), Wordtune can help. Paste the link to your online source, upload a scanned PDF, or copy the text, and the tool will scan and summarize for you. You can always come back later and closely read the most useful sources.

Wordtune Read reading an argument about dangerous fungus

5. Make note of the most interesting facts you find

Along with taking detailed notes of your research (complete with all the source info you need to make proper citations), highlight the most interesting facts you come across. You could stick these in a section together or mark them in a way that makes them stand out.

Why should you do this?

Because later on, one of these fascinating factoids could have a direct connection to your thesis — and make a great hook for the start of your paper. Instead of digging through all of your notes to try to remember what that interesting tidbit was, you’ll be able to find it easily.

6. Organize your research

There are plenty of ways to organize your notes, but I suggest breaking them up into subtopics and categories.

  • Subtopic: A topic related to your main topic or thesis that needs to be explained and understood by readers in order to understand your main topic or thesis. For example: Land ownership in Ireland under British rule.
  • Category: An overarching concept that several subtopics fall under. For example: British restrictions on the Irish.

To start, I would focus on the subtopics and then group them into categories.

As you organize, use the formatting tools in your word processor to tag headings and subheadings. For example, all categories would be an H2 (Heading 2), while all subtopics would be an H3 (Heading 3). 

Screenshot of Google Docs style tagging.

Tagging your categories and subtopics this way will help you develop your outline. Just organize your categories and subtopics in a logical order, and you’ll have a skeleton of an outline ready to go.

7. Write with your research document open

No one can remember everything they found while researching — you’ll need to reference your research document throughout the writing process. No question there.

But you can make this easier (and keep your writing process efficient) by:

Keeping your research document open and in clear view.

I like to put my draft document and my research document side by side on my screen, so I can see them both at the same time. 

Another approach would be to paste the information you need directly into your draft document — in the order you’ll need it. (Your outline will help you know what you need.)

8. Steal the TK trick from journalists

In the middle of drafting your paper, you find that you’re missing a fact. 

You neglected to write down how many Irish people starved due to the potato famine.

You don’t know what age Spartan women were able to own property.

Instead of derailing your writing and searching for that information, write the sentence you want to write and stick a “TK” where the missing fact should go.

“TK” stands for “to come” (don't ask us why) and is a placeholder used by journalists to mark missing information they’ll fill in later. Using TK allows you to keep writing without getting off track every time you discover your research didn’t cover everything.

A whopping TK Irish people starved, thanks to the combination of famine and British oppression.

At age TK , Spartan girls became women who were able to own property, a right that their sisters in Athens did not enjoy.

9. Revise, explain, paraphrase with AI as your research/writing assistant

Using the right researching tools can get you a lot way.

If you’re ever at a loss for words — writing clunky, clumsy sentences, struggling to explain a concept, or having a hard time paraphrasing a source — Wordtune can serve as your AI sidekick.  

Simply highlight the sentence in question and browse Wordtune’s suggestion for a better wording.

Using Wordtune for research papers

You can also use Wordtune Spices to come up with examples and counter arguments for whatever you're writing about or even find stats and facts, complete with source citations

A great feature for academics

Wordtune doesn’t do all of the writing for you, but it can help you sharpen your ideas on the sentence level, so you can hand in a research paper with good writing that’s still very much your own.

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  • ACS Publications

Call for Papers: Applications of Free-Energy Calculations to Biomolecular Processes

  • Apr 9, 2024

This joint Virtual Special Issue aims to promote cutting-edge research that applies free-energy calculations to the investigation of biomolecular processes. Submit your manuscript by October 31, 2024.

Microscopic view of plant cells showing chloroplasts in various shades of green and blue.

Building upon a recently published Collection of influential articles published in the Journal of Chemical Information and Modeling and in The Journal of Physical Chemistry B , we are pleased to announce a joint Virtual Special Issue (VSI) aimed at promoting cutting-edge research that applies free-energy calculations to the investigation of biomolecular processes. Researchers are encouraged to submit a manuscript describing their new and unpublished work by  October 31, 2024.

We welcome submissions that fall within the scientific scope of the two journals, reporting original methodological developments, as well as extensions, or applications thereof, which have allowed discoveries to be made, and new physical insights to be gained. Research areas of particular interest to the proposed Journal of Chemical Information and Modeling and The Journal of Physical Chemistry B joint VSI include, but are not limited to:

  • Alchemical Free-Energy Calculations for Drug Discovery
  • Methodological Developments for Free-Energy Calculations
  • Machine Learning and Free-Energy Calculations
  • Protein-Protein Interactions
  • Free Energies Determined from QM/MM and Reactive MD Simulations

Organizing Editors

Prof. Zoe Cournia , Executive Editor, Journal of Chemical Information and Modeling Academy of Athens, Greece

Prof. Christophe Chipot , Senior Editor, The Journal of Physical Chemistry A/B/C CNRS, France

Submission Instructions

Just like any submission to either the Journal of Chemical Information and Modeling or The Journal of Physical Chemistry B , contributions should consist of original research of sufficient broad interest, providing new physical insight, or reporting novel methodological developments. The contributions received by either journal will be peer reviewed with the same standards as any regular submission.

To ensure an unbiased peer-review process, the journals ask that you do not indicate within your manuscript that the submission is intended for the VSI. If you do, your manuscript will be returned for correction. Instead, when you submit your manuscript, please state prominently in the cover letter for the submission that the paper is intended for the “Applications of Free-Energy Calculations to Biomolecular Processes” VSI. For submissions to JCIM , you can select “Applications of Free-Energy Calculations to Biomolecular Processes” from the drop down list of Special Issues list.

You can find a complete list of sections and other important information for authors in The Journal of Physical Chemistry B or Journal of Chemical Information and Modeling Author Guidelines.

Contributing to this Virtual Special Issue

If you are unsure if your research is within the scope of this VSI or have other questions about submitting a manuscript to the journal please email The Journal of Physical Chemistry EIC office or the Journal of Chemical Information and Modeling EIC office .

Open Access

There are diverse open-access options for publications in American Chemical Society journals. Please visit our Open Science Resource Center for more information.

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