Case series: an essential study design to build knowledge and pose
Case series is also an appropriate study design to describe new treatments, previously unknown medication adverse events, and rare diseases. 2 METHODOLOGY AND QUALITY OF CASE SERIES STUDIES Inclusion criteria - A precise operational definition of a "case" is crucial for the reliability of the study.
How to design a good case series
Reproducibility of Results. Research Design*. A case series is a descriptive study that follows a group of patients who have a similar diagnosis or who are undergoing the same procedure over a certain period of time. As there is no experimental protocol or control for allocation of patients to treatment, surgeons and patients decide on whether ….
Case series: Design, measures, and classic example
Case series is one of the most common studies performed in medical research and provides the foundation for many more rigorous research studies. The primary outcome of a case series is a testable hypothesis that may be further evaluated with a more rigorous study design. Benefits of case series include their relative inexpensive nature, smaller ...
Case Reports, Case Series
Editorial. Introduction. Case reports and case series or case study research are descriptive studies to present patients in their natural clinical setting. Case reports, which generally consist of three or fewer patients, are prepared to illustrate features in the practice of medicine and potentially create new research questions that may contribute to the acquisition of additional knowledge ...
Case series: design, measures, and classic example
Although case series can be done prospectively, most are done retrospectively and are subject to incomplete data collection. Like other observational studies, case series are prone to measurement and selection bias. 2. Get started: Writing case series Design of case series. A case series should be longitudinal with a clearly defined timeline ...
Case series: design, measures, classic example
Using these examples as a template, we will outline the steps involved in approaching case series design. ... Research team. A case series is a retrospective review of patient data and therefore does not typically require an extensive research team for the execution of the study. While a case series could in theory be conducted by a single ...
Case Studies/ Case Report/ Case Series
A case study, also known as a case report, is an in depth or intensive study of a single individual or specific group, while a case series is a grouping of similar case studies / case reports together. A case study / case report can be used in the following instances: where there is atypical or abnormal behaviour or development.
Design of a Clinical Case Series
A case series is a descriptive study that follows a group of patients with the same diagnosis or exposure (clinical treatment or surgical intervention) over a defined period of time [].This study design is helpful in providing details regarding novel interventions, interventions for rare diseases, and describing adverse events following interventions.
Case series
A case series (also known as a clinical series) is a type of medical research study that tracks subjects with a known exposure, such as patients who have received a similar treatment, [1] or examines their medical records for exposure and outcome. Case series may be consecutive [2] or non-consecutive, [3] depending on whether all cases presenting to the reporting authors over a period were ...
A critical guide to case series reports
Abstract. Objective: Provide guidance to investigators and authors regarding appropriate conduct and reporting of case-series studies. Summary of background data: Evidence-based practice has provided a substantial contribution to advancing clinical science. Many study designs have been critically examined, and the quality of the research ...
Methodological quality of case series studies: an introduction to the
Results: The JBI critical appraisal tool for case series studies includes 10 questions addressing the internal validity and risk of bias of case series designs, particularly confounding, selection, and information bias, in addition to the importance of clear reporting. Conclusion: In certain situations, case series designs may represent the ...
Methodological quality of case series studies: an introducti ...
An international working group was formed to review the methodological literature regarding case series as a form of evidence for inclusion in systematic reviews. The group then developed a critical appraisal tool based on the epidemiological literature relating to bias within these studies. This was then piloted, reviewed, and approved by JBI ...
Case series: design, measures, and an example
Abstract. Developing an effective research plan begins with choosing an appropriate study design. Case series can serve as a powerful method to report novel and unique findings in peer-reviewed journals. Case series are included in the group of descriptive studies. Case series are ideal for studies recognizing new diseases, detecting uncommon ...
How to Write Case Reports and Case Series
A case report describes several aspects of an individual patient's presentation, investigations, management decisions, and/or outcomes. This is a type of observational study and has been described as the smallest publishable unit in medical literature. A case series involves a group of patients with similar presentations or treatments.
The Case Time Series Design
Extension to test and relax these strong assumptions have been developed for the self-controlled case series design, 27,28 but further research is needed to implement and assess their validity in case time series models. Conversely, the new design is well suited to control for temporal confounding that can invalidate the assumption of constant ...
Case Reports and Case Series
Case reports and case series are descriptive studies that recount a patient scenario complete with pertinent medical information such as laboratory values, medications, and diagnoses. 1,2 A case report includes a detailed discussion of a unique medical scenario of a single case or event in light of the currently available literature and provides an evaluation of the findings. 3 Case series ...
Self controlled case series methods: an alternative to standard
The self controlled case series (SCCS) method is an epidemiological study design for which individuals act as their own control—ie, comparisons are made within individuals. Hence, only individuals who have experienced an event are included and all time invariant confounding is eliminated. The temporal association between a transient exposure and an event is estimated. SCCS was originally ...
Clarifying the distinction between case series and cohort studies in
One key design feature to classify observational study designs is to distinguish comparative from non-comparative studies ... Case series: Patients with a particular disease or disease-related outcome are sampled. Case series exist in 2 types: ... In research areas in which randomized controlled trials or large planned prospective and well ...
Case series: Design, measures, and classic example
Case series is one of the most common studies performed in medical research and provides the foundation for many more rigorous research studies. The primary outcome of a case series is a testable hypothesis that may be further evaluated with a more rigorous study design. Benefits of case series include their relative inexpensive nature, smaller ...
Methodology: How to develop a case report or case series report
Abstract. Case reports or case series reports are descriptive studies, although their results are not used to make inferences, they are the first line of evidence for new therapies and a preamble to research with a stronger methodological design. This type of study is essential to describe new or unusual diseases, adverse events, or ...
Clinical "case series": a concept analysis
The concept of "case series" is not well defined in the literature and does not reflect a specific research design. We suggest that a case series should have more than four patients while four paitents or less should be reported individually as case reports. Keywords: ... Some journals will accept only a case series design but not a case ...
Case series: design, measures, and classic example
Case series are observational reports without analysis. They are uncontrolled, anecdotal reports of uncommon or novel cases in individuals or groups of patients. Although case series fall low on the hierarchy of evidence, they are clinically important as they can highlight an unrecognized outcome or a novel mechanism, diagnosis, or treatment.
Case series: an essential study design to build knowledge and pose
Case series: an essential study design to build knowledge and pose hypotheses for rare and new diseases. ... Methods in Epidemiologic, Clinical, and Operations Research-MECOR-program, American Thoracic Society/Asociación Latinoamericana del Tórax, Montevideo, Uruguay. 2. CINEUMO Research Center, Fundación Neumológica Colombiana, Bogota ...
COMMENTS
Case series is also an appropriate study design to describe new treatments, previously unknown medication adverse events, and rare diseases. 2 METHODOLOGY AND QUALITY OF CASE SERIES STUDIES Inclusion criteria - A precise operational definition of a "case" is crucial for the reliability of the study.
Reproducibility of Results. Research Design*. A case series is a descriptive study that follows a group of patients who have a similar diagnosis or who are undergoing the same procedure over a certain period of time. As there is no experimental protocol or control for allocation of patients to treatment, surgeons and patients decide on whether ….
Case series is one of the most common studies performed in medical research and provides the foundation for many more rigorous research studies. The primary outcome of a case series is a testable hypothesis that may be further evaluated with a more rigorous study design. Benefits of case series include their relative inexpensive nature, smaller ...
Editorial. Introduction. Case reports and case series or case study research are descriptive studies to present patients in their natural clinical setting. Case reports, which generally consist of three or fewer patients, are prepared to illustrate features in the practice of medicine and potentially create new research questions that may contribute to the acquisition of additional knowledge ...
Although case series can be done prospectively, most are done retrospectively and are subject to incomplete data collection. Like other observational studies, case series are prone to measurement and selection bias. 2. Get started: Writing case series Design of case series. A case series should be longitudinal with a clearly defined timeline ...
Using these examples as a template, we will outline the steps involved in approaching case series design. ... Research team. A case series is a retrospective review of patient data and therefore does not typically require an extensive research team for the execution of the study. While a case series could in theory be conducted by a single ...
A case study, also known as a case report, is an in depth or intensive study of a single individual or specific group, while a case series is a grouping of similar case studies / case reports together. A case study / case report can be used in the following instances: where there is atypical or abnormal behaviour or development.
A case series is a descriptive study that follows a group of patients with the same diagnosis or exposure (clinical treatment or surgical intervention) over a defined period of time [].This study design is helpful in providing details regarding novel interventions, interventions for rare diseases, and describing adverse events following interventions.
A case series (also known as a clinical series) is a type of medical research study that tracks subjects with a known exposure, such as patients who have received a similar treatment, [1] or examines their medical records for exposure and outcome. Case series may be consecutive [2] or non-consecutive, [3] depending on whether all cases presenting to the reporting authors over a period were ...
Abstract. Objective: Provide guidance to investigators and authors regarding appropriate conduct and reporting of case-series studies. Summary of background data: Evidence-based practice has provided a substantial contribution to advancing clinical science. Many study designs have been critically examined, and the quality of the research ...
Results: The JBI critical appraisal tool for case series studies includes 10 questions addressing the internal validity and risk of bias of case series designs, particularly confounding, selection, and information bias, in addition to the importance of clear reporting. Conclusion: In certain situations, case series designs may represent the ...
An international working group was formed to review the methodological literature regarding case series as a form of evidence for inclusion in systematic reviews. The group then developed a critical appraisal tool based on the epidemiological literature relating to bias within these studies. This was then piloted, reviewed, and approved by JBI ...
Abstract. Developing an effective research plan begins with choosing an appropriate study design. Case series can serve as a powerful method to report novel and unique findings in peer-reviewed journals. Case series are included in the group of descriptive studies. Case series are ideal for studies recognizing new diseases, detecting uncommon ...
A case report describes several aspects of an individual patient's presentation, investigations, management decisions, and/or outcomes. This is a type of observational study and has been described as the smallest publishable unit in medical literature. A case series involves a group of patients with similar presentations or treatments.
Extension to test and relax these strong assumptions have been developed for the self-controlled case series design, 27,28 but further research is needed to implement and assess their validity in case time series models. Conversely, the new design is well suited to control for temporal confounding that can invalidate the assumption of constant ...
Case reports and case series are descriptive studies that recount a patient scenario complete with pertinent medical information such as laboratory values, medications, and diagnoses. 1,2 A case report includes a detailed discussion of a unique medical scenario of a single case or event in light of the currently available literature and provides an evaluation of the findings. 3 Case series ...
The self controlled case series (SCCS) method is an epidemiological study design for which individuals act as their own control—ie, comparisons are made within individuals. Hence, only individuals who have experienced an event are included and all time invariant confounding is eliminated. The temporal association between a transient exposure and an event is estimated. SCCS was originally ...
One key design feature to classify observational study designs is to distinguish comparative from non-comparative studies ... Case series: Patients with a particular disease or disease-related outcome are sampled. Case series exist in 2 types: ... In research areas in which randomized controlled trials or large planned prospective and well ...
Case series is one of the most common studies performed in medical research and provides the foundation for many more rigorous research studies. The primary outcome of a case series is a testable hypothesis that may be further evaluated with a more rigorous study design. Benefits of case series include their relative inexpensive nature, smaller ...
Abstract. Case reports or case series reports are descriptive studies, although their results are not used to make inferences, they are the first line of evidence for new therapies and a preamble to research with a stronger methodological design. This type of study is essential to describe new or unusual diseases, adverse events, or ...
The concept of "case series" is not well defined in the literature and does not reflect a specific research design. We suggest that a case series should have more than four patients while four paitents or less should be reported individually as case reports. Keywords: ... Some journals will accept only a case series design but not a case ...
Case series are observational reports without analysis. They are uncontrolled, anecdotal reports of uncommon or novel cases in individuals or groups of patients. Although case series fall low on the hierarchy of evidence, they are clinically important as they can highlight an unrecognized outcome or a novel mechanism, diagnosis, or treatment.
Case series: an essential study design to build knowledge and pose hypotheses for rare and new diseases. ... Methods in Epidemiologic, Clinical, and Operations Research-MECOR-program, American Thoracic Society/Asociación Latinoamericana del Tórax, Montevideo, Uruguay. 2. CINEUMO Research Center, Fundación Neumológica Colombiana, Bogota ...