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Grants & funding.

The National Institutes of Health is the largest public funder of biomedical research in the world. In fiscal year 2022, NIH invested most of its $45 billion appropriations in research seeking to enhance life, and to reduce illness and disability. NIH-funded research has led to breakthroughs and new treatments helping people live longer, healthier lives, and building the research foundation that drives discovery.

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Home > Grants > Research Grants

Research Grants

NIHCM Foundation supports innovative, independent, investigator-initiated research with a high potential to inform improvements to the United States health care system.

Grants provide funding for:

• Projects that advance the evidence-base in areas such as health care financing, affordability, delivery, management and/or policy

Application Information

We are now accepting letters of inquiry for the 2024-2025 funding cycle of NIHCM Foundation's investigator-initiated research grant program. Building on our long-standing commitment to objective research, NIHCM will make up to $500,000 available to new and existing grantees.

Winning research studies will be selected using the following process:

• Interested researchers must submit a brief letter of inquiry (LOI) outlining their study idea by 5:00 PM EDT on June 28, 2024 . Applications are welcome at any time prior to that deadline. LOIs must conform to the required structure and must be submitted using NIHCM’s online entry system (see below).
• Full (10-page) proposals will be invited from a small number of applicants in August and will be due in September 2024.
• NIHCM will notify grant winners in November 2024, for project start dates as early as January 2025.

Don't miss our Research Awards.

FEATURED GRANTEE

January 01, 2021 - January 31, 2023

Private Equity Acquisitions of Physician Medical Practices and Implications for Practice Patterns and Costs of Care

Jane Zhu, Oregon Health and Science University

No grantees match these filters, please select a different filter.

January 01, 2024 - December 31, 2024

Evaluating the Effectiveness of the Hospital Price Transparency Rule in Price Reduction

John X Jiang, Michigan State University

New Uses of Existing Drugs: The Effects of FDA Regulation and Off-Label Drug Use on Incentives for Pharmaceutical Innovation

Jennifer Kao, University of California, Los Angeles

January 01, 2024 - December 30, 2024

Market, Organizational, and Policy Drivers of Hospital Price Markups for Specialty Drugs

James Robinson, University of California, Berkeley

How Does Interchangeability Impact Biosimilar Adoption?

Pragya Kakani, Weill Cornell Medicine & Luca Maini, Harvard Medical School

June 01, 2024 - August 31, 2025

Private Equity’s Effects on Primary Care Practices Participating in Medicare Advantage

Jane Zhu, Oregon Health & Science University

Spillover Effects of Private Equity Acquisitions of Physician Practices on Local Market Competitors: Implications for Access to Care

Yashaswini Singh, Brown University

A Double-Edged Sword: Evaluating the Role of Telehealth Expansion and Contraction in the US Opioid Crisis

Niam Yaraghi, University of Miami/Brookings Institution

The Effect of AI-Enabled Clinical Software on Health Care Spending and Health Outcomes

Anna Zink, University of Chicago & Hannah Neprash, University of Minnesota

Impact of Capitation Payment Models on Kidney Health Outcomes

Sri Lekha Tummalapalli, Weill Cornell

February 01, 2023 - June 30, 2024

Evaluating Automatic Enrollment into Marketplace Coverage During the Unwinding of the Medicaid Continuous Coverage Policy: a Two-State Study

Adrianna McIntyre, Harvard University

January 01, 2023 - December 31, 2023

In the Shadows of Trauma: The Economic and Clinical Impact of Childhood Firearm Injuries on Survivors and Family Members

Zirui Song, Harvard Medical School and Massachusetts General Hospital

January 20, 2023 - January 19, 2024

Do Hospital Partnerships with Community-Based Organizations that Address Social Determinants of Health Reduce Hospital Readmission and Mortality?

Yunyu Xiao, Weill Cornell Medicine, Department of Population Health Sciences

March 01, 2023 - August 31, 2024

A State-wide Study of Childbirth-Related Opioid Exposure and Conversion to Postpartum High-Risk Opioid Use

Meredith Matone, University of Pennsylvania and Children’s Hospital of Philadelphia

January 01, 2023 - March 01, 2024

Debunking the Myth that High Drug Prices Accelerate Innovation

Avik Roy, Foundation for Research on Equal Opportunity (FREOPP)

January 01, 2023 - February 29, 2024

Increasing Private Equity Investment in Cancer Care: What is the Effect on Prices and Quality of Care?

Ola Abdelhadi, University of California, Berkeley

January 01, 2023 - June 30, 2023

Can Improving Pharmaceutical Patent Quality Promote Competition and Reduce Drug Prices?

Bhaven N. Sampat, Arizona State University (formerly Columbia University)

January 01, 2023 - June 30, 2024

Increasing Access to Postpartum Mental Health Care via Telehealth: Evidence from Medicaid Coverage of Mental Health Services in Massachusetts

Chanup Jeung, University at Albany, State University of New York (formerly at University of Massachusetts, Amherst)

Understanding Racial and Ethnic Disparities in Timeliness of Diabetes Care

Dan Ly, University of California, Los Angeles & VA Greater Los Angeles

January 01, 2023 - December 31, 2024

The Effect of Hospital Ransomware Attacks on Health Care Delivery and Patient Outcomes

Hannah Neprash, University of Minnesota

June 01, 2023 - May 31, 2024

Improving Competitive Drug Markets by Reviewing Patents

S. Sean Tu, West Virginia University College of Law

The Effects of Physicians’ Financial Transfers from Drug Firms on Prescribing of Physician-Administered Cancer Drugs

Colleen Carey, Cornell University

January 01, 2022 - December 31, 2022

Defining the Digital Divide: Implications for Improving Access to Care

Wendy Brunner, Bassett Medical Center

January 01, 2022 - June 30, 2023

Assessing Postpartum Care Among Medicaid Beneficiaries in an Era of Expanded Access and Telehealth Services

Mark Clapp, Massachusetts General Hospital

February 01, 2022 - June 30, 2023

Marginalized/Minoritized Communities, Health Equity and Medicaid Telehealth Policy

Alison Cuellar, George Mason University

January 01, 2022 - July 01, 2024

Redesigning Payment Policy for Physician-Administered Drugs

Keith Marzilli Ericson, Boston University

Delivering Medicaid Mental Health Services and Supports in Schools

Vinu Ilakkuvan, PoP Health, LLC

Can Medical Practices Afford to Increase Efficiency?

Tim McDonald, Pardee RAND Graduate School

Making Primary Care Count: Intended and Unintended Consequences of the Evaluation & Management Payment Change

January 01, 2022 - December 31, 2023

Vertical Integration of Specialty Physician Practices and the Association with Private Equity Acquisition of Short-Term Acute Care Hospitals

James Roberts, Duke University

Provider Price Strategies and Insurer Counter-Strategies for Infused Drugs in Hospital and Independent Sites of Care

Meals on Wheels Services and Healthcare Utilization Among Frail Older Adults Over Time

Sarah Walsh, Eastern Michigan University

Forum on Traumatic Brain Injury

Katherine Bowman, National Academies of Sciences, Engineering, and Medicine

January 01, 2021 - June 30, 2022

Impact of Medicaid Provider Incentives for Postpartum LARC Provision on Postpartum Contraceptive Use

Jessica Cohen, Harvard University

January 01, 2021 - August 31, 2023

Medically Integrated Dispensing in Oncology

Genevieve Kanter, University of Pennsylvania

February 01, 2021 - May 30, 2022

How Did the Pandemic Change Care for Patients with Chronic Conditions?

May 01, 2021 - July 20, 2022

The Causal Effect of High-Quality Physician-Patient Relationships on Healthcare Costs and Outcomes: Differences by Race/Ethnicity and the Effect of Racial/Ethnic Concordance

Tim Brown, University of California, Berkeley

Price and Quality for Ambulatory Surgery: Differences Between Hospital-Based and Freestanding Centers

Jamie Robinson, University of California, Berkeley

March 01, 2021 - February 28, 2022

Nudging Providers to Curtail Dangerous Opioid Prescribing and Improve the Safety of the Health Care Delivery System

Adam Sacarny, Columbia University

January 01, 2021 - August 31, 2022

Provider Market Power and Adverse Selection in Health Insurance Markets: Evidence from the California Benefits Exchange

Nicholas Tilipman, University of Illinois at Chicago

January 01, 2021 - December 31, 2022

Can Conflict of Interest with the Drug Industry Harm Patients?

Aaron Mitchell, Memorial Sloan Kettering Cancer Center

June 01, 2020 - July 31, 2021

Health and Economic Incidence of the COVID-19 Pandemic

Maria Polyakova, Stanford University

June 01, 2020 - December 31, 2022

The Impact of COVID-19 on Health Care Spending and Practice Patterns

Amol Navathe, University of Pennsylvania

January 01, 2014 - June 30, 2015

The Impact of Payment Reform on Physician Referrals, Patient Flows and Health Care Costs

Bruce Landon, Harvard University

January 01, 2014 - March 15, 2015

Assessing the Impact of Integrated Case Management on Health Services Use and Costs in Medicaid

Gloria Bazzoli, Virginia Commonwealth University

January 01, 2014 - March 31, 2015

Variations in Patient Experience with Tiered Physician Networks

Anna Sinaiko, Harvard University

January 01, 2014 - December 31, 2014

Identifying Winners and Losers Under Proposals to Simplify Drug Plan Choice in Medicare Part D

Jonathan Ketcham, Arizona State University

January 01, 2013 - January 15, 2014

Hospital Acquisition of Physician Practices and Health Care Delivery and Costs

Laurence Baker, Stanford University

January 01, 2013 - October 31, 2013

Evaluating Coverage, Utilization and Access to Care in Medicaid “Early Expander” States Under the Affordable Care Act

Ben Sommers, Harvard University

February 01, 2015 - January 31, 2016

Physician Practice Organization and Health Care Delivery and Costs

January 12, 2015 - January 11, 2016

Do Higher Priced Providers Deliver Higher Quality Care? An Analysis of the Price/Quality Relationship Using HCCI Data

Zack Cooper, Yale University

January 01, 2015 - June 30, 2016

How Are Physician Referral Networks Affected by Physician Practice Ownership and Limited Coverage Network Insurance Products?

January 01, 2015 - April 30, 2016

Physician Practice Styles and Overuse of Healthcare Services

Allison Lipitz-Snyderman, Memorial Sloan Kettering Cancer Center

February 01, 2016 - July 31, 2017

Evaluation of Affordable Care Act Policies to Encourage Accurate Prices for Medicare Services

Miriam Laugesen, Columbia University

January 01, 2016 - October 31, 2017

How Do Patients Rate Experiences with Physicians Who Provide More Low-Value Services?

Prachi Sanghavi, The University of Chicago

January 01, 2016 - December 31, 2016

An Empirical Investigation of Potential Manipulation in the Nursing Home Rating System

Niam Yaraghi, The Brookings Institution

Improving the Effectiveness and Efficiency of High-Risk Care Management through Machine Learning

Ziad Obermeyer, Brigham and Women's Hospital

January 01, 2016 - March 31, 2018

The Prescription Opioid Epidemic: Understanding Its Complications and the Effectiveness of State Policies

Stephen Patrick, Vanderbilt University Medical Center

May 01, 2016 - April 30, 2017

Physician-Driven Overuse of Services for Patients with Advanced Cancer

January 01, 2017 - December 31, 2018

Consumer Directed Health Plan Impact on Low-Value Service Utilization and Spending

Neeraj Sood, University of Southern California

January 01, 2017 - August 31, 2018

eQuality: Improving LGBT, GNC, and DSD Health Through a Comprehensive Medical School Training Program

Susan Sawning, University of Louisville School of Medicine

Patterns and Determinants of Inappropriate Diagnostic Imaging

Gary Young, Northeastern University

Evaluating and Improving Post-Hospitalization Mental Health Follow-Up Care

Kimberley Geissler, University of Massachusetts Amherst

September 01, 2016 - December 31, 2017

Selected Market Failures in Health Care: Analyzing the Scope, Causes, and Potential Solutions

January 01, 2017 - December 31, 2017

Promoting Better Pain Management Outcomes: Precision Decision Support for Opioid Prescription

Ritu Agarwal, University of Maryland

March 01, 2018 - February 28, 2019

Measuring Systemic Overuse in the Privately Insured

Jodi Segal, Johns Hopkins University

January 01, 2018 - June 30, 2019

The Effects of Expanded Access to LARCs on Women’s Outcomes

Jason Lindo, Texas A&M University

January 01, 2018 - March 31, 2019

Addressing Modifiable Healthcare Spending Through Dynamic Modeling Approaches

Julie Lauffenburger, Brigham & Women’s Hospital

January 01, 2018 - December 31, 2019

The Effects of Physician-Hospital Integration on Health Care Spending and Use

Anne Royalty, Indiana University

January 01, 2018 - January 01, 2020

The Impact of Reference Pricing on Hospital-Insurer Bargaining

Christopher Whaley, RAND Corporation

January 01, 2018 - December 31, 2018

Policy Approaches to Insure High Risks

January 01, 2019 - December 31, 2019

Valuing a Cure: Evaluating Different Approaches to Determine a Value-Based Price for a Potential Cure

Principal Investigator: Steven D. Pearson, Institute for Clinical and Economic Review

Very High and Low Residual Spenders in Private Health Insurance Markets

Tom McGuire, Harvard University

January 01, 2019 - September 30, 2020

Persuasion and Welfare in Physician-Industry Relations: Evidence from the Medical Device Industry

Matthew Grennan (currently at UC Berkeley), Wharton School, University of Pennsylvania

January 01, 2019 - March 31, 2021

Effects of Tiered Physician Networks on Health Care Use and Provider Behavior

The Impact of Hospital Consolidation on Care Access, Quality, and Disparities for Low-Income Populations: Evidence from New York Medicaid

Sunita Desai, New York University

January 01, 2019 - December 31, 2024

Why Does the US Overinvest in Technology? The Curious Case of MRI Scanners

January 01, 2019 - March 31, 2022

Impact of ACA Medicaid Expansions on Prenatal Care Utilization and Birth Outcomes

Bassam Dahman, Virginia Commonwealth University

March 01, 2020 - November 30, 2020

Nothing Matters: The Zero-Price Effect in the Individual Insurance Market

Coleman D. Drake, University of Pittsburgh

January 01, 2020 - June 30, 2022

Competitive Dynamics of Physician Referrals in the Era of ACOs

Principal Investigator: Russell J. Funk, University of Minnesota

January 01, 2020 - January 31, 2021

The Impact of Consolidation on Prescription Drug Pricing and Access

Principal Investigator: Josh Feng, University of Utah

June 01, 2020 - August 31, 2022

Geographic Variation in Medicare and Commercial Spending

Principal Investigator: Pierre Thomas Léger, University of Illinois at Chicago

January 06, 2020 - July 31, 2021

Variation Across Health Systems in the Overuse of Healthcare Resources by Older Adults in the United States

Jodi B. Segal, Johns Hopkins University

January 01, 2020 - April 30, 2021

Measuring the Value of Emergency Mental Health Care

Sarah Axeen, University of Southern California

January 01, 2020 - September 30, 2020

Policy Changes that Need to be Made for FQHCs to Utilize Telehealth to Address the Opioid Crisis

Mei Kwong, Center for Connected Health Policy

Improving Postpartum Health through Increased Medicaid Coverage after Childbirth

Maria Steenland, Brown University

January 01, 2020 - July 31, 2022

Bargaining and International Reference Pricing in the Pharmaceutical Industry

Ashvin Gandhi, University of California, Los Angeles

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Research Grants (R series)

Research grants make up the largest category of funding and support by the NIDCD. These grants may be awarded to universities, medical and other health professional schools, colleges, hospitals, research institutes, for-profit organizations, and government institutions that sponsor and conduct biomedical research and development. Research grants may provide funds for salaries, equipment, supplies, travel, and other allowable direct costs of the research as well as for indirect costs to the sponsoring institution or organization.

On this page:

Research project grant (r01), stephen i. katz early stage investigator research project grant (r01), nidcd research opportunities for new investigators to promote workforce diversity (r01 - clinical trial optional), nih research enhancement award (r15).

• Exploratory/Developmental Research Grant Award (R21)

Early Career Research (ECR) Award (R21)

Investigator-initiated Research Project Grants (R01) make up the largest single category of support provided by the NIDCD and by the NIH. The R01 is considered the traditional grant mechanism. These grants are awarded to organizations on behalf of an individual (a principal investigator, or PI) to facilitate pursuit of a research objective in the area of the investigator's research interests and competence.

• NIH Research Project Grants (R01) at grants.nih.gov

The Stephen I. Katz Early Stage Investigator Research Project Grant supports an innovative project in an area of science that represents a change in research direction for an early stage investigator (ESI) and for which no preliminary data exist.

• Stephen I. Katz Early Stage Investigator Research Project Grant (Parent R01) at grants.nih.gov

This program supports early stage and new investigators from diverse backgrounds, including those from groups underrepresented in the health-related sciences. Staff contact for questions about this program: Kelly King, Au.D., Ph.D.

• NIDCD Research Opportunities for New Investigators to Promote Workforce Diversity (R01 - Clinical Trial Optional) at grants.nih.gov

The NIH Research Enhancement Award (R15) program supports small-scale research projects at educational institutions that provide baccalaureate or advanced degrees for a significant number of the nation’s research scientists but that have not been major recipients of NIH support. The goals of the R15 are to support meritorious research, expose students to research, and strengthen the institution’s research environment.

This program replaces the NIH Academic Research Enhancement Award (AREA) Parent Announcement , which expired on January 7, 2019, and will not be reissued. The R15 activity code now includes two programs:

• Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15 - Clinical Trial Not Allowed) at grants.nih.gov
• Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15 - Clinical Trial Required) at grants.nih.gov
• Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 - Clinical Trial Not Allowed) at grants.nih.gov
• Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 - Clinical Trial Required) at grants.nih.gov

For more information, see:

• Notice: Changes to the NIH Academic Research Enhancement Award (AREA)/R15 Program
• NIH Research Enhancement Award (R15) page  – NIH Office of Extramural Research

Please contact the NIDCD’s R15 program coordinator, Susan Sullivan, Ph.D ., with any questions about this program.

Exploratory/Developmental Research Grant Program (R21)

The Exploratory/Developmental Grant (R21) program is intended to encourage exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.

• NIH Exploratory/Developmental Research Grant Program (R21) at grants.nih.gov

The NIDCD Early Career Research (ECR) R21 Award supports both basic and clinical research from scientists who are beginning to establish an independent research career. It cannot be used for thesis or dissertation research. The research must be focused on one or more of the areas within the biomedical and behavioral scientific mission of the NIDCD: hearing, balance, taste, smell, voice, speech, or language.

The NIDCD ECR Award R21 grant mechanism supports different types of projects including secondary analysis of existing data; small, self-contained research projects; development of research methodology; translational research; outcomes research; and development of new research technology. Irrespective of the type of project, the intent of the NIDCD ECR Award R21 is for the program director(s)/principal investigator(s) (PD(s)/PI(s)) to obtain sufficient preliminary data for a subsequent R01 application.

Staff contact for questions on the NIDCD ECR R21 Award:

Bracie Watson, Ph.D. National Institute on Deafness and Other Communication Disorders (NIDCD) (301) 402-3458

• NIDCD Early Career Research (ECR) Award (R21) at grants.nih.gov

Transforming the understanding and treatment of mental illnesses.

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Opportunities & announcements, funding strategy for grants, grant writing & approval process, managing grants, clinical research, small business research.

The National Institute of Mental Health (NIMH) is the largest funder of research on mental disorders in the world. Below you can find NIMH funding opportunities and announcements, including those specific to clinical research and training. Also, learn more about NIMH funding strategies, the application process, and grants management.

  Notify the NIMH Press Team about NIMH-funded research that has been submitted to a journal for publication, and we may be able to promote the findings.

Research and Training Opportunities

New section.

Looking for ways to enrich your medical school experience? Check out our directories of clinical, research, and public health opportunities.

Looking for ways to enrich your medical school experience? Search for fellowships, internships, summer programs, scholarships, and grants currently available in the United States and abroad.

Earn two degrees in four to five years to improve the health of the individuals and communities you serve.

The National Institutes of Health (NIH) Medical Research Scholars Program (MRSP) is a comprehensive, year-long research enrichment program designed to attract the most creative, research-oriented medical, dental, and veterinary students to the intramural campus of the NIH in Bethesda, MD.

Summer programs at the National Institutes of Health (NIH) provide an opportunity to spend a summer working at the NIH side-by-side with some of the leading scientists in the world, in an environment devoted exclusively to biomedical research.

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A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

• Extramural Programs
• Funding Opportunities
• Performance Data
• Research and Training Highlights
• News and Notices

Research Grant Funding

• NIOSH funds four types of research grants (R01, R03, R21, and K01).
• Applications are accepted three times per year.
• Researchers are encouraged to develop proposed research around NIOSH's priority goals.

NIOSH funds many types of research. This includes:

• Identification and investigation of the relationships between hazardous working conditions and associated occupational diseases and injuries;
• Development of more sensitive means of evaluating hazards at work sites;
• Development of methods for measuring early markers of adverse health effects and injuries;
• Development of new protective equipment and engineering control technology to reduce work-related illnesses and injuries;
• Development of work practices that reduce the risks of occupational hazards; and
• Evaluation of the technical feasibility or application of a new or improved occupational safety and health procedure, method, technique, or system.

Funding by category

Large osh research grants (r01).

The purpose of RO1 research grants is to

• Develop an understanding of the risks and conditions that are associated with occupational diseases and injuries.
• Explore methods for reducing risks and for preventing or minimizing exposure to hazardous conditions in the workplace.
• Translate significant scientific findings into prevention practices and products that will effectively reduce work-related illnesses and injuries.

Small Research Grants (R03)

R03 grants support small research projects that can be carried out in a short period of time with limited resources. Potential projects include:

• Pilot and feasibility studies
• Secondary analysis of existing data
• Small, self-contained research projects
• Development of research methodology; and
• Development of new research technology

Exploratory Grant Program (R21)

R21 grants are intended to encourage new exploratory and developmental research projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area. They may also lead to the development of novel techniques, agents, methodologies, models, or applications. These innovations could have a major impact on a field of biomedical, behavioral, or clinical research.

Applications for R21 awards should describe projects distinct from those supported through the traditional R01 mechanism. Projects of limited cost or scope that use widely accepted approaches and methods within well-established fields are better suited for the R03 small grant mechanism.

Mentored Research Scientist Career Development (K01)

KO1 grants are intended to prepare the next generation of occupational safety and health researchers and educators. Emphasis for funding is placed on projects that specifically address the priority goals of NIOSH Strategic Plan . Research training supported by this announcement may include a wide range of training modalities reflecting the diverse approaches needed to effectively address occupational safety and health problems effectively.

Ongoing funding opportunities

The announcements listed below are published in the NIH Guide to Grants and Contracts. Each announcement specifies the research priorities, type of grant activity supported, and information needed to submit a grant application. Applications are accepted three times a year on standard due dates .

Occupational Safety and Health Research (RO1)

NIOSH Small Research Grant Program (R03)

NIOSH Exploratory and/or Developmental Grant Program (R21)

Mentored Research Scientist Development Award (K01)

Previous funding opportunities

These funding announcements have expired and been reissued. The links are included here as a reference.

Previous announcements

Occupational Safety and Health Research (RO1) - Active 2013-2018

NIOSH Small Research Grant Program (R03) - Active 2012-2018

NIOSH Exploratory and/or Developmental Grant Program (R21) - Active 2012-2018

Mentored Research Scientist Development Award (K01) - Active 2012-2018

NIOSH has identified research priorities in its strategic plan . NIOSH Sector and Cross-Sector programs have identified priority goals for extramural research to fill important research gaps. These are issues that NIOSH intramural (i.e., internal) projects are not addressing. Researchers should consider developing their research concept around one or more priority goals. Researchers are also encouraged to identify priority goals for extramural research as a part of their application.

Resource‎

Funding data.

Learn more about:

• Success rates for research grants
• Current funding levels for research grants and other awards
• Repository of all active awards

National Institute for Occupational Safety and Health (NIOSH)

The Occupational Safety and Health Act of 1970 established NIOSH as a research agency focused on the study of worker safety and health, and empowering employers and workers to create safe and healthy workplaces.

NIOSH Extramural Research and Training

HHS halts grants for nonprofit EcoHealth that funded gain-of-function research in Wuhan

T he Department of Health and Human Services suspended all federal grants Tuesday to the controversial Manhattan nonprofit EcoHealth Alliance, which funded gain-of-function virus research in Wuhan, China in advance of the COVID-19 pandemic.

HHS deputy assistant secretary for acquisitions Katrina Brisbon informed EcoHealth President Dr. Peter Daszak in a Wednesday letter released by a House subcommittee investigating the outbreak that there was “adequate evidence” to recommend the nonprofit be cut off from future government contracts, writing “immediate action is necessary to protect the public interest.”

“Debarment is generally for a period not to exceed three years; however, regardless of whether EHA contests this action or responds to this Notice, I may impose debarment for a longer period or shorter period as the circumstances warrant,” Brisbon added.

In an accompanying memo, Brisbon said that EcoHealth had been “more than two years late” with one of its reviews of a grant proposal for its Wuhan project, which had for a time operated around a government-wide moratorium on the practice .

The National Institutes of Health (NIH), which permitted the grant, gave EcoHealth several opportunities to disprove that its experiments constituted gain-of-function research — but the group “failed to do so,” according to Brisbon.

That research also “likely violated protocols of the NIH regarding biosafety,” she added, with experiments conducted at biosafety level 2 — which according to Rutgers University molecular biologist Dr. Richard Ebright is comparable to the standards of safety at a typical dentist’s office .

Alarmingly, Brisbon revealed that NIH has yet to receive several materials from EcoHealth about its novel bat coronavirus research at the now-notorious Wuhan Institute of Virology (WIV) or from the Chinese lab itself.

Daszak, in sworn congressional testimony earlier this month, said he had not even asked Wuhan researchers — including longtime collaborator and WIV deputy director Shi Zhengli — for viral sequences since before the pandemic began.

Brisbon’s memo also referenced an internal probe of “allegations that WIV released the coronavirus that was responsible for the COVID-19 global pandemic,” though no EcoHealth or other US-funded grant has been tied yet to the outbreak.

“EcoHealth Alliance is disappointed by HHS’ decision today and we will be contesting the proposed debarment,” a spokesperson said in a statement. “We disagree strongly with the decision and will present evidence to refute each of these allegations and to show that NIH’s continued support of EcoHealth Alliance is in the public interest.”

“EcoHealth Alliance provably defrauded the US government, provably breached contractual terns of US-government grants, and, through the reckless gain-of-function research it conducted in Wuhan, probably caused the COVID-19 pandemic, killing 20 million and costing $25 trillion,” Ebright told The Post.

“Nevertheless, EcoHealth Alliance was awarded more than $50 million in new US-government funding since the start of the pandemic with most of that funding earmarked for the same kinds of reckless virus discovery and virus enhancement research that likely caused pandemic.”

The memo attached to the letter notes EcoHealth received a grant of more than $4 million from the NIH titled “Understanding the Risk of Bat Coronavirus Emergence.”

More than half a million dollars of that funding flowed to the WIV between 2014 and 2021, a Government Accountability Office report found last year, to conduct “genetic experiments to combine naturally occurring bat coronaviruses with SARS and MERS viruses, resulting in hybridized (also known as chimeric) coronavirus strains.”

The grant was initially suspended in April 2020, with NIH’s then-principal deputy director Lawrence Tabak revealing in October 2021 that EcoHealth had violated the terms of its grant by performing the gain-of-function research.

The project had modified novel bat coronaviruses and made them 10,000 times more infectious for research on lab mice — but EcoHealth “failed to report” that to NIH.

Tabak stressed that the bat coronaviruses studied on the taxpayers’ dime in Wuhan could not have caused the COVID-19 pandemic because the “sequences of the viruses are genetically very distant.”

But other EcoHealth grant proposals have since come under scrutiny from experts like Ebright, who said “the evidence provided by the genome sequence” from another 2018 grant proposal project submitted to US Defense Advanced Research Projects Agency was a “ smoking gun .”

Appearing before the House Select Subcommittee on the Coronavirus Pandemic on May 1, Daszak repeatedly denied that his group helped fund the gain-of-function experiments.

“EcoHealth Alliance and Dr. Peter Daszak should never again receive a single penny from the US taxpayer,” said COVID subcommittee chairman Brad Wenstrup (R-Ohio), who had recommended a criminal investigation of Daszak before the hearing.

“Only two weeks after the Select Subcommittee released an extensive report detailing EcoHealth’s wrongdoing and recommending the formal debarment of EcoHealth and its president, HHS has begun efforts to cut off all US funding to this corrupt organization,” Wenstrup added.

“EcoHealth facilitated gain-of-function research in Wuhan, China without proper oversight, willingly violated multiple requirements of its multimillion-dollar National Institutes of Health grant, and apparently made false statements to the NIH,” he went on.

“EcoHealth’s immediate funding suspension and future debarment is not only a victory for the US taxpayer, but also for American national security and the safety of citizens worldwide.”

The HHS letter to Daszak also drew attention to other NIH grants it received to study viruses in Bangladesh, Myanmar, Laos, Vietnam and other Southeast Asian nations, all of which are “uniquely focused on either emerging infectious disease, highly transmissible pathogens, or novel viruses.”

The Wuhan Institute of Virology was barred for 10 years from receiving any HHS grants in July 2023, months after both the FBI and US Energy Department determined a lab leak was the most likely cause of the COVID pandemic.

Wenstrup in his statement added that his subcommittee’s “investigation into EcoHealth and the origins of COVID-19 is far from over,” with high-profile public hearings planned in the coming weeks to question Tabak and former National Institute of Allergy and Infectious Diseases Director Dr. Anthony Fauci.

“There must be full accountability, both civil and criminal, for EcoHealth and EcoHealth’s officers — particularly its president, Peter Daszak,” Ebright declared.

“And there must be full accountability for the US-government officials who enabled, abetted, and covered up EcoHealth’s misdeeds and who obstructed investigation of EcoHealth’s misdeeds.”

EDITOR’S NOTE: An earlier version of this story incorrectly stated that EcoHealth Alliance was restricted from receiving HHS grants for 10 years in July 2023. In fact, the Wuhan Institute of Virology was barred from access to the grants.

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Opportunities for the Development of Tyumen Oblast Based on Innovations for the Oil and Gas Sector, Production of High-Tech Equipment, and High-Tech Services

• REGIONAL STUDIES
• Published: 07 April 2024
• Volume 14 , pages 77–85, ( 2024 )

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• V. A. Kryukov 1 &
• A. N. Tokarev 1  

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Currently, the main strategic drivers of regional development often include innovation and diversification. Activities that lie at the intersection of these directions or combine them, i.e., in essence, innovation-based diversification, appear promising. For the resource sector of the economy and raw materials regions, such diversification means the development of knowledge-intensive suppliers and high-tech services, including within specialized clusters. In the context of the increasing complexity of the resource base of the oil and gas sector and pressure from sanctions, these problems are becoming increasingly urgent for Russia. A useful example is the formation of a competitive oil industry cluster in southern Tyumen oblast. The article shows that a cluster can become an important factor in the socioeconomic development of the region. At the same time, the long-term contribution of R&D to the economic growth of the region can only be ensured with a significant share of innovative projects (knowledge-intensive, with high added value) that respond to all new challenges associated with changes in the main assets of the Western Siberian oil and gas sector—the resource base.

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The article was prepared according to the research plan of the Institute of Economics and Industrial Engineering, Siberian Branch, Russian Academy of Sciences, project “Resource Territories of Eastern Russia and the Arctic Zone: Features of the Processes of Interaction and Ensuring the Connectivity of Regional Economies in the Context of Modern Scientific, Technological, and Social Challenges,” no. 121040100278-8.

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Kryukov, V.A., Tokarev, A.N. Opportunities for the Development of Tyumen Oblast Based on Innovations for the Oil and Gas Sector, Production of High-Tech Equipment, and High-Tech Services. Reg. Res. Russ. 14 , 77–85 (2024). https://doi.org/10.1134/S2079970523600373

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Received : 17 February 2023

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Published : 07 April 2024

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DOI : https://doi.org/10.1134/S2079970523600373

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The bourgeois charm of Siberia's oil capital

If you’re driving west across Russia from the Pacific Ocean, the first thing that you notice upon entering the city of Tyumen is the McDonalds. Tyumen has long been one of the only Siberian cities with a McDonalds restaurant. Although the fast-food giant has plans to open locations in nearby Novosibirsk and other regional cities, Siberia still contains one of the longest distances on earth outside of Africa where you can remain on a major highway and not see a McDonalds. Until you reach Tyumen, that is.

A stop in Tyumen provides an interesting glimpse into how modern Russia’s oil revenue has influenced Siberia’s oldest Russian city. Tyumen is a great stopover point on the Trans-Siberian Railroad and a short ride from Yekaterinburg (five hours) or Tobolsk (four hours).

In the 16th century, Russia started expanding eastward into parts of Central Asia ruled by the Tatars, an Islamic people who still live thoughout Russia. A band of Cossacks wrested control of Tyumen from the Tatars in 1580. Six years later, Russians established a fort in Tyumen on the Tura River.

For centuries, Tyumen vied with the nearby city of Tobolsk—once the official capital of Siberia—for the prestige of the region’s most important city. Tyumen won in the end, when the Trans-Siberian Railroad bypassed Tobolsk and was routed through this now oil-rich city.

Tyumen played an important role in Russian history during times of war. At the beginning of the Russian Civil War, the Bolshevik Red Army slowly pushed the White Army, commanded by Admiral Alexander Kolchak, into Siberia. Kolchak and his anti-Bolshevik forces holed up in Tyumen until the Red Army overtook them in January of 1918.

During the Second World War, many Russian industries were moved away from the front to Siberian cities. Tyumen had already become an industrial capital during the early Soviet era, and the city became an ideal spot to relocate Russia’s western factories. As Nazi forces approached Russia in 1941, the embalmed body of Vladimir Lenin was sent from the Lenin Mausoleum in Moscow’s Red Square by train to the Tyumen State Agricultural Academy for safekeeping. In 1945, Lenin’s body was shipped back to Moscow.

Some of the factories relocated to Tyumen during wartime remained in the city. The discovery of oil in the region catapulted Siberia’s oldest Russian settlement to further prosperity. Modern Tyumen is a vibrant city with a number of universities and a revamped center well-suited for exploration by foot.

Start your walking tour around central Tyumen on Ulitsa Respubliki. The city’s main drag has fine pedestrian walkways and leads wanderers past an impressive collection of tsarist-era buildings that recall Tyumen’s importance in the beginning of Russia’s colonization of Siberia.

From the southeastern end of Ul. Respubliki, head north toward the Tura River and take a brief side trip onto Ul. Ordzhonikidze to visit the Fine Arts Museum (47 Ul. Ordzhonikidze) which houses exhibits of classical Russian and Soviet art as well as traditional bone carving and works produced by the native people who live in the far north of Tyumen Oblast.

Back on Ul. Respubliki, you’ll soon see the city’s requisite Lenin statue by the local government buildings. A block away, opposite Lenin, is Tyumen’s city park, a delightful place to walk or hop on one of its amusement rides.

Most Siberian cities developed under the watchful eyes of the atheist Soviet regime and churches are usually not Siberia’s strongpoint. But this isn’t true in four-centuries-old Tyumen. Strolling up Ul. Respubliki, you’ll soon come to the Church of the Saviour (41 Ul. Lenina) and the Znamensky Cathedral (13 Ul. Semakova). Each of these stunning Baroque-influenced churches are located right off Ul. Respubliki and were built in the late 18th century.

Tyumen is also famous for its historic wooden houses. Heading further up Ul. Respubliki, stop to wander around some of the side streets and snap photos of these ornate wooden structures which provide a glimpse back in time. Near the Tura River, you’ll pass a civil war monument in remembrance of the Tyumen natives who died fighting the White Army and the Tyumen State Agricultural Academy (7 Ul. Respubliki) an impressive building in its own right where Lenin was stored during the Second World War.

Near the end of Ul. Respubliki, take a walk over the Tura River on the Lover’s Bridge, a suspension bridge open to foot traffic only that has become one of Tyumen’s iconic sights. The other side of the river is a great place to see more of Tyumen’s signature wooden houses as well as take in the churches scattered around the city center.

Save the best for last and visit the Trinity Monastery (10 Ul. Kommunisticheskaya) at the end of Ul. Respubliki. A white wall surrounds the monastery, giving it the appearance of a mini-kremlin, and the golden onion domes of the 18th century churches within should not be missed.

Although navigating Tyumen is straightforward enough, the St. Petersburg-based travel company OSTWEST can arrange a city tour in Tyumen and the surrounding countryside.

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