Protein Data Bank: From Two Epidemics to the Global Pandemic to mRNA Vaccines and Paxlovid
Genetic mutation and biological pathway prediction from whole slide images using deep learning
COMMENTS
A quantitative and qualitative analysis of the COVID-19 pandemic model
Although, there is a variety of modeling approaches that have been proposed so far for prediction and evaluation of the COVID-19 disease, there are more questions that can still be answered. There are some related works that sensitivity analysis used in their studies [13,17]. They used this technique only for special variables and parameters.
11 Questions to Ask About COVID-19 Research
When hundreds of millions of people are vaccinated, millions of them will be afflicted anyway, in the course of life, by conditions like strokes, anaphylaxis, and Bell's palsy. "We have to have faith that people collecting the data will let us know if we are seeing those things above the baseline rate.". 3.
SARS-CoV-2 and COVID-19: The most important research questions
The sixth question concerns how COVID-19 should be treated and what treatment options should be made available. COVID-19 is a self-limiting disease in more than 80% of patients. Severe pneumonia occurred in about 15% of cases as revealed in studies with large cohorts of patients. The gross case fatality is 3.4% worldwide as of February 25, 2020.
Research on Quantitative Analysis of Multiple Factors Affecting COVID
From the data of the selected 44 countries, it can be seen that population factors and flight factors have a greater impact on the spread of COVID-19. Every 1% increase in population factors will increase the spread of the epidemic by 1.044%. Every 1% increase in the number of arrival flights will increase the spread of the epidemic by 0.98%.
PDF COVID-19 Key Research Questions and Recommendations
COVID-19 CLINICAL TRIAL RECOMMENDATIONS. -As multiple federal research agencies have demonstrated, it is most ethical and prudent to enroll patients with COVID-19 in clinical trials rather than use clinically unproven therapies. There are multiple ongoing trials, some with adaptive designs, which potentially can quickly answer pressing ...
Coronavirus disease (COVID-19) pandemic: an overview of systematic
The spread of the "Severe Acute Respiratory Coronavirus 2" (SARS-CoV-2), the causal agent of COVID-19, was characterized as a pandemic by the World Health Organization (WHO) in March 2020 and has triggered an international public health emergency [].The numbers of confirmed cases and deaths due to COVID-19 are rapidly escalating, counting in millions [], causing massive economic strain ...
SARS-CoV-2 and COVID-19: The most important research questions
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing global health emergency. Here we highlight nine most important research questions concerning virus transmission, asymptomatic and presymptomatic virus shedding, diagnosis, treatment, vaccine development, origin of virus and viral pathogenesis.
COVID-19 impact on research, lessons learned from COVID-19 research
The impact on research in progress prior to COVID-19 was rapid, dramatic, and no doubt will be long term. The pandemic curtailed most academic, industry, and government basic science and clinical ...
Methodological quality of COVID-19 clinical research
We performed a systematic review to evaluate the methodological quality of currently available COVID-19 studies compared to historical controls. A total of 9895 titles and abstracts were screened ...
The effect of the definition of 'pandemic' on quantitative ...
Travel rates. One important question about pandemic risk is what effect inter-regional travel rates have on the probability of a pandemic occurring 16,17,46,47.Here we model epidemics occurring in ...
A quantitative and qualitative analysis of the COVID-19 ...
This is an infectious disease and can be modeled as a system of non-linear differential equations with reaction rates. This work reviews and develops some suggested models for the COVID-19 that can address important questions about global health care and suggest important notes. Then, we suggest an updated model that includes a system of ...
Key ethical questions for research during the COVID-19 pandemic
In these times of rapid change, with high levels of uncertainty, anxiety, social isolation, and financial pressure, mental health worldwide is likely to be at risk. Researchers are rightly ensuring that mental health research is included in the response to the coronavirus disease 2019 (COVID-19) pandemic.1 Here, we reflect on ethical issues to consider when conducting research on self-harm ...
Quantitative analysis of the impact of COVID-19 on the ...
Aim: The coronavirus disease 2019 (COVID-19) pandemic has imposed a heavy burden on emergency medical services (EMS) systems. Therefore, we quantitatively analyzed impacts of COVID-19 on the EMS system in Tokyo. Methods: In this retrospective observational study, we used publicly available data, including the daily number of newly diagnosed patients with COVID-19, the weekly number of ...
Questions about COVID-19 and your research?
As the ongoing Coronavirus Disease 2019 (COVID-19) outbreak continues to change rapidly, here is information that the Harvard University research community may find helpful. We realize that the COVID-19 outbreak may cause hardship to research, however it is also important to weigh the possible harms to subjects, taking all issues into account.
Impact of the COVID-19 pandemic on mental health and well-being of
Introduction The COVID-19 pandemic has certainly resulted in an increased level of anxiety and fear in communities in terms of disease management and infection spread. Due to fear and social stigma linked with COVID-19, many individuals in the community hide their disease and do not access healthcare facilities in a timely manner. In addition, with the widespread use of social media, rumours ...
8 Major Findings and Research Questions
Major Findings and Research Questions INTRODUCTION. The COVID-19 pandemic, which began in late 2019, created unprecedented global disruption and infused a significant level of uncertainty into the lives of individuals, both personally and professionally, around the world throughout 2020. The significant effect on vulnerable populations, such as ...
Qualitative and quantitative analysis of the COVID-19 pandemic by a two
Qualitative and quantitative analysis of the spread trends and possible measures are extremely important for prevention and control of COVID-19. A reliable epidemiological model, which consists of a set of coupled differential equations, is a strong tool for simulating mechanism of the spreading trend and how to control the spread of the disease.
PDF The Impact of Covid-19 on Student Experiences and Expectations ...
more likely to delay graduation due to COVID-19 and are 41% more likely to report that COVID-19 impacted their major choice. Further, COVID-19 nearly doubled the gap between higher- and lower-income students' expected GPA.4 There also is substantial variation in the pandemic's e ect on preference for online learning,
Questions About COVID-19 and Your Research
Research study personnel should let participants decide if they would like to wear a mask if the study procedures allow it. Researchers may wish to inform their study population of the current COVID-19 status on campus, or in the study location if elsewhere, including level of community transmission of COVID-19 and COVID-19 vaccination coverage ...
Learning about COVID-19: a qualitative interview study of Australians
Quantitative surveys to determine how publics were responding to coverage of the COVID-19 crisis in news and social media have identified an association between COVID-19-related news and social media consumption and heightened anxiety and distress in Russia , China [29, 30] and USA . Malaysian research found that respondents mainly used ...
COVID-19 MCH Research Agenda
A research agenda to understand the short- and long-term mechanisms and impacts of the COVID-19 pandemic on children. Understanding the full impact of the COVID-19 pandemic on US children, families and communities is critical to (1) documenting the scope of the problem, (2) identifying solutions and mitigating harm and (3) building more resilient response systems.
Full article: Royal Society report: what would a comprehensive
Is the report relevant for policymaking? The Royal Society recently published a report entitled 'COVID-19: examining the effectiveness of non-pharmaceutical interventions' whose objective was to 'assess what has been learnt about the effectiveness of the application of non-pharmaceutical interventions (NPIs) during the COVID-19 pandemic of 2020-2023 by assembling and examining evidence ...
The Strategies for Quantitative and Qualitative Remote Data Collection
Background. The COVID-19 pandemic is transforming the landscape of clinical research. The pandemic has necessitated the unexpected adaptation of ongoing clinical research activities to web-based or blended design (ie, part web-based, part in-person) models [] and has rapidly accelerated a shift within clinical research toward web-based study designs.
Effects of the COVID-19 pandemic on individuals with Chemical
Abstract Background: The Center for Disease Control has estimated that over 24 million have been infected with Covid-19 in the US with over 6,700,000 being hospitalized, and over 1,174,000 deaths. Several other industrialized countries show similar numbers (CSSE, 2021). Chemical Intolerance (CI) is characterized by multi-system symptoms initiated by a one-time high dose or persistent low-dose ...
Exploring Dating App Intimacies During COVID-19 in the UK: A Protocol
Anonymized survey results were generated by MEL Research and are being analyzed by the research team using SPSS and R. Data analysis was descriptive and inferential to explore changes in dating app patterns of use across the three time points (before, during and after COVID-19) and how they are linked to different demographic and socio-economic ...
A critical look at online survey or questionnaire-based research
Online survey or questionnaire-based studies collect information from participants responding to the study link using internet-based communication technology (e.g. E-mail, online survey platform). There has been a growing interest among researchers for using internet-based data collection methods during the COVID-19 pandemic, also reflected in ...
US government suspends funding for virus research group at center of
Before Covid-19 emerged, a US government grant to EcoHealth had funded studies into bat coronaviruses at the lab in Wuhan, China. Although US-funded research at the lab has not been linked to the ...
Covid origins in spotlight, as feds cut funding to virus hunters
Covid origins in spotlight, as feds cut funding to virus hunters. By Dan Diamond. with research by McKenzie Beard. May 16, 2024 at 8:04 a.m. EDT. The Washington Post's essential guide to health ...
Carrying Out Rapid Qualitative Research During a Pandemic: Emerging
Qualitative research carried out during the COVID-19 pandemic can ask and answer questions which complement epidemiological data by providing insight into people's lived experiences of disease, care, and epidemic response efforts ( Teti et al., 2020 ). The exacerbation of social, health, and economic inequalities; the implementation of health ...
IMAGES
VIDEO
COMMENTS
Although, there is a variety of modeling approaches that have been proposed so far for prediction and evaluation of the COVID-19 disease, there are more questions that can still be answered. There are some related works that sensitivity analysis used in their studies [13,17]. They used this technique only for special variables and parameters.
When hundreds of millions of people are vaccinated, millions of them will be afflicted anyway, in the course of life, by conditions like strokes, anaphylaxis, and Bell's palsy. "We have to have faith that people collecting the data will let us know if we are seeing those things above the baseline rate.". 3.
The sixth question concerns how COVID-19 should be treated and what treatment options should be made available. COVID-19 is a self-limiting disease in more than 80% of patients. Severe pneumonia occurred in about 15% of cases as revealed in studies with large cohorts of patients. The gross case fatality is 3.4% worldwide as of February 25, 2020.
From the data of the selected 44 countries, it can be seen that population factors and flight factors have a greater impact on the spread of COVID-19. Every 1% increase in population factors will increase the spread of the epidemic by 1.044%. Every 1% increase in the number of arrival flights will increase the spread of the epidemic by 0.98%.
COVID-19 CLINICAL TRIAL RECOMMENDATIONS. -As multiple federal research agencies have demonstrated, it is most ethical and prudent to enroll patients with COVID-19 in clinical trials rather than use clinically unproven therapies. There are multiple ongoing trials, some with adaptive designs, which potentially can quickly answer pressing ...
The spread of the "Severe Acute Respiratory Coronavirus 2" (SARS-CoV-2), the causal agent of COVID-19, was characterized as a pandemic by the World Health Organization (WHO) in March 2020 and has triggered an international public health emergency [].The numbers of confirmed cases and deaths due to COVID-19 are rapidly escalating, counting in millions [], causing massive economic strain ...
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing global health emergency. Here we highlight nine most important research questions concerning virus transmission, asymptomatic and presymptomatic virus shedding, diagnosis, treatment, vaccine development, origin of virus and viral pathogenesis.
The impact on research in progress prior to COVID-19 was rapid, dramatic, and no doubt will be long term. The pandemic curtailed most academic, industry, and government basic science and clinical ...
We performed a systematic review to evaluate the methodological quality of currently available COVID-19 studies compared to historical controls. A total of 9895 titles and abstracts were screened ...
Travel rates. One important question about pandemic risk is what effect inter-regional travel rates have on the probability of a pandemic occurring 16,17,46,47.Here we model epidemics occurring in ...
This is an infectious disease and can be modeled as a system of non-linear differential equations with reaction rates. This work reviews and develops some suggested models for the COVID-19 that can address important questions about global health care and suggest important notes. Then, we suggest an updated model that includes a system of ...
In these times of rapid change, with high levels of uncertainty, anxiety, social isolation, and financial pressure, mental health worldwide is likely to be at risk. Researchers are rightly ensuring that mental health research is included in the response to the coronavirus disease 2019 (COVID-19) pandemic.1 Here, we reflect on ethical issues to consider when conducting research on self-harm ...
Aim: The coronavirus disease 2019 (COVID-19) pandemic has imposed a heavy burden on emergency medical services (EMS) systems. Therefore, we quantitatively analyzed impacts of COVID-19 on the EMS system in Tokyo. Methods: In this retrospective observational study, we used publicly available data, including the daily number of newly diagnosed patients with COVID-19, the weekly number of ...
As the ongoing Coronavirus Disease 2019 (COVID-19) outbreak continues to change rapidly, here is information that the Harvard University research community may find helpful. We realize that the COVID-19 outbreak may cause hardship to research, however it is also important to weigh the possible harms to subjects, taking all issues into account.
Introduction The COVID-19 pandemic has certainly resulted in an increased level of anxiety and fear in communities in terms of disease management and infection spread. Due to fear and social stigma linked with COVID-19, many individuals in the community hide their disease and do not access healthcare facilities in a timely manner. In addition, with the widespread use of social media, rumours ...
Major Findings and Research Questions INTRODUCTION. The COVID-19 pandemic, which began in late 2019, created unprecedented global disruption and infused a significant level of uncertainty into the lives of individuals, both personally and professionally, around the world throughout 2020. The significant effect on vulnerable populations, such as ...
Qualitative and quantitative analysis of the spread trends and possible measures are extremely important for prevention and control of COVID-19. A reliable epidemiological model, which consists of a set of coupled differential equations, is a strong tool for simulating mechanism of the spreading trend and how to control the spread of the disease.
more likely to delay graduation due to COVID-19 and are 41% more likely to report that COVID-19 impacted their major choice. Further, COVID-19 nearly doubled the gap between higher- and lower-income students' expected GPA.4 There also is substantial variation in the pandemic's e ect on preference for online learning,
Research study personnel should let participants decide if they would like to wear a mask if the study procedures allow it. Researchers may wish to inform their study population of the current COVID-19 status on campus, or in the study location if elsewhere, including level of community transmission of COVID-19 and COVID-19 vaccination coverage ...
Quantitative surveys to determine how publics were responding to coverage of the COVID-19 crisis in news and social media have identified an association between COVID-19-related news and social media consumption and heightened anxiety and distress in Russia , China [29, 30] and USA . Malaysian research found that respondents mainly used ...
A research agenda to understand the short- and long-term mechanisms and impacts of the COVID-19 pandemic on children. Understanding the full impact of the COVID-19 pandemic on US children, families and communities is critical to (1) documenting the scope of the problem, (2) identifying solutions and mitigating harm and (3) building more resilient response systems.
Is the report relevant for policymaking? The Royal Society recently published a report entitled 'COVID-19: examining the effectiveness of non-pharmaceutical interventions' whose objective was to 'assess what has been learnt about the effectiveness of the application of non-pharmaceutical interventions (NPIs) during the COVID-19 pandemic of 2020-2023 by assembling and examining evidence ...
Background. The COVID-19 pandemic is transforming the landscape of clinical research. The pandemic has necessitated the unexpected adaptation of ongoing clinical research activities to web-based or blended design (ie, part web-based, part in-person) models [] and has rapidly accelerated a shift within clinical research toward web-based study designs.
Abstract Background: The Center for Disease Control has estimated that over 24 million have been infected with Covid-19 in the US with over 6,700,000 being hospitalized, and over 1,174,000 deaths. Several other industrialized countries show similar numbers (CSSE, 2021). Chemical Intolerance (CI) is characterized by multi-system symptoms initiated by a one-time high dose or persistent low-dose ...
Anonymized survey results were generated by MEL Research and are being analyzed by the research team using SPSS and R. Data analysis was descriptive and inferential to explore changes in dating app patterns of use across the three time points (before, during and after COVID-19) and how they are linked to different demographic and socio-economic ...
Online survey or questionnaire-based studies collect information from participants responding to the study link using internet-based communication technology (e.g. E-mail, online survey platform). There has been a growing interest among researchers for using internet-based data collection methods during the COVID-19 pandemic, also reflected in ...
Before Covid-19 emerged, a US government grant to EcoHealth had funded studies into bat coronaviruses at the lab in Wuhan, China. Although US-funded research at the lab has not been linked to the ...
Covid origins in spotlight, as feds cut funding to virus hunters. By Dan Diamond. with research by McKenzie Beard. May 16, 2024 at 8:04 a.m. EDT. The Washington Post's essential guide to health ...
Qualitative research carried out during the COVID-19 pandemic can ask and answer questions which complement epidemiological data by providing insight into people's lived experiences of disease, care, and epidemic response efforts ( Teti et al., 2020 ). The exacerbation of social, health, and economic inequalities; the implementation of health ...