Biological, Psychological, and Social Determinants of Depression: A
In this paper, we describe and present the vast, fragmented, and complex literature related to this topic. This review may be used to guide practice, public health efforts, policy, and research related to mental health and, specifically, depression. ... This paper discusses key areas in depression research; however, an exhaustive discussion of ...
Anxiety, Depression and Quality of Life—A Systematic Review of Evidence
3.5. Meta-Analyses on Anxiety, Depression and SF Summary Scores . In total, eight studies on adults were included in a supplementary meta-analyses of several research questions on SF PCS and MCS in association with anxiety and depressive disorders. Forest plots for the analyses are provided in the supplementary materials (Figures S1-S10).
The neuroscience of depressive disorders: A brief review of the past
In this essay, we have briefly reviewed a selected range of key discoveries that neuroscientific research has made on the topic of depressive disorders in the last decades. We have shown that depression has been linked to a wide range of abnormalities on different levels of neuroscientific description ranging from molecules and cells to brain ...
The serotonin theory of depression: a systematic umbrella ...
The idea that depression is the result of abnormalities in brain chemicals, particularly serotonin (5-hydroxytryptamine or 5-HT), has been influential for decades, and provides an important ...
(PDF) Explanations of Depression: Theoretical and ...
Running Head: Explanations of Depression. Abstract. The current paper critically evaluates Beck and Bredemeier's (2016) Unified Model of. Depression (UMD) and explores some of the wider issues ...
Evolution and Emerging Trends in Depression Research From 2004 to 2019
Econometric analysis of the relationship between vitamin D deficiency and depression was performed by Yunzhi et al. and Shauni et al. performed a bibliometric analysis of domestic and international research papers on depression-related genes from 2003 to 2007. A previous review of depression-related bibliometric studies revealed that there is ...
Psychological treatment of depression: A systematic overview of a 'Meta
The paper gives a complete overview of what is known about therapies for depression. ... Over the past 16 years, we have developed a 'Meta-analytic Research Domain' (MARD) of all randomized trials of psychological treatments of depression. ... Published meta-analyses and summary of outcomes.
A journey into the causes and effects of depression
The causes of depression are manifold and complex. But biologically definable factors are starting to come to light. One theory that is gaining support is that the culprit might be a slowdown in ...
The serotonin theory of depression: a systematic umbrella ...
The serotonin hypothesis of depression is still influential. We aimed to synthesise and evaluate evidence on whether depression is associated with lowered serotonin concentration or activity in a systematic umbrella review of the principal relevant areas of research. PubMed, EMBASE and PsycINFO were searched using terms appropriate to each area ...
Treatment outcomes for depression: challenges and opportunities
Our lack of knowledge cannot be put down to a scarcity of research in existing treatments. In the past decades, more than 500 randomised trials have examined the effects of antidepressant medications, and more than 600 trials have examined the effects of psychotherapies for depression (although comparatively few are conducted for early-onset depression).
Depression
Major depression is a common illness that severely limits psychosocial functioning and diminishes quality of life. In 2008, WHO ranked major depression as the third cause of burden of disease worldwide and projected that the disease will rank first by 2030.1 In practice, its detection, diagnosis, and management often pose challenges for clinicians because of its various presentations ...
(PDF) Depression
Abstract. Major depression is a mood disorder characterized by a sense of inadequacy, despondency, decreased activity, pessimism, anhedonia and sadness where these symptoms severely disrupt and ...
(PDF) Depression: A Literature Review on Diagnosis ...
This article summarizes data on the prevalence and diagnosis of depression as well as findings from research regarding recovery and relapse from depression. It also offers a summary of models of ...
The Experience of Depression: A Qualitative Study of Adolescents With
To improve our understanding, some research has been undertaken in which YP themselves are asked about their experience of depression. In a questionnaire study involving adolescents with depression in New Zealand, the researchers identified the aforementioned irritability as the most common characteristic alongside interpersonal problems and ...
Depression in young people
Depression rates in young people have risen sharply in the past decade, especially in females, which is of concern because adolescence is a period of rapid social, emotional, and cognitive development and key life transitions. Adverse outcomes associated with depression in young people include depression recurrence; the onset of other psychiatric disorders; and wider, protracted impairments in ...
A review of bodily dysfunction in depression: Empirical findings
Research suggests that depression is associated with both bodily and emotional dysfunction.Concerning bodily dysfunction, research has linked depression to increased inflammation, endocrine dysfunction, abnormalities in the motoric system (e.g., reduced walking speed), and alterations in the autonomic nervous system (Alvares et al., 2016; Dowlati et al., 2010; Elkjær et al., 2022; Michalak et ...
A Literature Review of Studies of Depression and Treatment Outcomes
According to the fall 2007 American College Health Association-National College Health Assessment ( 1), a national survey of approximately 20,500 college students on 39 campuses, 43.2% of the students reported "feeling so depressed it was difficult to function" at least once in the past 12 months.More than 3,200 university students reported being diagnosed as having depression, with 39.2% of ...
Effectiveness of physical activity interventions for improving
Objective To synthesise the evidence on the effects of physical activity on symptoms of depression, anxiety and psychological distress in adult populations. Design Umbrella review. Data sources Twelve electronic databases were searched for eligible studies published from inception to 1 January 2022. Eligibility criteria for selecting studies Systematic reviews with meta-analyses of randomised ...
Original research: Psychological factors for the onset of depression: a
These variables were considered clinically relevant to major depression. 61-63 Sensitivity analyses were conducted to examine if potential outliers, research designs and low-quality studies, affected the pooled effect sizes. The minimum number of studies was set at three studies for the main and subgroup analyses, and 10 for meta-regression.
Global Prevalence of Depressive and Anxiety Symptoms in Children and
Emerging research 42 suggests that in families using more routines during COVID-19, lower child depression and conduct problems are observed. Thus, a tangible solution to help mitigate the adverse effects of COVID-19 on youth is working with children and families to implement consistent and predictable routines around schoolwork, sleep, screen ...
Depression: Latest Research
Depression: The Latest Research. If you're one of more than 17 million adults or 3.2 million teens in the United States with major depression, you may know that treatment often falls short. The ...
Crisis in Research
Crisis in Research and Treatment Depression is among the most serious health problems facing our society, causing untold human suffering and enormous economic costs. Despite its prevalence, depression is misunderstood, under-funded and under-researched. Current treatments for depression remain severely limited. Since the introduction of Prozac nearly 30 years ago, there have been no new ...
Understanding Depression and Managing It Effectively
Key points. Depression is a multi-faceted condition affecting every aspect of life, requiring personalized treatment. Depression's causes can be biological, psychological, and social; it is not ...
Mental Health Outcomes in Transgender and Nonbinary Youths Receiving
We disagree with the commenter's summary of the literature and provide the following references in support of our stated position in this paper. Notable, the two reviews cited do not include studies 1-11 referenced below, and therefore, their conclusions do not consider the full evidence-base. 1. Turban et al. (2022).
Depression and Pain Relief With Ketamine in Patients With Chronic
Data are presented as mean (SEM). Missing data for mean pain intensity are imputed with the last-observation-carried-forward method. The dark blue line represents patients with a Hospital Anxiety and Depression Scale (HADS) score ≥11 (definite case) (n = 123); orange dashed line, patients with a HADS score of 8-10 (suspected case) (n = 77); and light blue dotted line, patients with a HADS ...
Ketamine for the treatment of major depression: a systematic review and
Therefore, clinics and research studies should adopt protocols that ensure adequate dosing when giving ketamine for depression. Introduction Ketamine, an n-methyl- d -aspartate antagonist commonly used as an anaesthetic agent, has emerged as a new treatment for depression, with efficacy demonstrated in severe and treatment-resistant depression.
Revolutionizing the Study of Mental Disorders
President George H. W. Bush proclaimed the 1990s "The Decade of the Brain ," urging the National Institutes of Health, the National Institute of Mental Health (NIMH), and others to raise awareness about the benefits of brain research. "Over the years, our understanding of the brain—how it works, what goes wrong when it is injured or diseased—has increased dramatically.
A breakthrough in research on depression screening: from validation to
Introduction. Depression affects more than two hundred sixty million people across the world and is a leading cause of disability ().The estimated prevalence of depressive disorders in 2016 was 3,627 per 100,000 and in the last decade the number of all-age years lived with disability (YLDs) increased of 14% (2,3).Resulting from a complex interaction of social, psychological and biological ...
Kids' mental health is in crisis. Here's what psychologists are doing
The Covid-19 pandemic era ushered in a new set of challenges for youth in the United States, leading to a mental health crisis as declared by the United States surgeon general just over a year ago.But U.S. children and teens have been suffering for far longer. In the 10 years leading up to the pandemic, feelings of persistent sadness and hopelessness—as well as suicidal thoughts and ...
We fact-checked Trump's recent news conference : NPR
A team of NPR reporters and editors reviewed the transcript of last Thursday's news conference and found at least 162 misstatements, exaggerations and outright lies in 64 minutes.
COMMENTS
In this paper, we describe and present the vast, fragmented, and complex literature related to this topic. This review may be used to guide practice, public health efforts, policy, and research related to mental health and, specifically, depression. ... This paper discusses key areas in depression research; however, an exhaustive discussion of ...
3.5. Meta-Analyses on Anxiety, Depression and SF Summary Scores . In total, eight studies on adults were included in a supplementary meta-analyses of several research questions on SF PCS and MCS in association with anxiety and depressive disorders. Forest plots for the analyses are provided in the supplementary materials (Figures S1-S10).
In this essay, we have briefly reviewed a selected range of key discoveries that neuroscientific research has made on the topic of depressive disorders in the last decades. We have shown that depression has been linked to a wide range of abnormalities on different levels of neuroscientific description ranging from molecules and cells to brain ...
The idea that depression is the result of abnormalities in brain chemicals, particularly serotonin (5-hydroxytryptamine or 5-HT), has been influential for decades, and provides an important ...
Running Head: Explanations of Depression. Abstract. The current paper critically evaluates Beck and Bredemeier's (2016) Unified Model of. Depression (UMD) and explores some of the wider issues ...
Econometric analysis of the relationship between vitamin D deficiency and depression was performed by Yunzhi et al. and Shauni et al. performed a bibliometric analysis of domestic and international research papers on depression-related genes from 2003 to 2007. A previous review of depression-related bibliometric studies revealed that there is ...
The paper gives a complete overview of what is known about therapies for depression. ... Over the past 16 years, we have developed a 'Meta-analytic Research Domain' (MARD) of all randomized trials of psychological treatments of depression. ... Published meta-analyses and summary of outcomes.
The causes of depression are manifold and complex. But biologically definable factors are starting to come to light. One theory that is gaining support is that the culprit might be a slowdown in ...
The serotonin hypothesis of depression is still influential. We aimed to synthesise and evaluate evidence on whether depression is associated with lowered serotonin concentration or activity in a systematic umbrella review of the principal relevant areas of research. PubMed, EMBASE and PsycINFO were searched using terms appropriate to each area ...
Our lack of knowledge cannot be put down to a scarcity of research in existing treatments. In the past decades, more than 500 randomised trials have examined the effects of antidepressant medications, and more than 600 trials have examined the effects of psychotherapies for depression (although comparatively few are conducted for early-onset depression).
Major depression is a common illness that severely limits psychosocial functioning and diminishes quality of life. In 2008, WHO ranked major depression as the third cause of burden of disease worldwide and projected that the disease will rank first by 2030.1 In practice, its detection, diagnosis, and management often pose challenges for clinicians because of its various presentations ...
Abstract. Major depression is a mood disorder characterized by a sense of inadequacy, despondency, decreased activity, pessimism, anhedonia and sadness where these symptoms severely disrupt and ...
This article summarizes data on the prevalence and diagnosis of depression as well as findings from research regarding recovery and relapse from depression. It also offers a summary of models of ...
To improve our understanding, some research has been undertaken in which YP themselves are asked about their experience of depression. In a questionnaire study involving adolescents with depression in New Zealand, the researchers identified the aforementioned irritability as the most common characteristic alongside interpersonal problems and ...
Depression rates in young people have risen sharply in the past decade, especially in females, which is of concern because adolescence is a period of rapid social, emotional, and cognitive development and key life transitions. Adverse outcomes associated with depression in young people include depression recurrence; the onset of other psychiatric disorders; and wider, protracted impairments in ...
Research suggests that depression is associated with both bodily and emotional dysfunction.Concerning bodily dysfunction, research has linked depression to increased inflammation, endocrine dysfunction, abnormalities in the motoric system (e.g., reduced walking speed), and alterations in the autonomic nervous system (Alvares et al., 2016; Dowlati et al., 2010; Elkjær et al., 2022; Michalak et ...
According to the fall 2007 American College Health Association-National College Health Assessment ( 1), a national survey of approximately 20,500 college students on 39 campuses, 43.2% of the students reported "feeling so depressed it was difficult to function" at least once in the past 12 months.More than 3,200 university students reported being diagnosed as having depression, with 39.2% of ...
Objective To synthesise the evidence on the effects of physical activity on symptoms of depression, anxiety and psychological distress in adult populations. Design Umbrella review. Data sources Twelve electronic databases were searched for eligible studies published from inception to 1 January 2022. Eligibility criteria for selecting studies Systematic reviews with meta-analyses of randomised ...
These variables were considered clinically relevant to major depression. 61-63 Sensitivity analyses were conducted to examine if potential outliers, research designs and low-quality studies, affected the pooled effect sizes. The minimum number of studies was set at three studies for the main and subgroup analyses, and 10 for meta-regression.
Emerging research 42 suggests that in families using more routines during COVID-19, lower child depression and conduct problems are observed. Thus, a tangible solution to help mitigate the adverse effects of COVID-19 on youth is working with children and families to implement consistent and predictable routines around schoolwork, sleep, screen ...
Depression: The Latest Research. If you're one of more than 17 million adults or 3.2 million teens in the United States with major depression, you may know that treatment often falls short. The ...
Crisis in Research and Treatment Depression is among the most serious health problems facing our society, causing untold human suffering and enormous economic costs. Despite its prevalence, depression is misunderstood, under-funded and under-researched. Current treatments for depression remain severely limited. Since the introduction of Prozac nearly 30 years ago, there have been no new ...
Key points. Depression is a multi-faceted condition affecting every aspect of life, requiring personalized treatment. Depression's causes can be biological, psychological, and social; it is not ...
We disagree with the commenter's summary of the literature and provide the following references in support of our stated position in this paper. Notable, the two reviews cited do not include studies 1-11 referenced below, and therefore, their conclusions do not consider the full evidence-base. 1. Turban et al. (2022).
Data are presented as mean (SEM). Missing data for mean pain intensity are imputed with the last-observation-carried-forward method. The dark blue line represents patients with a Hospital Anxiety and Depression Scale (HADS) score ≥11 (definite case) (n = 123); orange dashed line, patients with a HADS score of 8-10 (suspected case) (n = 77); and light blue dotted line, patients with a HADS ...
Therefore, clinics and research studies should adopt protocols that ensure adequate dosing when giving ketamine for depression. Introduction Ketamine, an n-methyl- d -aspartate antagonist commonly used as an anaesthetic agent, has emerged as a new treatment for depression, with efficacy demonstrated in severe and treatment-resistant depression.
President George H. W. Bush proclaimed the 1990s "The Decade of the Brain ," urging the National Institutes of Health, the National Institute of Mental Health (NIMH), and others to raise awareness about the benefits of brain research. "Over the years, our understanding of the brain—how it works, what goes wrong when it is injured or diseased—has increased dramatically.
Introduction. Depression affects more than two hundred sixty million people across the world and is a leading cause of disability ().The estimated prevalence of depressive disorders in 2016 was 3,627 per 100,000 and in the last decade the number of all-age years lived with disability (YLDs) increased of 14% (2,3).Resulting from a complex interaction of social, psychological and biological ...
The Covid-19 pandemic era ushered in a new set of challenges for youth in the United States, leading to a mental health crisis as declared by the United States surgeon general just over a year ago.But U.S. children and teens have been suffering for far longer. In the 10 years leading up to the pandemic, feelings of persistent sadness and hopelessness—as well as suicidal thoughts and ...
A team of NPR reporters and editors reviewed the transcript of last Thursday's news conference and found at least 162 misstatements, exaggerations and outright lies in 64 minutes.