research papers in obstetrics and gynaecology

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Obstetrics and gynecology

• Women's health
• Assisted reproductive technology
• Contraception
• Female subfertility
• Gynecologic cancers
• Gynecologic diseases
• Gynecologic infections
• Menstrual abnormalities
• Obstetric anesthesiology
• Stillbirths
• Termination of pregnancy
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Vocational identity in decision-making for terminating/continuation of pregnancy following non-invasive prenatal testing and hypothetical diagnosis among Japanese university students

Shodai Sunagozaka, Atsuro Tsutsumi

Causal association of menstrual reproductive factors on the risk of osteoarthritis: A univariate and multivariate Mendelian randomization study

Xinzhe Tan, Yifang Mei,  [ ... ], Dongyan Wang

Narratives of pregnancy across 19 Countries: Analysis of a 1.5-billion-word news media database

Kalla Maxine P. Sy, Ting Yu Joanne Chow, Jeannette R. Ickovics, Reuben Ng

Prenatal coparenting and attachment style in Japanese pregnant women: A cross-sectional survey

Yui Masui, Akemi Yamazaki

Comparison of early and fully expanded blastocysts on pregnancy and birth outcomes in patients with fresh IVF/ICSI cycles: A retrospective cohort study

Xiaoqin Pan, Yuanping Zhou, Liwen Shen

Promotion and COVID-19 lockdown increase uptake of funded maternal pertussis vaccination in pharmacy: A mixed methods study

Natalie J. Gauld, Cath Knapton, Owen Sinclair, Cameron C. Grant

Predictors of low birthweight and comparisons of newborn birthweights among different groups of maternal factors at Rev. John Chilembwe Hospital in Phalombe district, Malawi: A retrospective record review

Dumisani Mfipa, Precious L. Hajison, Felistas Mpachika-Mfipa

Use of drama for improving breastfeeding initiation, exclusive breastfeeding and breastfeeding self-efficacy among rural pregnant women from selected communities in two Local Government Areas (LGAs) in Ibadan, Nigeria

Yetunde Omotola Ogundairo, Adepoju Oladejo Thomas, Olumide Adesola Olufunmilola

A mixed-method analysis of provider adherence to integrated antenatal care guideline in BEmONC and Non BEmONC primary health center: An Indonesian case

Suryani Yuliyanti, Adi Utarini, Laksono Trisnantoro

Platelet and epithelial cell interations can be modeled in cell culture, and are not affected by dihomo-gamma-linolenic acid

Zitha Redempta Isingizwe, Laura F. Mortan, Doris Mangiaracina Benbrook

Geospatial patterns, and individual and community levels factors of cesarean section deliveries in Ethiopia: A spatial and multilevel analysis

Abel Endawkie, Shimels Derso Kebede,  [ ... ], Yawkal Tsega

The trajectory of body image dissatisfaction during pregnancy and postpartum and its relationship to Body-Mass-Index

Katja Linde, Franziska Lehnig,  [ ... ], Anette Kersting

Factors related to blood pressure assessment during pregnancy in Ethiopia: Multilevel analysis using the 2019 mini demographic and health survey data

Tigabu Kidie Tesfie, Bantie Getnet Yirsaw,  [ ... ], Werkneh Melkie Tilahun

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Obstetrics & Gynecology Journals

Our journals offer timely, authoritative, international, and relevant information to stay informed about the latest trends and developments in your field.

Elsevier’s Ob/Gyn Portfolio features a wide range of journals devoted to the rapid publication of research on all aspects of women’s health, obstetrics and gynecology, reproductive biology, maternal-fetal medicine, perinatology, gynecologic oncology, sexual medicine, infertility, reproductive endocrinology, placental development, embryogenesis, reproductive immunology, postreproductive health, reproductive ethics and more.

Timely, authoritative, international and relevant, these journals provide the critical information that will help keep you up to date with the latest trends and developments in your field.

AJOG Global Reports opens in new tab/window

American Journal of Obstetrics & Gynecology opens in new tab/window

American Journal of Obstetrics & Gynecology MFM opens in new tab/window

Best Practice & Research Clinical Obstetrics & Gynaecology opens in new tab/window

Case Reports in Women's Health opens in new tab/window

Contraception opens in new tab/window

Contraception: X opens in new tab/window

European Journal of Obstetrics & Gynecology and Reproductive Biology opens in new tab/window

European Journal of Obstetrics & Gynecology and Reproductive Biology: X opens in new tab/window

Fertility and Sterility opens in new tab/window

F&S Reports opens in new tab/window

F&S Reviews opens in new tab/window

F&S Science opens in new tab/window

Gynecologic Oncology opens in new tab/window

Gynécologie Obstétrique Fertilité & Sénologie opens in new tab/window

Journal of Endometriosis and Uterine Disorders opens in new tab/window

Journal of Gynecology Obstetrics and Human Reproduction opens in new tab/window

Journal of Minimally Invasive Gynecology opens in new tab/window

Journal of Obstetrics and Gynaecology Canada opens in new tab/window

Journal of Pediatric and Adolescent Gynecology opens in new tab/window

Journal of Reproductive Immunology opens in new tab/window

Maturitas opens in new tab/window

Midwifery opens in new tab/window

Obstetrics and Gynecology Clinics of North America opens in new tab/window

Obstetrics, Gynaecology and Reproductive Medicine opens in new tab/window

Paediatrics and Child Health opens in new tab/window

Placenta opens in new tab/window

Pregnancy Hypertension opens in new tab/window

Reproductive BioMedicine Online opens in new tab/window

Seminars in Fetal & Neonatal Medicine opens in new tab/window

Seminars in Perinatology opens in new tab/window

Sexual & Reproductive Healthcare opens in new tab/window

Taiwanese Journal of Obstetrics & Gynecology opens in new tab/window

Women and Birth opens in new tab/window

Women's Health Issues opens in new tab/window

Open access options

Open access lies at the core of Elsevier’s publishing mission – in fact, today, almost all of our journals offer open access options. That means finding the right open access home for your research is easy.

Whatever route you choose, publishing with Elsevier means your work benefits from the input of expert editors and reviewers. And if you publish gold open access, it is immediately and permanently free for everyone to read and download from ScienceDirect. Our gold OA titles also feature in major indexes and databases.

The following journals are fully Open Access:

Case Reports in Women’s Health opens in new tab/window

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Stay updated on the latest research in Obstetrics & Gynecology, follow us on Twitter at  @ObGynAdvance opens in new tab/window .

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Latest Articles

The editors of this journal are pleased to offer electronic publication of accepted papers prior to issue publication. These papers can be cited using the date of access and the unique DOI number. Any final changes in manuscripts will be made at the time of issue publication and will be reflected in the final electronic version of the issue.

Disclaimer : Articles appearing in this Latest Articles section have been peer-reviewed and accepted for publication in this journal and posted online before issue publication. Articles appearing here may contain statements, opinions, and information that have errors in facts, figures, or interpretation. Accordingly, Wolters Kluwer, the editors and authors and their respective employees are not responsible or liable for the use of any such inaccurate or misleading data, opinion or information contained the articles in this section.

Original Research

Glycemic Control and Risk of Congenital Malformations in Women With Type 1 Diabetes

September 5, 2024

• Abstract Abstract
• In Brief In Brief
• Permissions

Association Between Metformin Use in Early Gestational or Type 2 Diabetes in Pregnancy and Preterm Preeclampsia

Body mass index changes among adolescents and young adults using the etonogestrel contraceptive implant.

August 30, 2024

Research Letter

Changes in Prenatal Cannabis Use Among Pregnant Individuals From 2012 to 2022

Go to Full Text of this Article

Systematic Review

Human Papillomavirus Vaccination in the Postpartum Period: A Systematic Review

August 29, 2024

Clinical Perspective

Integrated Strategies to Support Diabetes Technology in Pregnancy

Narrative Review

Treatment of Diabetes in Pregnancy With Metformin

Correlation of polycystic ovarian syndrome phenotypes with pregnancy and neonatal outcomes.

August 22, 2024

Conservative Management of Placenta Accreta Spectrum and Breast-Milk Production

Fellowship for academic generalists in obstetrics and gynecology: is it overdue, prenatal care utilization and birth outcomes after expansion of the national health service corps, pregnancy outcomes in patients with hepatitis c virus infection, utility and outcomes of ovarian tissue cryopreservation and transplantation for gynecologic cancers: a systematic review and meta-analysis.

Clinical Expert Series

Management of Red Cell Alloimmunization in Pregnancy

August 15, 2024

Rising Stillbirth Rates Related to Congenital Syphilis in the United States From 2016 to 2022

Prenatal care clinician preferences among patients with spanish-preferred language, barbed sutures compared with conventional sutures during laparoscopic myomectomy: a systematic review and meta-analysis, standard compared with extended red blood cell antigen matching for prevention of subsequent hemolytic disease of the fetus and newborn: a systematic review.

August 8, 2024

Virtual Compared With In-Office Postoperative Visits After Urogynecologic Surgery: A Randomized Controlled Trial

Evaluation of statewide program to reduce cesarean deliveries among nulliparous individuals with singleton pregnancies at term gestation in vertex presentation.

August 1, 2024

Advancing and Transforming Women's Health

Turning back the clock on human cells Learn more

Funding awarded to create 3D Human Placental Development Model Learn more

Landmark LGBTQ study comes to Stanford Learn more

Elective induction at 39 weeks reduces need for cesarean deliveries Learn more

Stanford Medicine's Department of Obstetrics and Gynecology  research program lies at the nexus of what is current and what is possible for women’s health, seeking to answer the most human of questions. Our basic scientists navigate the complexities of reproductive endocrinology, stem cell biology, and ovarian cancer. Our translational researchers transform these discoveries into novel therapies for cancer therapy, and reproductive, perinatal, and regenerative medicine. Clinical community participation researchers investigate health outcomes across the lifespan and offer new treatment and research methodologies that allow women and sexual and gender minorities greater opportunity to take ownership of their health.

Our discoveries are driven by compassion and innovation, with a longstanding history of practice-changing breakthroughs in reproductive & stem cell biology and women’s health. We were among the first to pioneer embryo cryopreservation methodology and frozen blastocyst biopsy, affording new possibilities in fertility preservation and treatment . Our research teams have applied the use of pluripotent stem cells to novel treatments including smooth muscle cell regeneration, and developmental syndrome therapies. Our perinatologists were instrumental in the creation and application of Non-Invasive Prenatal Testing. Our Family Planning researchers have revolutionized the access and affordability of birth control options, working at a global scale.

We have the privilege of residing at the heart of Stanford University and Silicon Valley, affording us the capacity for unique research partnerships. We collaborate both within the School of Medicine and across the University. Our physician scientists are uniquely poised to work with industry leaders to transform women’s health. Our location and collaborators precipitate diverse ideas and provide access to diverse populations, ensuring research that is truly interdisciplinary and innovative. 

Complex Family Planning

Expanding access to abortion and contraception through research that challenges the status quo.

Gynecology Oncology

Uncovering the future of treatment for women's cancers through breakthrough trials and immunotherapy.

Maternal and Fetal Medicine

Advancing the care for maternal, placental and fetal disorders through innovative interdisciplinary exploration and collaboration.

Reproductive Endocrinology & Infertility

Developing groundbreaking techniques to understand and support reproductive health.

Reproductive, Stem Cell and Perinatal Biology

Building interdisciplinary research programs investigating the mechanisms of human reproduction, pregnancy, and pluripotent stem cell applications.

Urogynecology and Pelvic Reconstructive Surgery

Investigating the underlying factors influencing pelvic health, and devising compassionate and novel treatment for female genitourinary conditions.

Obstetrics and Gynecology Clinical Research Unit offers peer review and mentorship for protocol development and grant submissions. 

The PRIDE Study is supported by the community engagement efforts of PRIDEnet, a national network of individuals and organizations that engage LGBTQ+ people in health research.

Faculty Labs

• El-Sayed Research
• Fertility and Pregnancy Loss - Directed by  Dr. Lathi
• Sebastiano Lab

The Journal of Obstetrics and Gynaecology Research (JOGR)

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Please be informed that JOGR Volume 50, Issue 8 has been published and Editor's choice has been updated here; https://obgyn.onlinelibrary.wiley.com/toc/14470756/current https://obgyn.onlinelibrary.wiley.com/doi/toc/10.1111/(ISSN)1447-0756.editors-choice

Below Editor’s choice article from this issue are free until the end of August 2024. https://doi.org/10.1111/jog.15944

And below Editor’s choice article from the same issue is Open Access. https://doi.org/10.1111/jog.15995 https://doi.org/10.1111/jog.15975

For your further information, below article is especially gathering attention from relevant academic societies in Japan and Wiley is promoting this article to global researchers as well. https://obgyn.onlinelibrary.wiley.com/doi/10.1111/jog.15626 H. Yahata et al. Study of the effects of in-person attendance at academic conferences on the health of the attendees under COVID-19 pandemic

The Journal of Obstetrics and Gynaecology Research is the official Journal of the Asia and Oceania Federation of Obstetrics and Gynaecology and of the Japan Society of Obstetrics and Gynecology.

The acceptance criteria for all papers are the quality and originality of the research and its significance to our readership. Except where otherwise stated, manuscripts are peer reviewed by anonymous reviewers and the Editor. The Editorial Board reserves the right to refuse any material for publication and advises that authors should retain copies of submitted manuscripts and correspondence as material cannot be returned. Final acceptance or rejection rests with the Editorial Board.

All articles submitted to the Journal must comply with these instructions. Failure to do so will result in return of the manuscript and possible delay in publication. Where contributions are judged as acceptable for publication on the basis of scientific content, the Editor or the Publisher reserve the right to modify typescripts to eliminate ambiguity and repetition and improve communication between author and reader. If extensive alterations are required, the manuscript will be returned to the author for revision. Manuscripts must be submitted online at http://mc.manuscriptcentral.com/jogr . For assistance, please contact the Editorial Office of The Journal of Obstetrics and Gynaecology Research at the address below:

Editorial Office of The Journal of Obstetrics and Gynaecology Research

c/o Wiley Frontier Koishikawa Bldg 4F, 1-28-1 Koishikawa, Bunkyo-ku, Tokyo 112-0002 Japan Email : [email protected] Tel : +81 3 3830 1264 Fax : +81 3 5689 7278

Authors for whom English is a second language may choose to have their manuscript professionally edited before submission to improve the English. A list of independent suppliers of editing services can be found 18 at http://authorservices.wiley.com/bauthor/english_language.asp . All services are paid for and arranged by the author, and use of one of these services does not guarantee acceptance or preference for publication

Submitting a cover letter is not mandatory, but it is helpful if the author provides any information which may facilitate the editorial process. The Editors encourage the authors to explain in the cover letter why their paper should be published in JOGR. Completion and inclusion of the Manuscript Submission Check form is obligatory with the submission of all categories of article. If the form is not included or complete, the manuscript will not be considered for peer review. The corresponding author must submit this form the "Manuscript Submission Check form" on behalf of all co-authors.

In keeping with the latest guidelines of the International Committee of Medical Journal Editors, each author's contribution to the paper is to be quantified. Authors must state their study does not violate the policies and/or procedures established by journal such as those described in 'Specific Inappropriate Acts in Publication Process' click here and also state that the protocol for the research project has been approved by a suitably constituted Ethics Committee of the institution within which the work was undertaken and that it conforms to the provisions of the Declaration of Helsinki (as revised in Tokyo 2004), available at http://www.wma.net/en/30publications/10policies/b3/index.html .

Nonetheless the research has been approved by Ethic Committee, Associate Editors may reject manuscripts when editors judge there has been a problem ethically. All investigations on human subjects must include a statement that the subject gave informed consent and patient anonymity should be preserved. In general, submission of a case report can be accompanied by the written consent of the subject (or parent/guardian) prior to publication; this is particularly important where photographs are to be used or in cases where the unique nature of the incident reported makes it possible for the patient to be identified. While the Editorial Board recognizes that it might not always be possible or appropriate to seek such consent, the onus will be on the authors to demonstrate that this exception applies in their case. Any experiments involving animals must be demonstrated to be ethically acceptable and where relevant conform to national guidelines for animal usage in research. Authors should declare any financial support or relationships that may pose potential conflict of interest.

When authors submit a manuscript reporting work that has already been reported in large part in a published article or is contained in or closely related to another paper that has been submitted or accepted for publication elsewhere, the letter or submission form should clearly say so and the authors should provide copies of the related material to help the editor decide how to handle the submission. This recommendation does not prevent a journal from considering a complete report that follows publication of a preliminary report, such as a letter to the editors or an abstract or poster displayed at a scientific meeting. It also does not prevent journals from considering a paper that has 19 been presented at a scientific meeting but was not published in full, or that is being considered for publication in proceedings or similar format. Press reports of scheduled meetings are not usually regarded as breaches of this rule, but they may be if additional data tables or figures enrich such reports. Authors should also consider how dissemination of their findings outside of scientific presentations at meetings may diminish the priority journal editors assign to their work.

Authors should declare any financial support or relationship that may pose conflict of interest as a Conflict of Interest Statement in the Disclosure section of your manuscript according to the new guideline and confirm that the results of this manuscript have not been distorted by research funding or conflicts of interest. Please visit this link for further details: Disclosure form click here.

Completion and inclusion of Disclosure Form is obligatory with the submission of all categories of article. If the form is not included or complete, the manuscript will not be considered for peer review.

Accepted papers will be passed to Wiley's production team for publication. The author identified as the formal corresponding author for the paper will receive an email prompting them to login into Wiley's Author Services, where via the Wiley Author Licensing Service (WALS) they will be asked to complete an electronic license agreement on behalf of all authors on the paper.

Authors may choose to publish under the terms of the journal's standard copyright transfer agreement (CTA), or under open access terms made available via Wiley OnlineOpen.

Standard Copyright Transfer Agreement : FAQs about the terms and conditions of the standard CTA in place for the journal, including standard terms regarding archiving of the accepted version of the paper, are available at: Copyright Terms and Conditions FAQs.

OnlineOpen - Wiley's Open Access Option : OnlineOpen is available to authors of articles who wish to make their article freely available to all on Wiley Online Library under a Creative Commons license. With OnlineOpen, the author, the author's funding agency, or the author's institution pays a fee to ensure that the article is made open access. Authors of OnlineOpen articles are permitted to post the final, published PDF of their article on their personal website, and in an institutional repository or other free public server immediately after publication. All OnlineOpen articles are treated in the same way as any other article. They go through the journal's standard Journal of Obstetrics and Gynaecology Research Instructions for Author Update December 2014 peer-review process and will be accepted or rejected based on their own merit.

OnlineOpen licenses : Authors choosing OnlineOpen retain copyright in their article and have a choice of publishing under the following Creative Commons License terms: Creative Commons Attribution License (CC BY); Creative Commons Attribution Non- Commercial License (CC BY NC); Creative Commons Attribution Non-Commercial20 NoDerivs License (CC BY NC ND). To preview the terms and conditions of these open access agreements please visit the Copyright Terms and Conditions FAQs. If you select the OnlineOpen option and your research is funded by certain funders [e.g. The Wellcome Trust and members of the Research Councils UK (RCUK) or the Austrian Science Fund (FWF)] you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with your Funder requirements. Funder Open Access and Self-Archiving Compliance: Please click here for more information on Wiley's compliance with specific Funder Open Access and Self Archiving Policies, and click here click here for more detailed information specially about Self- Archiving definitions and policies

Submission should be, double-space, on one side only of A4 paper. The top bottom and side margins should be 30 mm. All the pages should be numbered consecutively in the top right-hand corner, beginning with the title page. Indent new paragraphs. Turn the hyphenation option off, including only those hyphens that are essential to the meaning. Please use Word's 'Save As' option to save our document as an older (.doc) file type. After submission, authors cannot be changed or modified.

Original articles

Original articles should provide full-length reports of current research in either basic or clinical science. The length of an article (including references, tables and appendices etc.) should not exceed 5000 words. The maximum number of authors is ten (10), if you wish to include more than ten (10) authors, please explain the reason in your and describe the individual contribution of each author.

Case reports

Case reports should provide new information that enhances our knowledge of the clinical aspects of Obstetrics and Gynecology. In principle, reports of a very rare case will be accepted; however the following reports will not: (i) a rare case that is presented that does not add significantly new information regarding diagnosis and treatment of the disease; and (ii) when a considerable number of articles reporting similar cases have been already published. Authors are requested to clarify in the Discussion section what readers can learn from the case. Information that can be linked to the patients' identification must be carefully masked. Case reports should not exceed 2000 words (including 150 words abstract, up to 15 references). Figures/tables should be up to 3 in total. The maximum number of authors is six (6), if you wish to include more than six (6) authors, please explain the reason in your cover letter and describe the individual contribution of each author.

Letters to the Editor

Two styles of Letter to the Editor will be considered for publication: i) Letters that reference an article published in The Journal of Obstetrics and Gynaecology Research. Letters are to be submitted online no more than 3 months after the date of the issue in which the related article appeared; ii) Discourse that sheds light on the understanding of the study of Obstetrics and Gynecology in the Asia and Oceania region. This should be structured as a letter to the Editor-in-Chief. Letters should be brief and contain no 21 more than 400 words and 1-4 references. All data presented in the letter must be fully citable and listed as a supporting reference. Letters should be signed by no more than three authors.

Review Articles

Reviews are authoritative analyses of specific topics. Their references should cover the existing literature and include recent studies. Word limit is 5,000 words maximum including abstract.

Manuscripts should follow the style of the Vancouver agreement detailed in the International Committee of Medical Journal Editors' revised 'Uniform Requirements for Manuscripts Submitted to Biomedical Journals: Writing and Editing for Biomedical Publication', as presented athttp://www.ICMJE.org/. The Journal uses US spelling and authors should therefore follow the latest edition of the Merriam-Webster's Collegiate Dictionary. All measurements must be given in SI units. Abbreviations should be used sparingly and only where they ease the reader's task by reducing repetition of long, technical terms. Initially use the word in full, followed by the abbreviation in parentheses. Thereafter use the abbreviation. Upon its first use in the title, abstract and text, the common name of a species should be followed by the scientific name (genus, species and authority) in parentheses. However, for well-known species, the scientific name may be omitted from the article title. If no common name exists in English, the scientific name should be used only. Drugs should be referred to by their generic names, rather than brand names.

Equations should be numbered sequentially with Arabic numerals; these should be ranged right in parentheses. All variables should appear in italics. Use the simplest possible form for all mathematical symbols.

Manuscripts should be presented in the following order: (i) title page, (ii) abstract and key words, (iii) text, (iv) acknowledgments, (v) disclosure, (vi) references, (vii) appendices, (viii) figure legends, (ix) tables (each table complete with title and footnotes) and (x) figures. Footnotes to the text are not allowed and any such material should be incorporated into the text as parenthetical matter.

As articles are reviewed single-blind, material that might identify authorship of the paper should be placed on a cover sheet which will be detached before the paper is sent to referees. The title page should contain (i) the title of the paper, (ii) the full names of the authors and (iii) the addresses of the institutions at which the work was carried out together with (iv) the full postal and email address, plus facsimile and telephone numbers, of the author to whom correspondence about the manuscript, proofs and requests for offprints should be sent. The present address of any author, if different from that where the work was carried out, should be supplied in a footnote. The title should be short, informative and contain the major key words. A short running title (fewer than 40 characters, including spaces) should also be provided.

Abstract and key words

All articles except case reports must have a structured abstract that states in 250 words or fewer the purpose, basic procedures, main findings and principal conclusions of the study. Divide the abstract with the headings Aim, Methods, Results, Conclusions. Case reports should have an unstructured abstract of 150 words or fewer. The title of the article should be described on the top of the abstract. The abstract should not contain abbreviations or references. Five key words (for the purposes of indexing) should be supplied below the abstract, in alphabetical order, and should be taken from those recommended by the US National Library of Medicine's Medical Subject Headings (MeSH) browser list (http://www.nlm.nih.gov/mesh/meshhome.html).

Authors should use subheadings to divide the sections of their manuscript: Introduction, Methods, Results, Discussion, Acknowledgments, Disclosure, References.

Acknowledgments

The source of financial grants and other funding should be acknowledged, including a frank declaration of the authors' industrial links and affiliations. The contribution of colleagues or institutions should also be acknowledged. Thanks to anonymous reviewers are not allowed.

At the time of submission, the Corresponding author must include a disclosure statement in the body of the manuscript. The statement will describe all of the authors' relationships with the companies that may have a financial interest in the information contained in the manuscript. This information should be provided under the heading titled 'Disclosure' which should appear after the 'Acknowledgements' section and before the 'References' section. The absence of any interest to disclose must also be stated.

We recommend the use of a tool such as EndNote or Reference Manager for reference management and formatting. EndNote reference styles can be searched for here:http://endnote.com/downloads/styles Reference Manager Reference styles can be searched for here:http://www.refman.com/support/rmstyles.asp The Vancouver system of referencing should be used. In the text, references should be cited using superscript Arabic numerals in the order in which they appear. If cited only in tables or figure legends, number them according to the first identification of the table or figure in the text. In the reference list, the references should be numbered and listed in order of appearance in the text. Cite the names of all authors when there are six or fewer; when seven or more list the first three followed by et al. Names of journals should be abbreviated in the style used in Index Medicus. Reference to unpublished data and personal communications should not appear in the list but should be cited in the text only (e.g. Smith A, 2000, unpublished data).

1. Standard Journal article

Dunn JM. A large mesenteric cyst complicating pregnancy. JAMA 1967; 200: 1129-1131.

2. Standard journal article using DOI; articles published online in advance without volume, issue, or page number. The DOI will remain valid and allow an article to be tracked even after its allocation to an issue. (More information about DOIs: http://www.doi.org/faq/html):

Furuya R, Takahashi R, Furuya S, et al. Is urethritis accompanied by seminal vescu-litis? Int. J. Urol. Published online: 12 May 2009;DOI:10.1111/j.1442-2042.2009.02314.x. Book Rock JA, Thompson JD (eds) Telende's Operative Gynecology, 8th edn. Philadelphia: Lippincott-Raven, 1996.

Chapter in a Book

Morse SS. Factors in the emergence of infectious diseases. Emerg. Infect. Dis. (Serial online). 1995 Jan-Mar; 1(1):(24 screens). [Cited 5 Jun 1996.] Available from URL: (xxx) Appendices. These should be placed at the end of the paper, numbered in Roman numerals and referred to in the text. If written by a person other than the author of the main text, the writer's name should be included below the title.

Tables should be self-contained and complement, but not duplicate, information contained in the text. Tables should be numbered consecutively in Arabic numerals. Each table should be presented with a comprehensive but concise legend. Tables should be double-spaced and vertical lines should not be used to separate columns. Column headings should be brief, with units of measurement in parentheses; all abbreviations should be defined in footnotes. Footnote symbols: †, ‡, §, ¶, should be used (in that order) and *, **, *** should be reserved for P-values. Statistical measures such as SD or SEM should be identified in the headings. The table and its legend/footnotes should be understandable without reference to the text.

All illustrations (line drawings and photographs) are classified as figures. Figures should be cited in consecutive order in the text. Line figures should be supplied as sharp, black and white graphs or diagrams, drawn professionally or with a computer graphics package; lettering should be included. Individual images forming a composite figure should be of equal contrast, to facilitate printing, and should be accurately squared. Images need to be cropped sufficiently to prevent the subject being recognized, or an eye bar used. Magnifications should be indicated using a scale bar on the illustration. Images should be supplied as high resolution (at least 300 d.p.i.) files, saved as .eps or .tif format. Digital images supplied only as low-resolution print-outs and/or files cannot be used.

Figure legends

Legends should be self-explanatory and typed on a separate page. The legend should incorporate definitions of any symbols used and all abbreviations and units of measurement should be explained so that the figure and its legend are understandable without reference to the text. (Provide a letter stating exclusive licence authorization if figures have been reproduced from another source.)

Supporting information is provided by the authors to support the content of an article but they are not integral to that article. They are hosted via a link on Wiley Online Library, but do not appear in the print version of the article. Supporting information must be submitted together with the article for review; they should not be added at a later stage. They can be in the form of tables, figures, appendices and even video footage. Reference to Supporting Information in the main body of the article is allowed. However, it should be noted that excessive reference to a piece of Supporting Information may indicate that it would be better suited as a proper reference or fully included figure/table. The materials will be published as they are supplied and will not be checked or typeset in any way. All supporting information files should come with a legend, listed at the end of the main article. Each figure and table file should not be larger than 5MB, although video files may be larger. Prior to submission, please check the guidelines at: http://authorservices.wiley.com/bauthor/suppmat.asp .

The Editor recommends the following guidelines for evidence-based reporting of randomized controlled trials, systematic reviews and meta-analyses. For reporting randomized controlled trials refer to the guidelines of The CONSORT Statement: http://www.consort-statement.org . For systematic reviews and metaanalyses refer to the guidelines of The PRISMA Statement: http://www.prismastatement . org/index.htm.

The entire article (including tables) should be supplied as a single file; only electronic figures should be supplied as separate files. The following instructions should be adhered to.

It is essential that the final, revised version of the accepted manuscript and the electronic file are identical.

Do not use the carriage return (enter) at the end of lines within a paragraph.

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Grand Challenges in Obstetrics and Gynecology

The Obstetrics and Gynecology Specialty Section of Frontiers in Medicine will welcome submissions from the clinical, basic, and translational research spheres in all sub-specialties of obstetrics and gynecology. In addition to manuscripts reporting original research, we welcome meta-analyses and narrative or expert reviews exploring noteworthy topics of clinical care and research in OB/Gyne. Case reports and case series that report remarkable findings with potentially significant impact on clinical or research endeavors, will also be considered. The performance and dissemination of research is the key to advancing individual and population health and the practice of OB/Gyne worldwide.

Many challenges are on the radar for immediate and long-range research in OB/Gyne. The Great Obstetric Syndromes continue to pose short and long-term threats to the health and wellbeing of gravidae and their offspring. The last 2 years have brought into sharp focus the hazards of infectious disease in pregnancy. Hundreds of clinical and basic research papers have delved into the impact of SARS-CoV-2 infection on parturients and fetuses. However other pathogens remain dangerous in pregnancy, such as human cytomegalovirus. Work to develop an effective CMV vaccine continues. Other, preventable diseases may see a resurgence among populations with poor vaccination coverage. Going forward, research will examine the longer-term implications of COVID in pregnancy, as well as new strategies for prenatal surveillance of fetal CMV.

Artificial intelligence, with its myriad applications, has an essential role to play in the service of OB/Gyne. Clinical and basic researchers in all our subspecialties have only begun to scratch the surface of these modalities. AI and machine learning have been used to develop prediction algorithms for use in the labor and delivery ward, for example. AI has also been applied to improve diagnosis and prognostication in ovarian cancers, by incorporating and considering multiple factors. AI shows great promise in the field of OB/Gyne imaging more broadly, in image interpretation in fetal scanning for example. In the near future, AI will provide important assistance in the provision of care across many disciplines within our specialty.

One of the areas with potential to benefit significantly from AI applications is precision medicine. Via analysis of big data it will become increasingly feasible to tailor diagnostics and treatment to the individual patient, taking into consideration all aspects of their history, background and particular needs. The experience of the last few years has highlighted the urgent necessity and the possibilities of providing services to remote or poorly served regions and populations. Remote telehealth services blossomed in response to the demands of the pandemic: the approaches developed can serve in increasing access for marginalized patient groups. Creative solutions can be enlisted to provide access to reproductive care where access is constrained.

As physicians and researchers in OB/Gyne we might think of “Outreach” in the context of programs designed to reach geographically remote communities. However outreach programs can bring life-saving and quality of life enhancing services and professional training anywhere they are needed. Creative approaches combining local knowledge and expertise with professional resources are essential to providing customized care.

Prevention, whether of obstetric complications or STI's, congenital anomalies or ovarian cancer, is a fundamental part of OB/Gyne clinical and research endeavors. Preventative medicine and investigations can take the most advanced or basic approaches, the key being to devise interventions that are shown to be suited to target populations and produce sustainable results.

Within preventative medicine, the many factors that contribute to individual risks and outcomes must be considered. Innumerable clinical trials over the course of decades excluded female subjects and thereby failed to provide evidence-based research to inform clinical practice for female patients across all disciplines. The medical community has begun to grapple with this and many other sources of systemic prejudice and bias that permeate our profession. It is imperative to identify and overcome these entrenched biases in order to deliver optimal, personalized care to individual patients. Studies focusing on clinical training in OB/Gyne, healthcare delivery, patient perception, and medical and scientific communication, among many other topics, can lay the foundation on which to develop evidence-based approaches to remediation.

An indispensable part of work in OB/Gyne—in the clinic and the lab—is imaging. Studies reporting on or applying all methodologies and modalities of imaging, including ultrasound, MRI, CT, and others, as relates to our work in OB/Gyne, whether illustrating interesting cases or technical advances, contributing to clinical diagnosis, or showing how imaging is used in the service of basic research advancement, are welcome.

We are excited to take part in this specialty section in Obstetrics and Gynecology, creating a forum for sharing and dissemination of meaningful, impactful research. We look forward to receiving your submissions.

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All authors listed have made a substantial, direct, and intellectual contribution to the work and approved it for publication.

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Regenerative medicine in Obstetrics & Gynecology: Current status under the Act on the Safety of Regenerative Medicine in Japan

Affiliations.

• 1 Department of Obstetrics and Gynecology, The Jikei University School of Medicine, 3-25-8, Nishi-shinbashi, Minato-ku, Tokyo, 105-8461, Japan.
• 2 Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan.
• 3 Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), 1-5-45, Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.
• PMID: 39228904
• PMCID: PMC11369503
• DOI: 10.1016/j.reth.2024.08.003

Introduction: While the provision of unapproved regenerative medicine has been problematic worldwide, few studies have examined the implementation status of regenerative medicine (RM) in the specific field. This study aimed to determine the current status of therapy and clinical research in the obstetrics and gynecology (OBGYN) in Japan under the Act on the Safety of Regenerative Medicine (RM Act).

Methods: Detailed data were extracted from publicly available websites provided by the Ministry of Health, Labour, and Welfare. We extracted descriptive details, including risk classification of the RM Act, modality, target disease, locality, institution, and administration route. For therapy, the price for each modality was evaluated.

Results: The total number of therapeutic provision plans in OBGYN (1.9% of RM in Japan) are classified as Class II (moderate) risk. Most were administered in clinics in urban areas for treating endometrial or ovarian infertility by locally administering platelet-rich plasma (PRP) or autologous mesenchymal stem cells (MSCs). The price using MSCs is approximately eight times more expensive that of those involving PRP (1832.1 ± 1139.8 vs 240.8 ± 106.5 thousand yen, p < 0.0001). Regarding research, four plans (2.2%) were submitted to target implantation failure and advanced gynecological cancer using autologous lymphocytes, dendritic cells, or MSCs.

Conclusion: The RM Act permits knowledge of the current status of regenerative medicine even for unapproved uses in a specific clinical field. The study findings shall prompt a worldwide discussion regarding the required regulations for therapy and clinical research of RM.

Keywords: Act on the Safety of Regenerative Medicine; Cellular therapy; Japan; Obstetrics and Gynecology; Private practice; Regenerative medicine.

© 2024 The Author(s).

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Conflict of interest statement

The authors declare that there are no conflicts of interest regarding this work.

Descriptive characteristics of regenerative medicine…

Descriptive characteristics of regenerative medicine in the field of obstetrics and gynecology in…

• Tobita M., Konomi K., Torashima Y., Kimura K., Taoka M., Kaminota M. Japan's challenges of translational regenerative medicine: act on the safety of regenerative medicine. Regen Ther. 2016;4:78–81. - PMC - PubMed
• Konomi K., Tobita M., Kimura K., Sato D. New Japanese initiatives on stem cell therapies. Cell Stem Cell. 2015;16:350–352. - PubMed
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Obstetric and Gynecological Nursing Research Paper Topics

The diverse array of obstetric and gynecological nursing research paper topics underscores the critical importance of this specialized field of nursing. Obstetric and gynecological nursing encompasses a wide range of topics that address the health and wellness of women from adolescence through menopause and beyond. This includes the management of pregnancy and childbirth, preventive care, and the diagnosis and treatment of diseases and disorders specific to women. As the healthcare needs of women continue to evolve, so does the need for ongoing research and development of evidence-based practices in obstetric and gynecological nursing. This article provides a comprehensive list of research paper topics that will be of interest to students and professionals seeking to expand their knowledge and contribute to the body of knowledge in this vital area of healthcare.

100 Obstetric and Gynecological Nursing Research Paper Topics

Obstetric and gynecological nursing is a specialized field of nursing that focuses on the health and well-being of women throughout their lifespan. It encompasses a wide range of topics including pregnancy and prenatal care, labor and delivery, postpartum care, gynecological disorders, reproductive health, maternal and newborn health, high-risk pregnancy, women’s health across the lifespan, menopausal health, and ethical and legal issues in obstetric and gynecological nursing. The significance of this field cannot be overstated as it plays a crucial role in ensuring the health and well-being of both women and newborns. This article provides a comprehensive list of obstetric and gynecological nursing research paper topics, divided into 10 categories, each containing 10 topics.

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Pregnancy and Prenatal Care:

• The role of prenatal vitamins in preventing birth defects.
• The effects of maternal stress on fetal development.
• The impact of prenatal exercise on maternal and fetal health.
• The role of routine ultrasound examinations in prenatal care.
• The effectiveness of non-pharmacological interventions for nausea and vomiting during pregnancy.
• The impact of maternal obesity on pregnancy outcomes.
• The role of folic acid supplementation in the prevention of neural tube defects.
• The effectiveness of smoking cessation interventions during pregnancy.
• The impact of maternal alcohol consumption on fetal development.
• The role of prenatal education in preparing expectant mothers for childbirth.

Labor and Delivery:

• The effectiveness of epidural analgesia in managing labor pain.
• The impact of birthing positions on labor outcomes.
• The role of continuous support during labor and delivery.
• The effectiveness of non-pharmacological pain relief methods during labor.
• The impact of induced labor on maternal and neonatal outcomes.
• The role of midwives in managing labor and delivery.
• The effectiveness of water birth in reducing labor pain.
• The impact of cesarean section on maternal and neonatal outcomes.
• The role of intrapartum fetal monitoring in preventing adverse outcomes.
• The effectiveness of active management of the third stage of labor in preventing postpartum hemorrhage.

Postpartum Care:

• The role of breastfeeding support in promoting successful breastfeeding.
• The impact of postpartum depression on mother-infant bonding.
• The effectiveness of skin-to-skin contact in promoting neonatal thermoregulation.
• The role of postpartum exercise in promoting maternal physical and mental health.
• The impact of early postpartum discharge on maternal and neonatal outcomes.
• The effectiveness of postpartum contraceptive counseling in preventing unplanned pregnancies.
• The role of routine newborn screening in the early detection of congenital disorders.
• The impact of maternal-infant rooming-in on breastfeeding success.
• The effectiveness of postpartum home visits in promoting maternal and newborn health.
• The role of pelvic floor exercises in preventing postpartum urinary incontinence.

Gynecological Disorders:

• The effectiveness of hormonal therapy in managing polycystic ovary syndrome.
• The impact of lifestyle modifications on the management of endometriosis.
• The role of screening in the early detection of cervical cancer.
• The effectiveness of non-surgical interventions for uterine fibroids.
• The impact of human papillomavirus vaccination on the incidence of cervical cancer.
• The role of hormonal replacement therapy in managing menopausal symptoms.
• The effectiveness of conservative management for ovarian cysts.
• The impact of early detection and treatment on the prognosis of ovarian cancer.
• The role of lifestyle modifications in the prevention of gynecological cancers.
• The effectiveness of surgical interventions for pelvic organ prolapse.

Reproductive Health:

• The role of contraceptive counseling in preventing unplanned pregnancies.
• The impact of long-acting reversible contraceptives on reducing the rate of unintended pregnancies.
• The effectiveness of fertility awareness-based methods in preventing pregnancy.
• The role of preconception care in promoting healthy pregnancies.
• The impact of sexually transmitted infections on reproductive health.
• The effectiveness of barrier methods in preventing sexually transmitted infections.
• The role of hormonal contraceptives in managing menstrual disorders.
• The impact of infertility on mental health.
• The effectiveness of assisted reproductive technologies in managing infertility.
• The role of male involvement in promoting reproductive health.

Maternal and Newborn Health:

• The impact of gestational diabetes on maternal and neonatal outcomes.
• The effectiveness of kangaroo mother care in promoting neonatal health.
• The role of antenatal corticosteroids in preventing neonatal respiratory distress syndrome.
• The impact of maternal anemia on neonatal outcomes.
• The effectiveness of newborn resuscitation in preventing neonatal mortality.
• The role of immunization in promoting maternal and newborn health.
• The impact of maternal mental health on neonatal outcomes.
• The effectiveness of neonatal intensive care in improving the survival of preterm infants.
• The role of early intervention services in promoting the development of high-risk infants.
• The impact of maternal-infant bonding on neonatal outcomes.

High-Risk Pregnancy:

• The role of antenatal care in managing high-risk pregnancies.
• The impact of multiple pregnancies on maternal and neonatal outcomes.
• The effectiveness of nutritional interventions in managing gestational diabetes.
• The role of bed rest in managing preterm labor.
• The impact of advanced maternal age on pregnancy outcomes.
• The effectiveness of antihypertensive medications in managing preeclampsia.
• The role of fetal surveillance in managing intrauterine growth restriction.
• The impact of preconception care on the outcomes of high-risk pregnancies.
• The effectiveness of interventions for preventing recurrent preterm birth.
• The role of specialist care in managing high-risk pregnancies.

Women’s Health Across the Lifespan:

• The impact of lifestyle modifications on the prevention of cardiovascular diseases in women.
• The effectiveness of breast cancer screening in early detection and treatment.
• The role of hormone replacement therapy in managing menopausal symptoms.
• The impact of osteoporosis on women’s health.
• The effectiveness of interventions for preventing urinary incontinence in women.
• The role of regular exercise in promoting mental health in women.
• The impact of domestic violence on women’s health.
• The effectiveness of interventions for promoting healthy eating in women.
• The role of stress management in preventing chronic diseases in women.
• The impact of depression on women’s health.

Menopausal Health:

• The impact of menopause on cardiovascular health.
• The effectiveness of hormonal replacement therapy in managing menopausal symptoms.
• The role of lifestyle modifications in managing menopausal weight gain.
• The impact of menopause on mental health.
• The effectiveness of non-hormonal interventions for managing hot flashes.
• The role of regular exercise in preventing osteoporosis in postmenopausal women.
• The impact of menopause on sexual health.
• The effectiveness of dietary interventions in managing menopausal symptoms.
• The role of stress management in promoting menopausal health.
• The impact of menopause on the risk of developing gynecological cancers.

Ethical and Legal Issues in Obstetric and Gynecological Nursing:

• The role of informed consent in obstetric and gynecological procedures.
• The impact of religious and cultural beliefs on women’s health decisions.
• The effectiveness of mandatory reporting of domestic violence in promoting women’s safety.
• The role of confidentiality in obstetric and gynecological care.
• The impact of legal restrictions on abortion services.
• The effectiveness of legal interventions in preventing female genital mutilation.
• The role of ethical considerations in assisted reproductive technologies.
• The impact of legal and ethical issues on the practice of obstetric and gynecological nursing.
• The effectiveness of legal interventions in promoting maternal and newborn health.
• The role of ethical considerations in the management of high-risk pregnancies.

The importance of research in obstetric and gynecological nursing cannot be overstated as it plays a crucial role in ensuring the health and well-being of both women and newborns. The diverse range of topics listed above provides a comprehensive overview of the various aspects of obstetric and gynecological nursing. It is our hope that this list will serve as a valuable resource for students and professionals seeking to expand their knowledge and contribute to the body of knowledge in this vital area of healthcare.

The Range of Obstetric and Gynecological Nursing Research Paper Topics

Obstetric and gynecological nursing is an essential branch of healthcare that focuses on the well-being of women during pregnancy, childbirth, and the postpartum period, as well as the diagnosis and treatment of diseases of the female reproductive system. The significance of this field is immense, as it plays a crucial role in ensuring the health and safety of both mothers and newborns, and in managing and preventing gynecological disorders. The scope of obstetric and gynecological nursing research paper topics is vast, encompassing a wide range of issues from pregnancy and prenatal care, labor and delivery, postpartum care, gynecological disorders, and much more.

Pregnancy and Prenatal Care

Proper care during pregnancy is essential for the health and well-being of both the mother and the baby. Prenatal care involves a series of regular check-ups and screenings to monitor the health of the mother and the developing fetus. Obstetric nurses play a crucial role in providing this care, educating expectant mothers about proper nutrition, exercise, and lifestyle habits, monitoring the progress of the pregnancy, and identifying and managing any potential complications. Some obstetric and gynecological nursing research paper topics in this area could include the effectiveness of different prenatal screening tests, the impact of maternal lifestyle habits on fetal development, or the role of prenatal education in preparing expectant mothers for childbirth.

Labor and Delivery

The process of labor and delivery is a critical period that requires skilled care and management to ensure the safety of both the mother and the baby. Obstetric nurses are involved in every stage of this process, from monitoring the progress of labor, providing pain relief, assisting with the delivery, and caring for the mother and newborn immediately after birth. Research topics in this area could include the effectiveness of different pain relief methods during labor, the impact of birthing positions on labor outcomes, or the role of continuous support during labor and delivery.

Postpartum Care

The postpartum period, or the time after childbirth, is a crucial time for both the mother and the newborn. Obstetric nurses provide care to the mother as she recovers from childbirth, monitor the newborn’s health and development, provide breastfeeding support, and educate the new parents on infant care. Some potential obstetric and gynecological nursing research paper topics in this area could include the impact of postpartum depression on mother-infant bonding, the effectiveness of skin-to-skin contact in promoting neonatal thermoregulation, or the role of postpartum exercise in promoting maternal physical and mental health.

Gynecological Disorders

Gynecological nursing involves the diagnosis and treatment of diseases of the female reproductive system. Gynecological nurses provide care to women with a variety of gynecological disorders such as polycystic ovary syndrome (PCOS), endometriosis, uterine fibroids, cervical cancer, and more. Research topics in this area could include the effectiveness of hormonal therapy in managing PCOS, the impact of lifestyle modifications on the management of endometriosis, or the role of screening in the early detection of cervical cancer.

The diverse range of obstetric and gynecological nursing research paper topics provides an opportunity for researchers to explore a variety of issues that affect women’s health. By conducting research in this field, nurses can contribute to the body of knowledge that informs clinical practice and helps improve outcomes for women and newborns.

In conclusion, obstetric and gynecological nursing is a vital field that plays a crucial role in ensuring the health and well-being of women and newborns. From pregnancy and prenatal care, labor and delivery, postpartum care, and the management of gynecological disorders, the scope of this field is vast. The wide range of obstetric and gynecological nursing research paper topics provides an opportunity for researchers to explore various aspects of this field and contribute to the improvement of women’s health.

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Translational researchers apply basic science discoveries made in the laboratory to inform clinical practice and improve people's health. The OB-GYN translational research team at the Indiana University School of Medicine performs a wide variety of research related to maternal and reproductive health, gynecologic cancers, and postmenopausal and women’s health.

Department translational researchers conduct groundbreaking research and make scientific advancements through cross-departmental and interdisciplinary collaborations. Our investigators are embedded in major research centers, including:

• IU Simon Comprehensive Cancer Center
• Indiana Center for Musculoskeletal Health
• Maternal Pediatric Precision in Therapeutics (MPRINT)

Translational Research Areas

Drug metabolism in pregnancy.

Collaborating with the Divisions of Maternal-Fetal Medicine and General Obstetrics and Gynecology , translational researchers study how pregnant people metabolize various drugs and medications. Because pregnancy changes the ways bodies metabolize medications, researchers must understand what medications do and don't work during pregnancy and the effects those medications have on pregnant people and their fetuses.

Gynecologic Oncology

Collaborating with the Division of Gynecologic Oncology, translational researchers study neoplasms, endometriosis, fibroids and gynecologic cancers. By utilizing cell culture systems and laboratory animal models, they better understand the processes of noncancerous growth and cancer development. These findings help develop treatment options that researchers test in clinical trials.

Health in Post-Reproductive Years

In collaboration with the Divisions of General Obstetrics and Gynecology and Gynecologic Oncology , researchers investigate how diet and exercise can improve health after menopause and impact recovery in cancer survivors. Their research encompasses many different aspects of aging, including the effects of aging on musculoskeletal health, the onset of age-associated cancers and the effects of menopause.

Sex Hormones

In collaboration with the Division of Reproductive Endocrinology and Infertility, translational researchers study the interface of transgender care and the effects of different sex hormones. By administering different hormones in cell cultures and laboratory animal models, researchers examine the effects of sex hormones on different biological processes and development.

OB-GYN Faculty Labs

In addition to collaborating with department divisions and interdisciplinary collaborations, OB-GYN translational researchers perform research in dedicated faculty labs. The labs conduct research and studies on specific topics. 

Brodeur Lab

The Brodeur Lab uses mouse models to study the immune system's role in ovarian aging. Studying physiological aging in the ovaries, marked by changes in hormones, tissues and cells of the ovaries and oocytes, is crucial to helping people age well. Findings from the lab inform prevention, diagnostic and treatment efforts related to ovarian health throughout the lifespan.    

Condello Lab

The Condello Lab studies the mechanisms that regulate ovarian cancer metastasis within the peritoneal space. The lab aims to develop innovative therapies to halt tumor dissemination and enhance clinical outcomes. Insights gained from these studies are instrumental in the development of groundbreaking therapies for ovarian cancer, potentially transforming patient care and prognosis.  

Hawkins Lab

The Hawkins Lab studies benign and malignant diseases in the female reproductive tract. Researchers in this lab study ovarian cancer from the perspective of the endometriotic tumor microenvironment and create models that recapitulate human disease. In addition, the lab trains gynecologists, emergency medicine physicians and medical, graduate, undergraduate and high school students.  

Quinney Lab

The Quinney Lab utilizes a clinical pharmacology and pharmacometrics approach to support drug development and personalized therapeutics, emphasizing maternal and pediatric populations. Lab members use pharmacometric approaches, including population pharmacokinetics (PopPK) and physiologically-based pharmacokinetic (PBPK) modeling, to integrate data from in vitro and preclinical studies to clinical trials and real-world applications. Research contributions include studies supporting the dosing and safety of misoprostol, nifedipine, and gabapentin in pregnant or lactating individuals and drug discovery and development work in Alzheimer's disease, cancer and other areas.  

The Smith lab studies how nutrition and bioactive components in foods can reduce the risk of chronic disease and improve women's health in aging. Ongoing research utilizes cell culture systems and animal models to inform clinical trials, which seek to understand how the gut microbiome can be targeted to improve immune function and musculoskeletal health. The lab has a track record of training fellows, residents, and students at all levels interested in translational research focused on women's health. 

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Obstetrics and Gynaecology

Obstetrics and gynaecology research papers/topics, necrotizing fasciitis of the anterior abdominal wall: a rare complication of neglected strangulated richter's epigastric hernia.

Necrotizing soft tissue infection (NSTI) is an aggressive and rapidly spreading soft tissue infection that could be associated with high mortality. Early diagnosis can be challenging and so a high index of suspicion is needed. Bedside ultrasonography (USG) and computed tomography (CT) scan could be employed to aid in diagnosis. The objective of this report is to describe the diagnostic process in a resource challenged setting and review the literature. We present an elderly patient with necro...

Acceptability of human immunodeficiency virus testing in patients with invasive cervical cancer in Kenya

Abstract/Overview Invasive cervical cancer (ICC) is common in areas where human immunodeficiency virus (HIV) is also prevalent. Currently, HIV seroprevalence as well as acceptability of HIV testing in ICC patients in Kenya is unknown. The objective of this study was to determine the acceptability of HIV testing among patients with ICC. Women with histologically verified ICC at Kenyatta National Hospital participated in the study. A structured questionnaire was administered to patients who...

Knowledge and practice about cervical cancer and pap smear testing among patients at Kenyatta National Hospital, Nairobi, Kenya

Abstract/Overview Invasive cervical cancer (ICC) is the leading cause of cancer-related death among women in developing countries. Population-based cyto-logic screening and early treatment does reduce morbidity and mortality associated with cervical cancer. Some of the factors related to the success of such a program include awareness about cervical cancer and its screening. The objective of this study was to assess knowledge and practice about cervical cancer and Pap smear testing among ...

Risk Association between Human Leucocyte Antigens (HLA) and Cervical Neoplasia in Kenyan women

Abstract/Overview Cervical cancer is the second most common cause of cancer mortality among women worldwide (Franco et al, 2003). Epidemiological studies have shown a strong link between human papilloma virus (HPV) infection and the development of cervical cancer (Franco et al, carcinogenic process (Chan et al, 2005). Most HPV infections are transient and regress spontaneously and only a minority of women develops persistent infection that with time may evolve into cervical intraepithelia...

Prevalence of human papillomavirus in women with invasive cervical carcinoma by HIV status in Kenya and South Africa

Abstract/Overview Data on the prevalence of human papillomavirus (HPV) types in cervical carcinoma in women with HIV are scarce but are essential to elucidate the influence of immunity on the carcinogenicity of different HPV types, and the potential impact of prophylactic HPV vaccines in populations with high HIV prevalence. We conducted a multicentre case–case study in Kenya and South Africa. During 2007–2009, frozen tissue biopsies from women with cervical carcinoma were tested for ...

Factors and Common Bacterial Pathogens Associated with Post-Caesarean Wound Sepsis at Hoima Regional Referral Hospital, Uganda

ABSTRACT Background: Post-caesarean wound sepsis is among the most common problem for patients who undergo caesarean section. It remains a common and widespread problem contributing to morbidity and mortality; this could be due to an increase in antimicrobial resistant bacterial pathogens. Therefore, a study to identify and document the factors associated with wound sepsis and common bacterial pathogens can provide solution to prevent incidence and establish microbiological mapping, and this ...

Prevalence, Immediate Maternal Complications and Factors Associated with Thrombocytopenia among Women Delivering at Kampala International University Teaching Hospital, Western Uganda

Table of contents Declaratiori .•..................................................................................................................................... i Approval ......................................................................................................................................... ii Dedication ...................................................................................................................................... iii Acknowledgement .............

Outcomes of Medical Versus Surgical Management of First Trimester Incomplete Abortion Among Women Admitted at Kampala International University Teaching Ho9pital

ABSTRACT Background: Outcomes of surgical versus medical management of first trimester incomplete abortion are poorly documented in Uganda and it is important to guide clinical practice. Objectives: To compare the effectiveness, secondary outcomes and satisfaction level between surgical and medical management of first trimçster incomplete abortion among women admitted at Kampala International University Teachng Hospital. Methodology: Prospective open labelled randomized clinical trial of 100...

Prevalence of primary Caesarean Section deliveries among primiparous and multiparous women at Iringa Regional Referral Hospital, Tanzania

Abstract Introduction: Primary Caesarean Section (CS) is an operation that is performed for the first time on a pregnant woman. Primary CS is of particular interest because it has an influence on future modes of delivery. There is also an issue about the original indication for the procedure both in a woman who has never tried her pelvis for vaginal delivery and a woman who has delivered vaginally in the past. Objectives: To determine the prevalence, indications, and outcomes of primary CS de...

Prevalence Of Premalignant Cervical Lesions And Associated Risk Factors Among Women Aged 21 - 69 Years At Dodoma Regional Referral Hospital, Tanzania

ABSTRACT Background Premalignant cervical lesions that precede cervical cancers are the highest in low income countries. However, in 2007 Tanzania had reported to have as high as 17 % with 9972 incident cases and 6695 deaths of cervical cancer. There is limited documented close association between individual risk factor(s) and prevalence of the pre-malignant cervical cancer. Objectives: This study was conducted to determine prevalence of premalignant cervical lesions and associated risks fac...

Rate Of Cervical Dilatation, Duration Of Active Labor And Rate Of Intervention Among Low-Risk Pregnant Women Delivering At Dodoma Regional Referral Hospital

ABSTRACT Background: Cervical dilation at the onset of the active phase of labor determines the rate of cervical dilatation, duration of the active phase of labor and the needs of intervention. Identifying the abnormality toward the natural progress of the active phase of labor is important because timely intervention has been observed to be controversial among developing countries during the current practice among health care providers due to different opinion on the onset of the active pha...

Incidence and Predictors of Maternal and Perinatal Mortality among Women with Severe Maternal Outcomes: A Tanzanian Facility-Based Survey for Improving Maternal and Newborn Care

Abstract Introduction. Maternal and perinatal mortality is still a major public health challenge in Tanzania, despite the ongoing government efforts to improve maternal and newborn care. Among the contributors to these problems is the high magnitude of severe maternal outcomes (maternal near-miss). ,e current study, therefore, aimed to identify the magnitude and predictors of maternal and perinatal mortality among women with severe maternal outcomes admitted to Dodoma Regional Referral Hospit...

Knowledge of the Human Papilloma Virus vaccines, and opinions of Gynaecologists on its implementation in Nigeria

Abstract  The objective of this study was to determine the knowledge and perception of Nigerian Obstetricians and Gynaecologists towards human papilloma virus vaccine use in Nigeria. A cross sectional study was conducted amongst participants that attended the 42nd Society of Gynaecology and Obstetrics of Nigeria. The findings revealed that 44.5% knew the correct HPV vaccine schedule. Regarding implementation in Nigeria, 87.4% suggested its incorporation into the national immunization progra...

Knowledge Dissemination and Evaluation in A Cervical Cancer Screening Implementation Program in Nigeria

Abstract Objectives: Our goals were to train health professionals in Nigeria using the text, "Planning and Implementing Cervical Cancer Prevention and Control Programs: A Manual for Managers", and then evaluate the knowledge dissemination process using a pre- and post-test assessment. The manual was developed by the ACCP, WHO, TARC, PATT-T,Engender Health, TI-TPTEGO, and PAT-TO with funding from the Gates Foundation. It is an inclusive guide to implementation and maintenance of screen-and-tre...

Anaesthetic Considerations for the Hiv Positive Parturient

ABSTRACT The HIV epidemic in children parallels that among women on account of perinatal transmission. A combination of antiretroviral therapy and elective caesarean section reduces the rate of vertical transmission to

Project topics in Obstetrics and gynaecology, Research works, Seminars, Projects, Papers, Essays in Obstetrics and gynaecology.

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