Developing a Depression Care Model for the Hill Tribes: A Family‐ and Community‐Based Participatory Research. Onnalin Singkhorn, Pawadee Hamtanon, Katemanee Moonpanane, Khanittha Pitchalard, Rachanee Sunsern, Yosapon Leaungsomnapa, Chananan Phokhwang. First Published: 12 October 2023. Abstract. Full text.
Major depressive disorder: Validated treatments and future challenges
Depression is a prevalent psychiatric disorder that often leads to poor quality of life and impaired functioning. Treatment during the acute phase of a major depressive episode aims to help the patient reach a remission state and eventually return to their baseline level of functioning. Pharmacotherapy, especially selective serotonin reuptake ...
Depression Treatments for Adults
APA's Clinical Practice Guideline recommends seven psychotherapy interventions as well as a second-generation antidepressant (selective serotonin reuptake inhibitors—SSRIs—serotonin-norepinephrine reuptake inhibitors—SNRIs—or norepinephrine/dopamine reuptake inhibitors—NDRIs) for the treatment of depression in adults.
Insights and Advances Into Treatments for Major Depression
Sachs and colleagues report data from a Phase III study that is aimed at assessing the extent to which cariprazine is an effective add-on treatment for individuals with major depression that have not responded to their current treatment.This study builds on earlier studies with cariprazine and on studies demonstrating the efficacy of other atypical antipsychotic medications as adjunctive ...
Prognosis and improved outcomes in major depression: a review
Abstract. Treatment outcomes for major depressive disorder (MDD) need to be improved. Presently, no clinically relevant tools have been established for stratifying subgroups or predicting outcomes ...
Experimental depression treatment is nearly 80% effective in controlled
A new type of magnetic brain stimulation brought rapid remission to almost 80% of participants with severe depression in a study conducted at the Stanford University School of Medicine. The treatment, known as Stanford accelerated intelligent neuromodulation therapy (SAINT) or simply Stanford neuromodulation therapy, is an intensive, individualized form of transcranial magnetic stimulation.
Major Depressive Disorder: Advances in Neuroscience Research and
As shown in Fig. Fig.1E, 1 E, the hot research topics in depression are as follows: depression management in primary care, interventions to prevent depression, the pathogenesis of depression, comorbidity of depression and other diseases, the risks of depression, neuroimaging studies of depression, and antidepressant treatment.
Novel and emerging treatments for major depression
Depression is common, costly, debilitating, and associated with increased risk of suicide. It is one of the leading global public health problems. Although existing available pharmacological treatments can be effective, their onset of action can take up to 6 weeks, side-effects are common, and recovery can require treatment with multiple different agents. Although psychosocial interventions ...
New and emerging treatments for major depressive disorder
Major depressive disorder (MDD) affects a substantial portion of the population; however, much is still unknown about the pathophysiology of this disorder. Treatment resistance highlights the heterogeneous nature of MDD and the need for treatments to target more than monoamine neurotransmission. This review summarizes research into the new and emerging targets of MDD. These include drugs such ...
Advances in depression research: second special issue, 2020, with
Molecular Psychiatry - Advances in depression research: second special issue, 2020, with highlights on biological mechanisms, clinical features, co-morbidity, genetics, imaging, and treatment
Six distinct types of depression identified in Stanford Medicine-led
Most of the improvement occurred within the first five days of treatment. The findings further demonstrate the promise of using biotypes to take the guesswork out of depression treatment. Further explorations of depression. The different biotypes also correlate with differences in symptoms and task performance among the trial participants.
Treatment outcomes for depression: challenges and opportunities
Treatment outcomes for depression: challenges and opportunities. Depressive disorders are common, costly, have a strong effect on quality of life, and are associated with considerable morbidity and mortality. Effective treatments are available: antidepressant medication and talking therapies are included in most guidelines as first-line treatments.
Yale Depression Research Program
Yale Depression Research Program. Operated jointly by the Yale University School of Medicine Department of Psychiatry and Connecticut Mental Health Center, the Yale Depression Research Program has, for over 30 years, been committed to advancing the treatment of depression. By engaging in studies that seek to elucidate the underlying ...
Depression
For further reading, the following articles, referenced in this video, are available at the Journal's website: Esketamine for Treatment-Resistant Depression — First FDA-Approved Antidepressant ...
Depression Research and Treatment: Vol 2012, No 1
Effects of Temperament and Character Profiles on State and Trait Depression and Anxiety: A Prospective Study of a Japanese Youth Population. Xi Lu, Zi Chen, Xiaoyi Cui, Masayo Uji, Wataru Miyazaki, Masako Oda, Toshiaki Nagata, Toshinori Kitamura, Takahiko Katoh. , 604684. First Published: 22 August 2012.
Research in Context: Treating depression
This special Research in Context feature explores the development of more effective ways to treat depression, including personalized treatment approaches and both old and new drugs. Choat / Adobe Stock. Everyone has a bad day sometimes. People experience various types of stress in the course of everyday life. These stressors can cause sadness ...
Depression
Depression (also known as major depression, major depressive disorder, or clinical depression) is a common but serious mood disorder. It causes severe symptoms that affect how a person feels, thinks, and handles daily activities, such as sleeping, eating, or working. To be diagnosed with depression, the symptoms must be present for at least 2 ...
Biological, Psychological, and Social Determinants of Depression: A
Treatment for depression exists, such as pharmacotherapy, cognitive behavioural therapy, and other modalities. A meta-analysis of randomized, placebo-controlled trials of patients shows that 56-60% of people respond well to active treatment with antidepressants ... This paper discusses key areas in depression research; however, an exhaustive ...
Depression Research Clinic
Participants for this research will be currently experiencing depression and will have not responded to treatment with antidepressants or have an intolerance to these types of medicines. Recent studies have shown a single infusion of ketamine to reduce suicidal ideation within 24 hours and to last for at least one week. We would like to ...
Depression (major depressive disorder)
Treatment. Medications and psychotherapy are effective for most people with depression. Your primary care doctor or psychiatrist can prescribe medications to relieve symptoms. However, many people with depression also benefit from seeing a psychiatrist, psychologist or other mental health professional.
Research and treatment approaches to depression
Depression is a major cause of disability worldwide, but we know little about the underlying fundamental biology. Research is hindered by the difficulties of modelling a disorder of higher ...
Depression: The Latest Research
Depression: The Latest Research. If you're one of more than 17 million adults or 3.2 million teens in the United States with major depression, you may know that treatment often falls short. The ...
Depression, anxiety improve in patients enrolled in care personalized
Kaiser Permanente study finds symptoms improved in both a "collaborative care" model and typical psychiatric care. A study comparing traditional psychiatric treatment of depression and anxiety with a team-based collaborative care approach found that patients in both models saw significant improvement of their symptoms, but the improvement was even stronger in the collaborative care approach.
The Impact of Sleep Deprivation in the Treatment of Depression: A
Introduction Depression is a pervasive and debilitating mental health disorder that affects millions of individuals worldwide. Despite the availability of various treatment modalities, a ...
Study Reveals Differences Between Psilocybin, Escitalopram in
New research offers fresh insights into how different major depressive disorder (MDD) treatments can transform brain dynamics. More specifically, this paper - appearing in Nature Mental Health - compares how psilocybin therapy and escitalopram alter the brain's functional hierarchical organization to treat depression. The results of the double-blind, phase II randomized controlled trial ...
Seasonal Affective Disorder: An Overview of Assessment and Treatment
Seasonal affective disorder or SAD is a recurrent major depressive disorder with a seasonal pattern usually beginning in fall and continuing into winter months. A subsyndromal type of SAD, or S-SAD, is commonly known as "winter blues.". Less often, SAD causes depression in the spring or early summer. Symptoms center on sad mood and low energy.
Screening for Depression, Anxiety, and Suicide Risk in Adults: A
This service provides referrals to local treatment facilities, support groups, and community-based organizations. It is a free, confidential, 24-hour-a-day, 365-day-a year information service, in English and Spanish, for individuals and family members needing treatment for a mental and/or substance use disorder.
Cognitive behavioral therapy enhances brain circuits to relieve depression
New research led by Stanford Medicine has found that it can — if a therapy is matched with the right patients. In a study of adults with both depression and obesity — a difficult-to-treat combination — cognitive behavioral therapy that focused on problem solving reduced depression in a third of patients.
Depression has a consistent mark in the brain even when symptoms are absent
Decades of neuroimaging research show minor changes in brain structure and connectivity. However, researchers have a limited understanding of the processes that cause mood-state shifts ...
Researchers discovered novel and unique neural signature for depression
Reward bias response is altered in patients with treatment-resistant depression ... This research was supported by the National Institutes of Health by award numbers UH3 NS103549, K01 MH116364, R21 NS104953, UH3 NS100549 and R01 MH114854; and the McNair Medical Institute at the Robert and Janice McNair Foundation. ...
COMMENTS
Developing a Depression Care Model for the Hill Tribes: A Family‐ and Community‐Based Participatory Research. Onnalin Singkhorn, Pawadee Hamtanon, Katemanee Moonpanane, Khanittha Pitchalard, Rachanee Sunsern, Yosapon Leaungsomnapa, Chananan Phokhwang. First Published: 12 October 2023. Abstract. Full text.
Depression is a prevalent psychiatric disorder that often leads to poor quality of life and impaired functioning. Treatment during the acute phase of a major depressive episode aims to help the patient reach a remission state and eventually return to their baseline level of functioning. Pharmacotherapy, especially selective serotonin reuptake ...
APA's Clinical Practice Guideline recommends seven psychotherapy interventions as well as a second-generation antidepressant (selective serotonin reuptake inhibitors—SSRIs—serotonin-norepinephrine reuptake inhibitors—SNRIs—or norepinephrine/dopamine reuptake inhibitors—NDRIs) for the treatment of depression in adults.
Sachs and colleagues report data from a Phase III study that is aimed at assessing the extent to which cariprazine is an effective add-on treatment for individuals with major depression that have not responded to their current treatment.This study builds on earlier studies with cariprazine and on studies demonstrating the efficacy of other atypical antipsychotic medications as adjunctive ...
Abstract. Treatment outcomes for major depressive disorder (MDD) need to be improved. Presently, no clinically relevant tools have been established for stratifying subgroups or predicting outcomes ...
A new type of magnetic brain stimulation brought rapid remission to almost 80% of participants with severe depression in a study conducted at the Stanford University School of Medicine. The treatment, known as Stanford accelerated intelligent neuromodulation therapy (SAINT) or simply Stanford neuromodulation therapy, is an intensive, individualized form of transcranial magnetic stimulation.
As shown in Fig. Fig.1E, 1 E, the hot research topics in depression are as follows: depression management in primary care, interventions to prevent depression, the pathogenesis of depression, comorbidity of depression and other diseases, the risks of depression, neuroimaging studies of depression, and antidepressant treatment.
Depression is common, costly, debilitating, and associated with increased risk of suicide. It is one of the leading global public health problems. Although existing available pharmacological treatments can be effective, their onset of action can take up to 6 weeks, side-effects are common, and recovery can require treatment with multiple different agents. Although psychosocial interventions ...
Major depressive disorder (MDD) affects a substantial portion of the population; however, much is still unknown about the pathophysiology of this disorder. Treatment resistance highlights the heterogeneous nature of MDD and the need for treatments to target more than monoamine neurotransmission. This review summarizes research into the new and emerging targets of MDD. These include drugs such ...
Molecular Psychiatry - Advances in depression research: second special issue, 2020, with highlights on biological mechanisms, clinical features, co-morbidity, genetics, imaging, and treatment
Most of the improvement occurred within the first five days of treatment. The findings further demonstrate the promise of using biotypes to take the guesswork out of depression treatment. Further explorations of depression. The different biotypes also correlate with differences in symptoms and task performance among the trial participants.
Treatment outcomes for depression: challenges and opportunities. Depressive disorders are common, costly, have a strong effect on quality of life, and are associated with considerable morbidity and mortality. Effective treatments are available: antidepressant medication and talking therapies are included in most guidelines as first-line treatments.
Yale Depression Research Program. Operated jointly by the Yale University School of Medicine Department of Psychiatry and Connecticut Mental Health Center, the Yale Depression Research Program has, for over 30 years, been committed to advancing the treatment of depression. By engaging in studies that seek to elucidate the underlying ...
For further reading, the following articles, referenced in this video, are available at the Journal's website: Esketamine for Treatment-Resistant Depression — First FDA-Approved Antidepressant ...
Effects of Temperament and Character Profiles on State and Trait Depression and Anxiety: A Prospective Study of a Japanese Youth Population. Xi Lu, Zi Chen, Xiaoyi Cui, Masayo Uji, Wataru Miyazaki, Masako Oda, Toshiaki Nagata, Toshinori Kitamura, Takahiko Katoh. , 604684. First Published: 22 August 2012.
This special Research in Context feature explores the development of more effective ways to treat depression, including personalized treatment approaches and both old and new drugs. Choat / Adobe Stock. Everyone has a bad day sometimes. People experience various types of stress in the course of everyday life. These stressors can cause sadness ...
Depression (also known as major depression, major depressive disorder, or clinical depression) is a common but serious mood disorder. It causes severe symptoms that affect how a person feels, thinks, and handles daily activities, such as sleeping, eating, or working. To be diagnosed with depression, the symptoms must be present for at least 2 ...
Treatment for depression exists, such as pharmacotherapy, cognitive behavioural therapy, and other modalities. A meta-analysis of randomized, placebo-controlled trials of patients shows that 56-60% of people respond well to active treatment with antidepressants ... This paper discusses key areas in depression research; however, an exhaustive ...
Participants for this research will be currently experiencing depression and will have not responded to treatment with antidepressants or have an intolerance to these types of medicines. Recent studies have shown a single infusion of ketamine to reduce suicidal ideation within 24 hours and to last for at least one week. We would like to ...
Treatment. Medications and psychotherapy are effective for most people with depression. Your primary care doctor or psychiatrist can prescribe medications to relieve symptoms. However, many people with depression also benefit from seeing a psychiatrist, psychologist or other mental health professional.
Depression is a major cause of disability worldwide, but we know little about the underlying fundamental biology. Research is hindered by the difficulties of modelling a disorder of higher ...
Depression: The Latest Research. If you're one of more than 17 million adults or 3.2 million teens in the United States with major depression, you may know that treatment often falls short. The ...
Kaiser Permanente study finds symptoms improved in both a "collaborative care" model and typical psychiatric care. A study comparing traditional psychiatric treatment of depression and anxiety with a team-based collaborative care approach found that patients in both models saw significant improvement of their symptoms, but the improvement was even stronger in the collaborative care approach.
Introduction Depression is a pervasive and debilitating mental health disorder that affects millions of individuals worldwide. Despite the availability of various treatment modalities, a ...
New research offers fresh insights into how different major depressive disorder (MDD) treatments can transform brain dynamics. More specifically, this paper - appearing in Nature Mental Health - compares how psilocybin therapy and escitalopram alter the brain's functional hierarchical organization to treat depression. The results of the double-blind, phase II randomized controlled trial ...
Seasonal affective disorder or SAD is a recurrent major depressive disorder with a seasonal pattern usually beginning in fall and continuing into winter months. A subsyndromal type of SAD, or S-SAD, is commonly known as "winter blues.". Less often, SAD causes depression in the spring or early summer. Symptoms center on sad mood and low energy.
This service provides referrals to local treatment facilities, support groups, and community-based organizations. It is a free, confidential, 24-hour-a-day, 365-day-a year information service, in English and Spanish, for individuals and family members needing treatment for a mental and/or substance use disorder.
New research led by Stanford Medicine has found that it can — if a therapy is matched with the right patients. In a study of adults with both depression and obesity — a difficult-to-treat combination — cognitive behavioral therapy that focused on problem solving reduced depression in a third of patients.
Decades of neuroimaging research show minor changes in brain structure and connectivity. However, researchers have a limited understanding of the processes that cause mood-state shifts ...
Reward bias response is altered in patients with treatment-resistant depression ... This research was supported by the National Institutes of Health by award numbers UH3 NS103549, K01 MH116364, R21 NS104953, UH3 NS100549 and R01 MH114854; and the McNair Medical Institute at the Robert and Janice McNair Foundation. ...